KEGG ORTHOLOGY: K10100

ORTHOLOGY: K10100

Entry

K10100                      KO

Symbol

FBXO6

Name

F-box protein 6

Pathway

map04141

Protein processing in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K10100  FBXO6; F-box protein 6
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10100  FBXO6; F-box protein 6
  09183 Protein families: signaling and cellular processes
   04091 Lectins
    K10100  FBXO6; F-box protein 6
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit type E3
   SCF complex
    Target recognizing subunit (F-box)
     K10100  FBXO6; F-box protein 6
Lectins [BR:ko04091]
F-box lectins
  K10100  FBXO6; F-box protein 6

Genes

HSA:	26270(FBXO6)

PTR:	469799(FBXO6)

PPS:	100978399(FBXO6)

GGO:	129523487(FBXO6)

PON:	100452785(FBXO6)

PPYG:

129007836(FBXO6)

NLE:	100596230(FBXO6)

HMH:	116812927(FBXO6)

SSYN:

129472725(FBXO6)

MCC:	722740(FBXO6)

MCF:	102122963(FBXO6)

MTHB:

126953294

MNI:	105473159(FBXO6)

CSAB:

103225604(FBXO6)

CATY:

105580865(FBXO6)

PANU:

101017409(FBXO6)

TGE:	112634398(FBXO6)

MLEU:

105551380(FBXO6)

RRO:	104654353(FBXO6)

RBB:	108539377(FBXO6)

TFN:	117093317(FBXO6)

PTEH:

111526301(FBXO6)

CANG:

105507364(FBXO6)

CJC:	100388028 100388826(FBXO6)

SBQ:	101045283(FBXO6)

CIMI:

108286382(FBXO6)

ANAN:

105731791(FBXO6)

CSYR:

103276116(FBXO6)

MMUR:

105882721(FBXO6)

LCAT:

123634473

ERUF:

138390451

PCOQ:

105824962(FBXO6)

OGA:

100956609

MMU:	50762(Fbxo6)

MCAL:

110292525(Fbxo6)

MPAH:

110322838

RNO:	192351(Fbxo6)

MCOC:

116097010(Fbxo6)

ANU:

117708538

ASYL:

127681658(Fbxo6)

MUN:	110555754(Fbxo6)

CGE:

100762938

MAUA:

101832562

PROB:

127213159

PLEU:

114709645(Fbxo6)

MORG:

121441781 121448119

MFOT:

126508193

AAMP:

119816380

NGI:	103732819(Fbxo6)

HGL:	101723682(Fbxo6)

CPOC:

100724661

CCAN:

109697788(Fbxo6)

DORD:

105999754(Fbxo6)

DSP:

122121410

DMER:

138838178(Fbxo6)

PLOP:

125354574

NCAR:

124982376

MMMA:

107155496(Fbxo6)

ITI:	101955143(Fbxo6)

OCU:

100351389

OPI:

101525143

OCZ:	121161498(FBXO6)

TUP:	102481362(FBXO6)

GVR:	103605246(FBXO6)

CFA:	487444(FBXO6)

CLUD:

112678110(FBXO6)

VVP:	112929746(FBXO6)

VLG:	121496724(FBXO6)

NPO:	129513379(FBXO6)

AML:

100471620

UMR:	103666655(FBXO6)

UAH:	113270505(FBXO6)

UAR:	123779098(FBXO6)

ELK:

111154886

LLV:

125098029

MPUF:

101674087(FBXO6)

MNP:

132001209

MLK:

131809090

NVS:

122899453

ORO:	101365951(FBXO6)

EJU:	114213283(FBXO6)

ZCA:	113938760(FBXO6)

MLX:	118020003(FBXO6)

MANO:

123860072(FBXO6)

NSU:	110574665(FBXO6)

LWW:	102741380(FBXO44)

FCA:	101100065(FBXO6)

PYU:	121021130(FBXO6)

PCOO:

112861547

PBG:	122479926(FBXO6)

PVIV:

125173130(FBXO6)

LRUF:

124515094

LGF:	123597183(FBXO6)

AJU:

106971874

PPAD:

109274109

PUC:

125913113

PLEZ:

122227396(FBXO6)

HHV:	120233628(FBXO6)

CCRU:

144231375(FBXO6)

BTA:	513023(FBXO6)

BOM:	102285878(FBXO6)

BIU:	109570547(FBXO6)

BBUB:

102391070(FBXO6)

BKE:	129653047(FBXO6)

BBIS:

104995842(FBXO6)

CHX:

102183714

OAS:	101112337(FBXO6)

BTAX:

128061453(FBXO6)

CSUM:

138090818

ODA:	120880222(FBXO6)

CCAD:

122451964(FBXO6)

MREE:

136168375(FBXO6)

OVR:	110136761(FBXO6)

MBEZ:

129551537(FBXO6)

SSC:	100524148(FBXO6)

CFR:	102506356(FBXO6)

CBAI:

105070968(FBXO6)

CDK:	105107031(FBXO6)

VPC:	102531486(FBXO6)

BACU:

103001158(FBXO6)

BMUS:

118895820(FBXO6)

LVE:	103084160(FBXO6)

OOR:	101285947(FBXO6)

LALB:

132515232(FBXO6)

GMF:	115864569(FBXO6)

DDP:

132427167

DLE:	111187094(FBXO6)

PCAD:

102988702(FBXO6)

PSIU:

116755211(FBXO6)

PPHC:

136123065(FBXO6)

NASI:

112402691(FBXO6)

ECB:	100056376(FBXO6)

EPZ:

103552186

EAI:

106836671

MYB:	102243764(FBXO6)

MYD:	102765136(FBXO6)

MMYO:

MLF:

MDT:

MYUM:

PKL:

EFUS:

MNA:	107540999(FBXO6)

DRO:

112299112

SHON:

118986345

PDIC:

114496503 114496504 114496857

PHAS:

123831671 123831744

MMF:	118626454(FBXO6)

PPAM:

129075653(FBXO6)

HAI:	109381276(FBXO6)

RFQ:

117027036

PALE:

102883225(FBXO6)

PGIG:

120585817(FBXO6)

PVP:	105294365(FBXO6)

RAY:	107513116 107513117(FBXO6)

MJV:

108385725

TOD:	119235623(FBXO6)

SARA:

101555463(FBXO6)

SFUM:

130020335 130020336(FBXO6)

SETR:

126011570 126011571 126011596 126011618

LAV:	100662009(FBXO6)

TMU:

101360494

DNM:

101432307

MDO:	100018391 100018430

GAS:

123240309

SHR:	100930430 100930696

AFZ:	127555870 127555871

PCW:	110199112 110199167

TVP:	118835807 118838721

PBRV:

MLAO:

OAA:

TACU:

GGA:	419494(FBXO6)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

AACU:

OJA:

ACYG:

106040232(FBXO44)

CATA:

AFUL:

TGU:

LSR:

AIB:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

GFR:	102039786(FBXO6)

FAB:	101818615(FBXO6)

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

ETL:

ZAB:

ZLE:

ACHL:

SVG:

MMEA:

HRT:

SATI:

136370762(FBXO44)

CCIC:

134053017

FPG:	101912079(FBXO6)

FCH:

CCRI:

NNT:

SHAB:

ACUN:

ANOC:

SURA:

TALA:

ACHC:

HALD:

HLE:

AGEN:

HHAR:

BBUT:

GCL:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

135190430(FBXO6)

IIN:

128977510

AVIT:

104272608(FBXO6)

BRHI:

EGZ:

NNI:

PCRI:

PCAO:

PARX:

PADL:

AFOR:

FGA:

CBOR:

GSTE:

CBOY:

140661447(FBXO44)

MAME:

142418705(FBXO44)

CLV:	102090619(FBXO6)

CNIC:

135997330(FBXO6)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

TEO:

BREG:

GAME:

129215815(FBXO44)

OHA:

ACAR:

CPEA:

CVF:

RTD:	128918300(FBXO6)

CRID:

134524017(FBXO6)

LMIC:

141732221(FBXO6)

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:

AMJ:	102558537(FBXO6)

CPOO:

109314270(FBXO6)

GGN:

109293547

PSS:	102445687 102457268

CIZ:	142001075 142001076

CMY:

102946605

CCAY:

125624247(FBXO44)

LKP:

140900257

NDS:

142000737

DCC:	119845000(FBXO44)

CPIC:

TST:

CABI:

MRV:

ACS:	100560165 103281550

PVT:

110073142

SUND:

121928997 121936144 121936147

PBI:	103052803 103059618 112540039

PMUR:

107294609 107299412

CTIG:

120313263

TSR:	106549764 106555729

PGUT:

117659695 117673066 117673067

PCAE:

139325986 139326006 139326099 139326243

APRI:

131186987 131187099 131187190

PTEX:

113446279 113446281 113450035

NSS:	113423135 113423137 113427979

VKO:	123031018 123031056 123031082

PMUA:

114602433 114602813 114602814 114602950 114602983 114603207

PRAF:

128419809 128419815 128419816 128419817 128419822 128419862 128419870 128420329 128420341 128420342 128420414

ZVI:	118086834 118086836 118087072 118087359 118087792

HCG:	128338433 128338434

GJA:	107108921 107108922 107117729

STOW:

125445798 125445894 125445895

EMC:	129344374 129344513 129344863

XLA:	495428(fbxo6.S)

XTR:

101731802

NPR:	108796312 108796314 108796315 108796317 108796322

RTEM:

120915508 120915509 120915645 120943004

ACAT:

141111127 141111128 141111277 141148348 141148349 141148352

PADS:

140340272 140341432

BBUF:

120999484 120999523

BGAR:

122926823 122928827 122928829

DTC:

PWL:

MUO:

GSH:

DRE:	570101(fbxo6.3) 574002(fbxo44.7)

SRX:	107707743 107747974

SANH:

107657006 107657062 107671949

SGH:	107559474 107559475 107603135

CCAR:

109049048 109079807

CAUA:

113041155 113071079 113094745 113106354 113106521 113106636

CGIB:

PTET:

LROH:

GRF:

OMC:	131531529 131531554 131544571

PPRM:

MAMB:

CERY:

MASI:

TROS:

TDW:

MANU:

IPU:

PHYP:

SMEO:

TFD:

TVC:

AMEX:

CMAO:

EEE:

TRU:

TFS:

TNG:	GSTEN00023598G001

LCO:

104924677

NCC:	104961354 104961358

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117257975 117258160

EFO:	125891949 125891950

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:	120829884 120829885 120829890

PPUG:

119221852 119221853 119223024

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

119905235 119905236 119905237

SCHU:

122883121

EARM:

139288553 139288956

CUD:	121517067 121517341 121517746

SPUL:

LMIX:

HTC:

ALAT:

ASTR:

PKLU:

MZE:

ONL:	100697217 109196254

OAU:

116319508

OLA:	101167959 111947667

OML:

112159132

CSAI:

133456845

XMA:	102224931 102236652 102236911 111612299

XCO:	114144342 114144408 114144499 114144565 114145803

XHE:	116734206 116734294 116734538 116734623

PRET:

103467679 103467680 103467682 103467948

PFOR:

103144056 103144057

PLAI:

106954116 106954140 106954164

PMEI:

106922243 106922245 106922246

GAF:	122839561 122839573 122839593

CVG:	107083892 107083932

CTUL:

119782006 119782044 119782045

GMU:	124867542 124874669 124878201

NFU:	107376295 107390474

KMR:	108231943 108231955 108232069

ALIM:

106519313 106519314 106519317

NWH:	119417237 119417239 119417541

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:

BSPL:

SJO:

SSCO:

SASA:

106567261 106572395 106572398

STRU:

115165773 115165774 115168103

OTW:	112216157 112216158 112221930

OMY:	110492151 110532458 110532460

OGO:	124032025 124032026 124045903

ONE:	115102344 115132317 115132319

OKI:	109869606 109908141 109908142(fbxo44)

OKE:	118359865 118360864

OMM:	135504245 135528244

OCLA:

139368590 139416648

SALP:

111966619 111976936

SNH:	120059211 120059212 120061166

SFON:

129830020 129830023 129860808

CCLU:

121538498

ELS:	105013743 105022393

SFM:	108940215 108940221

PKI:	111834354 111834356

AROT:

135235201 135246650

CCOG:

133139431

LOC:	102699183(fbxo6)

PSPA:

121329257 121329367

ARUT:

117426069 117968642

LCM:	102345432(FBXO6)

CMK:

CPLA:

HOC:

SCAU:

LERI:

HAKA:

BFO:

BBEL:

SPU:

APLC:

110986562 110986569 110986582

AAMU:

AFIL:

SKO:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

NMEA:

SOC:

MPHA:

AEC:	105147999 105152832

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

COBS:

TLN:	139808375 139824705

TAME:

HST:

DQU:

CFO:

FEX:	115233182 115242595 115242596

PMEC:

138938797 138939015 138939016

LHU:

PGC:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

TPRE:

MDL:

CGLO:

CTYP:

FAS:

DAM:

VCAN:

CCIN:

DSM:	124414707 124414708

NPT:	124223500 124223501

NFB:	124187105 124187109

NLO:	107225107 107225109

NVG:	124309208 124309209

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:	115891049 115891561

RFG:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

CCRN:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

LDA:	142319108 142319110

PHU:	Phum_PHUM490920

FOC:

TPAL:

ZNE:

PAME:

BROR:

HAMR:

FCD:

PVM:

PCHN:

HAME:

SPRM:

MNZ:

MRJ:

PORN:

HAZT:

OOT:

TCF:

DALB:

CSCU:

CVS:

UDV:

SDM:

NAI:	NECAME_09953

BMY:	BM_BM11070(Bm11070)

LOA:	LOAG_18227

HRF:	124124540 124127925 124145762

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MMER:

123530019 123549188 123549190

RPHI:

132713991 132747471

DPOL:

127836482 127836483 127875003

MAEA:

128207394 128207597 128208389 128208808 128209140

LJP:

LAK:

DGT:

Reference

PMID:12939278

Authors

Yoshida Y, Tokunaga F, Chiba T, Iwai K, Tanaka K, Tai T.

Title

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.

Journal

J Biol Chem 278:43877-84 (2003)
DOI:10.1074/jbc.M304157200

Sequence

[mmu:50762]

Reference

PMID:18203720

Authors

Glenn KA, Nelson RF, Wen HM, Mallinger AJ, Paulson HL

Title

Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

Journal

J Biol Chem 283:12717-29 (2008)
DOI:10.1074/jbc.M709508200

Sequence

[hsa:26270]

LinkDB

DBGET integrated database retrieval system