Homo sapiens (human): 23162
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Entry
23162 CDS
T01001
Symbol
MAPK8IP3, JIP-3, JIP3, JSAP1, NEDBA, SYD2, syd
Name
(RefSeq) mitogen-activated protein kinase 8 interacting protein 3
KO
K04436
mitogen-activated protein kinase 8 interacting protein 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
Disease
H02470
Neurodevelopmental disorder with structural brain abnormalities
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
23162 (MAPK8IP3)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Jnk-SapK_ap_N
WD40_2
JIP_LZII
ATG14
Rootletin
DUF1759
Motif
Other DBs
NCBI-GeneID:
23162
NCBI-ProteinID:
NP_055948
OMIM:
605431
HGNC:
6884
Ensembl:
ENSG00000138834
UniProt:
Q9UPT6
Structure
PDB
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All DBs
Position
16:1706195..1770351
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AA seq
1336 aa
AA seq
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MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVV
NVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKK
ELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIE
RSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKLVPAGDHWHLSDLGQ
LQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGV
GSKNSKRAREKRDSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLD
RTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEV
GNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELE
EELKRVKSEAIIARREPKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKE
RLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRPYPSVNIHY
KSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGR
LQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRP
NEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSRVWILTSTL
TTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGAD
GVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATE
VPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRPEPEPSGDP
TGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGT
LAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKS
FDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKL
GFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARP
GGIIHVYGDDSSDRAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDS
PAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMSQVKPVLSK
AERSHIIVWQVSYTPE
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgatggagatccagatggacgagggcggcggcgtggtggtgtaccaggacgactactgc
tccggctcggtgatgtcggagcgggtgtcgggcctggcgggctccatctaccgcgagttc
gagcgcctcatccactgctacgacgaggaggtggtcaaggagctcatgccgctggtggtg
aacgtgctggagaacctagactcggtgctcagcgagaaccaggagcacgaggtggagctg
gagctgctgcgcgaggacaacgagcagctgctcacccagtacgagcgtgagaaggcgctg
cgcaggcaggcggaggagaaattcattgagtttgaagatgctctggaacaagagaagaaa
gagctgcaaatccaggtggagcactacgagttccagacgcgccagctggagctgaaggcc
aagaactatgccgatcagatttcccggttggaggagcgggagtcggagatgaagaaggag
tacaatgccctgcaccagcggcacacagagatgatacagacctacgtggagcacattgag
aggtccaagatgcagcaggtcggaggaaacagccagaccgagagcagcctgccggggcgg
aggaaggagcgccccacctccctgaacgtgttccccctggctgacggcacggtacgtgca
cagatcgggggcaagctcgtgcctgcgggggaccactggcacctgagtgacctcggccag
ctgcagtccagctccagctaccagtgtccacaggatgaaatgtccgagtcaggccagtcc
tcggcggccgccacacccagcaccacaggcaccaagtccaacacgcccacatcctccgtg
ccctcggccgccgtcacacccctcaacgagagcctgcagcccctgggggactatggcgtg
ggctccaagaacagcaagcgtgcccgggagaagcgcgacagccgcaacatggaagtacag
gtcacccaggagatgcgcaacgtcagtataggcatgggcagcagtgacgagtggtctgat
gttcaagacattattgactccacgccagagctggacatgtgtccagagacccgcctggac
cgcacaggaagcagcccaacccagggcatcgtgaacaaagctttcggcatcaacaccgac
tccctgtaccatgagctgtcgacggcagggtctgaggtcatcggggatgtggacgaaggg
gccgacctcctaggggagttctcagtgcgcgatgatttctttggaatgggcaaagaagtg
gggaatctgctactggaaaactcacagcttctggaaaccaaaaacgccttgaatgtggtg
aagaatgacctgattgccaaggtcgaccagctgtccggggagcaggaggtgctgaggggc
gagttggaggctgctaagcaggccaaagtcaagctggaaaaccgtatcaaggagctggaa
gaggaactgaaaagagtgaagtccgaggccatcatcgcccgccgtgaacccaaagaagag
gcggaggatgtaagcagctatctctgtacagaatcggacaaaatccccatggcccagcgc
cgccgcttcacgcgggtggagatggcccgtgtgctcatggagcggaaccagtacaaggag
cggctgatggagctgcaggaggctgtgcggtggactgagatgatcagagcgtcccgagag
cacccatccgtccaggagaagaagaagtcgaccatctggcagttcttcagccgcctcttc
agctcttcctccagcccccctccggccaagcgcccctatccctcggtgaacatccactac
aagtcacccaccactgccggcttcagccagcgccgcaaccatgccatgtgcccgatctcg
gcaggcagccggcccctggaattcttccctgacgacgactgcacgtcctccgcccgtcga
gagcagaagcgcgagcagtaccgccaggtgcgtgagcacgtgcgtaacgacgacggccgt
ctgcaggcctgcggctggagcctgcccgccaagtacaagcagctgagtcccaacgggggc
caggaggacacgcggatgaagaacgtgccggtgccggtgtactgccgccctctggtggag
aaggaccccaccatgaagctgtggtgtgccgcgggcgtcaacctgagcgggtggaggccc
aatgaggacgacgctgggaatggagtcaagccagcgccaggccgcgatcccctgacctgc
gaccgcgaaggagacggcgagcccaagagcgcccacacgtctcccgagaagaagaaggcc
aaggagctccctgaaatggacgccacctccagccgggtgtggatcctgaccagcaccctg
accaccagcaaggtggtgatcatcgacgccaaccagccgggcacggtggtggaccagttc
accgtctgcaacgcgcacgtgctgtgcatctccagcatccccgcggccagcgacagcgac
taccctcccggggagatgttcctggacagcgacgtgaacccagaggacccgggcgcagat
ggcgtgctggccggtatcaccctggtgggctgtgccacccgctgcaacgtgccgcggagc
aactgctcctcccgaggggacaccccagtgctagacaaggggcagggggaggtggccacc
atcgccaacgggaaggtcaacccgtcccagtccacagaggaggccacagaggccacggag
gtgccagaccctgggcccagcgagccagagacagccacattgcggcccgggcctctcaca
gagcacgtcttcactgacccagccccgaccccgtcctctggcccccagcctggcagcgag
aacgggccagagcctgacagcagcagcacacggccagagccagagcccagcggggacccc
acgggagcaggcagcagtgctgcacccaccatgtggctgggagcccagaacggctggctc
tatgtgcactcggctgtggccaactggaagaagtgcctgcactccatcaagctgaaggat
tctgtgctgagcctggtgcatgtcaaaggccgtgtgctggtggctctggcggacgggacc
ctggccatcttccaccgtggtgaagatggccagtgggatctgagcaactatcacctaatg
gacctgggccacccgcaccactccatccgctgcatggctgttgtgtacgaccgcgtgtgg
tgtggctacaagaacaaggtgcacgtcatccagcccaagaccatgcagatagagaagtca
tttgacgcccacccgcggcgggagagccaggtgcggcagctggcgtggatcggcgatggc
gtatgggtgtccatccgcctggactccaccctgaggctctaccatgcacacacgcaccag
catctacaggacgtggacattgagccctacgtcagcaagatgctaggcactggcaagctg
ggtttctccttcgtacgcatcacggccctgcttgtcgcgggcagccggctctgggtgggc
accggcaacggagtggtcatctccatccccctgacagagactgtggtcctgcaccgaggc
cagctcctggggctccgagccaataagacatcccccacctctggggagggcgcccgtccc
gggggcatcatccacgtgtatggcgatgacagcagtgacagggcggccagcagcttcatc
ccctactgctccatggcccaggcccagctatgcttccatgggcaccgcgatgccgtgaag
ttctttgtctcggtgccagggaacgtgctggccaccctgaatgggagtgtgctggacagc
ccagccgagggccctgggccagctgcccctgcctcggaggtcgagggccagaagctgcgg
aacgtgctggtgctgagcggcggggagggctacatcgacttccgcattggagacggagag
gacgacgagacggaggagggcgcaggggacatgagccaggtgaagcccgtgctgtccaag
gcagagcgcagtcacatcatcgtgtggcaggtgtcctacacccccgagtga
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