KEGG ORTHOLOGY: K08208

ORTHOLOGY: K08208

Entry

K08208                      KO

Symbol

SLC22A12, URAT1

Name

MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12

Disease

H00948

Renal hypouricemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
   04147 Exosome
    K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family
    K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12

Other DBs

GO:

0015143

TC:	2.A.1.19.11 2.A.1.19.14

Genes

HSA:	116085(SLC22A12)

PTR:	743768(SLC22A12)

PPS:	100992384(SLC22A12)

GGO:	101124776(SLC22A12)

PON:	100448949(SLC22A12)

NLE:	100603239(SLC22A12)

HMH:	116468248(SLC22A12)

MCC:	717530(SLC22A12)

MCF:	102146441(SLC22A12)

MTHB:

126935572

MNI:

105477838

CSAB:

103233185(SLC22A12)

CATY:

105577482(SLC22A12)

PANU:

101008216(SLC22A12)

TGE:	112606654(SLC22A12)

MLEU:

105549108(SLC22A12)

RRO:	104673252(SLC22A12)

RBB:	108542822(SLC22A12)

TFN:	117081427(SLC22A12)

PTEH:

111522352(SLC22A12)

CANG:

105512203(SLC22A12)

CJC:	100403727(SLC22A12)

SBQ:	101052936(SLC22A12)

CIMI:

108310289(SLC22A12)

CSYR:

103255710(SLC22A12)

MMUR:

105878484

LCAT:

123641417

PCOQ:

105827227(SLC22A12)

OGA:	100963879(SLC22A12)

MMU:	20521(Slc22a12)

MCAL:

110285925

MPAH:

110334679

RNO:	365398(Slc22a12)

MCOC:

116103457(Slc22a12)

ANU:

117693202

MUN:

110549333

CGE:	100756772(Slc22a12)

MAUA:

101835453(Slc22a12)

PROB:

127228757(Slc22a12)

PLEU:

114680712(Slc22a12)

MORG:

121454663(Slc22a12)

MFOT:

126498644

AAMP:

119803154

NGI:	103738785(Slc22a12)

HGL:	101714998(Slc22a12)

CPOC:

100721051(Slc22a12)

CCAN:

109687189(Slc22a12)

DORD:

105989245(Slc22a12)

PLOP:

125362083(Slc22a12)

NCAR:

124958989

MMMA:

107135127 107160370(Slc22a12)

OCU:

127489161

OPI:	101533135(SLC22A12)

TUP:	102467876(SLC22A12)

GVR:	103607772(SLC22A12)

CFA:	483761(SLC22A12)

CLUD:

112659460(SLC22A12)

VVP:	112924304(SLC22A12)

VLG:	121472187(SLC22A12)

NPO:	129500841(SLC22A12)

AML:	100463979(SLC22A12)

UMR:	103679555(SLC22A12)

UAH:	113244164(SLC22A12)

UAR:	123778296(SLC22A12)

ELK:

111150109

LLV:

125078644

MPUF:

101682071(SLC22A12)

MNP:	132019387(SLC22A12)

MLK:	131814854(SLC22A12)

NVS:	122913070(SLC22A12)

ORO:	101371050(SLC22A12)

EJU:	114220455(SLC22A12)

ZCA:	113914967(SLC22A12)

MLX:	118015636(SLC22A12)

NSU:	110575952(SLC22A12)

LWW:

102731301

FCA:	101100592(SLC22A12)

PYU:	121023677(SLC22A12)

PBG:	122483969(SLC22A12)

PVIV:

125177206(SLC22A12)

LRUF:

124506325

PPAD:

109246676(SLC22A12)

PUC:

125931545

AJU:

106981752

HHV:	120240216(SLC22A12)

BTA:	526067(SLC22A12)

BOM:	102273515(SLC22A12)

BIU:	109554122(SLC22A12)

BBUB:

102392275(SLC22A12)

BBIS:

104987255(SLC22A12)

CHX:	102191588(SLC22A12)

OAS:	101117630(SLC22A12)

BTAX:

128068584(SLC22A12)

ODA:

120874095

CCAD:

122431113(SLC22A12)

MBEZ:

129548337(SLC22A12)

SSC:	100520540(SLC22A12)

CFR:	102513360(SLC22A12)

CDK:	105101556(SLC22A12)

VPC:	102540541(SLC22A12)

BACU:

103019288(SLC22A12)

BMUS:

118899612(SLC22A12)

PCAD:

102993139(SLC22A12)

ECB:	100055832(SLC22A12)

EPZ:	103565065(SLC22A12)

EAI:	106833672(SLC22A12)

MMYO:

118665354(SLC22A12)

PKL:	118714969(SLC22A12)

EFUS:

103302093(SLC22A12)

MNA:	107542791(SLC22A12)

DRO:	112317335(SLC22A12)

SHON:

118991683(SLC22A12)

AJM:	119050241(SLC22A12)

PDIC:

114499152(SLC22A12)

PHAS:

123829468(SLC22A12)

PPAM:

129068604(SLC22A12)

RFQ:	117031207(SLC22A12)

PALE:

102882211

MJV:	108396367(SLC22A12)

TOD:	119250532(SLC22A12)

SARA:

101538137(SLC22A12)

SETR:

126017647(SLC22A12)

LAV:	100661855(SLC22A12)

TMU:

101348787

ETF:

101653818

DNM:

101429625

MDO:	100013502(SLC22A9) 100031325(SLC22A12)

GAS:	123251313(SLC22A12)

SHR:

100928235

AFZ:

127540091

PCW:	110195538(SLC22A12)

OAA:	100075618 100087819

DSV:

119458935

RMP:	119186232 119186472

» show all

Reference

PMID:12024214

Authors

Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H

Title

Molecular identification of a renal urate anion exchanger that regulates blood urate levels.

Journal

Nature 417:447-52 (2002)
DOI:10.1038/nature742

Sequence

[hsa:116085]

LinkDB

DBGET integrated database retrieval system