KEGG   ORTHOLOGY: K05827
Entry
K05827                      KO                                     
Symbol
lysX
Name
[lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
Pathway
map00300  Lysine biosynthesis
map01100  Metabolic pathways
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
Reaction
R09775  LysW:L-2-aminoadipate ligase (ADP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05827  lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.43  [amino-group carrier protein]---L-2-aminoadipate ligase
     K05827  lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase
Other DBs
COG: COG0189
Genes
ENF: AKI40_3663(rimK)
SERA: Ser39006_009290
SERQ: CWC46_09285
CARI: FNU76_03420
MSD: MYSTI_01368
MFB: MFUL124B02_07595
MLAN: JY572_19520
CCX: COCOR_02065(lysX)
PPAK: JY651_31930
AVM: JQX13_36445
SAUC: CA347_99
PMW: B2K_22490
PSWU: SY83_08915
SGR: SGR_3478
SFI: SFUL_3350
SFA: Sfla_0121
STRP: F750_6903(lysX)
SPRI: SPRI_3646
SRW: TUE45_06896(lysX_3)
SLAU: SLA_3045
SALJ: SMD11_6708(lysX)
SCYG: S1361_31450(lysX4)
STPB: QR97_19335
ACIR: OG979_26760(lysX)
SESP: BN6_56710
SSYI: EKG83_30610(lysX)
ASE: ACPL_7493(rimK)
ACTS: ACWT_7363
DAUR: Daura_16095(lysX)
CAI: Caci_6289
RCA: Rcas_3469
CAU: Caur_0334
CAG: Cagg_3597
HAU: Haur_3306
ATM: ANT_08250(lysX) ANT_12410(lysX)
CAP: CLDAP_04850(lysX)
KBS: EPA93_38760(lysX)
THUG: KNN16_06510(lysX)
PMET: G4Y79_18395(lysX)
TRO: trd_1519(lysX) trd_A0165(lysX)
DRA: DR_2194
DGE: Dgeo_1151
DEZ: DKM44_08535(lysX)
DWU: DVJ83_00355(lysX)
DFC: DFI_07055
DEIN: DAAJ005_09940(lysX)
DPH: EHF33_03465(lysX)
DRB: N0D28_11275(lysX)
DAQU: M8445_12315(lysX)
DTAE: LAJ19_06370(lysX)
DMB: E5F05_13845(lysX)
DSC: ABOD76_16805(lysX)
TRA: Trad_1392
TTH: TT_C1543
TTJ: TTHA1907(TTHA1907)
TSC: TSC_c01920(lysX)
TAQ: TO73_0098
TANT: KNN15_05130(lysX)
MRB: Mrub_2724
SCOR: J3U87_02875(lysX)
TAI: Taci_0444
TLI: Tlie_1469
ARAM: KAR29_00420(lysX)
MRO: MROS_0165
CABY: Cabys_3148
PFU: PF0209
PFI: PFC_00105
PYS: Py04_0364
PTO: PTO1469
FAI: FAD_0508(lysX)
CDIV: CPM_0545
APE: APE_1463(lysX)
ACJ: ACAM_0923(lysX)
IHO: Igni_0057
IIS: EYM_02245
IPC: IPA_00760
IAG: Igag_1752
PABI: PABY_17850(lysX_2)
PARE: PYJP_07930(lysX_2)
STO: STK_01920(lysX)
SOH: D1869_00430(lysX)
SSO: SSO0159(rimK-1)
SOL: Ssol_1137
SSOA: SULA_1173(lysX)
SSOL: SULB_1174(lysX)
SSOF: SULC_1172(lysX)
SCAS: SACC_00720
SAI: Saci_0754
SID: M164_1986
SII: LD85_2241
SIH: SiH_1924
SIR: SiRe_1851
SIC: SiL_1833
SULE: GFS03_10845(lysX)
SULO: GFS33_02660(lysX)
SULL: EWF20_01870(lysX)
MSE: Msed_0168
MEMJ: MJ1HA_0247
MCN: Mcup_1905
MHK: DFR87_05970(lysX)
MPRU: DFR88_05800(lysX)
MTEN: GWK48_06250(lysX)
AHO: Ahos_0887
ABRI: DFR85_06560(lysX)
ASUL: DFR86_07300(lysX)
AAMB: D1866_12330(lysX)
ACIH: HS5_22620
SAZO: D1868_01575(lysX)
CSTY: KN1_18130
STEP: IC006_1906
SMET: RQ359_002317(lysX)
PAI: PAE1240
PIS: Pisl_1291
PCL: Pcal_1379
PAS: Pars_0291
PYR: P186_2608
POG: Pogu_2164
TNE: Tneu_0259
CMA: Cmaq_1298
TTN: TTX_0466(lysX_rimK)
TUZ: TUZN_0807
VDI: Vdis_0200
VMO: VMUT_1538
KCR: Kcr_0812
NIW: Nisw_07255(lysX) Nisw_07290(lysX)
NCL: C5F47_06940(lysX) C5F47_06975(lysX)
NOX: C5F49_06950(lysX) C5F49_06985(lysX)
NUE: C5F50_09705(lysX) C5F50_09740(lysX)
NIP: NsoK4_01565(lysX) NsoK4_01595(lysX)
NCT: NMSP_0393(lysX_1) NMSP_0403(lysX_2)
NIC: DSQ20_07905(lysX) DSQ20_07940(lysX)
NGA: Ngar_c14560(lysX1) Ngar_c29970(lysX2)
NVN: NVIE_002660(lysX1) NVIE_016500(lysX2)
TAA: NMY3_02221(lysX_1) NMY3_02228(lysX_2)
NFN: NFRAN_2983(lysX) NFRAN_2990(lysX)
NCV: NCAV_1252(lysX) NCAV_1409(lysX)
NBV: T478_1043(lysX) T478_1050(lysX)
NIU: DSQ19_03190(lysX) DSQ19_03225(lysX)
NDV: NDEV_1623(lysX) NDEV_1630(lysX)
 » show all
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
  Sequence
[tth:TT_C1543]
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0754]
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