KEGG ORTHOLOGY: K12804

ORTHOLOGY: K12804

Entry

K12804                      KO

Symbol

PSTPIP1

Name

proline-serine-threonine phosphatase interacting protein 1

Pathway

map04621

NOD-like receptor signaling pathway

Disease

H00287

Pyogenic sterile arthritis, pyoderma gangrenosum, and acne syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Bin/Amphiphysin/Rvs (BAR) family proteins
   F-BAR proteins
    K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1

Genes

HSA:	9051(PSTPIP1)

PTR:	100613166(PSTPIP1)

PPS:	129393990(PSTPIP1)

GGO:	129527155(PSTPIP1)

PON:	100449454(PSTPIP1)

PPYG:

129014487(PSTPIP1)

NLE:	100598955(PSTPIP1)

HMH:	116482563(PSTPIP1)

SSYN:

129482205(PSTPIP1)

MCC:	708327(PSTPIP1)

MCF:	102128978(PSTPIP1)

MTHB:

126960006

MNI:	105491018(PSTPIP1)

CSAB:

103245274(PSTPIP1)

CATY:

105601336(PSTPIP1)

PANU:

101022104(PSTPIP1)

TGE:	112627867(PSTPIP1)

MLEU:

105541587(PSTPIP1)

RRO:	104670089(PSTPIP1)

RBB:	108528518(PSTPIP1)

TFN:	117070341(PSTPIP1)

PTEH:

111530433(PSTPIP1)

CANG:

105505129(PSTPIP1)

CJC:	100406340(PSTPIP1)

SBQ:	101052332(PSTPIP1)

CIMI:

108296000(PSTPIP1)

ANAN:

105720913(PSTPIP1)

CSYR:

103257694(PSTPIP1)

MMUR:

105882058(PSTPIP1)

LCAT:

123624689(PSTPIP1)

ERUF:

138374339(PSTPIP1)

PCOQ:

105816457(PSTPIP1)

OGA:	100964952(PSTPIP1)

MMU:	19200(Pstpip1)

MCAL:

110301923(Pstpip1)

MPAH:

110328148(Pstpip1)

RNO:	300732(Pstpip1)

MCOC:

116072082(Pstpip1)

ANU:	117699200(Pstpip1)

ASYL:

127689037(Pstpip1)

MUN:	110566271(Pstpip1)

CGE:	100765031(Pstpip1)

MAUA:

101842060(Pstpip1)

PROB:

127231780(Pstpip1)

PLEU:

114690315(Pstpip1)

PMAV:

102917075(Pstpip1)

MORG:

121438303(Pstpip1)

MFOT:

126486932

AAMP:

119809816(Pstpip1)

CNL:	130873344(Pstpip1)

NGI:	103726044(Pstpip1)

HGL:	101723975(Pstpip1)

CPOC:

100732350(Pstpip1)

CCAN:

109697411(Pstpip1)

DORD:

105982498(Pstpip1)

DSP:	122123426(Pstpip1)

DMER:

138841886(Pstpip1)

PLOP:

125368238(Pstpip1)

NCAR:

124978001

MMMA:

107137922(Pstpip1)

ITI:	101954771(Pstpip1)

OCU:

103345318

OPI:	101526759(PSTPIP1)

OCZ:	121148450(PSTPIP1)

TUP:	102479779(PSTPIP1)

GVR:	103609243(PSTPIP1)

CFA:	611757(PSTPIP1)

CLUD:

112675543(PSTPIP1)

VVP:	112913261(PSTPIP1)

VLG:	121485579(PSTPIP1)

NPO:	129506318(PSTPIP1)

AML:	100473221(PSTPIP1)

UMR:	103678964(PSTPIP1)

UAH:	113241007(PSTPIP1)

UAR:	123790651(PSTPIP1)

ELK:	111153103 111153380

LLV:

125104664

MPUF:

101690189(PSTPIP1)

MNP:	131999140(PSTPIP1)

MLK:	131835748(PSTPIP1)

NVS:	122893003(PSTPIP1)

ORO:	101370765(PSTPIP1)

EJU:	114200507(PSTPIP1)

ZCA:	113908859(PSTPIP1)

MLX:	118002967(PSTPIP1)

NSU:	110583942(PSTPIP1)

LWW:	102736289(PSTPIP1)

FCA:	101100213(PSTPIP1)

PYU:	121041427(PSTPIP1)

PCOO:

112855511(PSTPIP1)

PBG:	122468385(PSTPIP1)

PVIV:

125168257(PSTPIP1)

LRUF:

124508953

LGF:	123582667(PSTPIP1)

AJU:

106985237

PTG:	102950378(PSTPIP1)

PPAD:

109262645(PSTPIP1)

PUC:

125908946

PLEZ:

122221755(PSTPIP1)

HHV:	120235763(PSTPIP1)

BTA:	513924(PSTPIP1)

BOM:	102285323(PSTPIP1)

BIU:	109575656(PSTPIP1)

BBUB:

102416670(PSTPIP1)

BKE:	129634012(PSTPIP1)

BBIS:

104990959(PSTPIP1)

CHX:	102187808(PSTPIP1)

OAS:	101116939(PSTPIP1)

BTAX:

128066721(PSTPIP1)

CSUM:

138095217(PSTPIP1)

ODA:	120875485(PSTPIP1)

CCAD:

122455173(PSTPIP1)

MREE:

136147137(PSTPIP1)

OVR:	110133493(PSTPIP1)

MBEZ:

129550424(PSTPIP1)

SSC:	100152628(PSTPIP1)

CFR:	102520466(PSTPIP1)

CBAI:

105069163(PSTPIP1)

CDK:	105087228(PSTPIP1)

VPC:	102536186(PSTPIP1)

BACU:

103017173(PSTPIP1)

BMUS:

118890346(PSTPIP1)

LVE:	103084287(PSTPIP1)

OOR:	101274282(PSTPIP1)

LALB:

132523496(PSTPIP1)

GMF:	115862760(PSTPIP1)

DDP:	132418781(PSTPIP1)

DLE:	111177854(PSTPIP1)

PCAD:

102988731(PSTPIP1)

PSIU:

116746191(PSTPIP1)

PPHC:

136118031(PSTPIP1)

NASI:

112410942(PSTPIP1)

ECB:	100050881(PSTPIP1)

EPZ:	103564744(PSTPIP1)

EAI:	106831299(PSTPIP1)

MYB:	102246938(PSTPIP1)

MYD:	102775185(PSTPIP1)

MMYO:

118676300(PSTPIP1)

MLF:	102427837(PSTPIP1)

MYUM:

139020105(PSTPIP1)

PKL:	118728349(PSTPIP1)

EFUS:

103303877(PSTPIP1)

MNA:	107538057(PSTPIP1)

DRO:	112301695(PSTPIP1)

SHON:

118987720(PSTPIP1)

AJM:	119038683(PSTPIP1)

PDIC:

114489697(PSTPIP1)

PHAS:

123825274(PSTPIP1)

MMF:	118643458(PSTPIP1)

PPAM:

129085610(PSTPIP1)

HAI:	109375337(PSTPIP1)

RFQ:	117023553(PSTPIP1)

PALE:

102883260(PSTPIP1)

PGIG:

120597910(PSTPIP1)

PVP:	105306866(PSTPIP1)

RAY:	107510504(PSTPIP1)

MJV:	108402704(PSTPIP1)

TOD:	119238391(PSTPIP1)

SARA:

101555394(PSTPIP1)

SFUM:

130036840(PSTPIP1)

SETR:

126021835(PSTPIP1)

LAV:	100672535(PSTPIP1)

TMU:

101359185

ETF:	101641657(PSTPIP1)

DNM:	101438212(PSTPIP1)

MDO:	100025253(PSTPIP1)

GAS:	123236500(PSTPIP1)

SHR:	100923195(PSTPIP1)

AFZ:

127552066

PCW:	110200615(PSTPIP1)

TVP:	118829035(PSTPIP1)

PBRV:

138148553(PSTPIP1)

MLAO:

141520709(PSTPIP1)

OAA:	103169236(PSTPIP1)

TACU:

119945958(PSTPIP1)

GGA:	415349(PSTPIP1)

PCOC:

116244573(PSTPIP1)

CJO:	107318652(PSTPIP1)

TPAI:

128075140(PSTPIP1)

LMUT:

125698233(PSTPIP1)

NMEL:

110403573(PSTPIP1)

APLA:

101790362(PSTPIP1)

AACU:

137863042(PSTPIP1)

ACYG:

106044213(PSTPIP1)

CATA:

118251622(PSTPIP1)

AFUL:

116493500(PSTPIP1)

TGU:	100218412(PSTPIP1)

LSR:	110477553(PSTPIP1)

SCAN:

103823176(PSTPIP1)

PMOA:

120513292(PSTPIP1)

OTC:	121348343(PSTPIP1)

PRUF:

121365492(PSTPIP1)

ATRC:

139596963(PSTPIP1)

GFR:	102033261(PSTPIP1)

FAB:	101805745(PSTPIP1)

OMA:	130257454(PSTPIP1)

PHI:	102111384(PSTPIP1)

PMAJ:

107209340(PSTPIP1)

CCAE:

111934250(PSTPIP1)

CCW:	104697449(PSTPIP1)

CBRC:

103622928(PSTPIP1)

ACOE:

138116650(PSTPIP1)

ETL:	114064693(PSTPIP1)

ZAB:	102071946(PSTPIP1)

ZLE:	135452219(PSTPIP1)

ACHL:

103798883(PSTPIP1)

SVG:	106854935(PSTPIP1)

MMEA:

130575058(PSTPIP1)

HRT:	120759000(PSTPIP1)

SATI:

136367227(PSTPIP1)

CFAI:

136296666(PSTPIP1)

CCIC:

134049119(PSTPIP1)

FPG:	101922705(PSTPIP1)

FCH:	102053249(PSTPIP1)

CCRI:

104154945(PSTPIP1)

NNT:	104410424(PSTPIP1)

SHAB:

115612895(PSTPIP1)

ACUN:

113484034(PSTPIP1)

SURA:

141948338(PSTPIP1)

TALA:

104359246(PSTPIP1)

ACHC:

115342147(PSTPIP1)

HALD:

104314691(PSTPIP1)

HLE:	104834404(PSTPIP1)

AGEN:

126043311

HHAR:

128151214(PSTPIP1)

BBUT:

142039197(PSTPIP1)

GCL:

127020563

LDI:	104346598(PSTPIP1)

MNB:	103772785(PSTPIP1)

DPUB:

104306070(PSTPIP1)

PPUS:

135182837(PSTPIP1)

AVIT:

104279554(PSTPIP1)

BRHI:

104491363

EGZ:	104130850(PSTPIP1)

NNI:	104016732(PSTPIP1)

PCRI:

104032046(PSTPIP1)

PCAO:

104050262(PSTPIP1)

PARX:

142060188(PSTPIP1)

PADL:

103922041(PSTPIP1)

AFOR:

103898554(PSTPIP1)

FGA:	104077159(PSTPIP1)

CBOR:

142086839(PSTPIP1)

GSTE:

104256822(PSTPIP1)

CBOY:

140655489(PSTPIP1)

MAME:

142411591(PSTPIP1)

CLV:	102093910(PSTPIP1)

CNIC:

135992612(PSTPIP1)

MUI:	104539673(PSTPIP1)

PGUU:

104471743(PSTPIP1)

PLET:

104624727(PSTPIP1)

EHS:	104507194(PSTPIP1)

CMAC:

104476446(PSTPIP1)

CUCA:

104066291(PSTPIP1)

TEO:	104372189(PSTPIP1)

BREG:

104643138(PSTPIP1)

GAME:

129210767(PSTPIP1)

OHA:	104335475(PSTPIP1)

ACAR:

104528425(PSTPIP1)

CPEA:

104385963(PSTPIP1)

CVF:	104287940(PSTPIP1)

RTD:	128914436(PSTPIP1)

CRID:

134521046(PSTPIP1)

LMIC:

141748691(PSTPIP1)

NARQ:

141470086(PSTPIP1)

AAM:	106496439(PSTPIP1)

AROW:

112967280(PSTPIP1)

NPD:	112946732(PSTPIP1)

TGT:	104565091(PSTPIP1)

DNE:	112988760(PSTPIP1)

SCAM:

104148363(PSTPIP1)

ASN:	102384611(PSTPIP1)

AMJ:	102560566(PSTPIP1)

CPOO:

109308891(PSTPIP1)

GGN:	109288721(PSTPIP1)

PSS:	102449303(PSTPIP1)

CIZ:	142019649(PSTPIP1)

CMY:	102932540(PSTPIP1)

CCAY:

125644264(PSTPIP1)

LKP:	140894822(PSTPIP1)

NDS:	141995158(PSTPIP1)

DCC:	119862859(PSTPIP1)

CPIC:

101947383(PSTPIP1)

TST:	117884305(PSTPIP1)

EOB:	135884747(PSTPIP1)

CABI:

116836294(PSTPIP1)

MRV:	120373855(PSTPIP1)

ACS:	100566825(pstpip1)

ASAO:

132762598(PSTPIP1)

PVT:	110087171(PSTPIP1)

SUND:

121932401(PSTPIP1)

PBI:	103063525(PSTPIP1)

PMUR:

107289268(PSTPIP1)

CTIG:

120305575(PSTPIP1)

PGUT:

117661017(PSTPIP1)

PCAE:

139323938(PSTPIP1)

APRI:

131184923(PSTPIP1)

PTEX:

113442318(PSTPIP1)

NSS:	113423239(PSTPIP1)

VKO:	123033726(PSTPIP1)

PMUA:

114604258(PSTPIP1)

PRAF:

128420765(PSTPIP1)

ZVI:	118083613(PSTPIP1)

HCG:	128334871(PSTPIP1)

GJA:	107109701(PSTPIP1)

STOW:

125446119(PSTPIP1)

EMC:	129345495(PSTPIP1)

XLA:	108711276(pstpip1.L) 447609(pstpip1.S)

XTR:	100379705(pstpip1)

NPR:	108796191(PSTPIP1)

RTEM:

120931553(PSTPIP1)

ACAT:

141131660(PSTPIP1)

PADS:

140324283(PSTPIP1)

BBUF:

120985591(PSTPIP1)

BGAR:

122929727(PSTPIP1)

DTC:	141092970(PSTPIP1)

PWL:	138284007(PSTPIP1)

MUO:	115457734(PSTPIP1)

GSH:	117347968(PSTPIP1)

DRE:	571331(pstpip1a) 641582(pstpip1b)

SRX:	107715239 107725740 107741409 107750641

SANH:

107670725 107690351 107691132 107700386

SGH:	107562121 107567896 107585972 107594553

CCAR:

109056588 109077262 109108880(pstpip1a)

CAUA:

113049520 113052290 113061639 113118492

CGIB:

127934446 127961086 127977208 128016984

PTET:

122323031(pstpip1a) 122348046(pstpip1b)

LROH:

127168631(pstpip1b) 127180767(pstpip1a)

GRF:	141332262(pstpip1b) 141345596(pstpip1a)

OMC:	131524811(pstpip1a) 131544926(pstpip1b)

PPRM:

120473182(pstpip1b) 120487692(pstpip1a)

RKG:	130088928(pstpip1a) 130101563(pstpip1b)

MAMB:

125254348(pstpip1a) 125264699(pstpip1b)

CIDE:

127499755 127515140

CERY:

137023424(pstpip1a) 137030484(pstpip1b)

MASI:

127412129 127416258 127416818 127455927

TROS:

130556535(pstpip1b) 130563264(pstpip1a)

TDW:	130421098(pstpip1b) 130435896(pstpip1a)

MANU:

129418589(pstpip1a) 129442667(pstpip1b)

PDAB:

135749272(pstpip1b) 135773487(pstpip1a)

TRN:	134323141(pstpip1a)

AMEX:

103046241(pstpip1a)

CMAO:

118801362(pstpip1a) 118819142(pstpip1b)

EEE:	113576592(pstpip1) 113583492

CHAR:

105905582(pstpip1a)

SPIL:

134093775(pstpip1a)

ASAD:

121724706(pstpip1a)

TRU:	101062992 101065355(pstpip1)

TFS:	130521556 130536205

TNG:	GSTEN00015942G001 GSTEN00021448G001

LCO:	104917774 104917840(pstpip1)

NCC:	104946597 104947250

TBEN:

117471603 117491377(pstpip1a)

CGOB:

115006277 115010266

PGEO:

117440062 117447656(pstpip1a)

GACU:

117556681 117557670(pstpip1a)

EMAC:

134863390 134877973(pstpip1a)

ELY:	117260494 117262430(pstpip1a)

EFO:	125887199(pstpip1a) 125904305

PLEP:

121950252(pstpip1a) 121961158

SLUC:

116038555(pstpip1a) 116060606

ECRA:

117947647 117949218(pstpip1a)

ESP:	116690617 116694070

PFLV:

114559786 114561287

GAT:	120809034(pstpip1a) 120812726 120835114

PPUG:

119195709(pstpip1a) 119196750(pstpip1b)

AFB:	129101547 129108390(pstpip1a)

CLUM:

117725899(pstpip1b) 117732106(pstpip1a)

PSWI:

130193153 130195954(pstpip1a)

CANA:

137800241(pstpip1b) 137804019(pstpip1a)

CVE:	137881423(pstpip1a) 137887442

MSAM:

119885013 119890338(pstpip1b) 119894118(pstpip1a)

SCHU:

122873793(pstpip1b) 122874353(pstpip1a)

EARM:

139284296(pstpip1b) 139285996(pstpip1a)

CUD:	121511165(pstpip1b) 121514921(pstpip1a)

SPUL:

138588415 138612501(pstpip1a)

LMIX:

132972481(pstpip1a) 132975821

HTC:	141787988 141796135(pstpip1a)

ALAT:

119018346(pstpip1b) 119024535(pstpip1a)

ASTR:

137594453(pstpip1a) 137598872

PKLU:

139200614(pstpip1b) 139200923(pstpip1a)

MZE:	101473069 101487370

ONL:	100700076 100700785

OAU:	116314691(pstpip1b) 116326243(pstpip1a)

OLA:	101156493 101174493

OML:	112151763(pstpip1a) 112161319(pstpip1b)

CSAI:

133444237(pstpip1a) 133456525

XMA:	102221102 102228179

XCO:	114143373 114151469(pstpip1)

XHE:	116718871 116732697(pstpip1)

PRET:

103462592 103466606

PFOR:

103147831 103149883

PLAI:

106945589 106946148

PMEI:

106920791 106928283(pstpip1)

GAF:	122835300(pstpip1a) 122846804

PPRL:

129364183(pstpip1b) 129365474(pstpip1a)

CVG:	107082790(pstpip1) 107105107

CTUL:

119772463(pstpip1a) 119780712

GMU:	124866872 124879843(pstpip1a)

NFU:	107381549 107388780

KMR:	108229819(pstpip1a) 108237417(pstpip1b)

ALIM:

106514356(pstpip1) 106534257

NWH:	119415736(pstpip1a) 119426224

AOCE:

111580159(pstpip1a) 111587590

EJA:	138206596(pstpip1a) 138212985

BFRE:

138616314 138626774(pstpip1a)

MCEP:

125005703(pstpip1b) 125015247(pstpip1a)

CSEM:

103379385 103380310(pstpip1)

POV:	109624342 109624918

SSEN:

122769884(pstpip1a) 122772574

SSOE:

131460063 131469540(pstpip1a)

HHIP:

117759149(pstpip1b) 117762566(pstpip1a)

HSP:	118109179(pstpip1a) 118113437(pstpip1b)

PPLT:

128440597 128445032(pstpip1a)

SMAU:

118302455 118314677(pstpip1a)

LCF:	108875280(pstpip1a) 108877030

SDU:	111221465 111228555(pstpip1)

SLAL:

111659169 111667008(pstpip1)

XGL:	120793083(pstpip1a) 120793796

HCQ:	109513963 109531180

SSCV:

125966843 125971115(pstpip1a)

SBIA:

133498073 133502674(pstpip1a)

PEE:	133397293(pstpip1b) 133403304(pstpip1a)

PTAO:

133474258 133478357(pstpip1a)

BPEC:

110156539 110175260

ENY:	140348595(pstpip1a) 140381180

MALB:

109954587 109966304(pstpip1)

BSPL:

114852484 114856865(pstpip1a)

SJO:	128359035(pstpip1a) 128359399

SSCO:

133981999(pstpip1a) 133982143

TTY:	137183037(pstpip1a) 137184900

GMH:	115551218(pstpip1) 115558453

SASA:

106561158 106562406 106562467 106573496 106587680

STRU:

115152003 115166993 115196748 115203327

OTW:	112218582 112246932 112247476 112252406

OMY:	110495782 110506762 110521117 110526640

OGO:	124001141 124033560 124035537 124036509

ONE:	115109419 115112777 115120518 115134241

OKI:	109867315 109881534 109882254 109889367

OKE:	118362688 118375495 118396725(pstpip1a) 118401215

OMM:	135509345(pstpip1a) 135524381 135551464 135556845

OCLA:

139372204 139384878 139405078 139411627

SALP:

111952956 111962416 112068316 112075211

SNH:	120039630 120040387 120053944 120066272

SFON:

129834569 129854493 129862454(pstpip1a) 129867049

CCLU:

121531913 121576609 121580141

ELS:	105022635 105025684

OEP:	134021105(pstpip1a) 134028009

SFM:	108931692 108940843

PKI:	111843575 111846641

AANG:

118214704(pstpip1a) 118227617

AROT:

135242011(pstpip1a) 135255325

CCOG:

133111901(pstpip1a) 133131652

LOC:	102698401(pstpip1)

PSPA:

121294595 121298846

ARUT:

117428116 117429477

PSEX:

120541620(pstpip1a)

LCM:	102348654(PSTPIP1)

CMK:	103188307(pstpip1a)

RTP:	109910951(pstpip1a)

CPLA:

122542541(pstpip1a)

CPUN:

140458418

HOC:

132834760

SCAU:

119956883

LERI:

129713488(pstpip1a)

HAKA:

140714351(pstpip1a)

PMRN:

116950818 116953549

LRJ:	133354195(PSTPIP1) 133355039

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

PFLL:

PVM:

PJA:

PCHN:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

EAF:

TCF:

CSCU:

CVS:

LPOL:

LGI:	LOTGIDRAFT_105043

PVUL:

BARL:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:	125656072 125661596

PMAX:

117332554

AIRR:

138331240

YBA:	132555949 132557909

MMER:

RPHI:

DPOL:

MAEA:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:	124450909 124452209

HMG:

HSY:

RES:

AQU:

CCLM:

MBR:	MONBRDRAFT_23448

SRE:	PTSG_01307

DPP:	DICPUDRAFT_48387

DFA:

DFA_06582

» show all

Reference

PMID:14595024

Authors

Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, Kastner DL

Title

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway.

Journal

Proc Natl Acad Sci U S A 100:13501-6 (2003)
DOI:10.1073/pnas.2135380100

Reference

PMID:9857189

Authors

Li J, Nishizawa K, An W, Hussey RE, Lialios FE, Salgia R, Sunder-Plassmann R, Reinherz EL

Title

A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.

Journal

EMBO J 17:7320-36 (1998)
DOI:10.1093/emboj/17.24.7320

Sequence

[hsa:9051]

LinkDB

DBGET integrated database retrieval system