KEGG ORTHOLOGY: K07423

KEGG

ORTHOLOGY: K07423

Entry

K07423                      KO

Symbol

CYP2W1

Name

cytochrome P450 family 2 subfamily W1 [EC:1.14.14.-]

Pathway

Retinol metabolism

Metabolic pathways

Reaction

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07423  CYP2W1; cytochrome P450 family 2 subfamily W1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07423  CYP2W1; cytochrome P450 family 2 subfamily W1
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
  CYP2 family
   K07423  CYP2W1; cytochrome P450 family 2 subfamily W1

Genes

HSA:	54905(CYP2W1)

PTR:	463213(CYP2W1)

PPS:	100991744(CYP2W1)

GGO:

PON:

PPYG:

NLE:

HMH:

SSYN:

MCC:

MCF:	102118190(CYP2W1)

MTHB:

MNI:

CSAB:

103246893(CYP2W1)

CATY:

PANU:

TGE:

MLEU:

RRO:

RBB:

TFN:

PTEH:

CANG:

CJC:	100410404(CYP2W1)

SBQ:

CIMI:

108288997(CYP2W1)

ANAN:

105729930(CYP2W1)

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	545817(Cyp2w1)

MCAL:

MPAH:

RNO:	288517(Cyp2w1)

MCOC:

ANU:

ASYL:

MUN:

CGE:

MAUA:

PROB:

PLEU:

PMAV:

102905941(Cyp2w1)

MORG:

MFOT:

AAMP:

NGI:

HGL:

CPOC:

CCAN:

DORD:

DSP:

DMER:

138834734(Cyp2w1)

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

OCZ:	121162740 121167050

TUP:

GVR:

CFA:	491601(CYP2W1)

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

MNP:

MLK:

NVS:

ORO:

EJU:

ZCA:

MLX:

NSU:

LWW:

FCA:	101088802(CYP2W1)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

LGF:

AJU:

PPAD:

PUC:

PLEZ:

HHV:

BTA:	618939(CYP2W1)

BOM:	102265968(CYP2W1)

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

CSUM:

138075564(CYP2W1)

ODA:

CCAD:

MREE:

136157321(CYP2W1)

OVR:	110130389(CYP2W1)

MBEZ:

SSC:

CFR:

CBAI:

CDK:

VPC:

BACU:

OOR:

LALB:

GMF:	115850412(CYP2W1)

DDP:	132437707(CYP2W1)

DLE:

PCAD:

PSIU:

116740509 116740575

PPHC:

136134610(CYP2W1)

NASI:

ECB:	100053875(CYP2W1)

EPZ:	103560287(CYP2W1)

EAI:

MYB:

MMYO:

MDT:

MYUM:

139011558(CYP2W1)

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

HAI:

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

SFUM:

SETR:

LAV:

TMU:

ETF:

MDO:

SHR:

AFZ:

PCW:

TVP:

PBRV:

138158707(CYP2W1)

MLAO:

OAA:

GGA:	416453(CYP2W1) 416454(CYP2W2)

PCOC:

116237360 116237362

MGP:	100546874 100547030

CJO:	107320563 107320565

TPAI:

128079033 128079034

LMUT:

125700589 125700590

NMEL:

110406122 110406123

APLA:

101792573 101804267

ACYG:

106033532(CYP2W1) 106033533

CATA:

118249357 118249358

AFUL:

116495279 116495333

TGU:	100224214(CYP2W1)

LSR:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

139598076(CYP2W1)

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

138118545(CYP2W1)

ETL:

ZAB:

ZLE:

ACHL:

SVG:

MMEA:

HRT:

SATI:

136367882(CYP2W1)

CCIC:

FPG:	101915186 101923323

FCH:	102056602 102060191

CCRI:

104160635 104160637

NNT:	104405622 104405625

SHAB:

115606427 115607622

ACUN:

113485583 113485584

TALA:

104358005 104358006

ACHC:

115335656 115335658

HALD:

104314130 104314131

HLE:	104833542 104833543

AGEN:

126034176 126034198

HHAR:

128134691 128134692

GCL:	127022282 127022309

CSTI:

LDI:	104344887 104344888

MNB:	103772616 103772617

DPUB:

PPUS:

AVIT:

104270692 104270694

BRHI:

EGZ:	104128961 104128972

NNI:

PCRI:

104031089 104031090

PCAO:

PADL:

AFOR:

103904855 103904982

FGA:	104072263 104079069

CBOR:

142089152 142089154

GSTE:

104260195 104261483

CBOY:

140658845 140658846(CYP2W1)

MAME:

142415838 142415888(CYP2W1)

CLV:

CNIC:

MUI:	104545852 104545854

PGUU:

104465023 104465025

PLET:

EHS:

CMAC:

104480056 104480057

CUCA:

104065986 104066008

TEO:	104374924 104374925

BREG:

104637153 104637154

OHA:	104337920 104337926

ACAR:

104531330 104531331

CVF:	104287118 104287420

RTD:	128913807 128914146

CRID:

134519392 134519393

LMIC:

141747219 141747536

AAM:	106491342 106491343

AROW:

112974378 112974379

NPD:	112959863 112959926

TGT:	104578049 104578051

DNE:	112992853 112992854

SCAM:

104153945 104153946

ASN:

AMJ:

CPOO:

109314747 109314748

GGN:	109294512 109294514

PSS:

CIZ:

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:

ACS:	100551965(cyp2w3) 100560793(cyp2w1)

ASAO:

132765056 132780021 132782132

PVT:	110084706 110087209

SUND:

121914222 121914525

PBI:	103060913 103061481

PMUR:

107289130 107291888

CTIG:

120315715 120319311

TSR:

PGUT:

117676771 117679538

PCAE:

139325129 139325473

APRI:

131185090 131185331

PTEX:

113439006 113452741 113452743

NSS:	113422404 113423608

VKO:	123024938 123025024

PMUA:

114583958 114584598

PRAF:

128401455 128401671

ZVI:	118093050 118093197

HCG:	128336452 128336682

GJA:	107120518 107124231

STOW:

125430571 125432141

EMC:	129338978 129340695

NPR:	108798036 108798716

RTEM:

120943446 120943447

ACAT:

141148926 141148928 141148929

PADS:

140334509 140334510 140335231 140335232

BBUF:

121008250 121008883 121008884

BGAR:

122939570 122944473 122944474

DTC:	141047820 141058954(CYP2W1) 141079542

LJP:

Reference

Authors

Karlgren M, Gomez A, Stark K, Svard J, Rodriguez-Antona C, Oliw E, Bernal ML, Ramon y Cajal S, Johansson I, Ingelman-Sundberg M

Title

Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

Journal

Biochem Biophys Res Commun 341:451-8 (2006)
DOI:10.1016/j.bbrc.2005.12.200

Sequence

[hsa:54905]

Reference

Authors

Zhao Y, Wan D, Yang J, Hammock BD, Ortiz de Montellano PR

Title

Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates.

Journal

Drug Metab Dispos 44:771-80 (2016)
DOI:10.1124/dmd.116.069633

LinkDB

DBGET integrated database retrieval system