Streptomyces sp. 769: GZL_00801 Help Entry GZL_00801         CDS       T03587                                  Name (GenBank) NysI   KO K16385   polyene macrolide polyketide synthase, KS-AT-KR-ACP domains Organism stre  Streptomyces sp. 769 Pathway stre01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:stre00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     GZL_00801  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:stre01008]     GZL_00801 Polyketide biosynthesis proteins [BR:stre01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Polyene macrolide PKS      GZL_00801 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C KAsynt_C_assoc PP-binding adh_short PKS_DE CurL-like_PKS_C Thiolase_N Epimerase adh_short_C2 PKS_DH_N RhiE-like_linker GDP_Man_Dehyd PS-DH Polysacc_synt_2 DUF7080 NmrA SDR 3Beta_HSD Docking Sacchrp_dh_NADP RmlD_sub_bind FAS_AT_central Motif Other DBs NCBI-ProteinID:  AJC53405 UniProt:  A0A0A8EBC2 LinkDB All DBs Position complement(892144..920715) Genome browser AA seq 9523 aa AA seqDB search MDNEQKLRDYLKLATADLRRTRRRVHELESAAQEPVAIIGMTCRYPGGVRSPEDLWRMVE AGKHGVTPFPTDRGWDLEALAAAPTASGGFLHDAPDFDADFFGISPREAVAMDPQQRVVL ESAWEAFERAGIDPTSVKGSRTGVFIGAMAQDYRVGPADGAEGFQLTGNTGSVLSGRISY TFGTVGPAVTVDTACSSSLVAVHLATQALRAGECTLALAGGVTIMSGPGTFIEMGRQGGL SADGRCRSFGDTADGTGWAEGVGILVLERLSDAVRNGHEILAVVRGTAVNQDGASNGLTA PNGPSQQQVIQQALVNARLAAGDIDVVEAHGTGTTLGDPVEAQALLATYGQNRPQDRPLL LGSVKSNLSHTQAAAGVAGVIKMVMAMRHGTLPRTLHAEEPTHHVDWSQGAVRLLTDTTD WPATGAPRRAAVSSFGISGTNAHTIIEQAPEPQPEDAATAQADDVADSTPTTAPVVPGVV PVLLSGRTPDALRGQAAALRAALGTGRRPDLLDLAHSLATTRAGFEHRAVLLATDHPALA DGLTALADAADPAAAPAWITDTTRAETRLAVLFTGQGAQRLGAGRELAARFPAFATALDA ALDAFTPHLDRPLREVLWGTDAALLDRTAYAQPALFAVEVALYRLIESFGVRPDHLAGHS VGEIVAAHLAGVLSLADAATLVAARGRLMQALPDGGAMIAVQASEADVAPLLAGHEDQVA IAAVNGPSAVVLSGAEATVTALAEQLAADGRKTRRLRVSHAFHSPLMEPMLDAFRAVVED LTLQPPLLPVVSNLTGKPATVAQLTSADYWVDHVRHAVRFADGIDWLARHDTTAFLELGP DGVLSAMAQDCLDAADAGAVTLPALRAGRPEEHTLTAALAGLHVHGTAVDWTGCFAGTGA RRADLPTYAFQRRRYWPKALQSGTADLRSVGLGAAHHPLLSAAVSLADAGGTLLTGRLSR QTHPWLADHTVRGTTLLPGTAFLELAVRAGDEVGCDRVEELTLAAPLLLPEQGGVQVQLW IGNPDASGRRTVNVHARPDTGDDTPWTAHATGVLTTADASPQLSASSEQGGTPLAGDPHP ALDAAQWPPAGAEPLPLDGHYDRLAEGGFGYGPVFQGLRAAWRSGDAVYAEVELPEAGRS DAEAFGLHPALLDAALHAAPFTGLGERGRGGLPFSWEGVALHAGGATTLRVRLTPVADDA LALTVADGTGAPVLSVDSLVLRSVATQQLDTAAVVARDALFRLDWTPVRPTATDPGPVAL LGADPFGLLTHAGFADATAYPDLAALAAADGPVPTTVVLSLAGTGDDAADPARSAHRCAA DALAAVQTWLDHHERFAAARLVFVTRGATVGRDVAGAAVWGLVRSAQSENPGCFGLVDLD PDGAVGAAVLVAALAGGEPQFAVRGGVLRVARLVRRPLTEGGEGTDDGSGVSFSGEGAVL VTGGTGGLGAVLARHLVAEYGVRDLLLVSRSGERAVGAGELVAELVGVGARVRVVACDVT DRAAVVELVAGHCVSAVVHAAGVLDDGMVGALTGERLSAVLRPKVDAAWHLHEATRGLDL EAFVVFSSLAGVFGSPGQANYAAANAFLDALMMQRRAEGLPGLSLAWGPWSLTGGTSGML ADAEAERLARSGVPPLSVAQGLALFDAAVAGTDATCVPVRLDLPALRARGEVPPLLRSLI RVRARRAAVAGSATAGNLAQRLRRLDQDGRDEMVLDLVRGQVALVLGHATGGDVDAGRAF RDLGFDSLTAVELRNRLNTVTGLRLPATMVFDYPTVRHLASYVLDELLGADAEVATVQRA AVAVADDPIVIVGMACRYPGGVSSPEDLWRVLTEGTDAVSGFPTNRGWDVESLYHPDPDH LGTSYTRSGGFLHEAGEFDPGFFGMSPREALATDSQQRLLLESSWEAIERAGIDPVSLRG SRTGVFAGVMYSDYSAMLAGPEFEGFQGSGSSPSLASGRVAYTLGLEGPAVTVDTACSSS LVAMHWAMQALRSGECGLALAGGVTVMSTPAVFVDFARQRGLSPDGRCKAFADAADGVGW SEGVGVLVLERQSDAVRNGHEILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASGG LSTTDVDAVEAHGTGTTLGDPIEAQALLATYGQDREQEHPLLLGSVKSNLGHTQAAAGVA GVIKMVLAMRHGVLPRTLHVDAPSSHVDWSEGAVELLSEQAAWPETGRVRRAGVSSFGIS GTNAHVIVEQAPGAKAIAAAGAARRTPGAVPVLLSGRGRSALRSQAARLLGHLQARPDAE LVDVALSLATIRSRFEQRAAVVAQDRDQLIASLGALATDRPDPAVVEGEAAGRGRTAVLF TGQGSQRAAMGRELHEAQPQFAAAFDAVCAALDPLLDRPLREVVFAEDGSDEAALLDETG WTQPALFAVEVALFRLVESWGVRPDFVAGHSIGEIAAAHVAGVLTLEDACRLVAARATLM QALPTGGAMIAVQATEDEIAAHLDDTVAIAAVNGPQSVVISGDEEAAGTIAATFAERGRK TKRLRVSHAFHSPRMDGMLDAFRIVAEGLTYRAPRIPLVSDLTGRRADDAEVCTAEYWVR HVREAVRFADCVRTLRDAGATTFLELGPDGLLTAMAEDTLGDDHDVELVPILRAGRAEEL AAATALARLQVRGVDVDWAAYLAGTGARRTDLPTYAFQHAYYWPQLPAPAAALAADPADQ QLWAAVERGDARELADILGLGEQDLTPLDSLLPALTSWRRGNQEKHLLDTLRYRVEWTRL SKPAAPVLDGTWLLVASDATAADQAALLDGLADALGSHGARVRRLLLDDSCADRAVLAER LARTADVDAATQVLSVLPLDERDADDCPPLTRGLALTVALVQALADTGAQGRLWTATRGA VSIGPADPVTHPVQAAAWGLGRGVALELPRLWGGLVDLPEVFDERAGQRLAGILAVKDVP DGEDQVALRATGVSGRRLVRHTVEALPTAAEFTAAGTVLITGGTGGLGAEVARWLARAGA QHLVLTSRSGPDAPGAAELRAELEGYGPSVSVVACDVADRDALAAVLAALPEAALPEKLP LTGVVHTAGVGHYGPLDTLSTAEFAGLTAAKLAGAAHLDALLADRELDFFVLFGSIAGVW GSGNQSAYGAANAYLDALALHRRSRGLAATSVAWGPWAEAGMAADDAVSATLRRQGLGLL DPAPAMTELRRAVVRQDVNVTVADVDWQRYAPLFTSARPSALIAGLPEVRALAADERTEQ DAADASEVVTRVRALAEPEQLRLLTDLVRTESATVLGHSSADAVPEGRAFRDVGFDSLTA VELRKRLGAATGLSLPSTMVFDYPTPLELAQYLRAEILGAVLEVAGPVATGGADDEPIAI IGMACRFPGGVSSPEQLWDLVASGTDAISEFPVNRGWHTGHLFDPDPDRPGTTYSTQGGF LHEADEFDPTFFGISPREALVMDPQQRLLLETTWESFERAGIRPETLRSTLTGTFVGSSY QEYGLGAGDGTEGHMVTGSSPSVLSGRLSYVFGLEGPAVTVDTACSSSLVALHLACQSLR NGESNLAVAGGATIMTTPNPFIAFSRQRALAKDGRCKAFSDDADGMTLAEGVGVVLVERL SDAQRNGHPILAVLRGSAINQDGASNGLTAPNGPSQQRVIRQALANARLAPGDIDALEAH GTGTPLGDPIEAQALFATYGRDRDPESALLLGSVKSNIGHTQSAAGIAGVIKMVMALRHS ELPPTLHADAPSSHVDWSAGTVRLLTQARAWPETGRPRRAAVSSFGISGTNAHVLLEQAP VADTPAQERPAVAPVPIAAGVVPWVVTARSAAALRGQADRLLAYAETAETALPAAGPLDI GLSLVSARARFEHRAVVVPPAGTDPLAALRAVATDGPSPVVARGVADVEGRTVFVFPGQG SQWVGMGARLLDESPVFAERIGECAAALAEFADWSLVDVLRGGVGAPSLERVDVVQPASF AVMVSLAALWRDRGVEPDAVVGHSQGEIAAAVVSGGLSLRDGARVVALRSQAIGRALAGR GGMMSVALSVEALEPRLEGFEGRVSVAAVNGPRSVVVAGEPEALDALHARLAADEIRARR IAVDYASHSHQVEDLHEELLEVLAELAPRTSEVPFFSTVTGDWLDTAQMDAGYWFRNLRG RVRFADAVADLLAAEYRVFVEVSSHPVLSMAVQEAIDEAGVPAVAAGTLRRDQGGTDRFL LSAAEVFVRGVDVDWAGLFEGTGASRIDLPTYAFQHEHLWAVPPAPEAVAAADPDDAEFW AAVEQADVSALTAALGTDEDSVAAVLPALSSWRRARRDRSTVDAWRYRVAWKPLGGTLPH PSMTGTWLLVTADGIDDTDVAGALETYGAEVRRLVLDEECVDRVVLRERLAGVEDVTGIV SVLAAAERTDAVPGTSLVLGTALTVALIQALGDAEIDAPVWALTRGAVSTGRADELTAPV QAQVTGIGWTAALEHPQRWGGTLDLPAALDARAAQRLAAVLSGALGGDDQLAIRPSGVFT RRIVRAEATAGRPAGTWTPRGTTLVTGGSGTLAPHLARWLAERGAEHLVLISRRGTAAPG AAELVAELAESGTEATVAACDITDRDAVAALLADLKADGRTVRTVVHTAATIELHTLDAT TLADFDRVLHAKVTGAQVLAELLDDEELDDFVLYSSTAGMWGSGAHAAYVAGNAYLAALA EHRRARGLPALSLSWGIWADDLKLGRVDPQMIRRSGLEFMDPQLALSGLQRALDDNENVL AVADVDWETYHPVYTSGRPTPLFDEVPEVRRLTAAAEQSAGTVAEGEFAAALRALSDAEQ QRTLLETVRTEAASVLGLSSAEDLTDQRAFRDVGFDSLTAVGLRNRLASVTGLTLPSTMV FDYPNPAALAAYLHGELAGARTAAGAVAVPTSAPAADDPIAIVGMSCRYPGGVGSAEDLW RIALDEVDAISGFPADRGWDAEGLYDPDPDRPGRTYSVQGGFLRNVAEFDPGFFGISPRE ALSMDPQQRLLLETAWEAFEHAGIDPVAQRGSRTGTFVGASYQDYASSVPNSEGSEGHMI TGTLSSVLSGRVSYLFGFEGPAVTLDTACSSSLVAMHLACQSLRNGESSLALAGGVSIMS TPMSFVGFSRQRALAEDGRCKAYADGADGMTLAEGVGLVLLERLSDARANGHQVLAVIRG SAVNQDGASNGLTAPNGPSQQRVIRQALANSAVAPGDIDVLEGHGTGTALGDPIEAQALL ATYGQDRAPERPLLLGSVKSNIGHTQMASGVASVIKLVRALQEGVVPKSLHIDRPTTHVD WSSGAIGLLTERTPWPETGRPRRAAVSSFGISGTNVHTILEQAPADEAPAPADPPRDGLV PVLLSGRGEAALRAQAARLLAFVEERPEAHLTDLAHSLATSRAALERRAAVIAADRDTLT RGLRALSYGRPDPGLVQGTAGRGRTAFLFTGQGSQRAGMGRELHDRHPVFADALDEVLAR LDDGPDRPLREVLFAAPDSAEAALLDRTGYAQPALFAVEVALFRLLASWGLAPDYLAGHS VGEIAAAHVAGVLSLDDACTLVAARGRLMQALPEGGAMVALEAAEDEVLPLLEGLTDRVS VAAVNGPRSVVVAGVEEDVLLLADLFAADGRRTKRLRVSHAFHSPLMDAMLDDFAAVARG LTYHPPTIPFVSNVSGGLATAEQVCTPDYWVGHVRAAVRFADGIDWLATQGDVHTFLELG PDGVLSGMARENLTDPSRTALLPTLRGDRPEEPALVTAVAAAHAHGARVDWSGYFADHGA RRTTLPTYAFQRERYWPDTTAAAATARTPGSALDAEFWAAVERDDVAALAASLDLDDATV TAMVPALTAWRRRRGEQSELDSWRYRVTWKPRGGATAPAALTGRWLVLVPHDHQDRQDAE TAAWAADVETALGTTTVRLPVTTTDRAALAARITEVAGTQGPFSGVLSLLPLATGDAGHP GAPAALTLTTTAVQALGDAGIDAPLWNVTRGAVAVGRAEQVTAPEQAAVWGLGRAVALEL PARFGGTLDLPATLDGQAARRLRAVLAATDGEDAVALRPSGVFLRRLAHAPAGPDTARTA FDPAAGTVLITGGTGGIGGHVARRLARDGATHLLLTSRRGPAAPGADALRAELEELGARV TLAACDAADRDALAALLAELPDDAPLCAVFHTAGVVEDHVVDALTPESFAAVLRAKTVAA HHLHELTADLDLAAFVLFSSTAGVLGAAGQGNYAAANAHLDALAEHRRSRGLTALSVAWG PWAGSGMVADTAELTDRVRRGGFEPLAPEPAVRALLRAIENDDTTVALADIDWERFQRAF AAVRPLPFVADLPETGRATAATATGAATGLRQRLAELPEHERPAAVLDLLRTQVAAVLGH ADPRTVEDDHAFRDLGFDSLTILELRNALNAATGLSLPATLVYDLPTPREMADFLLAELL GTLPTDTAAIVATTSPKLSASFEQGGTPFDDDPIAVIGIGCRFPGGVTTPEELWQLLDEG RDGISRFPDDRGWDLAALGAGASDTLEGGFLSGVADFDARFFGISPREALAMDPQQRLLL ETTWEALERAGIDPAALRGSTTGVFVGTNGQDYPTLLRRSASDVAGYVATGNTASVMSGR LSYALGLEGPAVTIDTACSSSLVALHWAGRALRAGECDLVVAGGVSVMASPDSFVEFSTQ GGLAPDGRCKAFSDAADGTAWSEGVGILVLERLSAARRNGHQVLGLIRGTAVNQDGASNG LTAPNGLSQQRVIAQALADARLRPADIDAIEAHGTGTTLGDPIEARALITAYGRDRDAER PLLLGTVKSNIGHTQAAAGAAGVIKMLMAMRHGTLPRTLHVGTPSSHVDWSGGTVALLDD ARPWPQTGQPRRAGVSAFGVSGTNAHVVVEQAPEPEAPAADAPAAEPAPEATPTVVPWIV SGRSREALQAQLDRLTAHTAAHPARSAADVGRSLATDRTLFPHRAVLLAGPDGVREAARA TAPRTPGRTAFLFSGQGAQHALMGHDLYQRFPVYADALDTVLAQFDTVLDVPLRAALFAA PGTPEAALLDQTGFTQPALFAVEVALFRLAESWRLTPDFVAGHSIGEIAAAHVAGVFSLE DACTLVAARASLMQQLPQDGAMVALEATEDEVAPLLTDGVAVAAVNGPRSVVVAGAEDAV RAVADRLAADGRRTRRLTVSHAFHSPLMDPMLTEFARAAEGLTYHEPRIPLVSTLLGAPA GAELRTPGYWVRHVRETVRFADGVRALHDAGAGTFVEIGPDGVLAALTQQTLDTVEAGAP AVVVPLQRRDRAGDLALLEGLATLHTHGTGPSWPAYFEATGGHRTDLPTYAFQRERYWPE PGAPADAPQDPADAAFWTAVERADLEGLAASLGLDGDTVTAMVPALSAWRRRQGARSAAA QWRYHETWAPLPAPETTAPAGRALVLVPAGNRDTAWMTAVADALGDTVTTEPDALAEQLT AAGDTPWRVVVSLLAAASEELPADGAWPAALLATLDEAGVHAPLWCVTRGAVAVAGEPPT AVGQAALWGLGRVAALDHPDRFGGLADLPADTDAHAAGLLAAHLAAPGTEAEIAVRATGI HARRLVRMPAAADGATWLPTGTVVVVGGTGTMGGRAARWLAREGARHLVLTAPGDNTTSD DNTTTEALTAELAAFGARITVVDHDPTAPDGFAALLDGLPDDTPLTAVVYAPEADATPDT AAELSAALAPVTALGAALTGRPLDAFVLFGSIAGVWGVRGRAAEAASGAYLDAFARACRD RGTPALAVAWGAWSGLADRSLAAHLRMNGLPVMDADTALAALGRAVADGSAAETVADVRW ETFAPLHHEARRTALFDALPEARGALAEAARDRADRQTAAGDYGRWLAEQPAADHDAVLL ALVTEKAATVLGHADHDLLEPDLPFRDLGFDSLTAVDLRNQLTAETGLALPATLVFDHPN PAALAAHLRAQLLGEAVDSAAPVAAPVASGADDDAIVIVGMACRYPGGVTSPEDLWQLVG DEIDAVGDFPTDRGWDLAALAGDGPGRSATAQGGFLYDATDFDPGLFGISPREALVMDPQ QRILLETSWEALERAGIDPATLRGSGTTGVFVGGGSGDYRPPEEAGQWQTAQSASLLSGR LAYTFGIQGPTVSVDTACSSSLVALHLAAQALRAGECSIALAGGVTVMATPVGFVEFSAQ GALSPDGRCRAFSDDANGTGWSEGVGMLVVERLSDARRNGHRVLAVLRGSAINQDGASNG LTAPSGPAQQRVIRQALANARLRPADIDAVEAHGTGTKLGDPIEAQALLATYGQDRERPV LLGSLKSNIGHTQAASGVGGVIKMVLAMQHGELPRSLYAENPSSHVDWAAGRAHLLTART PWPDSGRPRRAAVSSFGASGTNAHAILEQPPREELPARPADDGAPLPFLLSGRSQNALRA QARRLLARLTARPDTRTADLAYSLATTRAAFEHRAAITATDHDGLRTGLTAVAEGTTAPH TAEHHLQRTGKRAVLFSGQGSQRLGMGRELYERHPVFAEAFDAVLARLDDRLDTPLRDVV WGTDEEALHATGNTQPALFAVEVALYRLIESWGVRPDFVAGHSVGELAAAHVAGVLSLDD ACRLVAARAALMQRLPAGGAMIAVEATEDEVTPLLTDGVSLAAVNGPTAVVLSGAGDAVT ALAETLAERGHRTTRLRVSHAFHSHLMDPMLADFRTVAEGLEYHPPRIPVVSNLTGDVAD AADLCSADYWVRHVRGTVRFADGVRTMADRGVHLFLELGPDAVLSAMARQCAPDAVVVPA LRRTRGEDETLVGAVAHLHVHGAGPRWDAYFAGRGAQWLDLPTYPFQRGRFWPESLPGAA SVAPAAGQPAETDAAFWDAVAQEDFTALESVLDVESDALSKVLPALMDWRSRQADESQLV SWRHRIVWKRLTGAALAHRKALSGTWLAVVPEGLADDPWVTTTLDGLGTHLVRLEVAEAD RAALADAIAARTADGTRFGGVVSLLALRDTLTGAVPEGTALTTVLLQALGDAGVDAPLWC VTRSAVSAGRTDRPHRPLQGAVWGLGRVAALEHPQRWGGLVDLPEEPDERSAAGLAAVLA GLDGEDQVAVRGTAVLARRLVPAPGRKSSRPWHPSGTVLVTGGTGALGAHVARRLAKDGA QHLVLLSRRGPDAPGAAELRAELDALGTGVTVAACDVADRDQLTAALDALPADRPLTGVV HTAGVLDDGVLDRLTPERFQEVFRAKVTSALLLDELTRDRELAAFVLFSSASAAVGNPGQ ANYAAANAVLDALAEQRRVLGLPATSVSWGAWGGGGMADADGADEAARRAGVGAMDPHLA VEALLRLVAEKEPTAVVAEVALDRFAGAFGGSRPSALLREFPGYREALAAQAEQAADGGG LAARLAALPPARRLDTVVDLVRTRAAQVLGYPDTEAVAAERSFRDLGVDSLGAVELRNQL SAATGLNLPATLVFDHPTPLALGEHILGGLFPDEPAGSDDETEIRALLASVPLDQLREIG VLEPLLQLAGRGGRAADDDDGESVDSMTVADLVRAALNGQSDL NT seq 28572 nt NT seq  +upstreamnt  +downstreamnt atggacaacgaacaaaaactccgggattacctcaagcttgcgacggccgaccttcgacgc acccggcggcgcgtccacgagctggagtcggcggcccaggaaccggtggccatcatcggc atgacctgtcgctaccccggaggcgtccgcagccccgaagacctctggcgcatggtcgag gccggcaagcacggcgtcaccccgttccccaccgaccgcggttgggacctggaggcgctg gccgccgcgccgaccgcctccggcggattcctgcacgacgcacccgacttcgacgcggac ttcttcggcatctcgccgcgcgaggcggtcgccatggacccgcaacagcgcgtcgtcctg gaatccgcctgggaggcgttcgaacgcgccggcatcgacccgacgtccgtgaagggcagc cgcaccggagtcttcatcggcgcgatggcccaggactaccgcgtcggccccgccgacggc gccgagggcttccaactcaccggcaacaccggcagcgtgctgtccggccgcatctcctac accttcggcacggtcggccccgccgtcaccgtcgacaccgcctgctcctcctccctggtc gccgtccacctcgccacccaggcgctgcgggccggcgagtgcaccctcgccctcgccggc ggcgtcaccatcatgtccggccccggcaccttcatcgagatgggccgccagggcgggctc tccgccgacggccgctgccgctccttcggcgacaccgccgacggcaccggctgggccgaa ggcgtcggcatcctcgtcctggaacggctctccgacgccgtccgcaacggccacgagatc ctcgccgtcgtccgcggcaccgccgtcaaccaggacggcgcctccaacggcctgaccgcc cccaacggcccctcccagcagcaggtcatccagcaggccctggtcaacgcccgactcgcc gccggggacatcgacgtcgtcgaggcgcacggcaccggcaccaccctcggcgaccccgtc gaggcccaggccctgctcgccacctacgggcagaaccgcccgcaggaccggccgctgctg ctcggctcggtcaagtccaacctcagccacacccaggccgccgccggcgtcgccggcgtg atcaagatggtcatggcgatgcggcacggcaccctgccgcgcaccctgcacgccgaggag cccacccaccacgtcgactggtcgcagggcgccgtgcggctgctgaccgacaccaccgac tggcccgccaccggggcaccgcgccgcgccgccgtctcctccttcggcatcagcggcacc aacgcccacaccatcatcgagcaggcccccgaaccgcagcccgaggacgccgcgaccgcg caggccgacgacgtcgccgacagcacgccgaccaccgcccccgtggtgcccggcgtcgta ccggtcctgctctccggccgcaccccggacgccctgcgcggccaggccgcggccctgcgc gccgccctcggcaccggccggcggcccgacctgctcgacctcgcacactccctcgccacc acccgcgccgggttcgagcaccgcgccgtcctcctcgccaccgaccaccccgccctggcc gacggcctcaccgccctcgccgacgccgccgacccggccgccgcccccgcctggatcacc gacaccacccgggccgagacccggctcgccgtcctcttcaccggccagggcgcccaacgc ctcggcgcgggacgggaactcgccgcccgcttcccggcgttcgccaccgccctcgacgcg gcgctcgacgccttcaccccgcacctcgaccgccccctgcgcgaggtcctgtggggcacc gacgccgccctgctcgaccgcaccgcatacgcccagccggccctcttcgccgtcgaagtg gcgctctaccggctgatcgaatcgttcggcgtccgccccgaccacctcgccggccactcc gtcggcgagatcgtcgccgcgcacctcgccggcgtcctctccctggccgacgccgccacc ctcgtcgccgcccgcggtcgcctgatgcaggcgctgcccgacggcggcgcgatgatcgcc gtccaggcatcggaagccgacgtcgccccgctgctcgccgggcacgaggaccaggtcgcg atcgccgccgtcaacggcccctccgccgtcgtcctctccggcgccgaagccaccgtcacc gcgctcgccgaacagctcgccgccgacggccgcaagacccgccggctgcgcgtctcgcac gccttccactcgccgctcatggagccgatgctcgacgccttccgcgccgtcgtcgaggac ctcacgctccagccgccgctgctgccggtcgtctccaacctgaccggcaagcccgccacc gtcgcccaactcacctccgccgactactgggtcgaccacgtccggcacgccgtccgcttc gccgacggcatcgactggctcgcccggcacgacaccaccgccttcctcgaactcggcccc gacggcgtgctgtccgccatggcccaggactgcctggacgccgccgacgcaggtgccgtc accctccccgccctgcgcgccgggcgccccgaggagcacaccctcaccgccgccctcgcc ggcctgcacgtccacggcaccgccgtggactggaccggctgcttcgccggcaccggcgcc cgccgcgccgacctgccgacctacgccttccagcgccgccgctactggcccaaggccctc cagagcggcaccgccgacctgcgctcggtcggcctcggcgccgcccaccacccgctgctc tccgccgccgtctccctcgccgacgccggcggcaccctgctcaccggccgcctctcccgg cagacccacccctggctcgccgaccacaccgtccgtggcaccaccctgctgcccggtacc gccttcctcgaactcgccgtccgcgccggcgacgaggtcggctgcgaccgcgtcgaggaa ctcaccctcgccgcaccgctcctgctgcccgaacagggcggcgtccaggtccagttgtgg atcggcaaccccgacgcttccggtcgccgcaccgtcaacgtgcacgcccgccccgacacc ggcgacgacaccccctggaccgcccacgccaccggcgtcctcaccaccgccgacgcctcc ccccagctctcggcctcgtccgagcagggcggcacccccctcgccggcgacccccacccc gccctcgacgcggcccagtggcccccggccggcgctgaaccgctgccgctggacggccac tacgaccgcctcgccgagggcggtttcggctacggcccggtcttccagggcctgcgcgcc gcctggcgcagcggcgacgccgtctacgccgaggtcgagctgcccgaagccggccggtcc gacgccgaggcgttcggcctccaccccgccctgctcgacgccgccctgcacgccgcgccc ttcaccggcctcggcgaacgcggccgcggcggcctgccgttctcctgggagggcgtcgcc ctccacgccggcggtgccaccaccctccgggtccgcctgaccccggtcgccgacgacgcg ctcgccctgaccgtcgccgacggcaccggtgcgcccgtgctgtccgtcgactcgctcgtc ctgcgcagcgtggcgacccaacagctcgacacggccgccgtcgtcgcccgtgacgccctc ttccgcctcgactggacccccgtccggccgaccgccaccgaccccgggcccgtcgccctc ctcggcgccgaccccttcggcctgctcacccacgccgggttcgccgacgccacggcatac ccggacctcgccgccctcgccgcggcggacggcccggtcccgaccaccgtcgtgctgtcc ctcgccggcaccggcgacgacgcggccgacccggcccggtccgcacaccgctgcgccgcg gacgccctcgccgccgtgcagacctggctcgaccaccatgagcgcttcgccgccgcccgc ctggtcttcgtgacccgtggtgcgacggtcgggcgtgatgtggctggtgctgcggtgtgg ggtctggtgcgttcggcgcagtcggagaatccgggttgttttggtctggtcgatctggat ccggatggtgcggtgggtgcggcggtgctcgtcgctgcgttggctggtggtgagccgcag tttgcggtgcggggtggtgtgttgcgggttgcgcgtctggtgcggcggccgctcaccgag gggggtgagggcactgatgacggctctggtgtgtcgttctcgggtgagggtgcggttctg gtcacgggtggtacgggtggtctgggtgcggtgttggcgcgtcatctggtggccgagtac ggggtgcgggatctgctgttggtcagtcgcagtggtgaacgtgcggtgggtgctggggag ttggtggcggagcttgtgggtgtgggtgcgcgggtgcgggtggttgcgtgtgatgtgacc gatcgtgccgcggtggtggagttggttgccgggcattgtgtgtctgcggtggttcatgcg gcgggtgtgctggatgacggcatggtgggtgcgttgaccggggagcggttgtccgcggtc ctgcggccgaaggtggatgctgcctggcatctgcacgaggcgacccgcggcctggacctg gaggcgttcgtcgtcttctcctccctcgccggtgtcttcggcagccccggccaggccaac tacgcggcggcgaacgccttcctggacgcgctgatgatgcagcgccgggcggagggtctg cccggcctgtcactggcctggggaccgtggtcgctgaccggtggcacatcgggcatgctc gcggacgccgaggccgaacgtctggcccgctccggtgtcccgccgctctccgtggcgcag ggcctggccctcttcgacgctgccgtggccgggaccgacgccacctgcgtgccggtccgc ctggacctccccgccctccgcgcacggggtgaagtgccgccgctgctacggtcgttgatc cgcgtccgggcgcgccgcgccgccgtcgccggctccgccaccgcgggcaacctcgcccag cgcctgcgccgcctggaccaggacggccgcgacgagatggtcctggacctcgtccgcggc caggtcgccctcgtcctcggccacgcgaccggtggcgacgtcgacgccggccgtgccttc cgcgacctcggcttcgactcgctgaccgccgtcgaactgcgcaaccgcctcaacaccgtc accggcctgcggctccccgcgaccatggtgttcgactatccgaccgtccggcacctcgcc agctacgtcctggacgagttgttgggcgcggatgccgaggtggcgaccgtgcagcgggcc gcggtggcggtggcggacgacccgatcgtcatcgtgggcatggcctgccgctaccccggt ggcgtcagctcccccgaggacctgtggcgcgtgctcaccgaaggcaccgacgccgtctcg ggcttcccgacaaaccgtggttgggacgtcgagtccctctaccacccggaccctgaccat ctcggtacctcttacacccgctcgggtgggttcctgcatgaggcgggggagttcgatccg gggttcttcgggatgagtccgcgtgaggcgttggcgaccgactctcagcagcggttgttg ttggagtcgtcgtgggaggcgattgagcgggccggtattgatccggtgagtttgcggggc agtcggacgggtgtgttcgcgggggtgatgtacagcgattacagcgcgatgttggccggt ccggagttcgagggtttccagggcagtggtagttcgccgagtttggcgtcgggtcgggtg gcctacacgttgggtcttgagggtccggcggtgacggtggatacggcgtgttcgtcgtcg ttggtggcgatgcactgggcgatgcaggcgttgcgcagtggtgagtgtgggttggcgttg gccggtggtgtgacggtgatgtcgacgcctgcggtgtttgtggactttgctcggcagcgg ggtctgtcgccggacggtcggtgcaaggcgttcgcggatgcggccgatggtgtgggctgg tccgagggcgtgggtgtgttggtgttggaacgtcagtcggatgcggtgcgcaacggtcat gagatcctggccgtggtgcgcggttcggcggtcaaccaggacggtgcgtccaacggcctg accgcgccgaacggtccgtcccagcagcgcgtgatccgtcaggcgctggccagcggcggc ctgtccacgaccgatgtcgacgcggtcgaggcccatggcacgggcaccacactgggcgac ccgatcgaggcccaggcactcctcgccacctacggccaggaccgcgaacaggaacacccg ctgctgctcggctcggtcaagtccaacctcggccacacccaggcggctgccggtgtcgcc ggcgtcatcaagatggtgctggcgatgcggcacggcgtgctgccgcggacgctgcatgtg gatgcgccttcctcgcatgtggactggtccgagggtgcggtggagctgctgagcgagcag gctgcctggccggagacgggtcgggtgcggcgggccggtgtctcctcgttcggcatcagc ggcaccaacgcgcacgtcatcgtcgagcaggcaccgggcgccaaggcgatcgccgcggcc ggtgcggcgcggcgcacgccgggtgccgtgccggtgctgctctcggggcgtggccggagt gccctgcggagccaggccgcccggctgctcggacacctccaggcccgacccgacgccgaa ctcgtcgatgtcgcactgtccttggccaccatccggtcccgcttcgagcagcgggccgcc gtcgtggcgcaggaccgcgaccagctgatcgcctcgctgggggcgctggccaccgaccgc ccggaccctgccgtcgtcgagggcgaggccgccggacgcggccggaccgcggtgctgttc accggacagggcagccagcgggccgccatggggcgtgaactccacgaggcacagccgcag ttcgccgcggcgttcgacgcggtgtgtgccgcgctcgacccgctgttggaccgaccgctg cgcgaggtggtgttcgccgaggacggcagcgacgaggccgcactgctggacgagaccggg tggacccagcccgctctcttcgccgtcgaggtggcgctgttccggctcgtggagagctgg ggcgtccgtccggacttcgtggccggccactccatcggtgagatcgcggcggcgcacgtc gccggggtactgacgttggaggacgcctgccgcctggtggccgcgcgggcgacgctgatg caggcgctgcccaccggcggcgcgatgatcgcggtccaggcgaccgaggacgagatcgcg gcgcacctcgacgacacggtggcgatcgccgccgtcaacgggccgcagtccgtggtgatc tccggcgacgaggaggcggccgggacgatcgccgccacgttcgccgaacgcgggcgcaag accaagcggctgcgggtgagccatgccttccactcgccccggatggacgggatgctggac gccttccggatcgtcgccgaggggctgacctaccgggcgccgcgcatcccgctcgtctcc gacctcaccggtcggcgcgccgacgacgcggaggtgtgcaccgcggagtactgggtgcgg cacgtccgcgaggccgtgcggttcgccgactgcgtgcggacgctgcgcgacgccggagcc accaccttcctggaactgggccccgacggcctgctgaccgcgatggccgaggacaccctc ggcgacgaccacgacgtcgaactggtgccgatcctgcgcgccgggcgcgccgaggaactt gccgcggccaccgccctggcccgcctccaggtgcgcggcgtggacgtggactgggcggcg tacctcgccggcaccggcgcccggcgcaccgacctgccgacctacgccttccagcacgcg tactactggccgcagctgccggccccggccgccgccctcgccgccgaccccgccgaccag cagctgtgggccgccgtggagcgcggcgacgcccgcgaactcgccgacatcctcggcctg ggcgagcaggacctcacaccgctggactccctgctgcccgccctcacctcatggcggcgc ggcaaccaggagaagcacctcctggacaccctgcgctaccgcgtggagtggacgcgactg agcaagccggccgccccggtcctcgacggcacctggctgctggtcgcctccgacgccacc gcggccgaccaggcagccctcctcgacggcctggccgacgccctcggctcgcacggcgcg cgggtgcgtcgcctgctcctggacgactcctgcgcggaccgcgcggtgctcgccgaacgg ctggcacggaccgccgacgtggacgccgcgacccaggtgctgtccgtgctgccgctcgac gagcgggacgccgacgactgcccgccgctcacccgcggactggcgctgaccgtcgcgctc gtccaggccctcgccgacaccggcgcccagggccggctgtggaccgccacccgcggcgcc gtctccatcggccccgccgacccggtcacccaccccgtccaggccgccgcctggggcctg ggccggggcgtcgccctggagctcccgcggctgtggggcggcctggtcgacctgccggag gtcttcgacgagcgggccggacagcggctcgccgggatcctcgccgtcaaggacgtaccg gacggcgaggaccaggtggcgctgcgggccaccggagtgtccggccgccggctcgtccgc cacaccgtcgaagcgctgcccacggccgcggagttcaccgccgccggcaccgtcctgatc accggtggcaccggtggcctgggcgccgaggtcgcccggtggctggcccgcgccggcgcc cagcacctcgtcctgaccagccgcagcggcccggacgcgccgggcgccgcggaactccgg gccgaactggagggctacgggccgtcggtgtccgtcgtcgcctgcgacgtcgccgaccgg gacgcgctcgccgcggtcctcgccgcactgcccgaggccgcactgcctgagaagctgccg ctgaccggtgtcgtgcacaccgcaggcgtcggccactacggcccgctggacaccctgagc accgccgagttcgccggcctcaccgccgccaagctcgccggcgccgcccacctcgacgcc ctgctcgccgaccgcgaactggacttcttcgtcctcttcggctccatcgccggtgtctgg ggcagcggcaaccagagcgcctacggcgccgccaacgcctacctcgacgcgctcgccctg caccgccgctcccgcggcctcgccgcgacctccgtcgcctggggcccgtgggccgaggcc ggcatggccgccgacgacgcggtctccgcgaccctgcgccgccagggcctcggcctgctc gacccggccccggccatgaccgagctgcgccgcgccgtcgtccggcaggacgtcaacgtc accgtcgccgacgtcgactggcagcgctacgcaccgctgttcacctccgcccggcccagc gccctgatcgccggcctgcccgaggtccgcgccctcgccgccgacgagcgcaccgagcag gacgccgccgacgcctccgaggtcgtcacccgcgtccgcgccctggccgaacccgagcaa ctgcgcctgctgaccgacctcgtccgcaccgagtccgccaccgtcctcggccacagctcc gccgacgccgtccccgagggccgcgccttccgcgacgtcggcttcgactcgctgaccgcg gtcgaactccgcaagcgcctgggcgccgcgaccgggctgtccctgcccagcaccatggtc ttcgactacccgacaccgctggaactcgcccagtacctgcgggcggagatcctcggcgcg gtgctggaagtcgccggcccggtcgccaccggcggcgccgacgacgagccgatcgccatc atcggcatggcctgccgcttccccggcggcgtcagctccccggaacagctgtgggacctg gtcgcctccggtaccgacgcgatcagcgagttccccgtcaaccgcggctggcacaccggg cacctcttcgacccggaccccgaccggcccggcaccacctactccacccagggcggcttc ctccacgaggccgacgagttcgaccccaccttcttcggcatctcgccccgcgaggcgctg gtcatggacccgcagcagcggctcctgctggagaccacctgggagtcattcgagcgcgcc gggatccgtccggaaaccctccggtccaccctgaccggcaccttcgtcggctccagctac caggagtacggcctgggcgcgggcgacggcaccgagggccacatggtcaccggcagcagc cccagcgtgctctccggccggctgtcgtacgtcttcggtctggaaggcccggcggtcacc gtcgacaccgcctgctcgtcctcgctcgtggcgctgcacctggcctgccagtcgctgcgc aacggcgagagcaacctggccgtcgccggcggcgcgacgatcatgacgacgcccaacccg ttcatcgcgttcagccggcagcgcgccctcgccaaggacggccgctgcaaggcgttctcc gacgacgcggacggcatgacgctcgccgagggcgtcggcgtcgtcctcgtcgagcggctc tccgacgcgcagcgcaacggccacccgatcctggccgtcctccgcggctccgccatcaac caggacggcgcctccaacggcctgaccgcgcccaacggcccgtcccagcaacgcgtcatc cgccaggccctcgccaacgcccgcctcgcgcccggggacatcgacgccctggaggcgcac ggcaccggcacaccgctcggcgaccccatcgaggcccaggcactgttcgccacctacggc cgcgaccgcgaccccgagagcgcgctgctgctcggctcggtgaagtccaacatcggccac acccagtccgccgcgggcatcgccggcgtcatcaagatggtcatggcgctgcgccactcc gaactgccgccgaccctgcacgccgacgcgccgtcctcgcacgtggactggtcggccggg acggtccggctgctgacccaggcgcgcgcctggccggagaccggtcgcccgcgccgggcc gcggtgtcctcgttcggcatcagcggcaccaacgcccatgtcctgctggagcaggcgccc gtcgcggacaccccggcccaggagcggcccgccgtggcaccggtcccgatcgccgccggc gtcgtcccgtgggtggtcaccgcccgcagcgccgccgccctgcgcggccaggccgaccgc ctcctcgcgtacgccgaaaccgccgaaaccgcgctgccggccgccggaccgctcgacatc ggcctgtcgctggtctccgcgcgcgcccgcttcgagcaccgggccgtcgtcgtcccgccc gcgggcaccgacccgctggccgcgctgcgcgccgtcgccacggacgggccctcacccgtg gtcgcccgtggcgtggcggacgtcgagggtcggacggtgttcgtgttccccggtcagggt tcgcagtgggtggggatgggtgcgcggctgctggatgagtcgccggtgttcgcggagcgg attggggagtgtgcggcggcgttggcggagttcgccgattggtcgctggtggatgtgttg cgtggtggtgtgggtgcgccgtcgttggagcgggttgatgtggtgcagccggcgtcgttt gcggtgatggtgtcgttggctgcgttgtggcgtgatcgtggtgtcgagccggatgcggtg gtggggcattcgcagggtgagattgctgctgcggtggtgtcgggtgggttgtcgttgcgg gacggggcgcgggtggtggcgctgcggagtcaggcgatcggtcgtgcgttggcggggcgg ggcgggatgatgtccgtcgcgttgtcggtggaggcgctcgaaccgcggttggagggcttc gaggggcgggtgtcggtggccgccgtcaacggcccgcggtccgtcgtggtcgccggcgag cccgaggcgctggacgcgctgcacgcccggctggccgccgacgagatccgggcccgccgg atcgcggtggactacgcctcgcactcgcaccaggtcgaggacctgcacgaggaactgctg gaggtgctggcggagctggcgccgcgcacgtcggaggtgccgttcttctcgaccgtgacc ggcgactggctggacaccgcgcagatggacgccggctactggttccgcaacctgcgcggc cgggtgcggttcgcggacgcggtggccgacctgctggcggcggagtaccgggtgttcgtc gaggtcagctcgcacccggtgctgtcgatggcggtccaggaggcgatcgacgaggccggc gtgccggccgtcgccgccggcaccctgcgccgcgaccagggcggcaccgaccgcttcctg ctgtcggccgccgaggtcttcgtgcgcggtgtggacgtggactgggcggggctgttcgag gggaccggtgcgtcccggatcgacctgcccacctacgccttccagcacgaacacctgtgg gccgtcccgcccgccccggaggccgtcgccgccgccgacccggacgacgccgaattctgg gccgccgtcgagcaggcggacgtctccgcgctgaccgccgcgctcggcaccgacgaggac tccgtcgccgccgtgctgcccgccctgtcctcctggcgccgggcccgccgcgaccgctcc accgtggacgcctggcgctaccgcgtcgcctggaaacccctcggcggcaccctgccccac ccgtccatgaccggcacctggctgctggtcaccgccgacggcatcgacgacaccgatgtg gcaggggcgttggagacctacggcgccgaggtgcgccggctggtcctggacgaggagtgc gtcgaccgcgtcgtcctgcgggagcggctggccggcgtggaggatgtgaccggcatcgtc tccgtcctcgccgccgccgagcggaccgacgcggtaccgggcacctccctggtgctcggc accgccctgaccgtggcactgatccaggccctcggcgacgccgaaatcgacgctcccgta tgggcgttgacccgcggcgcggtctccaccggcagggccgacgagctgaccgcgcccgtc caggcgcaggtcaccggcatcggctggaccgcggcgctggagcacccgcagcgctggggc ggcaccctcgacctgcccgccgccctcgatgcccgggccgcccagcggctcgccgccgtg ctgtccggcgccctcggcggcgacgaccagctggccatccggccctccggggtcttcacc cgccgcatcgtgcgggccgaggccaccgccgggcggcccgccggcacctggacgccgcgc ggcaccacgctggtcaccggcggctccggcaccctcgccccgcacctcgcccgttggctg gccgaacgcggcgccgagcacctggtgctgatcagccggcgcggcacggccgccccgggc gccgccgaactcgtcgcggaactggccgagtcgggcaccgaggcgaccgtcgccgcctgc gacatcaccgaccgcgacgcggtcgccgcgctgctggccgacctcaaggccgacgggcgc accgtccgcaccgtcgtgcacaccgccgccaccatcgagctgcacaccctggacgccacc accctggcggacttcgaccgggtgctgcacgccaaggtcaccggcgcccaggtcctcgcc gaactgctcgacgacgaagagctggacgacttcgtcctgtactcctccaccgccggcatg tggggcagcggcgcccacgccgcctacgtcgccggcaacgcctacctcgccgcgctcgcc gagcaccgccgggcccgcggactgcccgccctgtcgctgtcctggggcatctgggccgac gacctcaagctgggccgggtcgatccccagatgatccggcgcagcggcctggagttcatg gacccgcagctggccctgagcggcctgcagcgggcgctggacgacaacgagaacgtgctc gcggtcgccgacgtggactgggagacctaccaccccgtctacacctccggccgccccacc ccgctcttcgacgaggtgccggaggtccgccggctcaccgcggccgccgagcagagcgcc gggaccgtcgccgagggcgagttcgccgccgcgctgcgcgccctgtccgacgccgagcag cagcgcaccctgctggagaccgtccgcaccgaggcggcgtccgtcctcgggctgtcctcc gccgaggacctcaccgaccagcgggccttccgcgacgtcggcttcgactcgctgaccgcc gtcggcctgcgcaaccggctcgcctccgtcaccggcctgacgctgccctcgacgatggtc ttcgactaccccaacccggccgcgctcgccgcctacctgcacggcgagctggccggcgcc cggaccgccgccggcgccgtcgccgtcccgaccagcgcgcccgccgccgacgacccgatc gcgatcgtcggcatgagctgccgctaccccggcggggtcggctccgccgaggacctgtgg cggatcgccctggacgaggtcgacgcgatctccggcttccccgccgaccgcggctgggac gccgagggcctctacgacccggaccccgaccggcccggccgcacctactccgtccagggc ggattcctgcgcaacgtcgccgagttcgacccgggcttcttcgggatctcgccgcgcgag gcgctgtcgatggacccgcagcagcggctcctgctggagaccgcctgggaggcgttcgag cacgccggcatcgacccggtcgcccagcgcggcagccgcaccggcaccttcgtcggcgcc agctaccaggactacgcctccagcgtgcccaacagcgagggctccgaaggccacatgatc accggcacgctctccagcgtgctgtccggccgggtgtcctacctcttcggcttcgagggc cccgccgtcacgctcgacaccgcctgctcctcgtccctggtcgccatgcacctggcctgc cagtccctgcgcaacggggagagctcgctggccctggccggcggcgtcagcatcatgtcc accccgatgtcgttcgtcggcttcagtcggcagcgcgccctcgccgaggacggccgctgc aaggcgtacgcggacggcgccgacgggatgaccctcgccgagggcgtcggcctggtgctg ctggagcggctgtccgacgcccgcgccaacgggcaccaggtgctcgccgtgatccgcggc tccgccgtcaaccaggacggcgcctccaacggcctgaccgcacccaacggcccgtcccag cagcgcgtcatccgccaggcactggccaactccgcggtggcgcccggcgacatcgacgtc ctggagggccacggcaccggaaccgccctcggcgaccccatcgaggcccaggccctgctc gccacctacggccaggaccgcgcccccgaacggccgctgctgctcggctcggtgaagtcc aacatcggccacacccagatggcgtccggcgtggccagcgtcatcaagctcgtccgcgcg ctccaggaaggcgtggtgcccaagtccctgcacatcgaccggcccaccacgcacgtcgac tggtcctcgggcgccatcgggctgctcaccgaacgcaccccgtggcccgagaccggccgg ccgcgccgcgccgccgtctcctccttcggcatcagcggcaccaacgtccacaccatcctc gaacaggcccccgcggacgaggcgcccgcgcccgccgacccgccgcgggacggcctggtg ccggtcctgctctccggccgcggcgaggccgcgctgcgcgcccaggccgcccgcctgctc gccttcgtcgaggagcggcccgaggcccacctcaccgacctcgcccactccctcgccacc tcgcgcgccgcgctggagcgccgcgccgccgtcatcgccgccgaccgcgacaccctgacc cgcggcctgcgcgccctgagctacggccggcccgaccccggcctggtccagggcaccgca ggacgcggccggaccgccttcctgttcaccggacagggcagccagcgcgccggcatgggc cgcgaactccacgaccgccacccggtgttcgccgacgcgctggacgaggtgctggcccgg ctcgacgacggaccggaccggccgctgcgcgaggtgctgttcgccgcgcccgactccgcc gaggccgcgctcctggaccggaccggctacgcccagcccgcgctgttcgccgtcgaggtc gcactgttccgcctgctggcgtcctggggcctggccccggactacctggccggccactcc gtcggcgagatcgccgccgcgcacgtcgccggcgtgctgtcgctggacgacgcctgcacc ctggtcgccgcccgcggccggctcatgcaggcgctgcccgagggcggcgcgatggtcgcc ctggaggccgcggaggacgaggtcctgccgctcctggaggggctcaccgaccgggtgtcc gtcgccgccgtcaacgggccgcggtccgtggtcgtcgccggcgtcgaggaggacgtgctc ctcctcgccgacctcttcgccgccgacgggcgccggaccaagcggctgcgggtgagccat gccttccactcgccgctgatggacgccatgctcgacgacttcgccgccgtcgcccgcggg ctgacctaccacccgccgacgatcccgttcgtgtcgaacgtcagcggcggcctggccacc gccgaacaggtctgcacgcccgactactgggtcgggcacgtccgcgcagcggtccgcttc gccgacggcatcgactggctcgccacccagggcgacgtccacaccttcctggagctcggc ccggacggcgtgctcagcggcatggcccgggagaacctcaccgacccgtcccgcacggcc ctgctgccgaccctgcgcggcgaccggcccgaggaaccggccctggtcaccgccgtcgcc gcggcccacgcgcacggcgcccgcgtcgactggagcgggtacttcgccgaccacggcgcg cgccggaccacgctgccgacctacgcgttccaacgcgagcggtactggcccgacaccacc gccgccgccgcgacggcccgcacgcccggatccgccctcgacgccgagttctgggccgcc gtcgagcgggacgacgtcgccgccctcgccgcctccctggacctggacgacgccaccgtc accgcgatggtccccgcgctcaccgcctggcgccggcgccgcggcgagcagagcgaactg gactcctggcgctaccgcgtcacctggaagccgcgcggcggcgccaccgcacccgccgcc ctcaccggccgctggctcgtgctggtcccgcacgaccaccaggaccggcaggacgccgag accgcggcctgggccgccgacgtcgagaccgccctgggcaccaccaccgtccggctgccg gtcaccaccaccgaccgcgccgcgctggccgcccggatcaccgaagtcgccggaacccag ggcccgttcagcggtgtgctgtccctgctgccgctcgccaccggcgacgccggccacccc ggtgcgcccgccgccctcaccctcaccaccaccgccgtccaggccctcggcgacgccggc atcgatgcgccgctgtggaacgtcacccgcggcgccgtggccgtcggccgcgccgagcag gtcaccgcgcccgaacaggccgccgtctggggcctgggccgcgccgtcgccctggaactg ccggcccggttcggcggcaccctcgacctgcccgccaccctggacggccaggccgcccgc cggctgcgcgcggtgctcgcggccaccgacggcgaggacgcggtggccctgcggccctcc ggcgtcttcctccgccgcctggcccacgccccggccggccccgacaccgcccgcaccgcc ttcgacccggcggccggcaccgtactgatcaccggcggcaccggcggcatcggcggccac gtcgcccgccgcctggcccgcgacggcgccacccacctgctgctcaccagccgccgcggc ccggccgcccccggcgccgacgcgctccgcgccgaactggaggaactgggcgcccgggtc accctcgccgcctgcgacgccgccgaccgcgacgcgctggccgcgctcctcgccgaactg cccgacgacgccccgctgtgcgcggtgttccacaccgccggcgtcgtcgaggaccacgtc gtggacgcgctcacaccggagagcttcgccgcggtgctgcgcgccaagaccgtcgccgcc caccacctgcacgagctgaccgccgacctggacctcgccgcgttcgtgctgttctcctcc acggccggcgtcctcggcgccgccggacagggcaactacgccgcggccaacgcccacctg gacgccctcgccgagcaccgccgctcccgcggcctgaccgcgctgtccgtcgcctggggc ccgtgggccggctccggcatggtcgccgacaccgccgaactcaccgaccgggtacggcgc ggcggcttcgaaccgctcgcccccgaaccggccgtgcgcgccctgctgcgcgccatcgag aacgacgacaccaccgtcgcgctcgccgacatcgactgggagcgcttccagcgcgccttc gccgcggtccgcccgctgccgttcgtcgccgacctccccgagaccggccgggccacggcc gcgactgccaccggcgccgccaccggcctgcggcagcgactcgccgaactgccggagcac gagcgcccggcagcggtcctggacctgctgcgcacccaggtcgccgccgtcctcggccac gccgacccgcgcaccgtcgaggacgaccacgccttccgcgacctgggcttcgactcgctg accatcctggaactgcgcaacgccctcaacgccgccaccggcctgagcctgcccgccacc ctggtctacgacctgcccaccccgcgcgagatggcggacttcctgctcgccgaactcctc ggcaccctgcccaccgacaccgccgcgatcgtcgccaccacgtcccccaagctctcagct tcgttcgagcagggcggtacccccttcgacgacgacccgatcgccgtcatcggcatcggc tgccgcttccccggcggcgtcaccaccccggaggagctctggcagctcctcgacgagggc cgcgacggcatcagccgcttccccgacgaccgcggctgggacctcgccgcgctgggcgcc ggcgcctccgacaccctggagggtggcttcctctccggcgtcgccgacttcgacgcccgg ttcttcggcatctcgccccgcgaggcgctggccatggacccccagcagcggctgctgctg gagaccacctgggaggcgctggagcgggccggcatcgacccggccgcgctgcgcggctcc accaccggcgtcttcgtcggcaccaacggccaggactacccgacgctgttgcgccgctcc gcctcggacgtggccggctacgtcgccaccggcaacaccgccagcgtgatgtccggccgg ctgtcctacgcgctcggcctcgaaggcccggccgtcaccatcgacaccgcctgctcctcc tcgctcgtcgccctgcactgggccggccgggcgctgcgcgccggcgagtgcgacctcgtg gtggccggcggcgtctcggtcatggccagcccggactccttcgtcgagttctccacccag ggcggcctggcgcccgacgggcgctgcaaggcgttctccgacgccgccgacggcaccgcc tggtccgaaggcgtcggcatcctcgtcctggaacgcctctccgccgcccgccgcaacggc caccaggtcctcggcctgatccgcggcaccgccgtcaaccaggacggcgcgtccaacggc ctgaccgcgcccaacggcctctcccagcagcgcgtcatcgcccaggcactcgccgacgcc cgcctgcgccccgccgacatcgacgcgatcgaggcgcacggcaccggcaccaccctcggc gacccgatcgaggcccgcgccctgatcaccgcctacggccgggaccgggacgccgaacgg ccgctgctgctgggcaccgtcaagtccaacatcggacacacccaggccgccgccggtgcc gccggcgtcatcaagatgctgatggcgatgcgccacggcaccctgcccaggacgctgcac gtgggcaccccgtccagtcacgtcgactggagcggcggcaccgtcgcgctcctcgacgac gcgcggccctggccacagaccgggcagccgcggcgcgccggcgtctccgccttcggcgtc agcggcaccaacgcccacgtcgtcgtcgagcaggcccccgaacccgaagcccccgccgcc gacgccccggccgccgagccggcaccggaggccacgcccaccgtcgtcccctggatcgtc tccggacgcagccgggaagcgctccaggcgcaactggaccgtctcaccgcgcacaccgcc gcccaccccgcgcgctcggcggcggacgtcggccgctcgctggccaccgaccgcacgctc ttcccgcaccgcgccgtgctgctcgccggcccggacggggtgcgcgaggccgcccgcgcc accgcgccccgcacccccggccgcaccgcgttcctgttctccgggcagggcgcccagcac gccctgatgggccacgacctgtaccagcgcttcccggtctacgccgacgcactggacacc gtcctcgcccagttcgacaccgtgctggacgtcccgctgcgcgccgcgctgttcgccgcg cccggcacccccgaggccgcgctcctggaccagaccggcttcacccagcccgcgctgttc gccgtcgaggtcgcgctgttccggctcgccgagtcctggcggctgacgccggacttcgtc gccggccactccatcggcgagatcgccgccgcacacgtcgccggggtgttctccctggag gacgcctgcacactggtcgccgcccgcgcctccctcatgcagcaactgccgcaggacggc gcgatggtggccctggaggccaccgaggacgaggtcgcgccgctgctcaccgacggcgtc gcggtcgccgcggtcaacggcccccgctcggtggtcgtcgccggcgccgaggacgccgtc cgcgcggtcgccgaccggctcgccgccgacggccgccgcacccgccggctgacggtcagc cacgccttccactcgccgctgatggacccgatgctcaccgagttcgcccgggccgcggag ggcctgacctaccacgagccgcgcatccccctcgtctccaccctcctcggcgccccggcc ggcgccgaactgcgcacccccggctactgggtgcggcacgtccgcgagaccgtgcggttc gccgacggcgtgcgcgccctgcacgacgccggcgccggcaccttcgtggagatcggcccg gacggcgtgctcgccgccctgacccagcagaccctcgacaccgtcgaggccggcgcgccc gccgtcgtcgtgccgctccagcgccgcgaccgcgccggcgaccttgccctcctggagggc ctggccaccctgcacacccacggcaccggcccgtcctggcccgcctacttcgaggccacc ggcggccaccggaccgatctgcccacctacgccttccagcgggagcggtactggcccgag cccggcgcccccgcggacgccccgcaggacccggccgacgccgccttctggacggccgtc gaacgcgcggacctggagggcctggccgcctccctcggcctggacggcgacaccgtcacc gcgatggtgccggcgctgtccgcctggcggcgccgccagggcgcccggtccgccgccgcg cagtggcgctaccacgagacctgggccccgctgccggcacccgagacgaccgcaccggcc ggccgcgccctggtcctcgtcccggccgggaaccgcgacaccgcctggatgacggccgtc gccgacgcactcggcgacaccgtcacgaccgaacccgacgccctggccgagcagttgacg gccgccggcgacacaccctggcgcgtcgtggtgtcgctgctcgccgccgcgtccgaggag ctgcccgcggacggggcctggcccgccgccctcctcgccaccctggacgaggccggcgtg cacgcgcccctgtggtgcgtcacccgcggcgccgtcgcggtcgcgggggagcccccgacc gccgtcggccaggccgccctgtggggcctgggccgggtcgccgcgctggaccacccggac cgcttcggcggcctggccgacctgcccgccgacaccgacgcgcacgccgccgggctgctc gccgcacacctggccgcgccgggcaccgaggccgagatcgcggtccgcgccaccggcatc cacgcccgtcgcctggtccgtatgccggccgccgccgacggcgccacctggctgccgacc ggcaccgtcgtggtcgtcggcggcaccggcaccatgggcggtcgggccgcccgctggctg gcccgcgagggcgcccgccacctcgtcctgaccgcccccggcgacaacacgacctccgac gacaacacgaccaccgaggccctgacggccgaactggccgcgttcggcgcccggatcacc gtcgtggaccacgaccccaccgctccggacggcttcgccgcgctcctcgacggactgccc gacgacaccccgctcaccgcggtcgtgtacgcgccggaggccgacgccacccccgacacc gcggccgagctgtccgccgcgctcgcccccgtcaccgccctcggcgccgccctcaccggc cggccgctggacgccttcgtcctcttcggctccatcgccggcgtctggggcgtgcgcggc cgggccgccgaggccgcgtccggcgcctacctcgacgccttcgcccgcgcctgccgcgac cgcggcaccccggcgctggccgtcgcctggggcgcctggtccggcctggccgaccggtcc ctcgccgcccacctgcggatgaacggcctgccggtgatggacgcggacaccgcactggcc gccctcggccgggccgtcgccgacgggtccgccgccgagacggtcgccgacgtccgctgg gagaccttcgcgcccctccaccacgaggcccgccgcaccgccctgttcgacgccctgccc gaggcccgcggcgcgctcgccgaggccgcccgggaccgcgccgaccgacagaccgccgcc ggcgactacggccggtggctcgccgagcagcccgccgcggaccacgacgccgtcctgctg gcactggtcaccgagaaggccgcgaccgtcctcggccacgccgaccacgacctgctcgaa cccgatctgcccttccgcgacctgggcttcgactcgctgaccgcggtcgacctgcgcaac cagctcaccgcggaaaccggcctcgccctgcccgccaccctcgtcttcgaccaccccaac ccggccgccctcgccgcccacctgcgcgcccaactcctgggcgaggcggtcgactccgcc gcaccggtggccgcccccgtcgcctccggcgccgacgacgacgcgatcgtcatcgtcggc atggcctgccgctaccccggcggggtcacctcgcccgaggacctgtggcagctggtcggc gacgagatcgatgcggtcggcgacttcccgaccgaccgcggctgggacctggccgcgctc gccggcgacggaccgggccgcagcgccaccgcccagggcggattcctctacgacgccacc gacttcgaccccggcctgttcggcatctcgccgcgcgaggccctggtgatggacccgcag cagcggatcctgctcgaaacgtcctgggaggccctggagcgggccggcatcgacccggcg acgctgcgcggcagcggcaccaccggcgtcttcgtcggcggcggctccggcgactaccgg ccgccggaggaggccgggcagtggcagaccgcccagtccgccagcctgctctccggtcgc ctcgcctacaccttcggcatccagggccccaccgtgtcggtcgacaccgcctgctcctcg tcgctggtcgcgctgcacctggccgcgcaggccctgcgcgccggcgaatgctcgatcgcg ctggccggcggcgtgaccgtgatggccaccccggtgggcttcgtcgagttcagcgcccag ggcgccctgtcgccggacggccgctgccgggccttctccgacgacgccaacggcaccggc tggtccgaaggcgtgggcatgctcgtcgtcgaacggctctccgacgcccgccgcaacggt caccgcgtcctcgccgtgctccgcggctccgccatcaaccaggacggcgcgtccaacggc ctgaccgcccccagcggccccgcccagcagcgcgtcatccgccaggccctcgccaacgcc cgcctgcgccccgccgacatcgacgccgtcgaggcgcacggcaccggcaccaagctcggc gaccccatcgaggcccaggccctgctcgccacctacggccaggaccgcgaacggcccgtg ctgctcggctcgctgaagtccaacatcggccacacccaggccgcctccggcgtcggcggc gtcatcaagatggtcctcgccatgcagcacggcgaactgccgcgctccctgtacgccgag aacccctcgtcgcacgtggactgggccgccggccgcgcccacctgctcaccgccaggacc ccgtggcccgactccggtcggccgcgccgcgccgccgtctcctccttcggtgccagcggc accaacgcccacgccatcctggagcagccgccgcgcgaggaactgcccgcgcgccccgcg gacgacggcgccccgctgccgttcctgctctccggccgctcgcagaacgccctgcgcgcc caggcccgccgactcctggcccgcctcaccgcccgccccgacacccggaccgccgacctg gcgtactccctggcgaccacccgggccgccttcgagcaccgggccgcgatcaccgccacc gaccacgacggcctccgcaccggcctgaccgccgtcgccgagggcaccaccgccccgcac accgccgaacaccacctccagcgcaccggaaagcgcgccgtgctcttctccggccagggc tcccagcgcctgggcatgggccgcgaactgtacgagcgccacccggtgttcgccgaggcg ttcgacgccgtactggcccgcctcgacgaccggctcgacacccccctgcgggacgtcgtc tggggcaccgacgaggaggcgctgcacgccaccgggaacacccagcccgccctgttcgcc gtcgaagtcgcgctctaccgcctgatcgaatcctggggcgtgcggcccgacttcgtggcc ggtcactccgtcggcgagctcgccgcggcccacgtcgccggggtgctctccctggacgac gcctgccgcctggtcgccgcccgcgccgccctgatgcagcgcctcccggccggcggcgcc atgatcgccgtcgaagccaccgaggacgaggtcaccccgctcctcaccgacggcgtgtcc ctcgccgcggtcaacggcccgaccgccgtggtcctctccggcgcgggcgacgccgtgacc gccctggccgagacgctggccgaacggggccaccgcaccacccggctgcgggtcagccac gccttccactcgcacctcatggacccgatgctggcggacttccgtaccgtcgccgagggc ctggaataccacccgccgcgcatccccgtggtctccaacctcaccggggacgtcgccgac gcggccgacctgtgctccgccgactactgggtgcgccacgtccgcggcaccgtacggttc gccgacggcgtgcgcaccatggccgaccgcggcgtgcacctcttcctcgaactcggcccg gacgccgtgctgtcggccatggcccgccagtgcgcaccggacgccgtcgtcgtcccggcc ctgcgccgcacccgcggcgaggacgagacgctggtcggcgccgtcgcgcacctgcacgtc cacggcgcgggtccgcgctgggacgcgtacttcgccggccgcggcgcccagtggctggac cttccgacgtaccccttccagcgcggccgcttctggccggagtcccttccgggcgccgca tcggtcgccccggcagccggacagccggccgagaccgacgcggccttctgggacgccgtc gcacaggaggacttcaccgcattggaatccgtactcgacgtcgagagcgacgcactgtcc aaggtgctgccggccctgatggactggcgcagccgccaggccgacgagtcccaactggtg agctggcgccaccgcatcgtctggaagcggctcaccggcgccgccctggcacaccgcaag gcgctcagcggcacctggctcgcggtggtccccgagggcctcgccgacgacccctgggtg accaccaccctcgacggcctcggcacccacctcgtgcgtctggaggtcgcggaggccgac cgggccgcgctggccgacgcgatcgcggcccgcaccgccgacggcacccgcttcggcggc gtggtctccctgctggccctgcgcgacacgctcaccggcgcggtgcccgagggcaccgcc ctgaccaccgtcctcctccaggccctcggcgacgccggcgtcgacgcaccgctgtggtgc gtcacccgcagcgccgtctccgccggccgcaccgaccggccgcaccgaccgctccaaggc gccgtctggggcctgggccgggtcgcggccctggagcacccgcagcgctggggcggcctg gtggacctgccggaggagcccgacgagcggtccgcggccggcctcgccgccgtcctggcc ggtctggacggcgaggaccaggtcgccgtgcgcggcaccgcggtgctcgcccgccgactg gtgccggcccccggccgcaagtcgtcccggccctggcacccgtccggcaccgtcctggtc accggcggcaccggcgccctcggcgcgcacgtcgcccgccgcctggccaaggacggcgcc cagcacctcgtcctgctcagccgccgcggcccggacgcccccggtgcggcggaactgcgc gcggaactcgacgcgttgggcaccggcgtcaccgtcgccgcctgcgacgtcgccgaccgc gaccagctgacggccgccctggacgcgctgcccgccgaccggccgctgaccggcgtggtg cacaccgccggcgtcctcgacgacggcgtgctggaccggctcacccccgagcggttccag gaggtgttccgcgccaaggtcacctcggccctgctgctggacgagctgacccgggaccgc gagctggccgcgttcgtcctcttctcctccgcctccgccgcggtcggcaacccgggccag gccaactacgccgccgccaacgccgtcctggacgcgctcgccgaacagcgccgggtgctc ggcctgcccgccacctcggtctcgtggggtgcctggggaggcggcggcatggccgacgcc gacggcgccgacgaggccgcccggcgcgccggggtcggcgccatggacccgcacctcgcc gtggaggccctgctgcgcctggtcgccgagaaggagccgaccgcggtggtcgccgaggtg gccctggaccggttcgccggcgccttcggcggcagccgacccagcgccctgctgcgggag ttccccggctaccgcgaggcgctcgccgcccaggcggagcaggccgcggacggcggcggg ctcgccgcccgactggccgcgctgccgcccgcccgccgcctggacaccgtcgtggacctg gtgcgcacccgcgccgcgcaggtgctcggctaccccgacaccgaagcggtcgccgccgaa cggtccttccgcgacctgggtgtcgactccctcggtgccgtcgagctgcgcaaccaactg agcgcggccaccggcctgaacctgccggcgacgctggtcttcgaccacccgacccccctg gccctgggggagcacatcctcggcgggctcttcccggacgagccggccgggtccgacgac gagacggagatccgggccctgctggcctccgtcccgctcgaccaactgcgggagatcggg gtcctggagcccctgctccagctcgccggacgcggcggccgggccgcggacgacgacgac ggcgagtccgtcgactcgatgacagtggcagacctggtgcgggccgcgctcaacggccag tccgacctgtag

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