KEGG ORTHOLOGY: K13791

ORTHOLOGY: K13791

Entry

K13791                      KO

Symbol

ipaH9.8

Name

invasion plasmid antigen

Pathway

map05131

Shigellosis

Network

nt06182 Shigella
nt06521 NLR signaling

Element

N00941

Shigella IpaH9.8 to NOD-NFKB signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K13791  ipaH9.8; invasion plasmid antigen

Genes

SFL:	CP0226(ipaH9.8)

SFE:	SFxv_5076(ipaH9.8)

SSN:	SSON_P167(ipaH9.8)

SBO:	SBO_P113(ipaH9.8)

SBC:	SbBS512_A0253

SDY:	SDY_P099(ipaH9.8)

Reference

PMID:15950937

Authors

Okuda J, Toyotome T, Kataoka N, Ohno M, Abe H, Shimura Y, Seyedarabi A, Pickersgill R, Sasakawa C

Title

Shigella effector IpaH9.8 binds to a splicing factor U2AF(35) to modulate host immune responses.

Journal

Biochem Biophys Res Commun 333:531-9 (2005)
DOI:10.1016/j.bbrc.2005.05.145

Sequence

[sfl:CP0226]

Reference

PMID:18005683

Authors

Rohde JR, Breitkreutz A, Chenal A, Sansonetti PJ, Parsot C

Title

Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.

Journal

Cell Host Microbe 1:77-83 (2007)
DOI:10.1016/j.chom.2007.02.002

Sequence

[sfl:CP0226]

LinkDB

Homo sapiens (human): 10318

Entry

10318             CDS       T01001

Symbol

TNIP1, ABIN-1, NAF1, VAN, nip40-1

Name

(RefSeq) TNFAIP3 interacting protein 1

K23829

TNFAIP3-interacting protein 1

Organism

hsa Homo sapiens (human)

Pathway

hsa05131

Shigellosis

Network

nt06182 Shigella
nt06521 NLR signaling

Element

N00941

Shigella IpaH9.8 to NOD-NFKB signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    10318 (TNIP1)

SSDB

Motif

Pfam:

CC2-LZ ATG16 DUF4407 Filament

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

5:complement(151029943..151087685)

AA seq 636 aa
MEGRGPYRIYDPGGSVPSGEASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLR
QKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSG
TSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQL
FTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERL
REENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAE
KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ
RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN
KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDR
ERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVEPH
PEHLCGAYPYAYPPMPAMVPHHGFEDWSQIRYPPPPMAMEHPPPLPNSRLFHLPEYTWRL
PCGGVRNPNQSSQVMDPPTARPTEPESPKNDREGPQ

NT seq 1911 nt +upstreamnt +downstreamnt
atggaagggagaggaccgtaccggatctacgaccctgggggcagcgtgccctcaggagag
gcatccgcagcttttgagcgcctagtgaaggagaattcccggctgaaggaaaaaatgcaa
gggataaagatgttaggggagcttttggaagagtcccagatggaagcgaccaggctccgg
cagaaggcagaggagctagtgaaggacaacgagctgctcccaccaccttctccctccttg
ggctccttcgaccccctggctgagctcacaggaaaggactcaaatgtcacagcatctccc
acagcccctgcatgccccagtgacaagccagcaccagtccagaagcctccatccagtggc
acctcctctgaatttgaagtggtcactcctgaggagcagaattcaccagagagcagcagc
catgccaatgcgatggcgctgggccccctgccccgtgaggacggcaacctgatgctgcac
ctgcagcgcctggagaccacgctgagtgtgtgtgccgaggagccggaccacggccagctc
ttcacccacctgggccgcatggccctggagttcaaccgactggcatccaaggtgcacaag
aatgagcagcgcacctccattctgcagaccctgtgtgagcagcttcggaaggagaacgag
gctctgaaggccaagttggataagggcctggaacagcgggatcaggctgccgagaggctg
cgggaggaaaatttggagctcaagaagttgttgatgagcaatggcaacaaagagggtgcg
tctgggcggccaggctcaccgaagatggaagggacaggcaagaaggcagtggctggacag
cagcaggctagtgtgacggcaggtaaggtcccagaggtggtggccttgggcgcagccgag
aagaaggtgaagatgctggagcagcagcgcagtgagctgctggaagtgaacaagcagtgg
gaccagcatttccggtccatgaagcagcagtatgagcagaagatcactgagctgcgtcag
aagctggctgatttgcagaagcaggtgactgacctggaggccgagcgggagcagaagcag
cgtgactttgaccgcaagctcctcctggccaagtccaagattgaaatggaggagaccgac
aaggagcagctgacagcagaggccaaggagctgcgccaaaaggtcaagtacctgcaggat
cagctgagcccactcacccgacagcgtgagtaccaggaaaaggagatccagcggctcaac
aaggccctggaggaagcactgagcatccaaaccccgccatcatctccaccaacagcattt
gggagcccagaaggagcaggggccctcctaaggaaacaggagctggtcacgcagaatgag
ttgctgaaacagcaggtgaagatcttcgaggaggacttccagagggagcgcagtgatcgt
gagcgcatgaatgaggagaaggaagagctgaagaagcaagtggagaagctgcaggcccag
gtcaccctgtcaaatgcccagctaaaagcattcaaagatgaggagaaggcaagagaagcc
ctcagacagcagaagaggaaagcaaaggcctcaggagagcgttaccatgtggagccccac
ccagaacatctctgcggggcctacccctacgcctacccgcccatgccagccatggtgcca
caccatggcttcgaggactggtcccagatccgctacccccctccccccatggccatggag
cacccgcccccactccccaactcgcgcctcttccatctgccggaatacacctggcgtcta
ccctgtggaggggttcgaaatccaaatcagagctcccaagtgatggaccctcccacagcc
aggcctacagaaccagagtctccaaaaaatgaccgtgaggggcctcagtga

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