KEGG   ORTHOLOGY: K07593
Entry
K07593                      KO                                     
Symbol
SLC2A2, GLUT2
Name
MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Pathway
map04911  Insulin secretion
map04917  Prolactin signaling pathway
map04922  Glucagon signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04950  Maturity onset diabetes of the young
map04973  Carbohydrate digestion and absorption
map05230  Central carbon metabolism in cancer
Disease
H00069  Glycogen storage disease
H01947  Fanconi-Bickel syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04922 Glucagon signaling pathway
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04917 Prolactin signaling pathway
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04950 Maturity onset diabetes of the young
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04931 Insulin resistance
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC2: Facilitative GLUT transporter
   K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
 Major facilitator superfamily (MFS)
  Sugar transporters
   Sugar porter (SP) family
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Other DBs
GO: 0005355
TC: 2.A.1.1.29
Genes
HSA: 6514(SLC2A2)
PTR: 460848(SLC2A2)
PPS: 100983878(SLC2A2)
GGO: 101126141(SLC2A2)
PON: 100437366(SLC2A2)
NLE: 100603133(SLC2A2)
MCC: 695538(SLC2A2)
MCF: 102130700(SLC2A2)
CSAB: 103221255(SLC2A2)
CATY: 105586069(SLC2A2)
PANU: 101022043(SLC2A2)
TGE: 112618751(SLC2A2)
RRO: 104660535(SLC2A2)
RBB: 108515004(SLC2A2)
TFN: 117083729(SLC2A2)
PTEH: 111543526(SLC2A2)
CJC: 100397713(SLC2A2)
SBQ: 101053596(SLC2A2)
CSYR: 103260645(SLC2A2)
MMUR: 105855416(SLC2A2)
LCAT: 123630261(SLC2A2)
OGA: 100955667(SLC2A2)
MMU: 20526(Slc2a2)
MCAL: 110291094(Slc2a2)
MPAH: 110320473(Slc2a2)
RNO: 25351(Slc2a2)
MCOC: 116095027(Slc2a2)
MUN: 110545687(Slc2a2)
CGE: 100750908(Slc2a2)
MAUA: 101827043(Slc2a2)
PLEU: 114697557(Slc2a2)
MORG: 121452876(Slc2a2)
AAMP: 119826881(Slc2a2)
NGI: 103731696(Slc2a2)
HGL: 101699012(Slc2a2)
CPOC: 100733937(Slc2a2)
CCAN: 109682261(Slc2a2)
DORD: 105985578(Slc2a2)
DSP: 122107286(Slc2a2)
NCAR: 124992591
OCU: 100338918(SLC2A2)
OPI: 101533428(SLC2A2)
TUP: 102497006(SLC2A2)
CFA: 488165(SLC2A2)
VVP: 112926672(SLC2A2)
VLG: 121477379(SLC2A2)
AML: 100475889(SLC2A2)
UMR: 103676147(SLC2A2)
UAH: 113255119(SLC2A2)
UAR: 123786389(SLC2A2)
ELK: 111150341
LLV: 125100360
MPUF: 101670937(SLC2A2)
ORO: 101367009(SLC2A2)
EJU: 114207055(SLC2A2)
ZCA: 113918857(SLC2A2)
MLX: 118000275(SLC2A2)
FCA: 100142681(SLC2A2)
PYU: 121033988(SLC2A2)
PBG: 122491735(SLC2A2)
PTG: 102961271(SLC2A2)
PPAD: 109275126(SLC2A2)
AJU: 106990050(SLC2A2)
HHV: 120234618(SLC2A2)
BTA: 282357(SLC2A2)
BOM: 102277237(SLC2A2)
BIU: 109558192(SLC2A2)
BBUB: 102400959(SLC2A2)
CHX: 102176460(SLC2A2)
OAS: 443205(SLC2A2)
ODA: 120869759(SLC2A2)
CCAD: 122444940(SLC2A2)
SSC: 397429(SLC2A2)
CFR: 102524363(SLC2A2)
CBAI: 105063293(SLC2A2)
CDK: 105086009(SLC2A2)
VPC: 102540787(SLC2A2)
BACU: 103000646(SLC2A2)
LVE: 103086850(SLC2A2)
OOR: 101285939(SLC2A2)
DLE: 111174077(SLC2A2)
PCAD: 102984344(SLC2A2)
PSIU: 116753535(SLC2A2)
ECB: 100033974(SLC2A2)
EPZ: 103546363(SLC2A2)
EAI: 106847542(SLC2A2)
MYB: 102257921(SLC2A2)
MYD: 102773357(SLC2A2)
MMYO: 118677395(SLC2A2)
MLF: 102417181(SLC2A2)
MNA: 107529525(SLC2A2)
PKL: 118723607(SLC2A2)
HAI: 109383439(SLC2A2)
DRO: 112304870(SLC2A2)
SHON: 118987406(SLC2A2)
AJM: 119043438(SLC2A2)
PDIC: 114515126(SLC2A2)
PHAS: 123827541(SLC2A2)
MMF: 118617351(SLC2A2)
RFQ: 117012522(SLC2A2)
PALE: 102883555(SLC2A2)
PGIG: 120604383(SLC2A2)
PVP: 105305684(SLC2A2)
RAY: 107501411(SLC2A2)
MJV: 108398018(SLC2A2)
TOD: 119257284(SLC2A2)
SARA: 101557379(SLC2A2)
LAV: 100669209(SLC2A2)
TMU: 101356489
MDO: 100010342(SLC2A2)
GAS: 123242829(SLC2A2)
SHR: 100923865(SLC2A2)
PCW: 110203994(SLC2A2)
OAA: 100086793(SLC2A2)
GGA: 396272(SLC2A2)
PCOC: 116243383(SLC2A2)
MGP: 100539563(SLC2A2)
CJO: 107318334(SLC2A2)
NMEL: 110398099(SLC2A2)
APLA: 101803907(SLC2A2)
ACYG: 106031994(SLC2A2)
AFUL: 116492598(SLC2A2)
TGU: 100218276(SLC2A2)
LSR: 110480353(SLC2A2)
SCAN: 103815293(SLC2A2)
PMOA: 120504366(SLC2A2)
OTC: 121336562(SLC2A2)
PRUF: 121353718(SLC2A2)
GFR: 102038277(SLC2A2)
FAB: 101820821(SLC2A2)
PHI: 102102379(SLC2A2)
PMAJ: 107208774(SLC2A2)
CCAE: 111933593(SLC2A2)
CCW: 104688041(SLC2A2)
ETL: 114061180(SLC2A2)
ZAB: 102066121(SLC2A2)
FPG: 101924748(SLC2A2)
FCH: 102053009(SLC2A2)
CLV: 102090795(SLC2A2)
EGZ: 104132471(SLC2A2)
NNI: 104022055(SLC2A2)
PLET: 104625247(SLC2A2)
ACUN: 113483593(SLC2A2)
TALA: 104359800(SLC2A2)
PADL: 103924962(SLC2A2)
ACHC: 115347487(SLC2A2)
AAM: 106486598(SLC2A2)
AROW: 112963921(SLC2A2)
NPD: 112952330(SLC2A2)
DNE: 112986486(SLC2A2)
ASN: 102372548(SLC2A2)
AMJ: 102573725(SLC2A2)
CPOO: 109308434(SLC2A2)
GGN: 109287981(SLC2A2)
PSS: 102451172
CMY: 102940285(SLC2A2)
CPIC: 101951250(SLC2A2)
TST: 117882596(SLC2A2)
CABI: 116826731(SLC2A2)
MRV: 120372697(SLC2A2)
ACS: 100553701(slc2a2)
PVT: 110079055(SLC2A2)
SUND: 121924669(SLC2A2)
PBI: 103063859(SLC2A2)
PMUR: 107296419(SLC2A2)
PGUT: 117678191(SLC2A2)
VKO: 123025636(SLC2A2)
PMUA: 114597978(SLC2A2)
ZVI: 118093772(SLC2A2)
GJA: 107111899(SLC2A2)
STOW: 125437955(SLC2A2)
XLA: 108718098(slc2a2.S) 432042(slc2a2.L)
XTR: 496943(slc2a2)
NPR: 108784826(SLC2A2)
RTEM: 120936748(SLC2A2)
BBUF: 120997886(SLC2A2)
BGAR: 122935854(SLC2A2)
DRE: 322493(slc2a2)
SANH: 107680265
PPRM: 120481840(slc2a2)
MAMB: 125250265(slc2a2)
IPU: 108278343(slc2a2)
PHYP: 113524403
SMEO: 124394937(slc2a2)
TFD: 113637288(slc2a2)
AMEX: 103022443(slc2a2)
EEE: 113576487(slc2a2)
TRU: 101065501(slc2a2)
LCO: 104920046
NCC: 104958942
CGOB: 115027616
ELY: 117267619(slc2a2)
PLEP: 121953232(slc2a2)
SLUC: 116057458(slc2a2)
ECRA: 117936006(slc2a2)
PFLV: 114546584(slc2a2)
GAT: 120833405(slc2a2)
PPUG: 119227239(slc2a2)
MSAM: 119910326(slc2a2)
CUD: 121526087(slc2a2)
ALAT: 119034379(slc2a2)
MZE: 101482471(slc2a2)
ONL: 100534484
OAU: 116318068(slc2a2)
OLA: 101166670(slc2a2)
OML: 112149193(slc2a2)
XMA: 102220025(slc2a2)
XCO: 114133742(slc2a2)
XHE: 116708659(slc2a2)
PRET: 103458415(slc2a2)
PFOR: 103146530(slc2a2)
PLAI: 106951030
PMEI: 106932772(slc2a2)
GAF: 122846519(slc2a2)
CVG: 107085104(slc2a2)
CTUL: 119788182(slc2a2)
GMU: 124855282(slc2a2)
NFU: 107392074(slc2a2)
KMR: 108249199(slc2a2)
ALIM: 106534351(slc2a2)
NWH: 119427386(slc2a2)
AOCE: 111569440(slc2a2)
CSEM: 103378916(slc2a2)
POV: 109636361(slc2a2)
SSEN: 122783194(slc2a2)
HHIP: 117756586(slc2a2)
HSP: 118116257(slc2a2)
LCF: 108874900(slc2a2)
SDU: 111225928
SLAL: 111665821(slc2a2)
XGL: 120795143(slc2a2)
HCQ: 109517287(slc2a2)
BPEC: 110157356(slc2a2)
MALB: 109969620(slc2a2)
BSPL: 114848972(slc2a2)
OTW: 112239038(slc2a2) 112239991
SNH: 120033239 120033537(slc2a2)
ELS: 105019809
SFM: 108935126(slc2a2)
PKI: 111850509
AANG: 118229437(slc2a2)
LOC: 102694631(slc2a2)
PSPA: 121326393(slc2a2)
LCM: 102359756(SLC2A2)
CMK: 103189327(slc2a2)
RTP: 109928470
 » show all
Reference
PMID:3399500
  Authors
Fukumoto H, Seino S, Imura H, Seino Y, Eddy RL, Fukushima Y, Byers MG, Shows TB, Bell GI
  Title
Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein.
  Journal
Proc Natl Acad Sci U S A 85:5434-8 (1988)
DOI:10.1073/pnas.85.15.5434
  Sequence
[hsa:6514]
Reference
  Authors
Kellett GL, Brot-Laroche E, Mace OJ, Leturque A
  Title
Sugar absorption in the intestine: the role of GLUT2.
  Journal
Annu Rev Nutr 28:35-54 (2008)
DOI:10.1146/annurev.nutr.28.061807.155518
Reference
  Authors
Zhao FQ, Keating AF
  Title
Functional properties and genomics of glucose transporters.
  Journal
Curr Genomics 8:113-28 (2007)
DOI:10.2174/138920207780368187
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