KEGG   ORTHOLOGY: K16385
Entry
K16385                      KO                                     
Symbol
amphI, nysI
Name
polyene macrolide polyketide synthase, KS-AT-KR-ACP domains
Pathway
map01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16385  amphI, nysI; polyene macrolide polyketide synthase, KS-AT-KR-ACP domains
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16385  amphI, nysI; polyene macrolide polyketide synthase, KS-AT-KR-ACP domains
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Polyene macrolide PKS
     K16385  amphI, nysI; polyene macrolide polyketide synthase, KS-AT-KR-ACP domains
Genes
PRUE: LVJ94_06285
STRE: GZL_00801
SNR: SNOUR_03810
SNQ: CP978_03060
SYUN: MOV08_03325
AG: AAF71766(nysI) AAK73501(amphI)
Reference
PMID:11451671 (amphI)
  Authors
Caffrey P, Lynch S, Flood E, Finnan S, Oliynyk M
  Title
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.
  Journal
Chem Biol 8:713-23 (2001)
DOI:10.1016/S1074-5521(01)00046-1
  Sequence
[ag:AAK73501]
Reference
PMID:10873841 (nysI)
  Authors
Brautaset T, Sekurova ON, Sletta H, Ellingsen TE, StrLm AR, Valla S, Zotchev SB
  Title
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.
  Journal
Chem Biol 7:395-403 (2000)
DOI:10.1016/S1074-5521(00)00120-4
  Sequence
[ag:AAF71766]
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