KEGG ORTHOLOGY: K04436

ORTHOLOGY: K04436

Entry

K04436                      KO

Symbol

MAPK8IP3, JIP3

Name

mitogen-activated protein kinase 8 interacting protein 3

Pathway

map04010

MAPK signaling pathway

Disease

H02862

Neurodevelopmental disorder with or without variable brain abnormalities

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04436  MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3

Genes

HSA:	23162(MAPK8IP3)

PTR:	453825(MAPK8IP3)

PPS:	100983128(MAPK8IP3)

GGO:	101149371(MAPK8IP3)

PON:	100433097(MAPK8IP3)

PPYG:

129015938(MAPK8IP3)

NLE:	100597219(MAPK8IP3)

HMH:	116462519(MAPK8IP3)

SSYN:

129462849(MAPK8IP3)

MCC:	702388(MAPK8IP3)

MCF:	102122008(MAPK8IP3)

MTHB:

126944581

MNI:	105485837(MAPK8IP3)

CSAB:

103226225(MAPK8IP3)

CATY:

105573702(MAPK8IP3)

PANU:

100998275(MAPK8IP3)

TGE:	112614456(MAPK8IP3)

MLEU:

105529786(MAPK8IP3)

RRO:	104681565(MAPK8IP3)

RBB:	108519380(MAPK8IP3)

TFN:	117097840(MAPK8IP3)

PTEH:

111524084(MAPK8IP3)

CANG:

105522869(MAPK8IP3)

CJC:	100385627(MAPK8IP3)

SBQ:	101031887(MAPK8IP3)

CIMI:

108291000(MAPK8IP3)

ANAN:

105709808(MAPK8IP3)

CSYR:

103272848(MAPK8IP3)

MMUR:

105859586(MAPK8IP3)

LCAT:

123631456(MAPK8IP3)

PCOQ:

105813088(MAPK8IP3)

OGA:	100944518(MAPK8IP3)

MMU:	30957(Mapk8ip3)

MCAL:

110283834(Mapk8ip3)

MPAH:

110337999(Mapk8ip3)

RNO:	302983(Mapk8ip3)

MCOC:

116078619(Mapk8ip3)

ANU:	117710645(Mapk8ip3)

ASYL:

127693320(Mapk8ip3)

MUN:	110548686(Mapk8ip3)

CGE:	100750767(Mapk8ip3)

MAUA:

101835274(Mapk8ip3)

PROB:

127219530(Mapk8ip3)

PLEU:

114681241(Mapk8ip3)

MORG:

121463607(Mapk8ip3)

MFOT:

126498303

AAMP:

119811915(Mapk8ip3)

NGI:	103752429(Mapk8ip3)

HGL:	101716066(Mapk8ip3)

CPOC:

100725966(Mapk8ip3)

CCAN:

109690191(Mapk8ip3)

DORD:

105981913(Mapk8ip3)

DSP:	122123765(Mapk8ip3)

PLOP:

125340403(Mapk8ip3)

NCAR:

124970516

MMMA:

107146736(Mapk8ip3)

ITI:	101974038(Mapk8ip3)

OCU:

103347298

OPI:	101516463(MAPK8IP3)

TUP:	102482334(MAPK8IP3)

GVR:	103597588(MAPK8IP3)

CFA:	100684766(MAPK8IP3)

CLUD:

112640569(MAPK8IP3)

VVP:	112909052(MAPK8IP3)

VLG:	121486517(MAPK8IP3)

NPO:	129519647(MAPK8IP3)

AML:	100467835(MAPK8IP3)

UMR:	103668770(MAPK8IP3)

UAH:	113245083(MAPK8IP3)

UAR:	123783734(MAPK8IP3)

ELK:

111156025

LLV:

125090192

MPUF:

101687115(MAPK8IP3)

MNP:	132027035(MAPK8IP3)

MLK:	131819954(MAPK8IP3)

NVS:	122895713(MAPK8IP3)

ORO:	101363715(MAPK8IP3)

EJU:	114215486(MAPK8IP3)

ZCA:	113933703(MAPK8IP3)

MLX:	118021699(MAPK8IP3)

NSU:	110587886(MAPK8IP3)

LWW:	102738501(MAPK8IP3)

FCA:	101086776(MAPK8IP3)

PYU:	121019337(MAPK8IP3)

PCOO:

112853215(MAPK8IP3)

PBG:	122471844(MAPK8IP3)

PVIV:

125154277(MAPK8IP3)

LRUF:

124525533

LGF:	123589786(MAPK8IP3)

AJU:

106982759

PTG:	102953580(MAPK8IP3)

PPAD:

109278120(MAPK8IP3)

PUC:

125927150

PLEZ:

122209348(MAPK8IP3)

HHV:	120241510(MAPK8IP3)

BTA:	537598(MAPK8IP3)

BOM:	102272897(MAPK8IP3)

BIU:	109578226(MAPK8IP3)

BBUB:

102399975(MAPK8IP3)

BBIS:

104996923(MAPK8IP3)

CHX:	102190654(MAPK8IP3)

OAS:	101110293(MAPK8IP3)

BTAX:

128043876(MAPK8IP3)

CSUM:

138075400(MAPK8IP3)

ODA:	120872952(MAPK8IP3)

CCAD:

122432932(MAPK8IP3)

MREE:

136160413(MAPK8IP3)

OVR:	110132855(MAPK8IP3)

MBEZ:

129545232(MAPK8IP3)

SSC:	100521718(MAPK8IP3)

CFR:	102507992(MAPK8IP3)

CBAI:

105064877(MAPK8IP3)

CDK:	105099740(MAPK8IP3)

VPC:	102533572(MAPK8IP3)

BACU:

103005927(MAPK8IP3)

BMUS:

118881161(MAPK8IP3)

LVE:	103071003(MAPK8IP3)

OOR:	101282469(MAPK8IP3)

LALB:

132505582(MAPK8IP3)

DLE:	111185148(MAPK8IP3)

PCAD:

102992898(MAPK8IP3)

PSIU:

116739544(MAPK8IP3)

NASI:

112409363(MAPK8IP3)

ECB:	100067809(MAPK8IP3)

EPZ:	103559116(MAPK8IP3)

EAI:	106836211(MAPK8IP3)

MYB:	102261478(MAPK8IP3)

MYD:	102773245(MAPK8IP3)

MMYO:

118656290(MAPK8IP3)

MLF:	102434121(MAPK8IP3)

MDT:	132232903(MAPK8IP3)

MYUM:

139009194(MAPK8IP3)

PKL:	118703487(MAPK8IP3)

EFUS:

103290482(MAPK8IP3)

MNA:	107533394(MAPK8IP3)

DRO:	112298286(MAPK8IP3)

SHON:

118978770(MAPK8IP3)

AJM:	119058169(MAPK8IP3)

PDIC:

114509502(MAPK8IP3)

PHAS:

123807082(MAPK8IP3)

MMF:	118641408(MAPK8IP3)

PPAM:

129083590(MAPK8IP3)

HAI:	109385884(MAPK8IP3)

RFQ:	117019526(MAPK8IP3)

PALE:

102887004(MAPK8IP3)

PGIG:

120620227(MAPK8IP3)

PVP:	105303314(MAPK8IP3)

RAY:	107506017(MAPK8IP3)

MJV:	108384435(MAPK8IP3)

TOD:	119242046(MAPK8IP3)

SARA:

101543976(MAPK8IP3)

SFUM:

130042995(MAPK8IP3)

SETR:

126000898(MAPK8IP3)

LAV:	100666856(MAPK8IP3)

TMU:

101353898

ETF:	101656177(MAPK8IP3)

MDO:	100010499(MAPK8IP3)

GAS:	123231134(MAPK8IP3)

SHR:	100914535(MAPK8IP3)

AFZ:

127543386

PCW:	110221899(MAPK8IP3)

TVP:	118830515(MAPK8IP3)

PBRV:

138177737(MAPK8IP3)

OAA:	100088393(MAPK8IP3)

TACU:

119941876(MAPK8IP3)

GGA:	426986(MAPK8IP3)

PCOC:

116230327(MAPK8IP3)

MGP:	100539570(MAPK8IP3)

CJO:	107321018(MAPK8IP3)

TPAI:

128079400(MAPK8IP3)

LMUT:

125700558(MAPK8IP3)

NMEL:

110405985(MAPK8IP3)

APLA:

101804532(MAPK8IP3)

ACYG:

106041198(MAPK8IP3)

CATA:

118249119(MAPK8IP3)

AFUL:

116495268(MAPK8IP3)

TGU:	100227405(MAPK8IP3)

LSR:	110470171(MAPK8IP3)

SCAN:

103824367(MAPK8IP3)

PMOA:

120504010

OTC:	121335869(MAPK8IP3)

PRUF:

121350619(MAPK8IP3)

ATRC:

139598342(MAPK8IP3)

GFR:	102043533(MAPK8IP3)

FAB:	101815668(MAPK8IP3)

OMA:	130259224(MAPK8IP3)

PHI:	102110832(MAPK8IP3)

PMAJ:

107211149(MAPK8IP3)

CCAE:

111936225(MAPK8IP3)

CCW:	104684629(MAPK8IP3)

CBRC:

103623310(MAPK8IP3)

ACOE:

138118842(MAPK8IP3)

ETL:	114067344(MAPK8IP3)

ZAB:	102063799(MAPK8IP3)

ZLE:	135454095(MAPK8IP3)

ACHL:

103803907(MAPK8IP3)

SVG:	106861678(MAPK8IP3)

MMEA:

130583445(MAPK8IP3)

HRT:	120759898(MAPK8IP3)

SATI:

136368242(MAPK8IP3)

CCIC:

134050642(MAPK8IP3)

FPG:	101911650(MAPK8IP3)

FCH:	102058267(MAPK8IP3)

CCRI:

104163970(MAPK8IP3)

NNT:	104407879(MAPK8IP3)

SHAB:

115606601(MAPK8IP3)

ACUN:

113485827(MAPK8IP3)

TALA:

104365480(MAPK8IP3)

ACHC:

115335542(MAPK8IP3)

HALD:

104319507(MAPK8IP3)

HLE:	104832409(MAPK8IP3)

AGEN:

126034122

HHAR:

128134963(MAPK8IP3)

GCL:

127022218

LDI:	104349289(MAPK8IP3)

DPUB:

104300267(MAPK8IP3)

PPUS:

135180699(MAPK8IP3)

AVIT:

104268676(MAPK8IP3)

BRHI:

104492256(MAPK8IP3)

EGZ:	104135919(MAPK8IP3)

NNI:

104010775

PCRI:

104037681(MAPK8IP3)

PADL:

103917134(MAPK8IP3)

AFOR:

103895550(MAPK8IP3)

FGA:	104082716(MAPK8IP3)

GSTE:

104262971

CLV:	102088133(MAPK8IP3)

MUI:	104537274(MAPK8IP3)

PLET:

104625696(MAPK8IP3)

CMAC:

104473094(MAPK8IP3)

CUCA:

104068198(MAPK8IP3)

TEO:	104377843(MAPK8IP3)

BREG:

104632896(MAPK8IP3)

OHA:	104333657(MAPK8IP3)

ACAR:

104522978(MAPK8IP3)

CPEA:

104395360

CVF:

104287645

RTD:	128913280(MAPK8IP3)

CRID:

134519406(MAPK8IP3)

AAM:	106482375(MAPK8IP3)

AROW:

112968884(MAPK8IP3)

NPD:	112959872(MAPK8IP3)

TGT:	104570971(MAPK8IP3)

DNE:	112983394(MAPK8IP3)

SCAM:

104142260(MAPK8IP3)

ASN:	102378822(MAPK8IP3)

AMJ:	102571555(MAPK8IP3)

CPOO:

109313381(MAPK8IP3)

GGN:	109290690(MAPK8IP3)

PSS:	102443920(MAPK8IP3)

CMY:	102945157(MAPK8IP3)

CCAY:

125644146(MAPK8IP3)

DCC:	119862297(MAPK8IP3)

CPIC:

101944560(MAPK8IP3)

TST:	117883525(MAPK8IP3)

CABI:

116825489(MAPK8IP3)

MRV:	120373953(MAPK8IP3)

ACS:	100567029(mapk8ip3)

ASAO:

132781860(MAPK8IP3)

PVT:	110086698(MAPK8IP3)

SUND:

121914155(MAPK8IP3)

PBI:

103064436

PMUR:

107299390

CTIG:

120315752(MAPK8IP3)

PGUT:

117673108(MAPK8IP3)

APRI:

131185386(MAPK8IP3)

PTEX:

113438711(MAPK8IP3)

NSS:	113421847(MAPK8IP3)

VKO:	123024989(MAPK8IP3)

PMUA:

114583943(MAPK8IP3)

PRAF:

128402142(MAPK8IP3)

ZVI:	118092590(MAPK8IP3)

HCG:	128336408(MAPK8IP3)

GJA:	107124642(MAPK8IP3)

STOW:

125431918(MAPK8IP3)

EMC:	129338763(MAPK8IP3)

XLA:	108701610 108703170(mapk8ip3.S)

XTR:	100170186(mapk8ip3)

NPR:	108783724(MAPK8IP3)

RTEM:

120943378(MAPK8IP3)

BBUF:

121007405(MAPK8IP3)

BGAR:

122945222(MAPK8IP3)

PWL:	138261543(MAPK8IP3)

MUO:	115475518(MAPK8IP3)

GSH:	117345451(MAPK8IP3)

DRE:	100318355(mapk8ip3)

SRX:	107745855 107754341(mapk8ip3)

SANH:

107661179 107689052

SGH:	107552451 107567271(mapk8ip3)

CCAR:

109055087 109059401(mapk8ip3)

CAUA:

113043648 113046900(mapk8ip3)

CGIB:

127947592 127947659 127953599

PTET:

122338831(mapk8ip3)

LROH:

127162610(mapk8ip3)

OMC:	131537454(mapk8ip3)

PPRM:

120489692(mapk8ip3)

RKG:	130075207(mapk8ip3)

MAMB:

125279227(mapk8ip3)

CIDE:

127509669

CERY:

137017464(mapk8ip3)

MASI:

127450303 127451382

TROS:

130561995(mapk8ip3)

TDW:	130425572(mapk8ip3)

MANU:

129436281(mapk8ip3)

PDAB:

135758606 135770567

IPU:

108255773

IFU:	128601574(mapk8ip3)

PHYP:

113528073(mapk8ip3)

SMEO:

124396555(mapk8ip3)

TFD:	113638089(mapk8ip3)

TVC:	132861174(mapk8ip3)

CGAR:

128544199(mapk8ip3)

NGRA:

132868764(mapk8ip3)

TRN:	134335898(mapk8ip3)

AMEX:

103035578(mapk8ip3)

CMAO:

118821003(mapk8ip3)

EEE:	113580228(mapk8ip3)

CHAR:

105890690(mapk8ip3)

SPIL:

134076553(mapk8ip3)

TRU:	101062533(mapk8ip3)

TFS:	130515147(mapk8ip3)

TNG:	GSTEN00021804G001

LCO:	104930332(mapk8ip3)

NCC:	104942736(mapk8ip3)

TBEN:

117492642(mapk8ip3)

CGOB:

115011726(mapk8ip3)

PGEO:

117451205(mapk8ip3)

GACU:

117544127(mapk8ip3)

EMAC:

134877911(mapk8ip3)

ELY:	117268320(mapk8ip3)

EFO:	125879663(mapk8ip3)

PLEP:

121956631(mapk8ip3)

SLUC:

116065410(mapk8ip3)

ECRA:

117957957(mapk8ip3)

ESP:	116703729(mapk8ip3)

PFLV:

114569112(mapk8ip3)

GAT:	120827929(mapk8ip3)

PPUG:

119220463(mapk8ip3)

AFB:	129098052(mapk8ip3)

CLUM:

117735378(mapk8ip3)

PSWI:

130188217(mapk8ip3)

CANA:

137787030(mapk8ip3)

CVE:	137885553(mapk8ip3)

MSAM:

119886424(mapk8ip3)

CUD:	121529382(mapk8ip3)

SPUL:

138602843(mapk8ip3)

LMIX:

132995768(mapk8ip3)

ALAT:

119014508(mapk8ip3)

ASTR:

137609131(mapk8ip3)

MZE:	101469207(mapk8ip3)

ONL:	100696297(mapk8ip3)

OAU:	116314570(mapk8ip3)

OLA:	101157621(mapk8ip3)

OML:	112146222(mapk8ip3)

CSAI:

133421365(mapk8ip3)

XMA:	102235325(mapk8ip3)

XCO:	114159788(mapk8ip3)

XHE:	116736206(mapk8ip3)

PRET:

103469103(mapk8ip3)

PFOR:

103145403(mapk8ip3)

PLAI:

106957418(mapk8ip3)

PMEI:

106934110(mapk8ip3)

GAF:	122822340(mapk8ip3)

PPRL:

129363305(mapk8ip3)

CVG:	107101185(mapk8ip3)

CTUL:

119781765(mapk8ip3)

GMU:	124863202 124864123

NFU:	107376671(mapk8ip3)

KMR:	108242961(mapk8ip3)

ALIM:

106516473(mapk8ip3)

NWH:	119421122(mapk8ip3)

AOCE:

111565324(mapk8ip3)

EJA:	138198384(mapk8ip3)

BFRE:

138627715(mapk8ip3)

MCEP:

124998407(mapk8ip3)

CSEM:

103392988(mapk8ip3)

POV:

109642565

SSEN:

122785285

SSOE:

131475088(mapk8ip3)

HHIP:

117766716(mapk8ip3)

HSP:	118123771(mapk8ip3)

PPLT:

128459120(mapk8ip3)

SMAU:

118288461(mapk8ip3)

LCF:

108881021

SDU:	111230192(mapk8ip3)

SLAL:

111649098(mapk8ip3)

XGL:	120786036(mapk8ip3)

HCQ:	109514846(mapk8ip3)

SSCV:

125984233(mapk8ip3)

SBIA:

133514067(mapk8ip3)

PEE:	133414925(mapk8ip3)

PTAO:

133466037(mapk8ip3)

BPEC:

110158215(mapk8ip3)

ENY:	140357963(mapk8ip3)

MALB:

109958874(mapk8ip3)

BSPL:

114859950(mapk8ip3)

SJO:	128378505(mapk8ip3)

SSCO:

134000013(mapk8ip3)

GMH:	115531307(mapk8ip3)

SASA:

106583929 106600681(mapk8ip3)

STRU:

115170743(mapk8ip3) 115192107

OTW:	112246415(mapk8ip3) 112252174

OMY:	110521924 110538921(mapk8ip3)

OGO:	124000406(mapk8ip3) 124037925

ONE:	115109968(mapk8ip3) 115145218

OKI:	109893067(mapk8ip3) 109898245

OKE:	118358962 118384115(mapk8ip3)

OMM:	135556036(mapk8ip3) 135556073

OCLA:

139406889 139420892

SALP:

111971263 111981348

SNH:	120044435(mapk8ip3) 120052154

CCLU:

121550276 121569793

ELS:	105012833(mapk8ip3)

OEP:	134039078(mapk8ip3)

SFM:	108923925 108941826

PKI:	111836871 111847734

AANG:

118217348 118221015

AROT:

135243105 135248064

CCOG:

133114494 133121918

LOC:	102692769(mapk8ip3)

PSPA:

121300834(mapk8ip3) 121330953

ARUT:

117417980 117431353(mapk8ip3)

PSEX:

120543232(mapk8ip3)

LCM:	102346900(MAPK8IP3)

CMK:	103186050(mapk8ip3)

RTP:	109915594(mapk8ip3)

CPLA:

122560460(mapk8ip3)

HOC:	132825329(mapk8ip3)

LERI:

129707051(mapk8ip3)

PMRN:

LRJ:

PPYR:

CCRN:

RES:

Reference

PMID:12189133

Authors

Matsuura H, Nishitoh H, Takeda K, Matsuzawa A, Amagasa T, Ito M, Yoshioka K, Ichijo H

Title

Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade.

Journal

J Biol Chem 277:40703-9 (2002)
DOI:10.1074/jbc.M202004200

Sequence

[hsa:23162]

LinkDB

DBGET integrated database retrieval system