KEGG   ORTHOLOGY: K08199
Entry
K08199                      KO                                     
Symbol
SLC22A2, OCT2
Name
MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
Pathway
map05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K08199  SLC22A2, OCT2; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08199  SLC22A2, OCT2; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   K08199  SLC22A2, OCT2; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family
    K08199  SLC22A2, OCT2; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
Other DBs
GO: 0015101
TC: 2.A.1.19.5 2.A.1.19.19
Genes
HSA: 6582(SLC22A2)
PTR: 463113(SLC22A2)
PPS: 100993981(SLC22A2)
GGO: 101148444(SLC22A2)
PON: 100173770(SLC22A2)
NLE: 100601634(SLC22A2)
MCC: 708988(SLC22A2)
MCF: 102115748(SLC22A2)
MTHB: 126953655
CSAB: 103240835(SLC22A2)
CATY: 105581316(SLC22A2)
PANU: 101004885(SLC22A2)
TGE: 112623046(SLC22A2)
RRO: 104666416(SLC22A2)
RBB: 108516183(SLC22A2)
TFN: 117096919(SLC22A2)
PTEH: 111547341(SLC22A2)
CANG: 105506728(SLC22A2)
CJC: 100389525(SLC22A2)
SBQ: 101042083(SLC22A2)
CSYR: 103270364(SLC22A2)
MMUR: 105868622
LCAT: 123633435(SLC22A2)
PCOQ: 105812380(SLC22A2)
OGA: 100950308(SLC22A2)
MMU: 20518(Slc22a2)
MCAL: 110283858
MPAH: 110338260
RNO: 29503(Slc22a2)
MCOC: 116077272(Slc22a2)
MUN: 110554857
CGE: 100761164(Slc22a2)
MAUA: 101839965(Slc22a2)
PLEU: 114691367(Slc22a2)
MORG: 121466558
MFOT: 126497718
AAMP: 119820989
NGI: 103736998
HGL: 101705648(Slc22a2)
CPOC: 100725634(Slc22a2)
CCAN: 109682992(Slc22a2)
DORD: 105991839(Slc22a2)
DSP: 122116100(Slc22a2)
NCAR: 124988906
OCU: 100008831(SLC22A2)
OPI: 101517194
TUP: 102499187(SLC22A2)
GVR: 103609699(SLC22A2)
CFA: 403655(SLC22A2)
CLUD: 112644396(SLC22A2)
VVP: 112935125(SLC22A2)
VLG: 121485205(SLC22A2)
AML: 100476246
UMR: 103660828(SLC22A2)
UAR: 123797543(SLC22A2)
ELK: 111158722
LLV: 125103162
MPUF: 101674303(SLC22A2)
ORO: 101380785(SLC22A2)
EJU: 114209344(SLC22A2)
ZCA: 113926212(SLC22A2)
NSU: 110583403(SLC22A2)
LWW: 102745867
FCA: 101095017
PYU: 121013219(SLC22A2)
PBG: 122490154
LRUF: 124529004
PTG: 102962708(SLC22A2)
PPAD: 109245397
AJU: 106989428(SLC22A2)
HHV: 120223341
BTA: 521027(SLC22A2)
BOM: 102278628(SLC22A2)
BIU: 109564098
BBUB: 102401580(SLC22A2)
BBIS: 104989263(SLC22A2)
CHX: 102184151
OAS: 101111810(SLC22A2)
ODA: 120862820(SLC22A2)
CCAD: 122434157(SLC22A2)
SSC: 396936(SLC22A2)
CFR: 102520738
CBAI: 105077371(SLC22A2)
CDK: 105086292(SLC22A2)
VPC: 102542019
BACU: 103003333(SLC22A2)
LVE: 103074419(SLC22A2)
OOR: 101278261(SLC22A2)
DLE: 111169066(SLC22A2)
PCAD: 102979957
PSIU: 116763180(SLC22A2)
ECB: 100050608(SLC22A2)
EPZ: 103544056(SLC22A2)
EAI: 106842043(SLC22A2)
MYB: 102261214(SLC22A2)
MYD: 102757112(SLC22A2)
MMYO: 118660587(SLC22A2)
MLF: 102442660(SLC22A2)
MNA: 107535726(SLC22A2)
PKL: 118705481(SLC22A2)
HAI: 109393995(SLC22A2)
DRO: 112297414(SLC22A2)
SHON: 118995703(SLC22A2)
AJM: 119034906(SLC22A2)
PHAS: 123821283(SLC22A2)
MMF: 118621502(SLC22A2)
RFQ: 117015715(SLC22A2)
PALE: 102888009
PGIG: 120617524
PVP: 105305672(SLC22A2)
RAY: 107514735
MJV: 108409362(SLC22A2)
TOD: 119253031(SLC22A2)
SARA: 101551973(SLC22A2)
LAV: 100657389
TMU: 101341188
ETF: 101655217(SLC22A2)
DNM: 101432466(SLC22A2)
MDO: 100032472(SLC22A2)
GAS: 123243745
SHR: 100927429(SLC22A2)
PCW: 110208614
OAA: 100078540(SLC22A2)
GGA: 421583(SLC22A2) 421584
TGU: 100229480(SLC22A2)
LSR: 110476047(SLC22A2)
SCAN: 103820557(SLC22A2)
PMOA: 120501493(SLC22A2)
OTC: 121346313(SLC22A2)
PRUF: 121354889(SLC22A2)
GFR: 102036263(SLC22A2)
FAB: 101813287(SLC22A2)
PHI: 102104504
PMAJ: 107202069(SLC22A2)
CCAE: 111927667(SLC22A2)
CBRC: 103619437(SLC22A2) 103619438
ZAB: 102061951(SLC22A2)
ACHL: 103801393
FPG: 101917665 101917841(SLC22A2)
NNI: 104013791
PCRI: 104035158
PCAO: 104045368 104045369(SLC22A2)
ACHC: 115344488
HALD: 104320901
HLE: 104842261
AGEN: 126039048
GSTE: 104257294 104257295(SLC22A2)
LDI: 104340576(SLC22A2)
OHA: 104334712
NNT: 104413756
AVIT: 104276557 104276558(SLC22A2)
CVF: 104295736 104295753(SLC22A2)
BRHI: 104499197
AAM: 106486781
AROW: 112966408(SLC22A2)
NPD: 112951967(SLC22A2)
TGT: 104572307(SLC22A2)
DNE: 112988999
SCAM: 104152816
AMJ: 102560867 102561113(SLC22A2)
CPOO: 109320067(SLC22A2) 109320068
GGN: 109304299(SLC22A2) 109304300
CMY: 102936674(SLC22A2) 102936907
CPIC: 101932729(SLC22A2) 101945044
PBI: 103048478(SLC22A2) 103048709
TSR: 106548798(SLC22A2) 106548799
XLA: 398989 447497(slc22a2.L)
XTR: 100487774(slc22a2)
NPR: 108794552(SLC22A2)
BBUF: 120998702(SLC22A2)
BGAR: 122936070(SLC22A2)
DRE: 406424(slc22a2)
SRX: 107727631
PPRM: 120493457(slc22a2) 120493806
MAMB: 125278396(slc22a2)
IPU: 108257975(slc22a2)
PHYP: 113532298(slc22a2)
SMEO: 124376525(slc22a2)
TFD: 113648209(slc22a2)
AMEX: 103036098
EEE: 113570022(slc22a2)
TRU: 101072186 101076211(slc22a2)
LCO: 104934221 104934232(slc22a2)
ECRA: 117961193(slc22a2)
ESP: 116706007
CVG: 107083500
KMR: 108250275 108250276(slc22a2)
NWH: 119418373(slc22a2)
SLAL: 111672495(slc22a2)
XGL: 120788845(slc22a2)
HCQ: 109523495
MALB: 109953267
BSPL: 114849360(slc22a2) 114849361
SASA: 100196777(s22a2) 106607798(S22A2)
OTW: 112217435 112218081(slc22a2)
OMY: 110522221(slc22a2) 110529598
OGO: 123990740 123995077(slc22a2)
CCLU: 121548936(slc22a2) 121552583 121552585
SFM: 108928506
PKI: 111836197(slc22a2)
AANG: 118230681(slc22a2)
LOC: 102695243
ARUT: 117410870
PSEX: 120516772
LCM: 102364982
FAS: 105267033
AGIF: 122849339
DPA: 109536592
ATD: 109602064
PPYR: 116163010
ZCE: 119840536
PXY: 105386971
CLEC: 106667907
PTRU: 123502943
DFR: 124491290
CRG: 105339854
 » show all
Reference
PMID:8702418
  Authors
Okuda M, Saito H, Urakami Y, Takano M, Inui K
  Title
cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.
  Journal
Biochem Biophys Res Commun 224:500-7 (1996)
DOI:10.1006/bbrc.1996.1056
  Sequence
[rno:29503]
Reference
  Authors
Klaassen CD, Aleksunes LM
  Title
Xenobiotic, bile acid, and cholesterol transporters: function and regulation.
  Journal
Pharmacol Rev 62:1-96 (2010)
DOI:10.1124/pr.109.002014
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