KEGG ORTHOLOGY: K04292

ORTHOLOGY: K04292

Entry

K04292                      KO

Symbol

S1PR2, EDG5

Name

sphingosine 1-phosphate receptor 2

Pathway

map04071

Sphingolipid signaling pathway

map04080

Neuroactive ligand-receptor interaction

Disease

H00605

Deafness, autosomal recessive

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K04292  S1PR2, EDG5; sphingosine 1-phosphate receptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04292  S1PR2, EDG5; sphingosine 1-phosphate receptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04292  S1PR2, EDG5; sphingosine 1-phosphate receptor 2
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Lipid
   Sphingolipid
    K04292  S1PR2, EDG5; sphingosine 1-phosphate receptor 2

Other DBs

GO:

0038036

Genes

HSA:	9294(S1PR2)

PTR:	107966508(S1PR2)

PPS:	100982485(S1PR2)

GGO:	129528887(S1PR2)

PON:	100435839(S1PR2)

PPYG:

129019336(S1PR2)

NLE:	100593506(S1PR2)

HMH:	116478435(S1PR2)

SSYN:

129460416(S1PR2)

MCC:	712143(S1PR2)

MCF:	102137829(S1PR2)

MTHB:

126942701

MNI:	105476896(S1PR2)

CSAB:

103233889(S1PR2)

CATY:

105571281(S1PR2)

PANU:

101017954(S1PR2)

TGE:	112613575(S1PR2)

MLEU:

105549725(S1PR2)

RRO:	104670488(S1PR2)

RBB:	108534479(S1PR2)

TFN:	117076623(S1PR2)

PTEH:

111527764(S1PR2)

CANG:

105520878(S1PR2)

CJC:	100392405(S1PR2)

SBQ:	101053473(S1PR2)

CIMI:

108283592(S1PR2)

ANAN:

105706108(S1PR2)

CSYR:

103249240(S1PR2)

MMUR:

105885599(S1PR2) 105885600

LCAT:

123634973(S1PR2)

ERUF:

138390107(S1PR2)

PCOQ:

105807834(S1PR2)

OGA:	100963552(S1PR2)

MMU:	14739(S1pr2)

MCAL:

110301758(S1pr2)

MPAH:

110327611(S1pr2)

RNO:	29415(S1pr2)

MCOC:

116073953(S1pr2)

ANU:	117714342(S1pr2)

ASYL:

127689366(S1pr2)

MUN:	110557851(S1pr2)

CGE:	100689183(S1pr2)

MAUA:

101835178(S1pr2)

PROB:

127231261(S1pr2)

PLEU:

114695204(S1pr2)

PMAV:

102911618(S1pr2)

MORG:

121451633(S1pr2)

MFOT:

126490508

AAMP:

119810126(S1pr2)

CNL:	130873058(S1pr2)

NGI:	103747572(S1pr2)

HGL:	101712710(S1pr2)

CPOC:

100714153(S1pr2)

CCAN:

109693173(S1pr2)

DORD:

105999073(S1pr2)

DSP:	122119757(S1pr2)

DMER:

138813826(S1pr2)

PLOP:

125348760(S1pr2)

NCAR:

124968751

SVUL:

306646724(S1PR2)

MMMA:

107145168(S1pr2)

ITI:	101961752(S1pr2)

OCU:	100008828(S1PR2)

OPI:	101520134(S1PR2)

OCZ:	121160409(S1PR2)

TUP:	102498030(S1PR2)

GVR:	103594758(S1PR2)

CFA:	484959(S1PR2)

CLUD:

112666490(S1PR2)

VVP:	112909679(S1PR2)

VLG:	121496128(S1PR2)

NPO:	129521285(S1PR2)

AML:	100469679(S1PR2)

UMR:	103678732(S1PR2)

UAH:	113242976(S1PR2)

UAR:	123777657(S1PR2)

ELK:

111162471

LLV:

125084982

MPUF:

101684504(S1PR2)

MNP:	132010963(S1PR2)

MLK:	131823505(S1PR2)

NVS:	122909745(S1PR2)

ORO:	101374876(S1PR2)

EJU:	114197800(S1PR2)

ZCA:	113917782(S1PR2)

MLX:	118005196(S1PR2)

MANO:

123834101(S1PR2)

NSU:	110593831(S1PR2)

LWW:	102747709(S1PR2)

FCA:	101088909(S1PR2)

PYU:	121013962(S1PR2)

PCOO:

112852699(S1PR2)

PBG:	122486849(S1PR2)

PVIV:

125161261(S1PR2)

LRUF:

124523906

LGF:	123605260(S1PR2)

AJU:

106989315

PTG:	102961190(S1PR2)

PPAD:

109254123(S1PR2)

PUC:

125930565

PLEZ:

122213943(S1PR2)

HHV:	120244474(S1PR2)

CCRU:

144234601(S1PR2)

BTA:	540305(S1PR2)

BOM:	102275208(S1PR2)

BIU:	109561578(S1PR2)

BJV:	133250642(S1PR2)

BBUB:

102411537(S1PR2)

BKE:	129625664(S1PR2)

BBIS:

104979837(S1PR2)

CHX:	102180585(S1PR2)

OAS:	101112052(S1PR2)

OCAN:

138440921(S1PR2)

BTAX:

128051496(S1PR2)

CSUM:

138086505(S1PR2)

ODA:	120863985(S1PR2)

CCAD:

122440438(S1PR2)

MREE:

136166447(S1PR2)

OVR:	110142910(S1PR2)

MBEZ:

129559422(S1PR2)

SSC:	100511551(S1PR2)

CFR:	102510201(S1PR2)

CBAI:

105068373(S1PR2)

CDK:	105087644(S1PR2)

VPC:	102527663(S1PR2)

BACU:

103020830(S1PR2)

BMUS:

118893454(S1PR2)

LVE:	103078956(S1PR2)

OOR:	101276279(S1PR2)

LALB:

132517642(S1PR2)

GMF:	115865180(S1PR2)

DDP:	132421785(S1PR2)

SCOO:

307183282(S1PR2)

DLE:	111166166(S1PR2)

PCAD:

102987854(S1PR2)

PSIU:

116752242(S1PR2)

PPHC:

136121050(S1PR2)

NASI:

112400123(S1PR2)

HAMP:

307052935(S1PR2)

ECB:	100058299(S1PR2)

EPZ:	103558068(S1PR2)

EAI:	106841521(S1PR2)

MYB:	102242018(S1PR2)

MYD:	102772495(S1PR2)

MMYO:

118658411(S1PR2)

MLF:	102437458(S1PR2) 102440602

MDT:	132235076(S1PR2)

MYUM:

139004910 139010925(S1PR2)

PKL:	118731234(S1PR2)

EFUS:

103301138(S1PR2)

POTS:

308250074(S1PR2)

MNA:	107533307(S1PR2)

DRO:	112301468(S1PR2)

AJM:	119037084(S1PR2)

PDIC:

114502870(S1PR2)

PHAS:

123828449(S1PR2)

MMF:	118616341(S1PR2)

PPAM:

129061418(S1PR2)

HAI:	109391638(S1PR2)

RFQ:	117037706(S1PR2)

PALE:

102897806(S1PR2)

PGIG:

120610879(S1PR2)

PVP:	105305587(S1PR2)

RAY:	107515121(S1PR2)

MJV:	108395487(S1PR2)

TOD:	119240936(S1PR2)

SARA:

101539886(S1PR2)

SFUM:

130029005(S1PR2)

SETR:

126030348(S1PR2)

LAV:	100663336(S1PR2)

TMU:

101358936

ETF:	101637926(S1PR2)

DNM:	101429208(S1PR2)

MDO:	100012444(S1PR2)

GAS:	123232043(S1PR2)

SHR:	100934061(S1PR2)

AFZ:

127544719

PCW:	110214166(S1PR2)

TVP:	118843175(S1PR2)

PBRV:

138157492(S1PR2)

MLAO:

141500273(S1PR2)

OAA:	100080873(S1PR2)

TACU:

119949431(S1PR2)

GGA:	100857976(S1PR2)

PCOC:

116241471(S1PR2)

MGP:	104915933(S1PR2)

CJO:	107307560(S1PR2)

NMEL:

110391859(S1PR2)

APLA:

119714845(S1PR2)

AACU:

137846445(S1PR2)

OJA:	118159230(S1PR2)

BCLA:

308454774(S1PR2)

ACYG:

106049786(S1PR2)

CATA:

118261058(S1PR2)

AFUL:

116500067(S1PR2)

LSR:	110475840 110481013(S1PR2)

VCHA:

128802096(S1PR2)

AIB:	137467400(S1PR2)

SCAN:

103824957(S1PR2)

PMOA:

120503690(S1PR2)

OTC:	121337879(S1PR2)

PRUF:

121358177(S1PR2)

ATRC:

139585900(S1PR2)

MATE:

118697466(S1PR2)

MAEN:

136570047(S1PR2)

GFR:	102034149(S1PR2)

FAB:	101818756(S1PR2)

PHI:	102114759(S1PR2)

PMAJ:

107199107(S1PR2)

CCAE:

111942579(S1PR2)

CBRC:

103621069(S1PR2)

ACOE:

138100189(S1PR2)

ZLE:	135460474(S1PR2)

ACHL:

103801574(S1PR2)

SVG:	106862989(S1PR2)

MMEA:

130588509(S1PR2)

CFAI:

136305296 136305861

SHAB:

115603400(S1PR2)

FPG:	101923216(S1PR2)

FCH:	102058941(S1PR2)

CCRI:

104164419(S1PR2)

SURA:

141937201(S1PR2)

ACHC:

115348435(S1PR2)

HLE:	104832603(S1PR2)

AGEN:

126043133

HHAR:

128147530(S1PR2)

BBUT:

142030574(S1PR2)

LDI:	104352398(S1PR2)

MNB:

103770758

EGZ:	104132300(S1PR2)

NNI:	104018399(S1PR2)

PCRI:

104036725(S1PR2)

PCAO:

104045284(S1PR2)

PARX:

142048835(S1PR2)

AFOR:

103901578(S1PR2)

CBOR:

142073959(S1PR2)

GSTE:

104253631(S1PR2)

CBOY:

140645194(S1PR2)

MAME:

142421342(S1PR2)

CNIC:

136000954(S1PR2)

NMAY:

308051100(S1PR2)

PGUU:

104470890(S1PR2)

PLET:

104627674(S1PR2)

EHS:	104508666(S1PR2)

CMAC:

104485455(S1PR2)

CUCA:

104059189

PCUR:

138733985(S1PR2)

BREG:

104635975(S1PR2)

GAME:

129198621(S1PR2)

OHA:	104330675(S1PR2)

ACAR:

104528064(S1PR2)

CEUR:

306730877(LOC306730877)

CPEA:

104397668(S1PR2)

CVF:	104286743(S1PR2)

CRID:

134507986(S1PR2)

LMIC:

141734827(S1PR2)

NARQ:

141478004(S1PR2)

AAM:	106500188(S1PR2)

AROW:

112976943(S1PR2)

DNE:	112997093(S1PR2)

SCAM:

104151318(S1PR2)

ASN:	102387515(S1PR2)

AMJ:	102564636(S1PR2)

GGN:	109301392(S1PR2)

CIZ:	142003023(S1PR2)

CMY:	102946279(S1PR2)

CCAY:

125627396(S1PR2)

LKP:	140900854(S1PR2)

NDS:	141974884(S1PR2)

DCC:	119846143(S1PR2)

CPIC:

101933350(S1PR2)

TST:	117888650(S1PR2)

EOB:	135891880(S1PR2)

CABI:

116832439(S1PR2)

MRV:	120390962(S1PR2)

EMQ:	137161392(S1PR2)

ACS:	100566126(s1pr2)

ASAO:

132767908(S1PR2)

PVT:	110070892(S1PR2)

SUND:

121920859(S1PR2)

PBI:	103051804(S1PR2)

PMUR:

107284226(S1PR2)

CTIG:

120301286(S1PR2)

TSR:	106545773(S1PR2)

PGUT:

117675554(S1PR2)

PCAE:

139310932(S1PR2)

APRI:

131193336(S1PR2)

PTEX:

113443343(S1PR2)

NSS:	113417657(S1PR2)

VKO:	123030085(S1PR2)

PMUA:

114587445(S1PR2)

PRAF:

128405214(S1PR2)

ZVI:	118075493(S1PR2)

HCG:	128347732(S1PR2)

GJA:	107118675(S1PR2)

STOW:

125427896(S1PR2)

EMC:	129346366(S1PR2)

XLA:	108711696(s1pr2.L) 108713332(s1pr2.S)

XTR:	100497836(s1pr2)

NPR:	108802287(S1PR2)

RTEM:

120933277(S1PR2)

ACAT:

141133275(S1PR2)

PADS:

140322956(S1PR2)

BBUF:

120986382(S1PR2)

BGAR:

122927175(S1PR2)

DTC:	141059533(S1PR2)

PWL:	138292922(S1PR2)

MUO:	115466072(S1PR2) 115474419 115475104

GSH:	117349543(S1PR2)

DRE:	170457(s1pr2)

DAES:

130221548(s1pr2)

SRX:	107711272 107754042

SANH:

107670429 107672500

SGH:	107587933 107596814

CCAR:

109081276(s1pr2) 109087177

CAUA:

113042399 113072797 113095440

CGIB:

127952816 127953315

PTET:

122341976(s1pr2)

LROH:

127162953(s1pr2)

GRF:	141316324(s1pr2)

PPRM:

120489261(s1pr2)

RKG:	130086765(s1pr2)

SCEP:

307165628(s1pr2)

MAMB:

125268880(s1pr2)

CIDE:

127509505

CERY:

137017852(s1pr2)

MASI:

127449968 127452108

TROS:

130561924(s1pr2)

TDW:	130426087(s1pr2)

MANU:

129431045(s1pr2)

PDAB:

135732303(s1pr2)

IPU:	108257233(s1pr2)

IFU:	128600398(s1pr2)

PHYP:

113536118

SMEO:

124375965(s1pr2)

TFD:	113648079(s1pr2)

TVC:	132864239(s1pr2)

CGAR:

128519091(s1pr2)

NGRA:

132900481(s1pr2)

TRN:	134301554(s1pr2)

AMEX:

103044709(s1pr2)

CMAO:

118806148(s1pr2)

EEE:	113591932(s1pr2)

CHAR:

105905765(s1pr2)

SPIL:

134077310(s1pr2)

ASAD:

121706004(s1pr2)

TRU:	105416471(s1pr2)

TFS:	130514511(s1pr2)

NCC:	104950881(s1pr2)

TBEN:

117492630(s1pr2)

CGOB:

115012767(s1pr2)

PGEO:

117451303(s1pr2)

GACU:

117548864(s1pr2)

EMAC:

134878450(s1pr2)

ELY:	117269073(s1pr2)

EFO:	125879036(s1pr2)

PLEP:

121957143(s1pr2)

SLUC:

116059517(s1pr2)

SVIT:

144530070(s1pr2)

ECRA:

117958179(s1pr2)

ESP:	116703066(s1pr2)

PFLV:

114569840

PFLT:

120575206(s1pr2)

GAT:	120827497(s1pr2)

PPUG:

119220169(s1pr2)

AFB:	129097991(s1pr2)

CLUM:

117734595(s1pr2)

PSWI:

130189273(s1pr2)

CANA:

137786684(s1pr2)

TBU:	306750439(s1pr2)

CVE:	137885551(s1pr2)

AMIR:

142938033(s1pr2)

MSAM:

119891233(s1pr2)

SCHU:

122868563(s1pr2)

EARM:

139300370(s1pr2)

CUD:	121503808(s1pr2)

SPUL:

138602528(s1pr2)

LMIX:

132995350(s1pr2)

HTC:	141810151(s1pr2)

ALAT:

119013703(s1pr2)

ASTR:

137609937(s1pr2)

PKLU:

139217153(s1pr2)

LCO:

104918673

MZE:	101465962(s1pr2)

ONL:

100693419

OAU:	116332762(s1pr2)

OLA:

101156326

OML:	112146768(s1pr2)

CSAI:

133422331(s1pr2)

XMA:

102218055

XCO:

114159904

XHE:

116735418

PRET:

103468734(s1pr2)

PFOR:

103143737

PLAI:

106938633

PMEI:

106915663

GAF:	122821549(s1pr2)

PPRL:

129363342(s1pr2)

CVG:	107083098(s1pr2)

CTUL:

119785310(s1pr2)

GMU:	124863433 124863700

NFU:	107378353(s1pr2)

KMR:	108243740(s1pr2)

ALIM:

106529128

NWH:	119421039(s1pr2)

LTU:	140272981(s1pr2)

MCEP:

124997712(s1pr2)

AOCE:

111574846(s1pr2)

EJA:	138197859(s1pr2)

BFRE:

138630905(s1pr2)

LCF:

108903000

CSEM:

103392577

POV:

109633932

SSEN:

122785291(s1pr2)

SSOE:

131475222(s1pr2)

HHIP:

117766459(s1pr2)

HSP:	118123460(s1pr2)

PPLT:

128458959(s1pr2)

SMAU:

118288820(s1pr2)

SDU:	111217755(s1pr2)

SLAL:

111660536

XGL:	120804812(s1pr2)

HCQ:	109519315(s1pr2)

SSCV:

125983878(s1pr2)

SBIA:

133515013(s1pr2)

PEE:	133415244(s1pr2)

PTAO:

133466249(s1pr2)

BPEC:

110167207(s1pr2)

ENY:	140358316(s1pr2)

MALB:

109966018

BSPL:

114860106(s1pr2)

SJO:	128379077(s1pr2)

SSCO:

133999887(s1pr2)

TTY:	137200989(s1pr2)

GMH:	115558756(s1pr2)

SASA:

106601285 106607212

STRU:

115171242 115199319

OTW:	112226082 112259195

OMY:	110486371 110538423

OGO:	123999468 124015653

ONE:	115104246 115110548

OKI:	109893480 109898514

OKE:	118365415 118384543(s1pr2)

OMM:	135554153 135555603

OCLA:

139364775 139421279

SALP:

112071158(s1pr2)

SNH:	120034171 120037147

SFON:

129830771(s1pr2) 129833157

CCLU:

121569070(s1pr2)

ELS:	105027799(s1pr2)

OEP:	134010786(s1pr2)

SFM:	108935861(s1pr2)

PKI:

111849354

AANG:

118216444(s1pr2) 118218228

AROT:

135242892(s1pr2) 135248570

CCOG:

133112280 133114864(s1pr2)

LOC:

102698209

PSPA:

121304531(s1pr2)

ARUT:

117402036 117962366

LCM:	102366454(S1PR2)

CMK:

103187565

RTP:	109918921 125488356

CPLA:

122552319

CPUN:

140468211(s1pr2)

HOC:

SCAU:

LERI:

HAKA:

BFO:	118411711 118412300

BBEL:

CLEP:

LVG:

ATEN:

XEN:

HSY:	130636833 130637033

RES:	135685445 135685736

» show all

Reference

PMID:10617617

Authors

An S, Zheng Y, Bleu T

Title

Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5.

Journal

J Biol Chem 275:288-96 (2000)
DOI:10.1074/jbc.275.1.288

Sequence

[hsa:9294]

LinkDB

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