KEGG   REACTION: R09775
Entry
R09775                      Reaction                               
Name
LysW:L-2-aminoadipate ligase (ADP-forming);
[lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate:L-2-aminoadipate ligase (ADP-forming)
Definition
L-2-Aminoadipate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-gamma-L-alpha-aminoadipate + ADP + Orthophosphate
Equation
Reaction class
RC00002  C00002_C00008
RC00064  C00956_C19886
RC00090  C19885_C19886
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.43
     R09775  L-2-Aminoadipate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-gamma-L-alpha-aminoadipate + ADP + Orthophosphate
Orthology
K05827  [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
K25032  alpha-aminoadipate-LysW ligase/glutamate-LysW ligase [EC:6.3.2.43 6.3.2.60]
Other DBs
RHEA: 41943
LinkDB

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