KEGG ORTHOLOGY: K16687

ORTHOLOGY: K16687

Entry

K16687                      KO

Symbol

YAP1, Yki

Name

transcriptional coactivator YAP1

Pathway

map04390

Hippo signaling pathway

map04391

Hippo signaling pathway - fly

map04392

Hippo signaling pathway - multiple species

Disease

H01114

Ocular coloboma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K16687  YAP1, Yki; transcriptional coactivator YAP1
   04391 Hippo signaling pathway - fly
    K16687  YAP1, Yki; transcriptional coactivator YAP1
   04392 Hippo signaling pathway - multiple species
    K16687  YAP1, Yki; transcriptional coactivator YAP1

Genes

HSA:	10413(YAP1)

PTR:	451506(YAP1)

PPS:	100988662(YAP1)

GGO:	101126226(YAP1)

PON:	100456879(YAP1)

PPYG:

129007344(YAP1)

NLE:	100607618(YAP1)

HMH:	116476857(YAP1)

SSYN:

129479555(YAP1)

MCC:	704382(YAP1)

MCF:	102134227(YAP1)

MTHB:

126936003

MNI:	105493722(YAP1)

CSAB:

103248330(YAP1)

CATY:

105591399(YAP1)

PANU:

101025805(YAP1)

TGE:	112606341(YAP1)

MLEU:

105534421 105542730(YAP1) 105549807

RRO:	104674655(YAP1)

RBB:	108514081(YAP1) 108525471

TFN:	117074134 117079975(YAP1)

PTEH:

111540064(YAP1)

CANG:

105500931(YAP1)

CJC:	100393920(YAP1)

SBQ:	101028891(YAP1)

CIMI:

108307640(YAP1)

ANAN:

105719109(YAP1)

CSYR:

103261078(YAP1)

MMUR:

105874572(YAP1)

LCAT:

123641909(YAP1)

PCOQ:

105822268(YAP1)

OGA:	100948954(YAP1) 100950695

MMU:	22601(Yap1)

MCAL:

110301372(Yap1)

MPAH:

110327706(Yap1)

RNO:	363014(Yap1)

MCOC:

116073817(Yap1)

ANU:	117699732(Yap1)

ASYL:

127689443(Yap1)

MUN:	110553753(Yap1)

CGE:	100761993(Yap1)

MAUA:

101835954(Yap1) 121138384

PROB:

127232847(Yap1)

PLEU:

114707997(Yap1)

MORG:

121451552(Yap1)

MFOT:

126513677

AAMP:

119808932(Yap1)

NGI:	103746488(Yap1)

HGL:	101699461(Yap1)

CPOC:

100726570(Yap1)

CCAN:

109689099(Yap1)

DORD:

105980855(Yap1)

DSP:	122110392(Yap1)

PLOP:

125349686(Yap1)

NCAR:

124958578

MMMA:

107145912(Yap1)

ITI:	101959251(Yap1)

OCU:

100341323

OPI:	101525508(YAP1)

TUP:	102500981(YAP1)

GVR:	103586683(YAP1)

CFA:	479465(YAP1)

CLUD:

112671449(YAP1)

VVP:	112925903(YAP1)

VLG:	121499555(YAP1)

NPO:	129496624(YAP1) 129514518 129514781

AML:	100479925(YAP1)

UMR:	103662547(YAP1)

UAH:	113259721(YAP1)

UAR:	123792450(YAP1)

ELK:

111153716

LLV:

125110228

MPUF:

101692754(YAP1)

MNP:	132021940(YAP1)

MLK:	131834504(YAP1)

NVS:	122912260(YAP1)

ORO:	101373425(YAP1)

EJU:	114211396(YAP1)

ZCA:	113913865(YAP1)

MLX:	118013142(YAP1)

NSU:	110586383(YAP1)

LWW:	102746331(YAP1)

FCA:	101101408(YAP1)

PYU:	121020755(YAP1)

PCOO:

112865901(YAP1)

PBG:	122482883(YAP1)

PVIV:

125175968(YAP1)

LRUF:

124505821

LGF:	123602230(YAP1)

AJU:

106976481

PTG:	102952013(YAP1)

PPAD:

109257508(YAP1)

PUC:

125929815

PLEZ:

122199440(YAP1)

HHV:	120219679(YAP1)

BTA:	100336629(YAP1)

BOM:	102270556(YAP1)

BIU:	109568766(YAP1)

BBUB:

102392672(YAP1)

BBIS:

104980153(YAP1)

CHX:	102174763(YAP1)

OAS:	100913160(YAP1)

BTAX:

128060123(YAP1)

CSUM:

138093182(YAP1)

ODA:	120876086(YAP1)

CCAD:

122450361(YAP1)

MREE:

136175289(YAP1)

OVR:	110128545(YAP1)

MBEZ:

129554251(YAP1)

SSC:	100622418(YAP1)

CFR:	102513506(YAP1)

CBAI:

105083473(YAP1)

CDK:	105087179(YAP1)

VPC:	102530459(YAP1)

BACU:

103006631(YAP1)

BMUS:

118898951(YAP1)

LVE:	103087231 103090880(YAP1)

OOR:	101275649(YAP1)

LALB:

132526254(YAP1)

DLE:	111168364(YAP1)

PCAD:

102981362(YAP1)

PSIU:

116757898(YAP1)

NASI:

112409969(YAP1)

ECB:	100068834(YAP1)

EPZ:	103552623(YAP1)

EAI:	106845874(YAP1)

MYB:	102245730(YAP1)

MYD:	102772732(YAP1)

MMYO:

118664473(YAP1)

MLF:	102430639(YAP1)

MDT:	132235342 132240630(YAP1)

MYUM:

139017457(YAP1)

PKL:	118712462(YAP1)

EFUS:

103292959(YAP1)

MNA:	107532419(YAP1)

DRO:	112317550(YAP1)

SHON:

118975701(YAP1)

AJM:	119054052(YAP1)

PDIC:

114498571(YAP1)

PHAS:

123805414(YAP1)

MMF:	118628799(YAP1)

PPAM:

129085984(YAP1)

HAI:	109375123(YAP1)

RFQ:	117030193(YAP1)

PALE:

102893390(YAP1)

PGIG:

120618087(YAP1)

PVP:	105298276(YAP1)

RAY:	107504642(YAP1)

MJV:	108409418(YAP1)

TOD:	119240921(YAP1)

SARA:

101546704(YAP1)

SFUM:

130024315(YAP1)

SETR:

126016080(YAP1)

LAV:	100655000(YAP1)

TMU:

101343035

ETF:	101659756(YAP1)

DNM:	101424840(YAP1)

MDO:	100010658(YAP1)

GAS:	123240788(YAP1)

SHR:	100932865(YAP1)

AFZ:

127554919

PCW:	110214963(YAP1)

TVP:	118837842(YAP1)

PBRV:

138154992(YAP1)

OAA:	100079225(YAP1)

TACU:

119941341(YAP1)

GGA:	396171(YAP1)

PCOC:

116230611(YAP1)

MGP:	100544949(YAP1) 104917587

CJO:	107308391(YAP1)

TPAI:

128074804(YAP1)

LMUT:

125692853(YAP1)

NMEL:

110389915(YAP1)

APLA:

101798117(YAP1)

ACYG:

106034160(YAP1)

CATA:

118245865(YAP1)

AFUL:

116492663(YAP1)

TGU:	100219556(YAP1)

LSR:	110470014(YAP1)

SCAN:

103812520(YAP1)

PMOA:

120506623(YAP1)

OTC:	121342528(YAP1)

PRUF:

121364190(YAP1)

ATRC:

139593350(YAP1)

GFR:	102031987(YAP1)

FAB:	101820782(YAP1)

OMA:	130248477(YAP1)

PHI:	102110056(YAP1)

PMAJ:

107209500(YAP1)

CCAE:

111924360(YAP1)

CCW:	104690067(YAP1)

CBRC:

103617955(YAP1)

ACOE:

138110138(YAP1)

ETL:	114067048(YAP1) 114070500

ZAB:	102070819(YAP1)

ZLE:	135450411(YAP1)

ACHL:

103810515(YAP1)

SVG:	106859375(YAP1)

MMEA:

130576280(YAP1)

HRT:	120748487(YAP1)

SATI:

136357578(YAP1)

CCIC:

134057530(YAP1)

FPG:	101913470(YAP1)

FCH:	102053144(YAP1)

SHAB:

115604081(YAP1)

ACUN:

113483903(YAP1)

TALA:

104362847(YAP1)

ACHC:

115353432(YAP1)

HALD:

104314293(YAP1)

HLE:	104838456(YAP1)

AGEN:

126048368

HHAR:

128153333(YAP1)

GCL:

127012792

CSTI:

104554636(YAP1)

LDI:	104348745(YAP1)

DPUB:

104298361(YAP1)

PPUS:

135189812(YAP1)

BRHI:

104496843(YAP1)

EGZ:	104128907(YAP1)

NNI:	104023074(YAP1)

PCRI:

104027577(YAP1)

PCAO:

104051604(YAP1)

PADL:

103918924(YAP1)

AFOR:

103905922(YAP1)

FGA:	104084104(YAP1)

GSTE:

104260472(YAP1)

CBOY:

140646548(YAP1)

CLV:	102090528(YAP1)

MUI:

104540457

PGUU:

104468304(YAP1)

PLET:

104616432(YAP1)

EHS:	104509171(YAP1)

CUCA:

104054971(YAP1)

TEO:	104379639(YAP1)

BREG:

104639310(YAP1)

OHA:	104333029(YAP1)

CPEA:

104390309(YAP1)

CVF:	104290316(YAP1)

RTD:	128904207(YAP1)

CRID:

134513348(YAP1)

AAM:	106495532(YAP1)

AROW:

112971960(YAP1)

NPD:	112943709(YAP1)

TGT:	104574105(YAP1)

DNE:	112988750(YAP1)

SCAM:

104143705 104151767

ASN:	102368979(YAP1)

AMJ:	102564149(YAP1)

CPOO:

109305544(YAP1)

GGN:	109302573(YAP1)

PSS:	102449321(YAP1)

CMY:	102941480(YAP1)

CCAY:

125633828(YAP1)

DCC:	119845627(YAP1)

CPIC:

101946225(YAP1)

TST:	117871180(YAP1)

CABI:

116814904(YAP1)

MRV:	120368854(YAP1)

ACS:	100554222(yap1)

ASAO:

132772204(YAP1)

PVT:	110080245(YAP1)

SUND:

121925438(YAP1)

PBI:	103052613(YAP1)

PMUR:

107286354(YAP1)

CTIG:

120297724(YAP1)

TSR:	106543296 106555416

PGUT:

117660782(YAP1)

APRI:

131199265(YAP1)

PTEX:

113440468(YAP1)

NSS:	113417322(YAP1)

VKO:	123029052(YAP1)

PMUA:

114595658(YAP1)

PRAF:

128412581(YAP1)

ZVI:	118084708(YAP1)

HCG:	128351173(YAP1)

GJA:	107121572(YAP1)

STOW:

125431115(YAP1)

EMC:	129325505(YAP1)

XLA:	100381098(yap1.S) 100653494(yap1.L)

XTR:	100488779(yap1)

NPR:	108786932(YAP1)

RTEM:

120929023(YAP1)

BBUF:

120996406(YAP1)

BGAR:

122930570(YAP1)

PWL:	138248639(YAP1)

MUO:	115468487(YAP1)

GSH:	117362613(YAP1)

DRE:	561411(yap1)

SRX:	107746561 107758259

SANH:

107662128 107687356

SGH:	107554467(yap1) 107560159

CCAR:

109073035 109110178

CAUA:

113061663 113118470

CGIB:

127934311 127977589

PTET:

122362941(yap1)

LROH:

127180765(yap1)

OMC:	131524136(yap1)

PPRM:

120487722(yap1)

RKG:	130089113(yap1)

MAMB:

125254677(yap1)

CIDE:

127499468

CERY:

137023439(yap1)

MASI:

127416819 127456076

TROS:

130562660(yap1)

TDW:	130435617(yap1)

MANU:

129418868(yap1)

PDAB:

135769700 135773467

IPU:

108264673

IFU:	128606531(yap1)

PHYP:

113526742(yap1)

SMEO:

124396061(yap1)

TFD:	113638060(yap1)

TVC:	132850983(yap1)

CGAR:

128527977(yap1)

NGRA:

132887780(yap1)

TRN:	134323583(yap1)

AMEX:

103032802(yap1)

CMAO:

118817882(yap1)

EEE:	113579063(yap1)

CHAR:

122130504(yap1)

SPIL:

134100010(yap1)

TRU:	101067712 101070596(yap1)

TFS:	130535095(yap1) 130537183

TNG:	GSTEN00018977G001 GSTEN00035240G001

LCO:	104925961(yap1) 104934526

NCC:	104962615(yap1) 104964662

TBEN:

117468812(yap1) 117490367

CGOB:

115018204(yap1) 115019058

PGEO:

117457349(yap1) 117459015

GACU:

117536160 117562022(yap1)

EMAC:

134872070 134880242(yap1)

ELY:	117259966(yap1) 117267389

EFO:	125888744(yap1) 125898107

PLEP:

121943188 121952340

SLUC:

116048415(yap1) 116064884

ECRA:

117941639(yap1) 117955172

ESP:	116682904(yap1) 116700031

PFLV:

114553181(yap1) 114567108

GAT:	120821378 120825616

PPUG:

119214559(yap1) 119215055

AFB:	129089486(yap1) 129113852

CLUM:

117741918(yap1) 117743004

PSWI:

130191824 130210891(yap1)

CANA:

137790931(yap1) 137802096

CVE:	137875169(yap1) 137876361

MSAM:

119882795(yap1) 119895115

SCHU:

122878894(yap1) 122888221

CUD:	121518462 121520957(yap1)

SPUL:

138597195(yap1) 138605151

LMIX:

132980746(yap1) 132987895

ALAT:

119009494(yap1) 119030724

ASTR:

137596864(yap1) 137606443

MZE:	101485529 101486348(yap1)

ONL:	100705595 100710066(yap1)

OAU:	116313605 116329249(yap1)

OLA:	101168066 101170776(yap1)

OML:	112142768 112149815(yap1)

CSAI:

133442442(yap1) 133459636

XMA:	102217999(yap1) 102236505

XCO:	114153416 114161920(yap1)

XHE:	116707745(yap1) 116728288

PRET:

103475031(yap1) 103475479

PFOR:

103131119 103140998 103150360(yap1)

PLAI:

106955043 106957728(yap1)

PMEI:

106919004 106921226

GAF:	122833125(yap1) 122844406

PPRL:

129359163(yap1) 129368464

CVG:	107093476(yap1) 107098509

CTUL:

119775859 119782066(yap1)

GMU:	124876822 124884216(yap1)

NFU:	107380183(yap1) 107386361

KMR:	108236034(yap1) 108237007

ALIM:

106514083 106520596(yap1)

NWH:	119410733(yap1) 119420585

AOCE:

111575397(yap1) 111580660

EJA:	138196402 138205404(yap1)

BFRE:

138631392(yap1) 138634685

MCEP:

125013356(yap1) 125021433

CSEM:

103377837(yap1) 103395116

POV:	109628751 109630305(yap1)

SSEN:

122760503 122773975

SSOE:

131458771 131462558(yap1)

HHIP:

117773364(yap1) 117774166

HSP:	118105837(yap1) 118122603

PPLT:

128456883

SMAU:

118299878(yap1) 118300192

LCF:	108876204 108893390

SDU:	111233641(yap1) 111234613

SLAL:

111654063(yap1) 111666236

XGL:	120791525(yap1) 120802621

HCQ:	109509726 109526208(yap1)

SSCV:

125972866(yap1) 125982360

SBIA:

133491596 133504426(yap1)

PEE:	133405024(yap1) 133415983

PTAO:

133467412 133482525(yap1)

BPEC:

110158472 110163546(yap1)

ENY:	140360769 140366896(yap1)

MALB:

109959275 109968460(yap1)

BSPL:

114868601(yap1) 114869565

SJO:	128360472(yap1) 128371881

SSCO:

133980682(yap1) 133994574

GMH:	115546553 115561260(yap1)

SASA:

106595041 106613407

STRU:

115153796 115163860 115206739

OTW:	112235683 112240289(yap1) 112241743

OMY:	110503298 110518838(yap1) 110533247

OGO:	123992449(yap1) 124015724

ONE:

115116008

OKI:	109873487 109876587 109886300

OKE:	118378524 118382746 118390625

OMM:	135546748 135551090 135553258

OCLA:

139382945 139385684 139385701 139417897

SALP:

111973573

SNH:	120018909 120056723

CCLU:

121559720 121566823

ELS:	105006428 105006667(yap1)

OEP:	134028681(yap1) 134039972

SFM:	108941885(yap1)

PKI:	111838004 111841422

AANG:

118210274 118235599

AROT:

135236579 135263757

CCOG:

133107982 133133658

LOC:	102687817(yap1)

PSPA:

121302551(yap1)

ARUT:

117405624 117962710 117972710

PSEX:

120523236(yap1)

LCM:	102352258(YAP1)

CMK:	103177586(yap1) 103184440(wwtr1)

RTP:	109936542(wwtr1) 109939035(yap1)

CPLA:

122550415(yap1) 122555664

HOC:	132816335(yap1) 132821776(wwtr1)

LERI:

129698293(yap1)

PMRN:

116944606 116954415 116956333

LRJ:	133340669 133357275 133357619

BFO:

BBEL:

CIN:

SCLV:

SPU:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG4005(yki)

DER:

6548114

DSE:

6613013

DSI:	Dsimw501_GD24973(Dsim_GD24973)

DYA:	Dyak_GE11487

DAN:

DSR:

DPO:

DPE:

DMN:	108160392 117188085

DWI:

6640548

DGR:

6559099

DMO:	Dmoj_GI18856

DAZ:

108616082

DNV:

108652967

DHE:

111600052

DVI:	6625794(yki)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119681795 119682373

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135960605(yki)

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ000289 CpipJ_CPIJ000291

CPII:

CBRI:

CNS:

BCOO:

LLL:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:	114871570 114871578

OLG:

MGEN:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139110962(Yki)

TLN:	139816696(Yki)

HST:

DQU:

CFO:

FEX:

PMEC:

138944663(Yki)

LHU:	105675777(yki)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124211773(yki)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138140330(yki)

DPA:

109537927

ESIM:

136409690(yki)

EFOR:

136348572(yki)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:	111515469 111516517

DVV:	114332535 126880078

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_215621

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137926859(yki)

PRAP:

110994345

PBX:

123716750

PNAP:

125052707

ZCE:	119829344 119829564

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM613740

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138703458(yki)

BROR:

134535154

IEL:

124153921

HAMR:

139688003(yki)

FCD:

110845152

DPX:	DAPPUDRAFT_328360

DMK:

DPZ:

AFRA:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123765510(yki)

CQD:

128686156

PTRU:

123516259

MNZ:

135209685

MRJ:	136855400(yki)

PORN:

139755341(yki)

HAZT:

108677142

EAF:

111717509

LSM:	121119633(yki)

TCF:

PPOI:

ISC:

DSV:

RSAN:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136989064(yki)

PTEP:

107437904 107442288

ABRU:

129965842 129966768

UDV:	129224408 129233468

SDM:	118190952 118202205

LPOL:

106457267 106464392 106475602 111087139

PMEO:

129585977

CEL:	CELE_F13E6.4(yap-1)

CBR:

CBG_04520

CRQ:	GCK72_023622

BMY:	BM_BM8181(Bma-yap-1)

LOA:	LOAG_03508

TSP:	Tsp_08491 Tsp_08492

LGI:	LOTGIDRAFT_237382

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OSN:

LJP:

LAK:

SMM:	Smp_014840

LLON:

135494981

NVE:

5506788

EPA:	110241126 110242078

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130635504 130635617

RES:

135684743

TAD:	TRIADDRAFT_52157

» show all

Reference

PMID:12807903

Authors

Komuro A, Nagai M, Navin NE, Sudol M

Title

WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus.

Journal

J Biol Chem 278:33334-41 (2003)
DOI:10.1074/jbc.M305597200

Sequence

[hsa:10413]

LinkDB

DBGET integrated database retrieval system