KEGG ORTHOLOGY: K04610

ORTHOLOGY: K04610

Entry

K04610                      KO

Symbol

GRM8

Name

metabotropic glutamate receptor 8

Pathway

map04072

Phospholipase D signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

map04724

Glutamatergic synapse

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K04610  GRM8; metabotropic glutamate receptor 8
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04610  GRM8; metabotropic glutamate receptor 8
   04082 Neuroactive ligand signaling
    K04610  GRM8; metabotropic glutamate receptor 8
09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K04610  GRM8; metabotropic glutamate receptor 8
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04610  GRM8; metabotropic glutamate receptor 8
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04610  GRM8; metabotropic glutamate receptor 8
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04610  GRM8; metabotropic glutamate receptor 8
G protein-coupled receptors [BR:ko04030]
Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   K04610  GRM8; metabotropic glutamate receptor 8

Other DBs

GO:

0001642

Genes

HSA:	2918(GRM8)

PTR:	472502(GRM8)

PPS:	100990615(GRM8)

GGO:	101126075(GRM8)

PON:	100436264(GRM8)

PPYG:

129040964(GRM8)

NLE:	100583361(GRM8)

HMH:	116814309(GRM8)

SSYN:

129484961(GRM8)

MCC:	697465(GRM8)

MCF:	102128797(GRM8)

MTHB:

126949772

MNI:	105474850(GRM8)

CSAB:

103226837(GRM8)

CATY:

105598529(GRM8)

PANU:

100137389(GRM8)

TGE:	112620481(GRM8)

MLEU:

105550864(GRM8)

RRO:	104674474(GRM8)

RBB:	108530774(GRM8)

TFN:	117072754(GRM8)

PTEH:

111550184(GRM8)

CANG:

105518676(GRM8)

CJC:	100390040(GRM8)

SBQ:	101051755(GRM8) 104652145

CIMI:

108318444(GRM8)

ANAN:

105732091(GRM8)

CSYR:

103271836

MMUR:

105884824(GRM8)

LCAT:

123647414(GRM8)

PCOQ:

105818635

OGA:	100964145(GRM8)

MMU:	14823(Grm8)

MCAL:

110295944(Grm8)

MPAH:

110314875(Grm8)

RNO:	60590(Grm8)

MCOC:

116098642(Grm8)

ANU:	117720748(Grm8)

ASYL:

127678408(Grm8)

MUN:	110566052(Grm8)

CGE:

113832815

MAUA:

101822862(Grm8)

PROB:

127215369(Grm8)

PLEU:

114682535(Grm8) 114706111

MORG:

121463509(Grm8)

MFOT:

126501137

AAMP:

119806883(Grm8)

NGI:	103744576(Grm8)

HGL:	101697666(Grm8)

CPOC:

100725321(Grm8)

CCAN:

109677930

DORD:

105988342(Grm8)

DSP:	122121813(Grm8)

PLOP:

125347095(Grm8)

NCAR:

124990794

MMMA:

107144512(Grm8)

ITI:	101965504(Grm8)

OCU:

100344818

OPI:	101524260(GRM8)

TUP:	102479399(GRM8) 102480521

GVR:	103589458(GRM8)

CFA:	482270(GRM8)

CLUD:

112675030(GRM8)

VVP:	112928891(GRM8)

VLG:	121475145(GRM8)

NPO:	129498197(GRM8)

AML:	100472571(GRM8)

UMR:

103676623

UAH:	113263671(GRM8)

UAR:	123788996(GRM8)

ELK:

111152012

LLV:

125081285

MPUF:

101680915(GRM8)

MNP:	132015742(GRM8)

MLK:	131829712(GRM8)

NVS:	122905037(GRM8)

ORO:	101366084(GRM8)

EJU:	114210632(GRM8)

ZCA:	113911379(GRM8)

MLX:	118021043(GRM8)

NSU:	110589059(GRM8)

LWW:	102741743(GRM8)

FCA:	101098127(GRM8)

PYU:	121028390(GRM8)

PCOO:

112866814(GRM8)

PBG:	122488201(GRM8)

PVIV:

125161246(GRM8)

LRUF:

124524114

LGF:	123606803(GRM8)

AJU:

106986651

PTG:	102963124(GRM8) 107180340 107180341

PPAD:

109268930(GRM8)

PUC:

125930118

PLEZ:

122210772(GRM8)

HHV:	120239291(GRM8)

BTA:	538360(GRM8)

BOM:	102266408(GRM8)

BIU:	109557591(GRM8)

BBUB:

102408639(GRM8)

BBIS:

104982361(GRM8)

CHX:	102170113(GRM8)

OAS:	101108742(GRM8)

BTAX:

128046545(GRM8)

CSUM:

138079910(GRM8)

ODA:	120877310(GRM8)

CCAD:

122438597(GRM8)

MREE:

136170698(GRM8)

OVR:	110143083(GRM8)

MBEZ:

129552615(GRM8)

SSC:	100524120(GRM8)

CFR:	102506395(GRM8)

CBAI:

105063118(GRM8)

CDK:	105085351(GRM8)

VPC:	102534152(GRM8)

BACU:

103008338(GRM8)

BMUS:

118900767(GRM8)

LVE:	103084596 103086677(GRM8) 103090583

OOR:	101279194(GRM8)

LALB:

132524144(GRM8)

DLE:	111182367 111182370

PCAD:

102987895(GRM8)

PSIU:

116759854(GRM8)

NASI:

112408197(GRM8)

ECB:	100071655(GRM8)

EPZ:	103546392(GRM8)

EAI:	106839653(GRM8)

MYB:	102247202 102256646(GRM8)

MYD:	102764125 102766104(GRM8)

MMYO:

118666446(GRM8)

MLF:	102422181(GRM8)

MDT:	132242718(GRM8)

MYUM:

139016827(GRM8)

PKL:	118712325(GRM8)

EFUS:

103297351(GRM8)

MNA:	107537364(GRM8)

DRO:	112299876(GRM8)

SHON:

118989185(GRM8)

AJM:	119047695(GRM8)

PDIC:

114508144(GRM8)

PHAS:

123829771(GRM8)

MMF:	118619791(GRM8)

PPAM:

129063304(GRM8)

HAI:	109373927 109384602(GRM8)

RFQ:	117018342(GRM8)

PALE:

102898832(GRM8)

PGIG:

120601118(GRM8)

RAY:	107500220(GRM8) 107500567 107500568

MJV:	108393226(GRM8)

TOD:	119250560(GRM8)

SARA:

101546632(GRM8)

SFUM:

130027536(GRM8)

SETR:

126010660(GRM8)

LAV:	100662461(GRM8)

TMU:

101356899

ETF:	101657943(GRM8)

DNM:	101424413(GRM8)

MDO:	100014205(GRM8)

GAS:	123248834(GRM8)

SHR:	100927951(GRM8)

AFZ:

127538825

PCW:	110219222(GRM8)

TVP:	118850643(GRM8)

PBRV:

138160368

OAA:	100077390(GRM8)

TACU:

119933071(GRM8)

GGA:	427853(GRM8)

PCOC:

116244187(GRM8)

MGP:	100540879(GRM8)

CJO:	107308676(GRM8)

TPAI:

128073195(GRM8)

LMUT:

125689583(GRM8)

NMEL:

110392521(GRM8)

APLA:

101796179(GRM8)

ACYG:

106040497(GRM8)

CATA:

118254232(GRM8)

AFUL:

116492187(GRM8)

TGU:	751963(GRM8)

LSR:	110484507(GRM8)

SCAN:

103813484(GRM8) 115485246

PMOA:

120510775(GRM8)

OTC:	121336337(GRM8)

PRUF:

121355785(GRM8)

ATRC:

139588428(GRM8)

GFR:	102038282(GRM8)

FAB:	101815638(GRM8)

OMA:	130264966(GRM8)

PHI:	102110564(GRM8)

PMAJ:

107204551(GRM8)

CCAE:

111922977(GRM8)

CCW:	104686828(GRM8)

CBRC:

103623494

ACOE:

138099100(GRM8)

ETL:	114056988(GRM8)

ZAB:	102064229(GRM8)

ZLE:	135442672(GRM8)

ACHL:

103798820

SVG:	106854083(GRM8)

MMEA:

130580614

HRT:	120752175(GRM8)

SATI:

136361246(GRM8)

CCIC:

134043511(GRM8)

FPG:	101917886(GRM8)

FCH:	102049020(GRM8)

SHAB:

115605598(GRM8)

ACUN:

113491401(GRM8)

TALA:

104368267(GRM8)

ACHC:

115341731(GRM8)

HALD:

104321596

HLE:	104840386(GRM8)

AGEN:

126044472

HHAR:

128143214(GRM8)

GCL:

127014428

LDI:	104347948(GRM8)

DPUB:

104298404

PPUS:

135174817(GRM8)

AVIT:

104271501

BRHI:

104495822

EGZ:	104125669(GRM8)

NNI:	104010699(GRM8)

PADL:

103923638(GRM8)

AFOR:

103905201(GRM8)

CLV:	102094259(GRM8) 102097350

CMAC:

104478318

CUCA:

104055283(GRM8)

BREG:

104642441

OHA:	104330027(GRM8)

CPEA:

104393869(GRM8)

CVF:	104285231(GRM8)

RTD:	128913630(GRM8)

CRID:

134510251(GRM8)

AAM:	106495901 106495926(GRM8)

AROW:

112966622

NPD:	112957902(GRM8)

TGT:

104565836

DNE:	112990952(GRM8)

SCAM:

104151513(GRM8)

ASN:	102378960(GRM8)

AMJ:	102568236(GRM8)

CPOO:

109315657(GRM8)

GGN:	109292040(GRM8)

PSS:	102460589(GRM8)

CMY:	102937256(GRM8)

CCAY:

125630660(GRM8)

DCC:	119848935(GRM8)

CPIC:

101934943(GRM8)

TST:	117876085(GRM8)

CABI:

116833740

MRV:	120390719(GRM8)

ACS:	100564323(grm8)

ASAO:

132776288(GRM8)

PVT:	110080934(GRM8)

SUND:

121932265(GRM8)

PBI:	103052923 103055319

PMUR:

107286328

CTIG:

120297712

TSR:

106541012

PGUT:

117667749(GRM8)

APRI:

131202298(GRM8)

PTEX:

113445077(GRM8)

NSS:	113413038(GRM8)

VKO:	123020040(GRM8)

PMUA:

114605458(GRM8)

PRAF:

128421804(GRM8)

ZVI:	118088534 118091430(GRM8)

HCG:	128327688(GRM8)

GJA:	107108951(GRM8) 107109475

STOW:

125434473(GRM8)

EMC:	129336104(GRM8)

XLA:	108711155(grm8.L) 108712357(grm8.S)

XTR:	100497088(grm8)

NPR:

108804841

RTEM:

120931831(GRM8)

BBUF:

120985690(GRM8)

BGAR:

122927921(GRM8)

PWL:	138288254(GRM8)

MUO:	115479080(GRM8)

GSH:	117366915(GRM8)

DRE:	569768(grm8b) 792371(grm8a)

SRX:	107711511 107725917 107727747 107752308 107752348 107753676 107757749

SANH:

107656388 107658943 107659486 107691388 107698172

SGH:	107575719 107580973 107584025 107590553 107598887

CCAR:

109078020 109100611(grm8b) 109104261

CAUA:

113043387 113047874 113048659 113064599 113066985 113078781 113085493

CGIB:

127947010 127956924 127978812 128014226

PTET:

122330337(grm8b) 122342940(grm8a)

LROH:

127156775(grm8b) 127163833(grm8a)

OMC:	131534681(grm8b) 131539254(grm8a)

PPRM:

120470945(grm8a)

RKG:	130080047(grm8a) 130099289(grm8b)

MAMB:

125244557(grm8a) 125247403(grm8b)

CIDE:

127507610 127511514

CERY:

137014872(grm8b) 137024177(grm8a)

MASI:

127435277 127436334 127436511 127437735

TROS:

130547802(grm8a) 130551640(grm8b)

TDW:	130414123(grm8b) 130421200(grm8a)

MANU:

129432727(grm8a) 129433430(grm8b)

PDAB:

135745779(grm8a) 135749865 135781520(grm8b)

IPU:	108274531(grm8b) 108280139

IFU:	128617923(grm8b)

PHYP:

113529443 113532273

SMEO:

124392219(grm8b) 124401154(grm8a)

TFD:	113645420(grm8a) 113660057(grm8b)

TVC:	132856794(grm8b) 132858841(grm8a)

CGAR:

128506834(grm8b) 128534503(grm8a)

NGRA:

132869697(grm8a) 132881837(grm8b)

TRN:	134310641(grm8b)

AMEX:

103026501(grm8a) 103033497(grm8b)

CMAO:

118811724(grm8b) 118812663(grm8a)

EEE:	113575785(grm8) 113584046

CHAR:

105896030 105896692(grm8a)

SPIL:

134061726(grm8a) 134093858

TRU:

101069547

TFS:	130519546(grm8a)

LCO:	104931494 104934193

NCC:	104944301 104945723 104945754 104948093 104965158

TBEN:

117479696(grm8b) 117483284(grm8a)

CGOB:

115028464(grm8)

PGEO:

117439246(grm8a) 117448337

GACU:

117560026(grm8a)

EMAC:

134858057(grm8b) 134879549(grm8a)

ELY:	117249487(grm8a) 117262436

EFO:	125882854(grm8a) 125887005

PLEP:

121949981 121961236(grm8a)

SLUC:

116036256 116039759(grm8a)

ECRA:

117938374(grm8a) 117949709(grm8b)

ESP:	116672974(grm8) 116693719

PFLV:

114550112 114559879

GAT:	120809799(grm8b) 120817964(grm8a)

PPUG:

119195620(grm8b) 119210626(grm8a)

AFB:	129108674 129112340(grm8a)

CLUM:

117726035(grm8a) 117731862(grm8b)

PSWI:

130194729 130200237(grm8a)

CANA:

137791380(grm8a) 137803978

CVE:	137881553 137888108(grm8a)

MSAM:

119894372 119918200(grm8a)

SCHU:

122871009(grm8a) 122874707

CUD:	121505729(grm8a) 121515488

SPUL:

138599223(grm8a) 138612773(grm8b)

LMIX:

132956187(grm8a) 132972966

ALAT:

119024843(grm8b) 119032589(grm8a)

ASTR:

137589107(grm8a) 137593832

MZE:	101467017(grm8) 101480015

ONL:	100701565 100711588

OAU:	116309826(grm8a) 116319279 120433795

OLA:	101168089(grm8) 101169446

OML:	112141263(grm8b) 112156633(grm8a)

CSAI:

133423835(grm8a)

XMA:	102216909(grm8)

XCO:	114161283(grm8)

XHE:	116736890(grm8)

PRET:

103459427(grm8)

PFOR:

103129106(grm8)

PLAI:

106937317

PMEI:

106905925(grm8)

GAF:	122826748(grm8a)

PPRL:

129375511(grm8a)

CVG:	107088336 107092183

CTUL:

119774651(grm8a) 119798199

GMU:	124857424(grm8b) 124883161(grm8a)

NFU:	107384703(grm8) 107389496

KMR:	108235099(grm8a) 108250582

ALIM:

106521761 106525874

NWH:	119428149(grm8a)

AOCE:

111579073(grm8a) 111580258(grm8b)

EJA:	138202606(grm8a) 138206115

BFRE:

138627112(grm8a) 138633114

MCEP:

124999927(grm8a) 125015513

CSEM:

103379866 103382858

POV:	109624623 109632649 109648046

SSEN:

122767120(grm8a) 122776390

SSOE:

131457094(grm8a) 131469838(grm8b)

HHIP:

117757354(grm8a) 117763537(grm8b)

HSP:	118102017(grm8a) 118110256

PPLT:

128429179(grm8a) 128445122(grm8b)

SMAU:

118283033(grm8a) 118315856

LCF:	108888917(grm8a) 108903100(grm8b)

SDU:	111224565 111235974

SLAL:

111663684 111665055

XGL:	120793623 120800263(grm8a)

HCQ:	109513520 109513521 109522962

SSCV:

125970257 125992318(grm8a)

SBIA:

133493928(grm8a)

PEE:	133397216(grm8a) 133402589

PTAO:

133471684(grm8a) 133478179

BPEC:

110161404 110168821

ENY:	140348547 140368040(grm8a)

MALB:

109956402 109959817(grm8)

BSPL:

114857849(grm8b) 114862863(grm8a)

SJO:	128358952 128385098(grm8a)

SSCO:

133981650 134004208(grm8a)

GMH:	115532279(grm8) 115551429

SASA:

106561032 106576098 106576124 106584565(grm8) 106609203

STRU:

115180287 115192738 115197031 115198752

OTW:	112215038 112217165 112218221 112219491(grm8b)

OMY:	110490742 110492752 110500204 110521331(grm8b)

OGO:	123994629 124010467 124014402 124037023

ONE:	115121707 115134474 115144782

OKI:	109864619 109867642 109896752 109897772

OKE:	118359316(grm8b) 118365943 118392784 118396460

OMM:	135509569 135514811 135515978 135556619(grm8b)

OCLA:

139369629 139378698 139393098 139406453

SALP:

111951335 111962168 111962169 111971979 112069959

SNH:	120032326 120049340 120051754 120066625

CCLU:

121532040 121540543 121543659 121546218(grm8a)

ELS:	105007228 105025651 105030713

OEP:	134021251 134038074(grm8a)

SFM:	108918619 108931525

PKI:	111835584 111857075

AANG:

118218684 118231955

AROT:

135246059 135259000

CCOG:

133118818 133134827

LOC:	102690608(grm8)

PSPA:

121318317 121319787(grm8b)

ARUT:

117416245 117419481

PSEX:

120533985

LCM:	102353019(GRM8)

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

BFO:	118416211 118416912

BBEL:

SPU:

APLC:

ARUN:

AAMU:

139933929 139941812 139950362

AFIL:

140143528 140156486 140159274 140166164

SKO:

PFLL:

HIS:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

OBB:	114880931 114881446

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LBD:

MDL:

AGIF:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:	103313045 663070

TMOL:

ATD:

CSET:

HAXR:

NVL:	108560036 108569077

DCOR:

135797480(mGluR)

APLN:

OTU:

FOC:

TPAL:

IEL:

HAMR:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

HAZT:

EAF:	111700566 111707388

TCF:

PPOI:

TUT:

CSCU:

CVS:

ABRU:

UDV:	129217200 129231182

LPOL:

106460754 106462693 106464735 106464875 106478032

NAI:	NECAME_05605

PVUL:

PCAN:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111133091 111133092

OED:	125663860 125664023

MYI:

110457258

AIRR:

138335957

MMER:

123527500 123529486

RPHI:

132735750 132738891 132740698

DPOL:

MAEA:

OBI:

LJP:

LAK:

LLON:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

SPIS:

DGT:	114515879 114515881 114516165 114516325 114519295

XEN:	124443801 124444519 124445433

HMG:	100210315 100215785 105843064

HSY:	130644381 130648458

RES:	135682545 135684363 135688767

TAD:	TRIADDRAFT_29698

» show all

Reference

PMID:9299241

Authors

Scherer SW, Soder S, Duvoisin RM, Huizenga JJ, Tsui LC

Title

The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1.

Journal

Genomics 44:232-6 (1997)
DOI:10.1006/geno.1997.4842

Sequence

[hsa:2918]

LinkDB

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