KEGG ORTHOLOGY: K05431

ORTHOLOGY: K05431

Entry

K05431                      KO

Symbol

IL7

Name

interleukin 7

Pathway

map04060

Cytokine-cytokine receptor interaction

map04151

PI3K-Akt signaling pathway

map04630

JAK-STAT signaling pathway

map04640

Hematopoietic cell lineage

map05200

Pathways in cancer

Disease

H00842

Epidermodysplasia verruciformis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05431  IL7; interleukin 7
   04151 PI3K-Akt signaling pathway
    K05431  IL7; interleukin 7
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05431  IL7; interleukin 7
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05431  IL7; interleukin 7
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05431  IL7; interleukin 7
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05431  IL7; interleukin 7
   00536 Glycosaminoglycan binding proteins
    K05431  IL7; interleukin 7
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Interleukins
   K05431  IL7; interleukin 7
Glycosaminoglycan binding proteins [BR:ko00536]
Heparan sulfate / Heparin
  Cytokines
   K05431  IL7; interleukin 7

Other DBs

GO:

0005139

Genes

HSA:

3574(IL7)

PTR:	464245(IL7)

PPS:	100986540(IL7)

GGO:	101138372(IL7)

PON:	100447454(IL7)

PPYG:

129042195(IL7)

NLE:	100606680(IL7)

HMH:	116813340(IL7)

SSYN:

129486530(IL7)

MCC:	574168(IL7)

MCF:	102135001(IL7)

MTHB:

126961637

MNI:	105483548(IL7)

CSAB:

103237005(IL7)

CATY:

105572942(IL7)

PANU:

101004703(IL7)

TGE:	112630480(IL7)

MLEU:

105545992(IL7)

RRO:	104665836(IL7)

RBB:	108526207(IL7)

TFN:	117079493(IL7)

PTEH:

111553128(IL7)

CANG:

105508296(IL7)

CJC:	100387798(IL7)

SBQ:	101048813(IL7)

CIMI:

108299533(IL7)

ANAN:

105716324(IL7)

CSYR:

103273840(IL7)

MMUR:

105857580(IL7)

LCAT:

123644763(IL7)

ERUF:

138381800(IL7)

PCOQ:

105825332(IL7)

OGA:	100943181(IL7)

MMU:	16196(Il7)

MCAL:

110290996(Il7)

MPAH:

110321006(Il7)

RNO:	25647(Il7)

MCOC:

116094928(Il7)

ANU:	117719170(Il7)

ASYL:

127683547(Il7)

MUN:	110556314(Il7)

CGE:	100756443(Il7)

MAUA:

110340351(Il7)

PROB:

127231164(Il7)

PLEU:

114707629(Il7)

PMAV:

102914726(Il7)

MORG:

121458462(Il7)

MFOT:

126513375

AAMP:

119826635(Il7)

CNL:	130888015(Il7)

NGI:	103727963(Il7)

HGL:	101713773(Il7)

CPOC:

100725811(Il7)

CCAN:

109698220(Il7)

DORD:

105994808(Il7)

DSP:	122108695(Il7)

DMER:

138805801(Il7)

PLOP:

125360703(Il7)

NCAR:

124983142

MMMA:

107142463(Il7)

ITI:	101968385(Il7)

OCU:

100345409

OPI:	101535938(IL7)

OCZ:	121165420(IL7)

TUP:	102487954(IL7)

GVR:	103593320(IL7)

CFA:	751768(IL7)

CLUD:

112678641(IL7)

VVP:	112930472(IL7)

VLG:	121498816(IL7)

NPO:	129505389(IL7)

AML:	100481194(IL7)

UMR:	103661362(IL7)

UAH:	113253022(IL7)

UAR:	123797942(IL7)

ELK:

111156814

LLV:

125098019

MPUF:

101676635(IL7)

MNP:	132014103(IL7)

MLK:	131826682(IL7)

NVS:	122904498(IL7)

MMAQ:

308341431(IL7)

ORO:	101374293(IL7)

EJU:	114214977(IL7)

ZCA:	113933467(IL7)

MLX:	118014946(IL7)

MANO:

123858958(IL7)

NSU:	110579061(IL7)

LWW:	102729985(IL7)

FCA:	101084597(IL7)

PYU:	121038088(IL7)

PCOO:

112859431(IL7)

PBG:	122495513(IL7)

PVIV:

125156710(IL7)

LRUF:

124507732

LGF:	123586013(IL7)

AJU:

106984935

PTG:	102960296(IL7)

PPAD:

109269381(IL7)

PUC:

125924837

PLEZ:

122211298(IL7)

HHV:	120223141(IL7)

CCRU:

144240264(IL7)

BTA:	280827(IL7)

BOM:	102286767(IL7)

BIU:	109568650(IL7)

BJV:	133260558(IL7)

BBUB:

102393345(IL7)

BKE:	129626836(IL7)

BBIS:

104995049(IL7)

CHX:	102182054(IL7)

OAS:	443341(IL7)

OCAN:

138446224(IL7)

BTAX:

128059511(IL7)

CSUM:

138088645(IL7)

ODA:	120878987(IL7)

CCAD:

122451349(IL7)

MREE:

136144865(IL7)

OVR:	110137603(IL7)

MBEZ:

129560364(IL7)

SSC:	397253(IL7)

CFR:	102504417(IL7)

CBAI:

105066278(IL7)

CDK:	105088534(IL7)

VPC:	102537288(IL7)

BACU:

103000105(IL7)

BMUS:

118883535(IL7)

LVE:	103075444(IL7)

OOR:	101276026(IL7)

LALB:

132508120(IL7)

GMF:	115843286(IL7)

DDP:	132413079(IL7)

SCOO:

307175967(IL7)

PCRS:

137210304(IL7)

DLE:	111164935(IL7)

PCAD:

102976783(IL7)

PSIU:

116742373(IL7)

PPHC:

136136858(IL7)

NASI:

112403878(IL7)

ECB:	100059131(IL7)

EPZ:	103547400(IL7)

EAI:	106839170(IL7)

MYB:	102263096(IL7)

MYD:	102751370(IL7)

MMYO:

118671020(IL7)

MLF:	102418120(IL7)

MDT:	132219918(IL7)

MYUM:

138992948(IL7)

PKL:	118718444(IL7)

EFUS:

103283856(IL7)

MNA:	107539481(IL7)

DRO:	112320869(IL7)

SHON:

118997775(IL7)

AJM:	119052729(IL7)

PDIC:

114501947(IL7)

PHAS:

123825829(IL7)

MMF:	118631690(IL7)

PPAM:

129088356(IL7)

HAI:	109387835(IL7)

RFQ:	117033967(IL7)

RHII:

308506597(IL7)

PALE:

112472586(IL7)

PGIG:

120585527(IL7)

PVP:	105302950(IL7)

MJV:	108398928(IL7)

TOD:	119240528(IL7)

SARA:

101540970(IL7)

SFUM:

130016246(IL7)

SETR:

126020552(IL7)

LAV:	100658284(IL7)

TMU:

101345060

ETF:	101642813(IL7)

DNM:	101423605(IL7)

MDO:	103106447(IL7)

GAS:	123231657(IL7)

SHR:	116420560(IL7)

AFZ:

127546501

PCW:	110199192(IL7)

TVP:	118829859(IL7)

PBRV:

138170676(IL7)

MLAO:

141497270(IL7)

OAA:	114813216(IL7)

TACU:

119945520(IL7)

GGA:	420193(IL7)

CJO:

116652977

APLA:

106015872

AACU:

137851221(IL7)

OJA:

118161398

BCLA:

308441529(IL7)

ACYG:

106030637(IL7)

ABRC:

308189413(IL7)

CATA:

118247918

AFUL:

116485351

TGU:	101234120(IL7)

LSR:	110481797(IL7)

VMC:	128819745(IL7)

VCHA:

128800719(IL7)

AIB:	137471746(IL7)

SCAN:

103816360(IL7)

PMOA:

120499321(IL7)

OTC:	121340187(IL7)

PRUF:

121351959(IL7)

ATRC:

139587248(IL7)

MATE:

118699934(IL7)

MAEN:

136554924(IL7)

OMA:	130249898(IL7)

PHI:	102102794(IL7)

PMAJ:

107200924(IL7)

CCW:	120409642(IL7)

CBRC:

103619872

ACOE:

138105234(IL7)

ETL:	114058655(IL7)

ZAB:	106629757(IL7)

ZLE:

135443347

ACHL:

103810074

SVG:	106849836(IL7)

MMEA:

130584383(IL7)

SATI:

136369646(IL7)

CFAI:

136287258(IL7)

SHAB:

115616408(IL7)

POCC:

134175505(IL7)

FCH:

114017616

FRS:	119145431(IL7)

CCRI:

104156586

ACUN:

113476147

ANOC:

141957388(IL7)

SURA:

141949557(IL7)

TALA:

116965317(IL7)

ACHC:

115340800(IL7)

HALD:

104316015

HLE:

104837056

AGEN:

126048479

HHAR:

128142409(IL7)

BBUT:

142029131(IL7)

GCL:

CSTI:

LDI:

MNB:

DPUB:

AVIT:

EGZ:

PCRI:

PCAO:

PARX:

142053510(IL7)

PADL:

103926225

AFOR:

103893328

FGA:

104080603

CBOR:

142078691(IL7)

GSTE:

104252592

CBOY:

140646882(IL7)

MAME:

142406800(IL7)

CNIC:

135986136(IL7)

NMAY:

308053266(IL7)

MUI:

104535323

PGUU:

104465242

CUCA:

104068116(IL7)

PCUR:

138718620(IL7)

TEO:

104374909

GAME:

129203645(IL7)

OHA:

ACAR:

CPEA:

CVF:

RTD:	128906373(IL7)

CRID:

134512067(IL7)

LMIC:

141739634(IL7)

NARQ:

141464088(IL7)

AAM:

106484576

AROW:

112974010(IL7)

TGT:

104574704

DNE:

112988716

SCAM:

104153524

PSS:	102452006(IL7)

CIZ:

142008519

CMY:	102945832(IL7)

CCAY:

125632580(IL7)

LKP:	140906587(IL7)

NDS:	141981359(IL7)

DCC:	119850846(IL7)

CPIC:

101942941(IL7)

TST:	117873599(IL7)

CABI:

116838149(IL7)

MRV:	120399626(IL7)

EMQ:	137156802(IL7)

ACS:

103278502

PGUT:

117672910

APRI:

131194149(IL7)

PTEX:

113439959(IL7)

NSS:	113428936(IL7)

STOW:

125438807(IL7)

EMC:	129333142(IL7)

PWL:	138282611(IL7)

MUO:	115478443(IL7)

GSH:	117355157(IL7)

ARUT:

117435586

LCM:	102353780(IL7)

RTP:

CPLA:

HOC:

HAKA:

NVE:

Reference

PMID:21889323

Authors

Liao W, Lin JX, Leonard WJ

Title

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation.

Journal

Curr Opin Immunol 23:598-604 (2011)
DOI:10.1016/j.coi.2011.08.003

Reference

PMID:2643102

Authors

Goodwin RG, Lupton S, Schmierer A, Hjerrild KJ, Jerzy R, Clevenger W, Gillis S, Cosman D, Namen AE

Title

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

Journal

Proc Natl Acad Sci U S A 86:302-6 (1989)
DOI:10.1073/pnas.86.1.302

Sequence

[hsa:3574]

LinkDB

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