KEGG   ORTHOLOGY: K05069
Entry
K05069                      KO                                     
Symbol
IL2RB, CD122
Name
interleukin 2 receptor beta
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04144  Endocytosis
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
Disease
H02525  Disorders of innate immunity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04151 PI3K-Akt signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04659 Th17 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05202 Transcriptional misregulation in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05162 Measles
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04090 CD molecules
    K05069  IL2RB, CD122; interleukin 2 receptor beta
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05069  IL2RB, CD122; interleukin 2 receptor beta
CD molecules [BR:ko04090]
 Proteins
  K05069  CD122, IL2RB; interleukin 2 receptor, beta
Other DBs
GO: 0004911
Genes
HSA: 3560(IL2RB)
PTR: 470203(IL2RB)
PPS: 100992438(IL2RB)
GGO: 101139583(IL2RB)
PON: 100460977(IL2RB)
NLE: 100581366(IL2RB)
MCC: 696331(IL2RB)
MCF: 102138714(IL2RB)
MTHB: 126963717
MNI: 105464497(IL2RB)
CSAB: 103223268(IL2RB)
CATY: 105575817(IL2RB)
PANU: 101014683(IL2RB)
TGE: 112633515(IL2RB)
RRO: 104682498(IL2RB)
RBB: 108512733(IL2RB)
TFN: 117070006(IL2RB)
PTEH: 111549045(IL2RB)
CANG: 105527810(IL2RB)
CJC: 100394910(IL2RB)
SBQ: 101030332(IL2RB)
CSYR: 103258838(IL2RB)
MMUR: 105883739(IL2RB)
LCAT: 123639296(IL2RB)
PCOQ: 105805206(IL2RB)
OGA: 100957798(IL2RB)
MMU: 16185(Il2rb)
MCAL: 110310694(Il2rb)
MPAH: 110335025(Il2rb)
RNO: 25746(Il2rb)
MCOC: 116075473(Il2rb)
MUN: 110548465(Il2rb)
CGE: 113832088
MAUA: 101831461(Il2rb)
PLEU: 114694353(Il2rb)
MORG: 121461444(Il2rb)
MFOT: 126515825
AAMP: 119823009(Il2rb)
NGI: 103748643(Il2rb)
HGL: 101726369(Il2rb)
CPOC: 100730639(Il2rb)
CCAN: 109698250(Il2rb)
DORD: 105992027(Il2rb)
DSP: 122119318(Il2rb)
NCAR: 124981877
OPI: 101523537(IL2RB)
TUP: 102467660(IL2RB)
GVR: 103606392(IL2RB)
CFA: 403439(IL2RB)
CLUD: 112668470(IL2RB)
VVP: 112929101(IL2RB)
VLG: 121490488(IL2RB)
AML: 100478292(IL2RB)
UMR: 103676409(IL2RB)
UAR: 123780861(IL2RB)
ELK: 111157559
LLV: 125107622
MPUF: 101674646(IL2RB)
NVS: 122891322(IL2RB)
ORO: 101366322(IL2RB)
EJU: 114218365(IL2RB)
ZCA: 113923121(IL2RB)
MLX: 117998718(IL2RB)
NSU: 110578110(IL2RB)
LWW: 102733398(IL2RB)
FCA: 101092622(IL2RB)
PBG: 122472705(IL2RB)
LRUF: 124501540
PTG: 102965369(IL2RB)
PPAD: 109265527(IL2RB)
AJU: 106981084(IL2RB)
HHV: 120241202(IL2RB)
BTA: 104968644(IL2RB) 510185
BOM: 102284639(IL2RB) 106700824
BIU: 109559534(IL2RB)
BBIS: 105003412(IL2RB)
OAS: 101107088(IL2RB)
CCAD: 122423665(IL2RB) 122423666
SSC: 100621776(IL2RB)
CFR: 102524470(IL2RB)
CBAI: 105073156(IL2RB)
CDK: 105101578(IL2RB)
VPC: 102526550(IL2RB)
BACU: 103006990(IL2RB)
LVE: 103071005(IL2RB)
OOR: 101271954(IL2RB)
DLE: 111186349(IL2RB)
PCAD: 102995923(IL2RB)
PSIU: 116760998(IL2RB)
ECB: 100069676(IL2RB)
EPZ: 103564462(IL2RB)
EAI: 106837581(IL2RB)
MYB: 102241115(IL2RB)
MYD: 102768408(IL2RB)
MMYO: 118651872(IL2RB)
MLF: 102420320(IL2RB)
MNA: 107545294(IL2RB)
PKL: 118730561(IL2RB)
HAI: 109394467(IL2RB)
DRO: 112321925(IL2RB)
SHON: 119002352(IL2RB)
AJM: 119060429(IL2RB)
PDIC: 114513750(IL2RB)
PHAS: 123816246(IL2RB)
MMF: 118624074(IL2RB)
RFQ: 117029472(IL2RB)
PALE: 102883396(IL2RB)
PGIG: 120614851(IL2RB)
PVP: 105311493(IL2RB)
RAY: 107519288(IL2RB)
MJV: 108392662(IL2RB)
TOD: 119247294(IL2RB)
SARA: 101540128(IL2RB)
LAV: 100669139(IL2RB)
TMU: 101344371
ETF: 101664105(IL2RB)
DNM: 101440447(IL2RB)
MDO: 100025393(IL2RB)
GAS: 123249336(IL2RB)
SHR: 100913275(IL2RB)
PCW: 110205742(IL2RB)
OAA: 100092851(IL2RB)
GGA: 100859707(IL2RB)
PCOC: 116233307(IL2RB)
MGP: 104911125(IL2RB)
CJO: 107313789(IL2RB)
NMEL: 110393218(IL2RB)
APLA: 101791719(IL2RB)
ACYG: 106035899(IL2RB)
AFUL: 116502307(IL2RB)
TGU: 101232975(IL2RB)
LSR: 110483875(IL2RB)
SCAN: 103813230(IL2RB)
PMOA: 120510114(IL2RB)
OTC: 121342420(IL2RB)
PRUF: 121361198(IL2RB)
GFR: 102031500(IL2RB)
FAB: 101809303(IL2RB)
PHI: 102106386(IL2RB)
PMAJ: 107204849(IL2RB)
CCAE: 111935345(IL2RB)
CCW: 104696293(IL2RB)
CBRC: 103618066(IL2RB)
ETL: 114055414(IL2RB)
ZAB: 102071658(IL2RB)
ACHL: 103811052(IL2RB)
FPG: 101915263(IL2RB)
FCH: 102058748(IL2RB)
CLV: 102091469(IL2RB)
EGZ: 104134213(IL2RB)
NNI: 104021675(IL2RB)
PLET: 104623814(IL2RB)
PCRI: 104037786
PCAO: 104047662(IL2RB)
ACUN: 113475953(IL2RB)
TALA: 104369209(IL2RB)
PADL: 103924145(IL2RB)
AFOR: 103907726(IL2RB)
ACHC: 115352724(IL2RB)
HALD: 104316499(IL2RB)
HLE: 104842809(IL2RB)
AGEN: 126047795
GCL: 127029358
CCRI: 104169334(IL2RB)
CSTI: 104557104(IL2RB)
EHS: 104515386(IL2RB)
CMAC: 104487050(IL2RB)
MUI: 104545018(IL2RB)
FGA: 104083494(IL2RB)
GSTE: 104260064(IL2RB)
LDI: 104343967(IL2RB)
MNB: 103771298(IL2RB)
OHA: 104332382(IL2RB)
NNT: 104409153(IL2RB)
DPUB: 104302045(IL2RB)
PGUU: 104465982(IL2RB)
ACAR: 104520854(IL2RB)
CPEA: 104396058(IL2RB)
AVIT: 104273383
CVF: 104283649(IL2RB)
CUCA: 104065861(IL2RB)
TEO: 104376813(IL2RB)
BRHI: 104494165(IL2RB)
AAM: 106488409(IL2RB)
AROW: 112969360(IL2RB)
NPD: 112947763(IL2RB)
TGT: 104576752(IL2RB)
DNE: 112993906(IL2RB)
SCAM: 104150195(IL2RB)
ASN: 102376875(IL2RB)
AMJ: 102571730(IL2RB)
CPOO: 109316634(IL2RB)
GGN: 109296052(IL2RB)
PSS: 102449512(IL2RB)
CMY: 102936500(IL2RB)
CPIC: 101932173(IL2RB)
TST: 117880784(IL2RB)
CABI: 116824117(IL2RB)
MRV: 120396028(IL2RB)
ACS: 103278848(il2rb)
PVT: 110075925(IL2RB)
SUND: 121930375(IL2RB)
PBI: 112541087(IL2RB)
PMUR: 107302587(IL2RB)
CTIG: 120312416(IL2RB)
TSR: 106555941(IL2RB)
PGUT: 117655570(IL2RB)
VKO: 123028920(IL2RB)
PMUA: 114605576(IL2RB)
ZVI: 118090827(IL2RB)
GJA: 107120056(IL2RB)
STOW: 125435340(IL2RB)
XTR: 101731938(il2rb)
RTEM: 120945328(IL2RB)
BBUF: 120978814(IL2RB)
BGAR: 122943734(IL2RB)
DRE: 793920(il2rb)
PPRM: 120462286(il2rb)
MAMB: 125273756(il2rb)
IPU: 108272990(il2rb) 108273212
SMEO: 124381757(il2rb)
TFD: 113650520(il2rb)
TRU: 101076872
LCO: 104936154(il2rb)
NCC: 104964346
ELY: 117254604 117268216(il2rb)
EFO: 125879093(il2rb) 125885780
PLEP: 121941886 121957046(il2rb)
SLUC: 116042721 116065251(il2rb)
ECRA: 117952358 117957756(il2rb)
ESP: 116703789
PFLV: 114563754(csf2rb) 114563768 114570378(il2rb)
GAT: 120828204(il2rb)
PPUG: 119217935 119221110(il2rb)
MSAM: 119885295(il2rb) 119898625
ALAT: 119014395(il2rb) 119028782
OLA: 101165891 105354598(csf2rb)
OML: 112137100 112146641(il2rb)
ALIM: 106520638 106522494(csf2rb)
NWH: 119422104(il2rb)
AOCE: 111579444 111579883(csf2rb)
MCEP: 124997324(il2rb)
SSEN: 122771096 122785459(il2rb)
HHIP: 117759424 117765836(il2rb)
HSP: 118116518 118124013(il2rb)
LCF: 108877635
XGL: 120785060(il2rb) 120800036
HCQ: 109520288
MALB: 109972408(il2rb)
STRU: 115170931(il2rb) 115196369
ELS: 105009012(il2rb) 105029657
LOC: 102688112(il2rb)
PSPA: 121309365(il2rb)
LCM: 102367350
CMK: 103189779
RTP: 109914787(il2rb)
 » show all
Reference
PMID:2785715
  Authors
Hatakeyama M, Tsudo M, Minamoto S, Kono T, Doi T, Miyata T, Miyasaka M, Taniguchi T
  Title
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
  Journal
Science 244:551-6 (1989)
DOI:10.1126/science.2785715
  Sequence
[hsa:3560]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Bucheton B, Argiro L, Chevillard C, Marquet S, Kheir MM, Mergani A, El-Safi SH, Dessein AJ
  Title
Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis.
  Journal
Genes Immun 8:79-83 (2007)
DOI:10.1038/sj.gene.6364355
  Sequence
[hsa:3560]
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