KEGG ORTHOLOGY: K04639

ORTHOLOGY: K04639

Entry

K04639                      KO

Symbol

GNA13

Name

guanine nucleotide-binding protein subunit alpha-13

Pathway

map04022

cGMP-PKG signaling pathway

map04071

Sphingolipid signaling pathway

map04072

Phospholipase D signaling pathway

map04270

Vascular smooth muscle contraction

map04371

Apelin signaling pathway

map04611

Platelet activation

map04730

Long-term depression

map04810

Regulation of actin cytoskeleton

map04928

Parathyroid hormone synthesis, secretion and action

map05130

Pathogenic Escherichia coli infection

map05163

Human cytomegalovirus infection

map05200

Pathways in cancer

Disease

H02434

Diffuse large B-cell lymphoma, not otherwise specified

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
   04072 Phospholipase D signaling pathway
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
   04071 Sphingolipid signaling pathway
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
   04022 cGMP-PKG signaling pathway
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
  09156 Nervous system
   04730 Long-term depression
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
   04031 GTP-binding proteins
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
  Exosomal proteins of colorectal cancer cells
   K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
GTP-binding proteins [BR:ko04031]
Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 4 (G12/13)
    K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13

Genes

HSA:	10672(GNA13)

PTR:	454827(GNA13)

PPS:	100988877(GNA13)

GGO:	101152866(GNA13)

PON:	100461065(GNA13)

PPYG:

129017194(GNA13)

NLE:	100589821(GNA13)

HMH:	116458484(GNA13)

SSYN:

129469826(GNA13)

MCC:	718144(GNA13)

MCF:	102127819(GNA13)

MTHB:

126938356

MNI:	105469013(GNA13)

CSAB:

103243186(GNA13)

CATY:

105573047(GNA13)

PANU:

101010815(GNA13)

TGE:	112609527(GNA13)

MLEU:

105532531(GNA13)

RRO:	104675436(GNA13)

RBB:	108517753(GNA13)

TFN:	117067409(GNA13)

PTEH:

111542515(GNA13)

CANG:

105508914(GNA13)

CJC:	100394016(GNA13)

SBQ:	101034540(GNA13)

CIMI:

108281659(GNA13)

ANAN:

105718196(GNA13)

CSYR:

103260636(GNA13)

MMUR:

105861706(GNA13)

LCAT:

123650582(GNA13)

PCOQ:

105824802(GNA13)

OGA:	100963709(GNA13)

MMU:	14674(Gna13)

MCAL:

110304818(Gna13)

MPAH:

110331761(Gna13)

RNO:	303634(Gna13)

MCOC:

116076843(Gna13)

ANU:	117711084(Gna13)

MUN:	110560037(Gna13)

CGE:	100689071(Gna13)

MAUA:

101835577(Gna13)

PROB:

127218636(Gna13)

PLEU:

114690445(Gna13)

MORG:

121436098(Gna13)

MFOT:

126514965

AAMP:

119812989(Gna13)

NGI:	103742208(Gna13)

HGL:	101719378(Gna13)

CPOC:

100730887(Gna13)

CCAN:

109696711(Gna13)

DORD:

106003117(Gna13)

DSP:	122128327(Gna13)

PLOP:

125365237(Gna13)

NCAR:

124973058 124979863

MMMA:

107158364(Gna13)

OCU:

100352794

OPI:	101522146(GNA13)

TUP:	102488219(GNA13)

GVR:	103587812(GNA13)

CFA:	490901(GNA13)

CLUD:

112652903(GNA13)

VVP:	112920734(GNA13)

VLG:	121473119(GNA13)

NPO:	129510400(GNA13)

AML:	100474482(GNA13)

UMR:	103665670(GNA13)

UAH:	113265242(GNA13)

UAR:	123802930(GNA13)

ELK:

111158131

LLV:

125087041

MPUF:

101676878(GNA13)

MNP:	132004175(GNA13)

MLK:	131815704(GNA13)

NVS:	122906056(GNA13)

ORO:	101386508(GNA13)

EJU:	114216074(GNA13)

ZCA:	113939205(GNA13)

MLX:	118024340(GNA13)

NSU:	110570477(GNA13)

LWW:

102751138

FCA:	101087625(GNA13)

PYU:	121015328(GNA13)

PCOO:

112864473(GNA13)

PBG:	122485811(GNA13)

PVIV:

125151400(GNA13)

LRUF:

124513497

PTG:	102964498(GNA13)

PPAD:

109277047(GNA13)

PUC:

125927373

AJU:

106975340

HHV:	120230247(GNA13)

BTA:	505611(GNA13)

BOM:	102275435(GNA13)

BIU:	109573379(GNA13)

BBUB:

102390212(GNA13)

BBIS:

105000283(GNA13)

CHX:	102170818(GNA13)

OAS:	101117003(GNA13)

BTAX:

128064617(GNA13)

ODA:	120866595(GNA13)

CCAD:

122426182(GNA13)

MBEZ:

129544787(GNA13)

SSC:	100522824(GNA13)

CFR:	102523556(GNA13)

CBAI:

105063934(GNA13)

CDK:	105085708(GNA13)

VPC:	102542921(GNA13)

BACU:

103007094(GNA13)

BMUS:

118886324(GNA13)

LVE:	103071564(GNA13)

OOR:	101277931(GNA13)

DLE:	111182908(GNA13)

PCAD:

102989616(GNA13)

PSIU:

116745371(GNA13)

NASI:

112410234(GNA13)

ECB:	100062972(GNA13)

EPZ:	103553497(GNA13)

EAI:	106835353(GNA13)

MYB:	102252423(GNA13)

MYD:	102764420(GNA13)

MMYO:

118671564(GNA13)

MLF:	102436989(GNA13)

MDT:	132218615(GNA13)

PKL:	118726223(GNA13)

EFUS:

103293115(GNA13)

MNA:	107538305(GNA13)

DRO:	112316266(GNA13)

SHON:

119003776(GNA13)

AJM:	119036264(GNA13)

PDIC:

114502354(GNA13)

PHAS:

123816761(GNA13)

MMF:	118633864(GNA13)

PPAM:

129070232(GNA13)

HAI:	109380315(GNA13)

RFQ:	117013275(GNA13)

PALE:

102891607(GNA13)

PGIG:

120599999(GNA13)

PVP:	105297699(GNA13)

RAY:	107510298(GNA13)

MJV:	108392407(GNA13)

TOD:	119233057(GNA13)

SARA:

101539190(GNA13)

SETR:

126018343(GNA13)

LAV:	100664965(GNA13)

TMU:

101346987

ETF:	101645418(GNA13)

DNM:	101414963(GNA13)

MDO:	100024566(GNA13)

GAS:	123247196(GNA13)

SHR:	100932191(GNA13)

AFZ:

127560565

PCW:	110218195(GNA13)

TVP:	118846154(GNA13)

OAA:	103166871(GNA13)

GGA:	417434(GNA13)

PCOC:

116232471(GNA13)

MGP:	100540964(GNA13)

CJO:	107322109(GNA13)

TPAI:

128083115(GNA13)

LMUT:

125702156(GNA13)

NMEL:

110407202(GNA13)

APLA:

101801355(GNA13)

ACYG:

106034698(GNA13)

CATA:

118253924(GNA13)

AFUL:

116496726(GNA13)

TGU:	100223985(GNA13)

LSR:	110473974(GNA13)

SCAN:

103819970(GNA13)

PMOA:

120505454(GNA13)

OTC:	121338294(GNA13)

PRUF:

121363416(GNA13)

GFR:	102040291(GNA13)

FAB:	101812192(GNA13)

OMA:	130260494(GNA13)

PHI:	102099584(GNA13)

PMAJ:

107212551(GNA13)

CCAE:

111937573(GNA13)

CCW:	104696029(GNA13)

CBRC:

103620076(GNA13)

ETL:	114060688(GNA13)

ZAB:	102072742(GNA13)

ZLE:	135455311(GNA13)

ACHL:

103797437(GNA13)

SVG:	106856973(GNA13)

MMEA:

130586259(GNA13)

HRT:	120760940(GNA13)

SATI:

136369477(GNA13)

FPG:	101922831(GNA13)

FCH:	102052233(GNA13)

CCRI:

104156397(GNA13)

NNT:	104406093(GNA13)

SHAB:

115616828(GNA13)

ACUN:

113486831(GNA13)

TALA:

104364962(GNA13)

ACHC:

115341158(GNA13)

HALD:

104314263(GNA13)

HLE:	104838711(GNA13)

AGEN:

126043580

GCL:

127023973

CSTI:

104556662(GNA13)

LDI:	104342392(GNA13)

MNB:	103781356(GNA13)

DPUB:

104302182(GNA13)

AVIT:

104277477(GNA13)

BRHI:

104502367(GNA13)

EGZ:	104132822(GNA13)

NNI:	104014357(GNA13)

PCRI:

104030963(GNA13)

PCAO:

104043920(GNA13)

PADL:

103916715(GNA13)

AFOR:

103902427(GNA13)

FGA:	104070701(GNA13)

GSTE:

104258907(GNA13)

CLV:	102084052(GNA13)

MUI:	104547727(GNA13)

PGUU:

104467650(GNA13)

PLET:

104619761(GNA13)

EHS:	104508909(GNA13)

CMAC:

104476698(GNA13)

CUCA:

104061899(GNA13)

TEO:	104374740(GNA13)

BREG:

104639304(GNA13)

OHA:	104329923(GNA13)

ACAR:

104523460(GNA13)

CPEA:

104393316(GNA13)

CVF:	104295068(GNA13)

RTD:	128917876(GNA13)

AAM:	106493143(GNA13)

AROW:

112966899(GNA13)

NPD:	112953660(GNA13)

TGT:	104565219(GNA13)

DNE:	112982543(GNA13)

SCAM:

104146776(GNA13)

ASN:	102376261(GNA13)

AMJ:	102568562(GNA13)

CPOO:

109314956(GNA13)

GGN:	109296855(GNA13)

PSS:	102458860(GNA13)

CMY:	102940587(GNA13)

CCAY:

125621745(GNA13)

DCC:	119842627(GNA13)

CPIC:

101953084(GNA13)

TST:	117887642(GNA13)

CABI:

116822478(GNA13)

MRV:	120383144(GNA13)

ACS:	100554119(gna13)

ASAO:

132767758(GNA13)

PVT:	110085885(GNA13)

SUND:

121921524(GNA13)

PBI:	103050681(GNA13)

PMUR:

107282571(GNA13)

CTIG:

120300037(GNA13)

TSR:	106553054(GNA13)

PGUT:

117662931(GNA13)

APRI:

131189902(GNA13)

PTEX:

113443166(GNA13)

NSS:	113419429(GNA13)

VKO:	123033089(GNA13)

PMUA:

114588210(GNA13)

PRAF:

128407252(GNA13)

ZVI:	118079645(GNA13)

HCG:	128343341(GNA13)

GJA:	107105951(GNA13)

STOW:

125428521(GNA13)

EMC:	129327370(GNA13)

XLA:	108701204(gna13.L) 496349(gna13.S)

XTR:	100145489(gna13)

NPR:	108802992(GNA13)

RTEM:

120919355(GNA13)

BBUF:

121003271(GNA13)

BGAR:

122923241(GNA13)

MUO:	115473477(GNA13)

GSH:	117367864(GNA13)

DRE:	326825(gna13a) 336333(gna13b)

SRX:	107709641 107719992 107721501 107734232

SANH:

107654495 107660858 107688114 107692049

SGH:	107554062 107584085 107590387 107601276

CCAR:

109049849 109049931 109100123 109109108

CAUA:

113056064 113081926 113098973 113112106

CGIB:

127951169 127952108 127969155 128025210 128030253

PTET:

122339221(gna13b) 122355266(gna13a)

LROH:

127158773(gna13b) 127174542(gna13a)

OMC:	131536152(gna13b) 131551427(gna13a)

PPRM:

120464018 120489648(gna13b)

RKG:	130075835(gna13b) 130088630(gna13a)

MAMB:

125255403(gna13a) 125271647(gna13b)

CIDE:

127509439 127523407

CERY:

137007889(gna13a) 137017705(gna13b)

MASI:

127423674 127427249 127450851 127451758

TROS:

130561398(gna13b) 130568723(gna13a)

TDW:	130425758(gna13b) 130438916(gna13a)

MANU:

129420380 129420410 129420411 129421149 129433978(gna13b)

IPU:	108273768(gna13a) 108278714(gna13b)

IFU:	128617557(gna13a) 128622253(gna13b)

PHYP:

113527443 113528528

SMEO:

124388927(gna13a) 124396690(gna13b)

TFD:	113637145(gna13a) 113659226(gna13b)

TVC:	132838846(gna13a) 132860607(gna13b)

TRN:	134321382(gna13a) 134335866(gna13b)

AMEX:

103022306(gna13a) 103046194(gna13b)

CMAO:

118809485(gna13a) 118821059(gna13b)

EEE:	113574856 113580257

CHAR:

105888894(gna13a) 105899987(gna13b)

TRU:	101065558 101071876

TFS:	130514840(gna13b) 130530704

TNG:	GSTEN00010504G001 GSTEN00027029G001

LCO:	104923415 104927178

NCC:

104946516

TBEN:

117469241(gna13b) 117473605

CGOB:

115012229 115025027

PGEO:

117451038(gna13b) 117464507

GACU:

117544552 117551504

EMAC:

134870300 134877977(gna13b)

ELY:	117247232 117268272(gna13b)

EFO:	125878913(gna13b) 125880536

PLEP:

121957290(gna13b) 121958546

SLUC:

116045102(gna13b) 116061103

ECRA:

117937186 117958637(gna13b)

ESP:	116671786 116702591

PFLV:

114547969 114569558

GAT:	120819191 120827658(gna13b)

PPUG:

119212736 119220611(gna13b)

AFB:	129091104 129098123(gna13b)

CLUM:

117734523(gna13b) 117749238

PSWI:

130188346(gna13b) 130203241

MSAM:

119915709 119918667(gna13b)

SCHU:

122867246 122869561(gna13b)

CUD:	121528175 121529287(gna13b)

ALAT:

119009746 119013756(gna13b)

MZE:	101466738 101472915

ONL:	100701321 100712037

OAU:	116325955 116332737(gna13b)

OLA:	101159749 101162018 101175626

OML:	112154003 112157938(gna13b)

CSAI:

133419600 133422790(gna13b)

XMA:	102222912 102227062(gna13)

XCO:	114148609 114151980(gna13)

XHE:	116726921(gna13) 116735936

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122821330(gna13b) 122822843

PPRL:

129363206(gna13b) 129368295

CVG:	107100329 107102520

CTUL:

119771741 119778522

GMU:	124862732 124864591 124875331

NFU:	107387703 107391564

KMR:	108228367 108248446

ALIM:

106519019 106530025

NWH:	119421454(gna13b) 119424061

AOCE:

111567436 111586729

MCEP:

124998048(gna13b)

CSEM:

103381794 103393488

POV:	109640373 109642241

SSEN:

122759349 122785486

HHIP:

117753076 117765823(gna13b)

HSP:	118100669 118122986(gna13b)

PPLT:

128426825 128458016(gna13b)

SMAU:

118288004 118288516(gna13b)

LCF:	108876453 108898004(gna13b)

SDU:	111219813 111236257

SLAL:

111667200 111673547

XGL:	120794244 120806440(gna13b)

HCQ:	109508599 109516320

SSCV:

125983964 125991759

SBIA:

133495659 133515144(gna13b)

PEE:	133414353(gna13b) 133417741

PTAO:

133466394(gna13b) 133469564

BPEC:

110164386(gna13)

MALB:

109964702 109967924

BSPL:

114845814 114860741(gna13b)

SJO:	128378260(gna13b) 128380975

SASA:

106589443 106594878 106606258

STRU:

115156644 115171929 115201224 115208564

OTW:	112223394 112224319 112224721

OMY:	100305179 110485327 110491343 118938365

OGO:	124020574 124040078 124048122

ONE:	115106329 115144100

OKI:	109865520 109870070 109876168 109886145

OKE:	118357427 118368606 118382664

SALP:

111967821

SNH:	120029965 120042580 120046110

CCLU:

121547385 121551455 121569987 121584357

ELS:	105012792 105026577

SFM:	108937123 108940086

PKI:	111848291 111856756(gna13)

AANG:

118216503(gna13b) 118219543

LOC:	102687288(gna13)

PSPA:

121295594 121296219

ARUT:

117423695 117424191

PSEX:

120517146(gna13b)

LCM:	102364864(GNA13)

CMK:	103175515(gna13a)

RTP:	109931209(gna13a)

CPLA:

122562184

HOC:	132828016(gna13a)

LERI:

129708281(gna13a)

PMRN:

116946263 116949541

LRJ:	133346399 133353421 133353633

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

PPOI:

VDE:

VJA:

DFR:

LPOL:

106463454 106470070 106478447

PMEO:

CBR:

PCAN:

OSN:

OVI:	T265_10834

RES:

135692287

AQU:

105312217

» show all

Reference

PMID:2508088

Authors

Strathmann M, Wilkie TM, Simon MI

Title

Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.

Journal

Proc Natl Acad Sci U S A 86:7407-9 (1989)
DOI:10.1073/pnas.86.19.7407

Reference

PMID:7791744

Authors

Kabouridis PS, Waters ST, Escobar S, Stanners J, Tsoukas CD

Title

Expression of GTP-binding protein alpha subunits in human thymocytes.

Journal

Mol Cell Biochem 144:45-51 (1995)
DOI:10.1007/bf00926739

Sequence

[hsa:10672]

LinkDB

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