 | | ORTHOLOGY: K13326 | |
| Entry |
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| Symbol |
megDIII
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| Name |
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.- 2.1.1.234]
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| Pathway |
| map00523 | Polyketide sugar unit biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
| map01250 | Biosynthesis of nucleotide sugars |
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| Module |
| M00797 | dTDP-D-desosamine biosynthesis |
| M00800 | dTDP-L-megosamine biosynthesis |
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| Reaction |
| R06427 | S-adenosyl-L-methionine:dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose 3-N,N-dimethyltransferase |
| R11045 | S-adenosyl-L-methionine:dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose 3-N,N-dimethyltransferase |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
K13326 megDIII; dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.234 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
K13326 megDIII; dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
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| Genes |
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| Reference |
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| Authors |
Useglio M, Peiru S, Rodriguez E, Labadie GR, Carney JR, Gramajo H |
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| Title |
TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli. |
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| Journal |
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| Reference |
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| Authors |
Volchegursky Y, Hu Z, Katz L, McDaniel R |
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| Title |
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea. |
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| Sequence |
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| LinkDB |
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