Homo sapiens (human): 2918
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Entry
2918 CDS
T01001
Symbol
GRM8, GLUR8, GPRC1H, MGLUR8, mGlu8
Name
(RefSeq) glutamate metabotropic receptor 8
KO
K04610
metabotropic glutamate receptor 8
Organism
hsa
Homo sapiens (human)
Pathway
hsa04072
Phospholipase D signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04082
Neuroactive ligand signaling
hsa04724
Glutamatergic synapse
Network
nt06544
Neuroactive ligand signaling
Element
N01879
Glutamate-GRM-GNAI/O signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
2918 (GRM8)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
2918 (GRM8)
04082 Neuroactive ligand signaling
2918 (GRM8)
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
2918 (GRM8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
2918 (GRM8)
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
2918 (GRM8)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
2918 (GRM8)
G protein-coupled receptors [BR:
hsa04030
]
Metabotropic glutamate receptor family
Glutamate (metabotropic)
2918 (GRM8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ANF_receptor
7tm_3
NCD3G
Peripla_BP_6
Motif
Other DBs
NCBI-GeneID:
2918
NCBI-ProteinID:
NP_000836
OMIM:
601116
HGNC:
4600
Ensembl:
ENSG00000179603
UniProt:
O00222
Structure
PDB
PDBj
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All DBs
Position
7:complement(126438598..127252941)
Genome browser
AA seq
908 aa
AA seq
DB search
MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER
GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV
QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA
PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR
EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS
GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA
EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH
KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN
KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER
CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF
VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC
FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH
IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA
KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI
IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY
ISYSNHSI
NT seq
2727 nt
NT seq
+upstream
nt +downstream
nt
atggtatgcgagggaaagcgatcagcctcttgcccttgtttcttcctcttgaccgccaag
ttctactggatcctcacaatgatgcaaagaactcacagccaggagtatgcccattccata
cgggtggatggggacattattttggggggtctcttccctgtccacgcaaagggagagaga
ggggtgccttgtggggagctgaagaaggaaaaggggattcacagactggaggccatgctt
tatgcaattgaccagattaacaaggaccctgatctcctttccaacatcactctgggtgtc
cgcatcctcgacacgtgctctagggacacctatgctttggagcagtctctaacattcgtg
caggcattaatagagaaagatgcttcggatgtgaagtgtgctaatggagatccacccatt
ttcaccaagcccgacaagatttctggcgtcataggtgctgcagcaagctccgtgtccatc
atggttgctaacattttaagactttttaagatacctcaaatcagctatgcatccacagcc
ccagagctaagtgataacaccaggtatgactttttctctcgagtggttccgcctgactcc
taccaagcccaagccatggtggacatcgtgacagcactgggatggaattatgtttcgaca
ctggcttctgaggggaactatggtgagagcggtgtggaggccttcacccagatctcgagg
gagattggtggtgtttgcattgctcagtcacagaaaatcccacgtgaaccaagacctgga
gaatttgaaaaaattatcaaacgcctgctagaaacacctaatgctcgagcagtgattatg
tttgccaatgaggatgacatcaggaggatattggaagcagcaaaaaaactaaaccaaagt
gggcattttctctggattggctcagatagttggggatccaaaatagcacctgtctatcag
caagaggagattgcagaaggggctgtgacaattttgcccaaacgagcatcaattgatgga
tttgatcgatactttagaagccgaactcttgccaataatcgaagaaatgtgtggtttgca
gaattctgggaggagaattttggctgcaagttaggatcacatgggaaaaggaacagtcat
ataaagaaatgcacagggctggagcgaattgctcgggattcatcttatgaacaggaagga
aaggtccaatttgtaattgatgctgtatattccatggcttacgccctgcacaatatgcac
aaagatctctgccctggatacattggcctttgtccacgaatgagtaccattgatgggaaa
gagctacttggttatattcgggctgtaaattttaatggcagtgctggcactcctgtcact
tttaatgaaaacggagatgctcctggacgttatgatatcttccagtatcaaataaccaac
aaaagcacagagtacaaagtcatcggccactggaccaatcagcttcatctaaaagtggaa
gacatgcagtgggctcatagagaacatactcacccggcgtctgtctgcagcctgccgtgt
aagccaggggagaggaagaaaacggtgaaaggggtcccttgctgctggcactgtgaacgc
tgtgaaggttacaactaccaggtggatgagctgtcctgtgaactttgccctctggatcag
agacccaacatgaaccgcacaggctgccagcttatccccatcatcaaattggagtggcat
tctccctgggctgtggtgcctgtgtttgttgcaatattgggaatcatcgccaccaccttt
gtgatcgtgacctttgtccgctataatgacacacctatcgtgagggcttcaggacgcgaa
cttagttacgtgctcctaacggggatttttctctgttattcaatcacgtttttaatgatt
gcagcaccagatacaatcatatgctccttccgacgggtcttcctaggacttggcatgtgt
ttcagctatgcagcccttctgaccaaaacaaaccgtatccaccgaatatttgagcagggg
aagaaatctgtcacagcgcccaagttcattagtccagcatctcagctggtgatcaccttc
agcctcatctccgtccagctccttggagtgtttgtctggtttgttgtggatcccccccac
atcatcattgactatggagagcagcggacactagatccagagaaggccaggggagtgctc
aagtgtgacatttctgatctctcactcatttgttcacttggatacagtatcctcttgatg
gtcacttgtactgtttatgccattaaaacgagaggtgtcccagagactttcaatgaagcc
aaacctattggatttaccatgtataccacctgcatcatttggttagctttcatccccatc
ttttttggtacagcccagtcagcagaaaagatgtacatccagacaacaacacttactgtc
tccatgagtttaagtgcttcagtatctctgggcatgctctatatgcccaaggtttatatt
ataatttttcatccagaacagaatgttcaaaaacgcaagaggagcttcaaggctgtggtg
acagctgccaccatgcaaagcaaactgatccaaaaaggaaatgacagaccaaatggcgag
gtgaaaagtgaactctgtgagagtcttgaaaccaacacttcctctaccaagacaacatat
atcagttacagcaatcattcaatctga
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