KEGG   ORTHOLOGY: K14975
Entry
K14975            Tight     KO                                     
Symbol
CODM
Name
codeine 3-O-demethylase [EC:1.14.11.32]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00944  Morphine biosynthesis, (S)-reticuline => morphine
Reaction
R05127  thebaine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating)
R09402  codeine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K14975  CODM; codeine 3-O-demethylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.32  codeine 3-O-demethylase
     K14975  CODM; codeine 3-O-demethylase
Other DBs
GO: 0102805
Genes
PSOM: 113311621 113311630 113311635
AG: ADD85331(CODM)
Reference
PMID:20228795
  Authors
Hagel JM, Facchini PJ
  Title
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.
  Journal
Nat Chem Biol 6:273-5 (2010)
DOI:10.1038/nchembio.317
  Sequence
[ag:ADD85331]
LinkDB

DBGET integrated database retrieval system