KEGG   ORTHOLOGY: K12722
Entry
K12722            Tight     KO                                     
Symbol
cloN6, couN6
Name
clorobiocin/coumermycin A biosynthesis protein CloN6/CouN6
Pathway
map00401  Novobiocin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R06768  
R06775  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00401 Novobiocin biosynthesis
    K12722  cloN6, couN6; clorobiocin/coumermycin A biosynthesis protein CloN6/CouN6
Genes
SBRO: GQF42_07525
AG: AAG29791(couN6) AAN65235(cloN6)
Reference
  Authors
Pojer F, Li SM, Heide L.
  Title
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.
  Journal
Microbiology 148:3901-11 (2002)
DOI:10.1099/00221287-148-12-3901
  Sequence
Reference
  Authors
Sattely ES, Fischbach MA, Walsh CT
  Title
Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways.
  Journal
Nat Prod Rep 25:757-93 (2008)
DOI:10.1039/b801747f
LinkDB

KEGG   REACTION: R06775
Entry
R06775                      Reaction                               
Definition
Novclobiocin 104 + Pyrrole-2-carbonyl-[pcp] <=> Clorobiocin
Equation
Comment
methyltransferase, CloN6
acyl transferase, CloN7
incomplete reaction
Reaction class
RC00055  C12032_C12473
Pathway
rn00401  Novobiocin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K12722  clorobiocin/coumermycin A biosynthesis protein CloN6/CouN6
K12724  clorobiocin/coumermycin A biosynthesis protein CloN7/CouN7
LinkDB

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