KEGG   REACTION: R04696
Entry
R04696                      Reaction                               
Name
(R)-reticuline,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-C phenol-coupling)
Definition
(R)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Salutaridine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C05178 + C03024 + C00007 <=> C05179 + C03161 + 2 C00001
Reaction class
RC02285  C05178_C05179
Enzyme
1.14.19.67
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00944  Morphine biosynthesis, (S)-reticuline => morphine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.67
     R04696  (R)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Salutaridine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Orthology
K13391  salutaridine synthase [EC:1.14.19.67]
Other DBs
RHEA: 17716
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