KEGG   ORTHOLOGY: K07249
Entry
K07249                      KO                                     

Symbol
ALDH1A
Name
retinal dehydrogenase [EC:1.2.1.36]
Pathway
map00830  Retinol metabolism
map01100  Metabolic pathways
Disease
H01027  Microphthalmia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07249  ALDH1A; retinal dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.36  retinal dehydrogenase
     K07249  ALDH1A; retinal dehydrogenase
Other DBs
RN: R02123 R08385
GO: 0001758
Genes
HSA: 216(ALDH1A1) 220(ALDH1A3) 8854(ALDH1A2)
PTR: 453686(ALDH1A3) 464529(ALDH1A1) 746847(ALDH1A2)
PPS: 100967518(ALDH1A3) 100976079(ALDH1A2) 100994654(ALDH1A1)
GGO: 101135029(ALDH1A3) 101135810(ALDH1A1) 101139899(ALDH1A2)
PON: 100174688(ALDH1A1) 100452276(ALDH1A3)
NLE: 100584839(ALDH1A1) 100586116(ALDH1A3) 100604565(ALDH1A2)
MCC: 694231(ALDH1A3) 702235(ALDH1A2) 702598(ALDH1A1)
MCF: 101865761(ALDH1A1) 102115665(ALDH1A3) 102120533(ALDH1A2)
CSAB: 103219585(ALDH1A1) 103231285(ALDH1A3) 103245564(ALDH1A2)
CATY: 105584180(ALDH1A1) 105593981(ALDH1A3) 105601098(ALDH1A2)
RRO: 104670902(ALDH1A2) 104672127(ALDH1A1) 104676802(ALDH1A3)
RBB: 108517690(ALDH1A1) 108522929(ALDH1A3) 108545023(ALDH1A2)
TFN: 117070124(ALDH1A3) 117070593(ALDH1A2) 117098468(ALDH1A1)
PTEH: 111527337(ALDH1A3) 111543351(ALDH1A1) 111553680(ALDH1A2)
CJC: 100397394(ALDH1A3) 100407242(ALDH1A1) 100413342(ALDH1A2)
SBQ: 101036566(ALDH1A1) 101040576(ALDH1A2) 101054138(ALDH1A3)
MMU: 11668(Aldh1a1) 19378(Aldh1a2) 26358(Aldh1a7) 56847(Aldh1a3)
MCAL: 110285566 110286084 110297746(Aldh1a3) 110301178(Aldh1a2)
MPAH: 110316784(Aldh1a3) 110318664 110321962 110327235(Aldh1a2)
RNO: 116676(Aldh1a2) 24188(Aldh1a1) 266603(Aldh1a3) 29651(Aldh1a7)
MCOC: 116072970(Aldh1a2) 116102356(Aldh1a3) 116103646 116103650
MUN: 110539716(Aldh1a1) 110539717 110546444(Aldh1a3) 110563079(Aldh1a2)
PLEU: 114690728(Aldh1a2) 114695478(Aldh1a3) 114709799(Aldh1a1) 114709824 114709833
NGI: 103737699 103737700(Aldh1a1) 103745514(Aldh1a2) 103747192(Aldh1a3)
HGL: 101696832 101697212 101699741(Aldh1a2) 101700669(Aldh1a3) 101705109 101706446(Aldh1a1)
OCU: 100008636(ALDH1A1) 100339014(ALDH1A2) 100356011(ALDH1A3)
OPI: 101530793(ALDH1A1) 101531551(ALDH1A2) 101532963(ALDH1A3)
TUP: 102471053(ALDH1A2) 102479319(ALDH1A1) 102491549(ALDH1A3)
CFA: 100856346(ALDH1A3) 476323(ALDH1A1) 478319(ALDH1A2)
VVP: 112920507(ALDH1A2) 112922104(ALDH1A1) 112922339(ALDH1A3)
VLG: 121485029(ALDH1A1) 121485596(ALDH1A2) 121489866(ALDH1A3)
AML: 100467752(ALDH1A3) 100468591(ALDH1A2)
UMR: 103660039(ALDH1A3) 103663346(ALDH1A1) 103663347 103676790(ALDH1A2)
UAH: 113263632(ALDH1A3) 113269676(ALDH1A2) 113269854(ALDH1A1)
ORO: 101376607(ALDH1A1) 101379244(ALDH1A2) 101381188(ALDH1A3)
MPUF: 101674037(ALDH1A2) 101679832(ALDH1A1) 101690008(ALDH1A3)
EJU: 114197898(ALDH1A1) 114206505(ALDH1A2) 114223808(ALDH1A3)
MLX: 118003320(ALDH1A2) 118022990(ALDH1A3) 118026291(ALDH1A1)
FCA: 101081050(ALDH1A3) 101082916(ALDH1A2) 101090397(ALDH1A1)
PYU: 121013631(ALDH1A1) 121041766(ALDH1A2) 121042494(ALDH1A3)
PBG: 122468306(ALDH1A3) 122468589(ALDH1A2) 122475460(ALDH1A1)
PTG: 102949007(ALDH1A2) 102949855(ALDH1A1) 102952022(ALDH1A3)
PPAD: 109262922(ALDH1A2) 109273343(ALDH1A3) 109275394(ALDH1A1)
AJU: 106967069(ALDH1A1) 106972083(ALDH1A3) 106973786(ALDH1A2)
HHV: 120230876(ALDH1A2) 120233703(ALDH1A3) 120238019(ALDH1A1)
BTA: 281615(ALDH1A1) 507093(ALDH1A3) 535075(ALDH1A2)
BOM: 102271327(ALDH1A2) 102280344(ALDH1A1) 102284286(ALDH1A3)
BIU: 109562959(ALDH1A1) 109575619(ALDH1A3)
BBUB: 102394840(ALDH1A3) 102397240(ALDH1A1) 102410138(ALDH1A2)
CHX: 102171605(ALDH1A1) 102179885(ALDH1A3) 102181689(ALDH1A2)
OAS: 101109831(ALDH1A3) 101117509(ALDH1A2) 443343(ALDH1A1)
ODA: 120853039(ALDH1A2) 120873445(ALDH1A1) 120875269(ALDH1A3)
CCAD: 122443555(ALDH1A2) 122453367(ALDH1A1) 122455277(ALDH1A3)
SSC: 100517137(ALDH1A1) 100737077(ALDH1A2) 102162530(ALDH1A3)
CFR: 102504927(ALDH1A3) 102516021(ALDH1A2) 102517350(ALDH1A1) 102521572
CBAI: 105067277(ALDH1A1) 105075150(ALDH1A3) 105080463(ALDH1A2) 105083513
CDK: 105088595 105088658(ALDH1A2) 105093453(ALDH1A3) 105106124(ALDH1A1)
BACU: 103001749(ALDH1A1) 103008947(ALDH1A2) 103013550(ALDH1A3)
LVE: 103073135(ALDH1A2) 103082981(ALDH1A3) 103085237(ALDH1A1)
OOR: 101271446(ALDH1A1) 101274847(ALDH1A2) 101279390(ALDH1A3)
DLE: 111174597(ALDH1A1) 111177659(ALDH1A2) 111187345(ALDH1A3)
PCAD: 102978495(ALDH1A2) 102987484(ALDH1A1) 102991584(ALDH1A3)
ECB: 100054550(ALDH1A2) 100054931(ALDH1A1) 100057072(ALDH1A3)
EPZ: 103552036(ALDH1A2) 103557113(ALDH1A3) 103565224(ALDH1A1)
EAI: 106830048(ALDH1A2) 106836116(ALDH1A1) 106839471(ALDH1A3)
MYB: 102241863(ALDH1A3) 102245019(ALDH1A2) 102252022(ALDH1A1)
MYD: 102755098(ALDH1A2) 102758582(ALDH1A3) 102769215(ALDH1A1)
MMYO: 118652741(ALDH1A2) 118667457(ALDH1A1) 118679269(ALDH1A3)
MNA: 107527999(ALDH1A3) 107532323(ALDH1A1) 107533749(ALDH1A2)
PKL: 118716486(ALDH1A1) 118720602(ALDH1A2)
HAI: 109380344(ALDH1A3) 109387016(ALDH1A1) 109390699(ALDH1A2)
DRO: 112300261(ALDH1A1) 112305956(ALDH1A3) 112311378(ALDH1A2)
SHON: 118992025(ALDH1A3) 118992256(ALDH1A2) 118997813(ALDH1A1)
AJM: 119045588(ALDH1A1) 119049791(ALDH1A3) 119053478(ALDH1A2)
MMF: 118629448(ALDH1A2) 118629787(ALDH1A1) 118640852(ALDH1A3)
PALE: 102889864(ALDH1A3) 102895099(ALDH1A1) 102896470(ALDH1A2)
PGIG: 120585460(ALDH1A1) 120587354(ALDH1A3) 120604591(ALDH1A2)
RAY: 107511645(ALDH1A1) 107515787(ALDH1A3) 107518612(ALDH1A2)
MJV: 108391415(ALDH1A2) 108405240(ALDH1A1)
TOD: 119231244(ALDH1A1) 119238668(ALDH1A2) 119244337(ALDH1A3)
MDO: 100019941(ALDH1A2) 100020742(ALDH1A1) 100020791(ALDH1A4) 100020853(ALDH1A5) 100020879(ALDH1A6) 100616732(ALDH1A3)
OAA: 100074461(ALDH1A1) 100083368(ALDH1A3) 100093567(ALDH1A2)
GGA: 395264(ALDH1A1) 395389(ALDH1A3) 395844(ALDH1A2)
PCOC: 116225439(ALDH1A3) 116238858(ALDH1A1) 116244655(ALDH1A2)
MGP: 100545801(ALDH1A2) 100546607(ALDH1A3) 104915075
CJO: 107306209(ALDH1A1) 107318519(ALDH1A2) 107318982(ALDH1A3)
NMEL: 110390028(ALDH1A1) 110403577(ALDH1A3) 110403626(ALDH1A2)
APLA: 101793139(ALDH1A3) 101801759(ALDH1A2) 101802481(ALDH1A1)
ACYG: 106033699(ALDH1A2) 106036495(ALDH1A3) 106044484(ALDH1A1)
TGU: 100223406(ALDH1A1) 100231202(ALDH1A3) 751771(ALDH1A2)
LSR: 110471422(ALDH1A2) 110476505(ALDH1A1) 110482959(ALDH1A3)
SCAN: 103815983(ALDH1A2) 103816096(ALDH1A3) 103822878
PMOA: 120507136(ALDH1A1) 120508986(ALDH1A2) 120509067(ALDH1A3)
OTC: 121343425(ALDH1A2) 121343543(ALDH1A3) 121345373(ALDH1A1)
PRUF: 121348658(ALDH1A1) 121354455(ALDH1A2) 121354475(ALDH1A3)
GFR: 102037159(ALDH1A3) 102043395(ALDH1A2) 102043637(ALDH1A1)
FAB: 101812539(ALDH1A1) 101813835(ALDH1A2) 101816772(ALDH1A3)
PHI: 102103267(ALDH1A1) 102105549(ALDH1A3) 102111147(ALDH1A2)
PMAJ: 107209234(ALDH1A2) 107209559(ALDH1A3) 107215910(ALDH1A1)
CCAE: 111933997(ALDH1A3) 111934165(ALDH1A2) 111941552(ALDH1A1)
CCW: 104683830(ALDH1A2) 104683903(ALDH1A3) 104685243(ALDH1A1)
ETL: 114055250(ALDH1A3) 114056360(ALDH1A2) 114056667(ALDH1A1)
FPG: 101914714(ALDH1A1) 101915870(ALDH1A3) 101919921(ALDH1A2)
FCH: 102048413(ALDH1A1) 102050613(ALDH1A3) 102051355(ALDH1A2)
CLV: 102086687(ALDH1A2) 102089147(ALDH1A3) 102091373(ALDH1A1)
EGZ: 104122868(ALDH1A3) 104123840(ALDH1A1) 104130885(ALDH1A2)
NNI: 104016850 104017064(ALDH1A3) 104017279 104020883(ALDH1A1)
ACUN: 113483899(ALDH1A3) 113484203(ALDH1A2) 113489966(ALDH1A1)
PADL: 103914768(ALDH1A3) 103914861(ALDH1A2) 103920375(ALDH1A1)
AAM: 106490505 106495827(ALDH1A3) 106496536(ALDH1A2)
AROW: 112963646(ALDH1A2) 112965236(ALDH1A1) 112970104(ALDH1A3)
NPD: 112944392(ALDH1A1) 112948314(ALDH1A3) 112952787(ALDH1A2)
DNE: 112981888(ALDH1A1) 112991112(ALDH1A2) 112996312(ALDH1A3)
ASN: 102368111(ALDH1A3) 102376803(ALDH1A2) 102378695(ALDH1A1)
AMJ: 102558250(ALDH1A2) 102571914(ALDH1A1) 102573093(ALDH1A3)
CPOO: 109308980(ALDH1A2) 109309164(ALDH1A3) 109323434(ALDH1A1)
GGN: 109288461(ALDH1A3) 109288644(ALDH1A2) 109297589(ALDH1A1)
PSS: 102446643(ALDH1A2) 102450892(ALDH1A3) 102453636(ALDH1A1)
CMY: 102939103(ALDH1A3) 102943259(ALDH1A2) 102943361(ALDH1A1)
CPIC: 101933340(ALDH1A1) 101943620(ALDH1A2) 101946404(ALDH1A3)
TST: 117875210 117878955(ALDH1A1) 117883790(ALDH1A2)
CABI: 116816661(ALDH1A3) 116821166(ALDH1A2) 116835367(ALDH1A1)
ACS: 100555228(aldh1a3) 100556217(aldh1a2) 100566345(aldh1a1)
PVT: 110072975(ALDH1A3) 110074545(ALDH1A2) 110081706 110081707
PBI: 103055946(ALDH1A2) 103056376(ALDH1A3) 103057171(ALDH1A1)
PMUR: 107283177(ALDH1A2) 107283882(ALDH1A3) 107288134(ALDH1A1)
TSR: 106542885(ALDH1A2) 106545343(ALDH1A1)
PGUT: 117660953(ALDH1A2) 117661441(ALDH1A1) 117669868(ALDH1A3)
PMUA: 114584290(ALDH1A2) 114584458(ALDH1A3) 114606374(ALDH1A1)
ZVI: 118076796(ALDH1A1) 118093058(ALDH1A2) 118093098(ALDH1A3)
GJA: 107108680(ALDH1A2) 107111752(ALDH1A1) 107116104(ALDH1A3)
XLA: 108712817(aldh1a3.S) 108712938(aldh1a2.S) 394296(aldh1a1.S) 397728(aldh1a1.L) 399389(aldh1a2.L) 733178(aldh1a3.L)
XTR: 100485844(aldh1a3) 613078(aldh1a1) 734052(aldh1a2)
NPR: 108789830(ALDH1A2) 108790072(ALDH1A3) 108791719(ALDH1A1)
DRE: 116713(aldh1a2) 751785(aldh1a3)
IPU: 108259626(aldh1a2) 108271441(aldh1a3)
PHYP: 113536398(aldh1a3) 113540928(aldh1a2)
AMEX: 103032207(aldh1a3) 103042804(aldh1a2)
EEE: 113573937(aldh1a3) 113575738(aldh1a2)
TRU: 100294697(raldh3) 115246414(aldh1a3) 613232(aldh1a2)
LCO: 104924302(aldh1a2) 104929720(aldh1a3)
NCC: 104960054(aldh1a2) 104961728
CGOB: 115004864(aldh1a3) 115013264(aldh1a1) 115025071(aldh1a2)
ELY: 117252033 117255575(aldh1a2) 117266244(aldh1a3)
PLEP: 121942467(aldh1a3) 121944054 121947788(aldh1a2)
SLUC: 116045174(aldh1a3) 116060588(aldh1a2)
ECRA: 117945336(aldh1a2) 117947487(aldh1a3)
PFLV: 114558146(aldh1a3) 114564945(aldh1a2)
GAT: 120810508(aldh1a2) 120811078(aldh1a3)
PPUG: 119197102(aldh1a2) 119198453(aldh1a3)
MSAM: 119883181(aldh1a3) 119890022(aldh1a2) 119892392
CUD: 121509741 121510222(aldh1a2) 121510572(aldh1a3)
MZE: 101467043(aldh1a2) 101472510(aldh1a1)
ONL: 100709766(aldh1a2) 100710237(aldh1a1)
OAU: 116323019 116334580(aldh1a2)
OLA: 100049450(aldh1a2)
OML: 112139085(aldh1a3) 112161158(aldh1a2)
XMA: 102225737(aldh1a2) 102232034(aldh1a3)
XCO: 114142943(aldh1a2) 114143203(aldh1a3)
XHE: 116718396(aldh1a3) 116718605(aldh1a2)
PRET: 103462270(aldh1a3) 103462518(aldh1a2)
CVG: 107087020(aldh1a3) 107095651(aldh1a2)
CTUL: 119778643(aldh1a2) 119797668(aldh1a3)
NFU: 107381378(aldh1a2)
KMR: 108229802(aldh1a2)
ALIM: 106531687(aldh1a2)
CSEM: 103379028 103398364(aldh1a2)
POV: 109624736(aldh1a3) 109633667(aldh1a1) 109636896(aldh1a2)
LCF: 108878679(aldh1a1) 108887709(aldh1a2) 108894298(aldh1a3)
SDU: 111218496(aldh1a2) 111220437(aldh1a3) 111226670(aldh1a1)
SLAL: 111644902 111655138(aldh1a2) 111656552(aldh1a3)
XGL: 120791475(aldh1a2) 120791604(aldh1a3) 120805334
HCQ: 109525955(aldh1a2)
BPEC: 110175209(aldh1a2)
MALB: 109965394(aldh1a2) 109973808(aldh1a3)
OTW: 112263245 112263719(aldh1a2) 112264247(aldh1a3)
ELS: 105014397(aldh1a3) 105014483(aldh1a1) 105016492(aldh1a2)
AANG: 118207144 118215636 118226706(aldh1a3) 118226798(aldh1a2)
LOC: 102685231(aldh1a1) 102689169(aldh1a2) 102694141(aldh1a3)
LCM: 102347553(ALDH1A1) 102352592(ALDH1A2) 102366661(ALDH1A3)
CMK: 103182367(aldh1a1) 103187113 103187716(aldh1a3)
SCLV: 120345907
APLC: 110984698
TPRE: 106656269
CCIN: 107270205
MSEX: 115449569
BANY: 112053045
PPOT: 106103486
PXU: 106116038
SDM: 118190454
PCAN: 112555783
ADF: 107345189
SPIS: 111334097
DDI: DDB_G0290479(hydA)
 » show all
Reference
PMID:2591967
  Authors
Hsu LC, Chang WC, Yoshida A
  Title
Genomic structure of the human cytosolic aldehyde dehydrogenase gene.
  Journal
Genomics 5:857-65 (1989)
DOI:10.1016/0888-7543(89)90127-4
  Sequence
[hsa:216]
Reference
  Authors
Molotkov A, Duester G
  Title
Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid.
  Journal
J Biol Chem 278:36085-90 (2003)
DOI:10.1074/jbc.M303709200
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