KEGG   ORTHOLOGY: K07191
Entry
K07191                      KO                                     
Symbol
SLC2A4, GLUT4
Name
MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
Pathway
map04068  FoxO signaling pathway
map04152  AMPK signaling pathway
map04910  Insulin signaling pathway
map04920  Adipocytokine signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
   04152 AMPK signaling pathway
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
   04920 Adipocytokine signaling pathway
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
   04931 Insulin resistance
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC2: Facilitative GLUT transporter
   K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
 Major facilitator superfamily (MFS)
  Sugar transporters
   Sugar porter (SP) family
    K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
Other DBs
GO: 0005355
TC: 2.A.1.1
Genes
HSA: 6517(SLC2A4)
PTR: 468443(SLC2A4)
PPS: 100985502(SLC2A4)
GGO: 101147700(SLC2A4)
PON: 100456448(SLC2A4)
PPYG: 129017782(SLC2A4)
NLE: 100587831(SLC2A4)
HMH: 116459323(SLC2A4)
SSYN: 129470132(SLC2A4)
MCC: 714701(SLC2A4)
MCF: 102114914(SLC2A4)
MTHB: 126939701
MNI: 105473329(SLC2A4)
CSAB: 103242286(SLC2A4)
CATY: 105582615(SLC2A4)
PANU: 101021830(SLC2A4)
TGE: 112609908(SLC2A4)
MLEU: 105549897(SLC2A4)
RRO: 104673327(SLC2A4)
RBB: 108514300(SLC2A4)
TFN: 117067797(SLC2A4)
PTEH: 111521329(SLC2A4)
CANG: 105523598(SLC2A4)
CJC: 100396530(SLC2A4)
SBQ: 101032629(SLC2A4)
CIMI: 108306596(SLC2A4)
ANAN: 105720778(SLC2A4)
CSYR: 103263229(SLC2A4)
MMUR: 105877856(SLC2A4)
LCAT: 123650860(SLC2A4)
PCOQ: 105819426(SLC2A4)
OGA: 100945996(SLC2A4)
MMU: 20528(Slc2a4)
MCAL: 110304808(Slc2a4)
MPAH: 110331375(Slc2a4)
RNO: 25139(Slc2a4)
MCOC: 116079077(Slc2a4)
ANU: 117711148(Slc2a4)
MUN: 110555123(Slc2a4)
CGE: 100766656(Slc2a4)
MAUA: 101827218(Slc2a4)
PROB: 127219033(Slc2a4)
PLEU: 114693201(Slc2a4)
MORG: 121456757(Slc2a4)
MFOT: 126514088
AAMP: 119812189(Slc2a4)
NGI: 103752150(Slc2a4)
HGL: 101714675(Slc2a4)
CPOC: 100716624(Slc2a4)
CCAN: 109674563(Slc2a4)
DORD: 105983532(Slc2a4)
DSP: 122100445(Slc2a4)
PLOP: 125365553(Slc2a4)
NCAR: 124980544
MMMA: 107157976(Slc2a4)
OCU: 100037710(SLC2A4)
OPI: 101535491(SLC2A4)
TUP: 102483507(SLC2A4)
GVR: 103591431(SLC2A4)
CFA: 403673(SLC2A4)
CLUD: 112647488(SLC2A4)
VVP: 112924825(SLC2A4)
VLG: 121500373(SLC2A4)
NPO: 129497652(SLC2A4)
AML: 100473294(SLC2A4)
UMR: 103660467(SLC2A4)
UAH: 113271115(SLC2A4)
UAR: 123792161(SLC2A4)
ELK: 111161132
LLV: 125086801
MPUF: 101673972(SLC2A4)
MNP: 132003514(SLC2A4)
MLK: 131816528(SLC2A4)
NVS: 122906692(SLC2A4)
ORO: 101373530(SLC2A4)
EJU: 114225368(SLC2A4)
ZCA: 113939593(SLC2A4)
MLX: 118000005(SLC2A4)
NSU: 110584441(SLC2A4)
LWW: 102734794(SLC2A4)
FCA: 101095139(SLC2A4)
PYU: 121016014(SLC2A4)
PBG: 122484862(SLC2A4)
PVIV: 125152069(SLC2A4)
LRUF: 124519562
PTG: 102966593(SLC2A4)
PPAD: 109245971(SLC2A4)
PUC: 125926175
AJU: 106972419
HHV: 120231407(SLC2A4)
BTA: 282359(SLC2A4)
BOM: 102272151(SLC2A4)
BIU: 109574066(SLC2A4)
BBUB: 102410502(SLC2A4)
BBIS: 104993926(SLC2A4)
CHX: 102183003(SLC2A4)
OAS: 101118797(SLC2A4)
BTAX: 128065241(SLC2A4)
ODA: 120866070(SLC2A4)
CCAD: 122446129(SLC2A4)
MBEZ: 129542678(SLC2A4)
SSC: 396754(SLC2A4)
CFR: 102517742(SLC2A4)
CBAI: 105077487(SLC2A4)
CDK: 105103041(SLC2A4)
VPC: 102536880(SLC2A4)
BACU: 102998831(SLC2A4)
BMUS: 118886981(SLC2A4)
LVE: 103080308(SLC2A4)
OOR: 101273257(SLC2A4)
DLE: 111185702(SLC2A4)
PCAD: 102996407(SLC2A4)
PSIU: 116746346(SLC2A4)
NASI: 112390428(SLC2A4)
ECB: 100033939(SLC2A4)
EPZ: 103557737(SLC2A4)
EAI: 106844181(SLC2A4)
MYB: 102238939(SLC2A4)
MYD: 102751885(SLC2A4)
MMYO: 118672052(SLC2A4)
MLF: 102419367(SLC2A4)
MDT: 132218091(SLC2A4)
PKL: 118726811(SLC2A4)
EFUS: 103296925(SLC2A4)
MNA: 107544606(SLC2A4)
DRO: 112308641(SLC2A4)
SHON: 118974635(SLC2A4)
AJM: 119037164(SLC2A4)
PDIC: 114514995(SLC2A4)
PHAS: 123809243(SLC2A4)
MMF: 118634418(SLC2A4)
PPAM: 129072310(SLC2A4)
HAI: 109394684(SLC2A4)
RFQ: 117013528(SLC2A4)
PALE: 102881931(SLC2A4)
PGIG: 120589639(SLC2A4)
PVP: 105291195(SLC2A4)
RAY: 107509522(SLC2A4)
MJV: 108406495(SLC2A4)
TOD: 119232046(SLC2A4)
SARA: 101542477(SLC2A4)
SETR: 125997945(SLC2A4)
LAV: 100658880(SLC2A4)
TMU: 101358486
ETF: 101659665(SLC2A4)
DNM: 101412620(SLC2A4)
MDO: 100015271(SLC2A4)
GAS: 123244446(SLC2A4)
SHR: 100929154(SLC2A4)
AFZ: 127560904
PCW: 110194311(SLC2A4)
TVP: 118858260(SLC2A4)
OAA: 100091317(SLC2A4)
MGP: 104916152
CJO: 107306987
LSR: 110474551
OMA: 130262755
PHI: 102109274
ETL: 114071965
ZLE: 135460682
ASN: 102370597(SLC2A4)
AMJ: 102567880(SLC2A4)
PSS: 102445527(SLC2A4)
CMY: 102935953(SLC2A4)
CCAY: 125628638(SLC2A4)
DCC: 119849329(SLC2A4)
CPIC: 101947700(SLC2A4)
TST: 117869961
CABI: 116833180(SLC2A4)
MRV: 120381851(SLC2A4)
ACS: 100566978(slc2a4)
ASAO: 132777535(SLC2A4)
PVT: 110082351(SLC2A4)
SUND: 121934649(SLC2A4)
PBI: 103064493(SLC2A4)
PMUR: 107298863(SLC2A4)
CTIG: 120305699(SLC2A4)
TSR: 106553883(SLC2A4)
PGUT: 117658323(SLC2A4)
APRI: 131198462(SLC2A4)
PTEX: 113453031
NSS: 113428857
VKO: 123016664(SLC2A4)
PMUA: 114608086(SLC2A4)
PRAF: 128399319(SLC2A4)
ZVI: 118094775(SLC2A4)
HCG: 128330332(SLC2A4)
GJA: 107118105(SLC2A4)
STOW: 125445158(SLC2A4)
EMC: 129340375(SLC2A4)
XLA: 444033(slc2a4.L)
XTR: 101731550(slc2a4)
NPR: 108803584(SLC2A4)
RTEM: 120921692(SLC2A4)
BBUF: 120986724(SLC2A4)
BGAR: 122926263(SLC2A4)
MUO: 115457634(SLC2A4)
GSH: 117350777(SLC2A4)
SRX: 107757841(slc2a4)
SANH: 107675145(slc2a4)
SGH: 107565717(slc2a4)
CAUA: 113098888(slc2a4)
CGIB: 128017690
PTET: 122348704
LROH: 127160655
OMC: 131543329
PPRM: 120477875
RKG: 130076854
MAMB: 125265600
CIDE: 127516638
CERY: 137031135
TROS: 130554156
TDW: 130424428
MANU: 129449401
IPU: 108267905
IFU: 128609970
PHYP: 113540575(slc2a4)
SMEO: 124386842
TFD: 113657537
TVC: 132848541
TRN: 134311906
AMEX: 103037103
CMAO: 118825642
EEE: 113577323(slc2a4)
CHAR: 105907174
TRU: 101066876(slc2a4)
TFS: 130522831
LCO: 104923961(slc2a4)
NCC: 104945429(slc2a4)
TBEN: 117488170
CGOB: 115023591(slc2a4)
PGEO: 117463626
GACU: 117552766
EMAC: 134875881
ELY: 117246042
EFO: 125883674
SLUC: 116049033
ECRA: 117962209
ESP: 116686371(slc2a4)
PFLV: 114545717(slc2a4)
GAT: 120821890
PPUG: 119222591
AFB: 129093077
CLUM: 117747866
PSWI: 130211711
MSAM: 119912349
SCHU: 122870058
CUD: 121504589
ALAT: 119027789
ASTR: 137590811
MZE: 101480176(slc2a4)
ONL: 100699345(slc2a4)
OAU: 116310387
OLA: 101158976(slc2a4)
OML: 112155675
CSAI: 133420064
XMA: 102227271(slc2a4)
XCO: 114157716(slc2a4)
XHE: 116732252(slc2a4)
PRET: 103480459(slc2a4)
PFOR: 103137499(slc2a4)
PLAI: 106945772(slc2a4)
PMEI: 106919125(slc2a4)
GAF: 122819960
PPRL: 129354901
CVG: 107087738(slc2a4)
CTUL: 119783435
GMU: 124880686
NFU: 107377390(slc2a4)
KMR: 108251468
ALIM: 106525322(slc2a4)
NWH: 119409395
AOCE: 111577182(slc2a4)
MCEP: 125019514
CSEM: 103387221(slc2a4)
POV: 109634843(slc2a4)
SSEN: 122767328
HHIP: 117752058
HSP: 118102310
PPLT: 128429802
SMAU: 118320596
LCF: 108879977
SDU: 111232998(slc2a4)
SLAL: 111650692(slc2a4)
XGL: 120797611
HCQ: 109520370(slc2a4)
SSCV: 125992377
SBIA: 133494678
PEE: 133397664
PTAO: 133472381
BPEC: 110159470(slc2a4)
MALB: 109951397(slc2a4)
BSPL: 114843113
SJO: 128383862
STRU: 115194177 115198178(slc2a4)
ELS: 105020675(slc2a4)
SFM: 108923140(slc2a4)
PKI: 111854450(slc2a4)
AANG: 118222920
LOC: 102682554(slc2a4)
PSEX: 120525034
LCM: 102365328(SLC2A4)
RTP: 109924526
HOC: 132835334
LERI: 129715703
 » show all
Reference
PMID:2649253
  Authors
Birnbaum MJ
  Title
Identification of a novel gene encoding an insulin-responsive glucose transporter protein.
  Journal
Cell 57:305-15 (1989)
DOI:10.1016/0092-8674(89)90968-9
  Sequence
[rno:25139]
Reference
  Authors
Zhao FQ, Keating AF
  Title
Functional properties and genomics of glucose transporters.
  Journal
Curr Genomics 8:113-28 (2007)
DOI:10.2174/138920207780368187
Reference
  Authors
Wood IS, Trayhurn P
  Title
Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.
  Journal
Br J Nutr 89:3-9 (2003)
DOI:10.1079/BJN2002763
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