KEGG   ORTHOLOGY: K13564
Entry
K13564            Tight     KO                                     
Symbol
btrG
Name
gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase [EC:4.3.2.6]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K13564  btrG; gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase
Enzymes [BR:ko01000]
 4. Lyases
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.6  gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase
     K13564  btrG; gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase
Other DBs
RN: R08910
Genes
AG: BAE07071(btrG)
Reference
  Authors
Kudo F, Numakura M, Tamegai H, Yamamoto H, Eguchi T, Kakinuma K
  Title
Extended sequence and functional analysis of the butirosin biosynthetic gene cluster in Bacillus circulans SANK 72073.
  Journal
J Antibiot (Tokyo) 58:373-9 (2005)
DOI:10.1038/ja.2005.47
  Sequence
Reference
  Authors
Kudo F, Eguchi T
  Title
Biosynthetic enzymes for the aminoglycosides butirosin and neomycin.
  Journal
Methods Enzymol 459:493-519 (2009)
DOI:10.1016/S0076-6879(09)04620-5
Reference
  Authors
Llewellyn NM, Li Y, Spencer JB
  Title
Biosynthesis of butirosin: transfer and deprotection of the unique amino acid side chain.
  Journal
Chem Biol 14:379-86 (2007)
DOI:10.1016/j.chembiol.2007.02.005
  Sequence
LinkDB

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