KEGG   ORTHOLOGY: K12097
Entry
K12097                      KO                                     
Symbol
cag12
Name
cag pathogenicity island protein 12
Pathway
map05120  Epithelial cell signaling in Helicobacter pylori infection
Module
M00564  Helicobacter pylori pathogenicity signature, cagA pathogenicity island
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K12097  cag12; cag pathogenicity island protein 12
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K12097  cag12; cag pathogenicity island protein 12
Secretion system [BR:ko02044]
 Type IV secretion system
  Cag pathogenicity island (PAI) protein
   K12097  cag12; cag pathogenicity island protein 12
Other DBs
TC: 3.A.7.12.1
Genes
HPY: HP_0532
HEO: C694_02745
HPJ: jhp_0481(cagT)
HPA: HPAG1_0508
HPS: HPSH_04260
HHP: HPSH112_04385
HHQ: HPSH169_02725
HHR: HPSH417_02540
HPG: HPG27_491(cagT)
HPP: HPP12_0539(cagT)
HPL: HPB8_711(cagT)
HPI: hp908_0536(cag12)
HPQ: hp2017_0514(cag12)
HPW: hp2018_0516(cag12)
HEF: HPF16_0823(cagT)
HPF: HPF30_0792(cagT)
HEQ: HPF32_0511(cagT)
HEX: HPF57_0562(cagT)
HPZ: HPKB_0810
HPD: KHP_0787(cag12)
HEY: MWE_0990
HPYO: HPOK113_0552(cagT)
HPYL: HPOK310_0797(cagT)
HPYR: K747_06725
HPYI: K750_04110
HPYU: K751_03285
HPYM: K749_01360
HEB: U063_0840
HEZ: U064_0843
 » show all
Reference
  Authors
Kutter S, Buhrdorf R, Haas J, Schneider-Brachert W, Haas R, Fischer W
  Title
Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies.
  Journal
J Bacteriol 190:2161-71 (2008)
DOI:10.1128/JB.01341-07
Reference
  Authors
Fischer W, Puls J, Buhrdorf R, Gebert B, Odenbreit S, Haas R
  Title
Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8.
  Journal
Mol Microbiol 42:1337-48 (2001)
DOI:10.1046/j.1365-2958.2001.02714.x
  Sequence
[hpy:HP_0532]
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