KEGG   ORTHOLOGY: K13391
Entry
K13391                      KO                                     
Symbol
CYP719B1
Name
salutaridine synthase [EC:1.14.19.67]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00944  Morphine biosynthesis, (S)-reticuline => morphine
Reaction
R04696  (R)-reticuline,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-C phenol-coupling)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K13391  CYP719B1; salutaridine synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K13391  CYP719B1; salutaridine synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.67  salutaridine synthase
     K13391  CYP719B1; salutaridine synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP719 family
   K13391  CYP719B1; salutaridine synthase
Other DBs
GO: 0047055
Genes
PSOM: 113321914 113339274
AG: ABR14720(CYP719B1)
Reference
PMID:19567876
  Authors
Gesell A, Rolf M, Ziegler J, Diaz Chavez ML, Huang FC, Kutchan TM
  Title
CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy.
  Journal
J Biol Chem 284:24432-42 (2009)
DOI:10.1074/jbc.M109.033373
  Sequence
[ag:ABR14720]
LinkDB

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