KEGG ORTHOLOGY: K11160

ORTHOLOGY: K11160

Entry

K11160                      KO

Symbol

DGAT2

Name

diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75]

Pathway

map00561

Glycerolipid metabolism

map01100

Metabolic pathways

map04975

Fat digestion and absorption

Module

M00089

Triacylglycerol biosynthesis

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    K11160  DGAT2; diacylglycerol O-acyltransferase 2
09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K11160  DGAT2; diacylglycerol O-acyltransferase 2
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.20  diacylglycerol O-acyltransferase
     K11160  DGAT2; diacylglycerol O-acyltransferase 2
    2.3.1.75  long-chain-alcohol O-fatty-acyltransferase
     K11160  DGAT2; diacylglycerol O-acyltransferase 2

Other DBs

RN:

R02251

GO:

0004144

Genes

HSA:	84649(DGAT2)

PTR:	466714(DGAT2)

PPS:	100987880(DGAT2)

GGO:	101124779(DGAT2)

PON:	100442216(DGAT2)

NLE:	100596453(DGAT2)

MCC:	696549(DGAT2)

MCF:	102128601(DGAT2)

MTHB:

126935091

CSAB:

103248066(DGAT2)

CATY:

105578724(DGAT2)

PANU:

101004164(DGAT2)

TGE:	112606124(DGAT2)

RRO:	104665097(DGAT2)

RBB:	108545121(DGAT2)

TFN:	117079794(DGAT2)

PTEH:

111540820(DGAT2)

CANG:

105511813(DGAT2)

CJC:	100414192(DGAT2)

SBQ:	101049433(DGAT2)

CSYR:

103260163(DGAT2)

MMUR:

105860306(DGAT2)

LCAT:

123641013(DGAT2)

PCOQ:

105811518(DGAT2)

OGA:	100955161(DGAT2)

MMU:	67800(Dgat2)

MCAL:

110298238(Dgat2)

MPAH:

110327696(Dgat2)

RNO:	252900(Dgat2)

MCOC:

116102617(Dgat2)

MUN:	110566217(Dgat2)

CGE:	100774981(Dgat2)

MAUA:

101828109(Dgat2)

PLEU:

114698694(Dgat2)

MORG:

121447603 121451992 121458609 121464703

MFOT:

126489000 126508923

AAMP:

119802438(Dgat2)

NGI:	103743019(Dgat2)

HGL:	101698712(Dgat2)

CPOC:

100718670(Dgat2)

CCAN:

109680743(Dgat2)

DORD:

105984115(Dgat2)

DSP:	122116390(Dgat2)

NCAR:

124959932

OCU:

100354838

OPI:	101531109(DGAT2)

TUP:	102494423(DGAT2)

GVR:	103594072(DGAT2)

CFA:	485185(DGAT2)

CLUD:

112642159(DGAT2)

VVP:	112928729(DGAT2)

VLG:	121476006(DGAT2)

AML:	100468811(DGAT2)

UMR:	103678126(DGAT2)

UAH:	113269335(DGAT2)

UAR:	123804196(DGAT2)

ELK:

111159441

LLV:

125079109

MPUF:

101683621(DGAT2)

ORO:	101385232(DGAT2)

EJU:	114218654(DGAT2)

ZCA:	113914191(DGAT2)

MLX:	118004222(DGAT2)

NSU:	110593398(DGAT2)

LWW:	102734307(DGAT2)

FCA:	101100329(DGAT2)

PYU:	121039297(DGAT2)

PBG:	122483320(DGAT2)

LRUF:

124504588

PTG:	102952153(DGAT2)

PPAD:

109267215(DGAT2)

AJU:	106976464(DGAT2)

HHV:	120229587(DGAT2)

BTA:	404129(DGAT2)

BOM:	102285649(DGAT2)

BIU:	109569733(DGAT2)

BBUB:

102404874(DGAT2)

BBIS:

104994095(DGAT2)

CHX:	102174409(DGAT2)

OAS:	101110535(DGAT2)

ODA:	120876775(DGAT2)

CCAD:

122449555(DGAT2)

SSC:	100294675(DGAT2) 110259135

CFR:	102504113(DGAT2)

CBAI:

105083331(DGAT2)

CDK:	105097240(DGAT2)

VPC:	102543460(DGAT2)

BACU:

103018277(DGAT2)

LVE:	103075069(DGAT2)

OOR:	101283358(DGAT2)

DLE:	111184877(DGAT2)

PCAD:

102991226(DGAT2)

PSIU:

116758860(DGAT2)

ECB:	100064387(DGAT2)

EPZ:	103548227(DGAT2)

EAI:	106840399(DGAT2)

MYB:	102249216 102261774(DGAT2)

MYD:	102753473(DGAT2)

MMYO:

118664624(DGAT2)

MLF:	102432364(DGAT2)

MNA:	107524453(DGAT2)

PKL:	118712749(DGAT2)

HAI:	109386362(DGAT2)

DRO:	112316013(DGAT2)

SHON:

118981593(DGAT2)

AJM:	119038935(DGAT2)

PDIC:

114500700(DGAT2)

PHAS:

123805549(DGAT2)

MMF:	118628088(DGAT2)

RFQ:	117030228(DGAT2)

PALE:

102898739(DGAT2)

PGIG:

120590367(DGAT2)

PVP:	105297629(DGAT2)

RAY:	107519183(DGAT2)

MJV:	108404469(DGAT2)

TOD:	119255640(DGAT2)

SARA:

101537208(DGAT2)

LAV:	100657191(DGAT2)

TMU:

101355455

ETF:	101643400 101650984(DGAT2)

DNM:	101425617(DGAT2)

MDO:	100011089(DGAT2)

GAS:	123240512(DGAT2)

SHR:	100914285(DGAT2)

PCW:	110210559(DGAT2)

OAA:	100088895(DGAT2)

GGA:	421309(DGAT2) 428693(AWAT1)

PCOC:

116229501 116237128(DGAT2)

MGP:	100540643 100545351(DGAT2)

CJO:	107308594(DGAT2) 107312638

NMEL:

110392121(DGAT2) 110403393

APLA:

101801215(DGAT2)

ACYG:

106042403(DGAT2) 106042952

AFUL:

116493702(DGAT2) 116494455

TGU:	100220095(DGAT2) 100232309

LSR:	110471640(DGAT2) 110474359

SCAN:

103816429 103823769(DGAT2)

PMOA:

120502902(DGAT2) 120508757

OTC:	121331883 121345447(DGAT2)

PRUF:

121353434(DGAT2) 121363220

GFR:	102035873(DGAT2) 102037230

FAB:	101810713(DGAT2) 101820931

PHI:	102100921 102107779(DGAT2)

PMAJ:

107204039 107211569(DGAT2)

CCAE:

111928595 111941011(DGAT2)

CCW:	104686963(DGAT2) 104691343

CBRC:

103613828(DGAT2) 103623291

ETL:	114059609(DGAT2) 114065167

ZAB:	102067962(DGAT2)

ACHL:

103810882(DGAT2) 103811539

FPG:	101917877 101924658(DGAT2)

FCH:	102055207(DGAT2) 102057990

CLV:	102085339 102087439(DGAT2)

EGZ:	104124768(DGAT2) 104135988

NNI:	104012839 104022725(DGAT2)

PLET:

104623782(DGAT2)

PCRI:

104027365(DGAT2)

PCAO:

104049548(DGAT2)

ACUN:

113481155(DGAT2)

TALA:

104359568(DGAT2) 116963760

PADL:

103915186(DGAT2) 103919207

AFOR:

103904653(DGAT2) 103906155

ACHC:

115333797 115353408(DGAT2)

HALD:

104311450(DGAT2)

HLE:	104834787 104837474(DGAT2)

AGEN:

126048145 126050190

GCL:	127019631 127027094

CCRI:

104155569(DGAT2)

CSTI:

104561220(DGAT2)

EHS:	104503936 104506915(DGAT2)

CMAC:

104481279(DGAT2)

MUI:	104546500(DGAT2) 104546921

FGA:	104073309(AWAT2)

GSTE:

104251567(DGAT2)

LDI:

104353992

MNB:	103774229(DGAT2)

OHA:	104326275(DGAT2)

NNT:	104413348(DGAT2)

DPUB:

104297009 104302402(DGAT2)

PGUU:

104467335(DGAT2)

ACAR:

104522911(DGAT2) 104529705

CPEA:

104387831 104397247(DGAT2)

AVIT:

104268809(DGAT2)

CVF:	104283492 104291467(DGAT2)

CUCA:

104054299 104064126(DGAT2)

TEO:	104375044 104380910(DGAT2)

BRHI:

104497704(DGAT2)

AAM:	106482698 106486174 106494604

AROW:

112966308 112970398(DGAT2)

NPD:	112942305 112948691(DGAT2)

TGT:	104566185 104571431(AWAT1)

DNE:	112980802 112981932(DGAT2)

SCAM:

104152363 104152792(DGAT2)

ASN:	102370139 102371123(DGAT2)

AMJ:	102557932(DGAT2) 102576534(AWAT2)

CPOO:

109306877(DGAT2) 109310891

GGN:	109300474 109303156(DGAT2)

PSS:	102449336 102453357(DGAT2)

CMY:	102929519 102930862(DGAT2)

CPIC:

101930999(DGAT2) 101950557

TST:	117871307(DGAT2) 117882695

CABI:

116817074 116834584(DGAT2) 116834701

MRV:	120371561 120405842(DGAT2)

ACS:	100552736(dgat2) 100555636

PVT:	110074308 110087798(DGAT2)

SUND:

121925502(DGAT2) 121936266

PBI:	103052621(DGAT2)

PMUR:

107299528

CTIG:

120318288

PGUT:

117679844(DGAT2)

VKO:	123027242 123033546(DGAT2)

PMUA:

114589371 114595553(DGAT2)

ZVI:	118084502 118085303(DGAT2)

GJA:	107110553 107112091(DGAT2)

STOW:

125425197 125430796(DGAT2)

XLA:	100126612(awat1.L) 100127341(awat1.S) 108698316(dgat2l6.L) 108710042(dgat2.S) 108710383(mogat3.L) 398800(dgat2.L)

XTR:	100127622(awat1) 100127752(dgat2l6) 100491581(mogat3) 395003(dgat2)

NPR:	108785624 108792522(DGAT2) 108795426(MOGAT3) 108796935

RTEM:

120928929(DGAT2) 120933489(MOGAT3) 120936575

BBUF:

120977260 120986523 120993143 120996506 120996508 120996509 120996510 120997731

BGAR:

122923132 122923133 122929349 122930942 122931919 122932546 122935739 122946501

DRE:	494083(mogat3b) 565316(dgat2)

SRX:	107746411 107746984 107752358

SANH:

107661213 107663414 107686128(dgat2) 107691652

SGH:	107578632 107588782(dgat2) 107596103 107599198(mogat3)

CCAR:

109052109 109068531 109090750 109098086

CAUA:

113049110 113049603 113054403 113077530 113109920

PPRM:

120469793(mogat3b) 120469794 120482752(dgat2)

MAMB:

125262200(dgat2) 125266968(mogat3b)

IPU:	100528806(dgat2) 108259936(mogat3b)

PHYP:

113524198(dgat2) 113531204

SMEO:

124379331(mogat3b) 124393940(dgat2)

TFD:	113641502(mogat3b) 113650339(dgat2)

AMEX:

103043884(dgat2) 103047166 111194470

EEE:	113589528(dgat2) 113590600

TRU:	101071223 101079383(dgat2)

TNG:	GSTEN00016290G001 GSTEN00022150G001

LCO:	104931787(dgat2) 104937288

NCC:	104942132(dgat2)

CGOB:

115018989(dgat2) 115019169

ELY:	117246453(dgat2) 117264098(mogat3b)

EFO:	125898139(mogat3b) 125899027(dgat2)

PLEP:

121952909(dgat2) 121953073(mogat3b)

SLUC:

116058252(dgat2) 116064928(mogat3b)

ECRA:

117955304(dgat2) 117955838(mogat3b)

ESP:	116677659 116700625 116700701(dgat2)

PFLV:

114566209 114566643(dgat2)

GAT:	120821650(mogat3b) 120822783(dgat2)

PPUG:

119215522(dgat2) 119215717(mogat3b)

MSAM:

119895050(mogat3b) 119895214(dgat2)

CUD:	121518318(dgat2) 121518425(mogat3b)

ALAT:

119031173(mogat3b) 119031819(dgat2)

MZE:	101484727 101485008(dgat2)

ONL:	100707401 100709028(dgat2)

OAU:	116320588(dgat2) 116330302(mogat3b)

OLA:	101166733 101175675(dgat2)

OML:	112142473(mogat3b) 112142623(dgat2)

XMA:	102219836(dgat2) 102228247

XCO:	114152662 114153067(dgat2)

XHE:	116728361(dgat2) 116728435

PRET:

103475773 103476122(dgat2)

PFOR:

103142114(dgat2) 103145629

PLAI:

106951574(dgat2) 106953369

PMEI:

106922189 106926391(dgat2)

GAF:	122844303(mogat3b) 122845257(dgat2)

CVG:	107097472(dgat2) 107099793

CTUL:

119771282(dgat2) 119789592(mogat3b)

GMU:	124876339(mogat3b) 124876553(dgat2)

NFU:	107386011(dgat2) 107386510

KMR:	108244705(dgat2) 108248268(mogat3b)

ALIM:

106517203(dgat2) 106535072

NWH:	119420166(mogat3b) 119420715(dgat2)

AOCE:

111577661 111587031(dgat2)

MCEP:

125020837(mogat3b) 125021413(dgat2)

CSEM:

103394818(dgat2) 103395417

POV:	109628346 109628731(dgat2)

SSEN:

122779148(dgat2) 122779643(mogat3b)

HHIP:

117774123(dgat2) 117774187(mogat3b)

HSP:	118122023(mogat3b) 118122513 118122590(dgat2)

LCF:	108893507(mogat3b) 108893792

SDU:	111222364(dgat2) 111234506

SLAL:

111653950 111663527(dgat2)

XGL:	120802291(dgat2) 120802722(mogat3b)

HCQ:	109531183(dgat2)

BPEC:

110158360 110165125(dgat2)

MALB:

109959536 109972857(dgat2)

BSPL:

114869513(mogat3b) 114869858(dgat2)

SASA:

106567948 106581137 106603399 106603538

STRU:

115148293 115148893 115154352 115154431 115163481

OTW:	112233379 112257827

OMY:	110503985 110507812 110508071 110523205 110533663 110533733(mogat3b) 110537459

OGO:	123989459 123992475 124000096 124009767 124010412

ONE:	115104779 115105564 115135832 115135895

SALP:

111950522 111981045

SNH:	120018018 120025469 120041785 120045187(dgat2) 120057077 120057118(mogat3b)

CCLU:

121559152 121568006 121568310 121573579 121579776 121580310 121582010

ELS:	105005790 105010982(dgat2)

SFM:	108936020(dgat2)

PKI:	111858447(dgat2)

AANG:

118209231 118235037(mogat3b) 118235735(dgat2)

LOC:	102684783(dgat2)

PSPA:

121305669 121306615 121320386(dgat2)

ARUT:

117405472 117406788 117968116

PSEX:

120523348(dgat2) 120525108

LCM:	102351093(DGAT2) 102359647(MOGAT3) 102360601

CMK:	103188598(dgat2) 103190916

RTP:	109918725 109923339

HHAL:

TPAL:

EAF:

ATEN:

Reference

PMID:19116371

Authors

Shi Y, Cheng D

Title

Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism.

Journal

Am J Physiol Endocrinol Metab 297:E10-8 (2009)
DOI:10.1152/ajpendo.90949.2008

Reference

PMID:11481335

Authors

Cases S, Stone SJ, Zhou P, Yen E, Tow B, Lardizabal KD, Voelker T, Farese RV Jr

Title

Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.

Journal

J Biol Chem 276:38870-6 (2001)
DOI:10.1074/jbc.M106219200

Sequence

[hsa:84649]

LinkDB

DBGET integrated database retrieval system