KEGG ORTHOLOGY: K17562

ORTHOLOGY: K17562

Entry

K17562                      KO

Symbol

PPP1R21, CCDC128, KLRAQ1

Name

protein phosphatase 1 regulatory subunit 21

Disease

H02397

Neurodevelopmental disorder with movement abnormalities or hypotonia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17562  PPP1R21, CCDC128, KLRAQ1; protein phosphatase 1 regulatory subunit 21
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K17562  PPP1R21, CCDC128, KLRAQ1; protein phosphatase 1 regulatory subunit 21
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K17562  PPP1R21, CCDC128, KLRAQ1; protein phosphatase 1 regulatory subunit 21
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Rab GTPases and associated proteins
   FERRY complex
    K17562  PPP1R21, CCDC128, KLRAQ1; protein phosphatase 1 regulatory subunit 21

Genes

HSA:	129285(PPP1R21)

PTR:	740025(PPP1R21)

PPS:	100987706(PPP1R21)

GGO:	101150762(PPP1R21)

PON:	100457534(PPP1R21)

PPYG:

129029955(PPP1R21)

NLE:	100594579(PPP1R21)

HMH:	116482895(PPP1R21)

SSYN:

129461685(PPP1R21)

MCC:	715917(PPP1R21)

MCF:	102138644(PPP1R21)

MTHB:

126934242

MNI:	105464999(PPP1R21)

CSAB:

103220312(PPP1R21)

CATY:

105590618(PPP1R21)

PANU:

101008795(PPP1R21)

TGE:	112605196(PPP1R21)

MLEU:

105540843(PPP1R21)

RRO:	104668949(PPP1R21)

RBB:	108527521(PPP1R21)

TFN:	117062331(PPP1R21)

PTEH:

111550416(PPP1R21)

CANG:

105507508(PPP1R21)

CJC:	100412064(PPP1R21)

SBQ:	101042435(PPP1R21) 101047417

CIMI:

108317810(PPP1R21)

ANAN:

105726155(PPP1R21)

CSYR:

103271228(PPP1R21)

MMUR:

105866216(PPP1R21)

LCAT:

123636905(PPP1R21)

PCOQ:

105805886(PPP1R21)

OGA:	100949653(PPP1R21)

MMU:	73825(Ppp1r21)

MCAL:

110312428(Ppp1r21)

MPAH:

110335424(Ppp1r21)

RNO:	362697(Ppp1r21)

MCOC:

116079649(Ppp1r21)

ANU:	117716908(Ppp1r21)

ASYL:

127687698(Ppp1r21)

MUN:	110552894(Ppp1r21)

CGE:	100771957(Ppp1r21)

MAUA:

101833688(Ppp1r21)

PROB:

127214939(Ppp1r21)

PLEU:

114709287(Ppp1r21)

MORG:

121432903(Ppp1r21)

MFOT:

126504061

AAMP:

119807954(Ppp1r21)

NGI:	103725735(Ppp1r21)

HGL:	101710638(Ppp1r21)

CPOC:

100730556(Ppp1r21)

CCAN:

109694774(Ppp1r21)

DORD:

105986884(Ppp1r21)

DSP:	122104516(Ppp1r21)

PLOP:

125356459(Ppp1r21)

NCAR:

124963649

MMMA:

107137296(Ppp1r21)

ITI:	101969010(Ppp1r21)

OCU:

100344047

OPI:	101536350(PPP1R21)

TUP:	102485820(PPP1R21)

GVR:	103601937(PPP1R21)

CFA:	474586(PPP1R21)

CLUD:

112671965(PPP1R21)

VVP:	112915234(PPP1R21)

VLG:	121491495(PPP1R21)

NPO:	129511969(PPP1R21)

AML:	100478278(PPP1R21)

UMR:	103671769(PPP1R21)

UAH:	113245901(PPP1R21)

UAR:	123785915(PPP1R21)

ELK:

111148028

LLV:

125108529

MPUF:

101692807(PPP1R21)

MNP:	132021563(PPP1R21)

MLK:	131808602(PPP1R21)

NVS:	122916465(PPP1R21)

ORO:	101370326(PPP1R21)

EJU:	114209804(PPP1R21)

ZCA:	113937132(PPP1R21)

MLX:	118008148(PPP1R21)

NSU:	110590416(PPP1R21)

LWW:	102739324(PPP1R21)

FCA:	101082997(PPP1R21)

PYU:	121016307(PPP1R21)

PCOO:

112868913(PPP1R21)

PBG:	122496827(PPP1R21)

PVIV:

125162108(PPP1R21)

LRUF:

124503203

LGF:	123580765(PPP1R21)

AJU:

106977189

PTG:	102953412(PPP1R21)

PPAD:

109247480(PPP1R21)

PUC:

125936985

PLEZ:

122216035(PPP1R21)

HHV:	120241016(PPP1R21)

BTA:	513495(PPP1R21)

BOM:	102283427(PPP1R21)

BIU:	109565540(PPP1R21)

BBUB:

102405500(PPP1R21)

BBIS:

105000185(PPP1R21)

CHX:	102174309(PPP1R21)

OAS:	101106669(PPP1R21)

BTAX:

128055877(PPP1R21)

CSUM:

138075267(PPP1R21)

ODA:	120851757(PPP1R21)

CCAD:

122441657(PPP1R21)

MREE:

136164397(PPP1R21)

OVR:	110137623(PPP1R21)

MBEZ:

129539078(PPP1R21)

SSC:	100520130(PPP1R21)

CFR:	102514232(PPP1R21)

CBAI:

105079042(PPP1R21)

CDK:	105092353(PPP1R21)

VPC:	102534860(PPP1R21)

BACU:

102998301(PPP1R21)

BMUS:

118906371(PPP1R21)

LVE:	103089886(PPP1R21)

OOR:	101270255(PPP1R21)

LALB:

132531538(PPP1R21)

DLE:	111174780(PPP1R21)

PCAD:

102991613(PPP1R21)

PSIU:

116763920(PPP1R21)

NASI:

112405220(PPP1R21)

ECB:	100053007(PPP1R21)

EPZ:	103556906(PPP1R21)

EAI:	106835509(PPP1R21)

MYB:	102246734(PPP1R21)

MYD:	102754409(PPP1R21)

MMYO:

118669017(PPP1R21)

MLF:	102427583(PPP1R21)

MDT:	132213380(PPP1R21)

MYUM:

139019887(PPP1R21)

PKL:	118717343(PPP1R21)

EFUS:

103305409(PPP1R21)

MNA:	107544320(PPP1R21)

DRO:	112297927(PPP1R21)

SHON:

118988365(PPP1R21)

AJM:	119060881(PPP1R21)

PDIC:

114499578(PPP1R21)

PHAS:

123811493(PPP1R21)

MMF:	118630642(PPP1R21)

PPAM:

129072068(PPP1R21)

HAI:	109389913(PPP1R21)

RFQ:	117033247(PPP1R21)

PALE:

102892504(PPP1R21)

PGIG:

120621656(PPP1R21)

PVP:	105292905(PPP1R21)

RAY:	107506444(PPP1R21)

MJV:	108406522(PPP1R21)

TOD:	119259317(PPP1R21)

SARA:

101542885(PPP1R21)

SFUM:

130024094(PPP1R21)

SETR:

126023925(PPP1R21)

LAV:	100676255(PPP1R21)

TMU:

101344917

ETF:	101640334(PPP1R21)

DNM:	101435008(PPP1R21)

MDO:	100033353(PPP1R21)

GAS:	123236853(PPP1R21)

SHR:	100926013(PPP1R21)

AFZ:

127548066

PCW:	110218521(PPP1R21)

TVP:	118843442(PPP1R21)

PBRV:

138148821(PPP1R21)

OAA:	100084298(PPP1R21)

TACU:

119932233(PPP1R21)

GGA:	421287(PPP1R21)

PCOC:

116232536(PPP1R21)

MGP:	100541651(PPP1R21)

CJO:	107310879(PPP1R21)

TPAI:

128077755(PPP1R21)

LMUT:

125689047(PPP1R21)

NMEL:

110397022(PPP1R21)

APLA:

101799956(PPP1R21)

ACYG:

106043142(PPP1R21)

CATA:

118257345(PPP1R21)

AFUL:

116487554(PPP1R21)

TGU:	100231538(PPP1R21)

LSR:	110475810(PPP1R21)

SCAN:

103819210(PPP1R21)

PMOA:

120501265(PPP1R21)

OTC:	121346350(PPP1R21)

PRUF:

121365298(PPP1R21)

ATRC:

139588222(PPP1R21)

GFR:	102031734(PPP1R21)

FAB:	101813887(PPP1R21)

OMA:	130251302(PPP1R21)

PHI:	102103671(PPP1R21)

PMAJ:

107202148(PPP1R21)

CCAE:

111926316(PPP1R21)

CCW:	104685593(PPP1R21)

CBRC:

103612669(PPP1R21)

ACOE:

138107757(PPP1R21)

ETL:	114060419(PPP1R21)

ZAB:	102061619(PPP1R21)

ZLE:	135446014(PPP1R21)

ACHL:

103803735(PPP1R21)

SVG:	106853918(PPP1R21)

MMEA:

130585336(PPP1R21)

HRT:	120750313(PPP1R21)

SATI:

136359592(PPP1R21)

CCIC:

134042730(PPP1R21)

FPG:	101921366(PPP1R21)

FCH:	102051317(PPP1R21)

CCRI:

104161675(PPP1R21)

NNT:	104402998(PPP1R21)

SHAB:

115613567(PPP1R21)

ACUN:

113478231(PPP1R21)

TALA:

104361449(PPP1R21)

ACHC:

115349755(PPP1R21)

HALD:

104321841(PPP1R21)

HLE:	104838171(PPP1R21)

AGEN:

126052641

HHAR:

128149968(PPP1R21)

GCL:

127014763

CSTI:

104554001(PPP1R21)

LDI:	104342843(PPP1R21)

MNB:	103778377(PPP1R21)

DPUB:

104305284(PPP1R21)

PPUS:

135186571(PPP1R21)

AVIT:

104270645(PPP1R21)

BRHI:

104501891(PPP1R21)

EGZ:	104134626(PPP1R21)

NNI:	104018108(PPP1R21)

PCRI:

104030103(PPP1R21)

PCAO:

104039825(PPP1R21)

PADL:

103924989(PPP1R21)

AFOR:

103893540(PPP1R21)

FGA:	104073200(PPP1R21)

GSTE:

104255410(PPP1R21)

CBOY:

140649632(PPP1R21)

CLV:	102086083 102091089

MUI:	104535978(PPP1R21)

PGUU:

104462028(PPP1R21)

PLET:

104620267(PPP1R21)

EHS:	104503824(PPP1R21)

CMAC:

104483234(PPP1R21)

CUCA:

104060717(PPP1R21)

TEO:	104377059(PPP1R21)

BREG:

104639583(PPP1R21)

OHA:	104331944(PPP1R21)

ACAR:

104523044(PPP1R21)

CPEA:

104395289(PPP1R21)

CVF:	104295111(PPP1R21)

RTD:	128906791(PPP1R21)

CRID:

134512606(PPP1R21)

AAM:	106490448(PPP1R21)

AROW:

112974928(PPP1R21)

NPD:	112954813(PPP1R21)

TGT:	104565015(PPP1R21)

DNE:	112980511(PPP1R21)

SCAM:

104153991(PPP1R21)

ASN:	102372010(PPP1R21)

AMJ:	102569003(PPP1R21)

CPOO:

109319624(PPP1R21)

GGN:	109296749(PPP1R21)

PSS:	102463095(PPP1R21)

CMY:	102943136(PPP1R21)

CCAY:

125633537(PPP1R21)

DCC:	119853225(PPP1R21)

CPIC:

101943876(PPP1R21)

TST:	117874336(PPP1R21)

CABI:

116818315(PPP1R21)

MRV:	120402224(PPP1R21)

ACS:	100561019(ppp1r21)

ASAO:

132761571(PPP1R21)

PVT:	110079574(PPP1R21)

SUND:

121929614(PPP1R21)

PBI:	103052294(PPP1R21)

PMUR:

107290121(PPP1R21)

CTIG:

120307124(PPP1R21)

TSR:	106541528(PPP1R21)

PGUT:

117671527(PPP1R21)

APRI:

131189122(PPP1R21)

PTEX:

113433417(PPP1R21)

NSS:	113423404(PPP1R21)

VKO:	123022702(PPP1R21)

PMUA:

114594853(PPP1R21)

PRAF:

128411337(PPP1R21)

ZVI:	118083053(PPP1R21)

HCG:	128322542(PPP1R21)

GJA:	107124251(PPP1R21)

STOW:

125445844(PPP1R21)

EMC:	129333897(PPP1R21)

XLA:	108717743 432064(ppp1r21.L)

XTR:	100493219(ppp1r21)

NPR:	108787594(PPP1R21)

RTEM:

120937991(PPP1R21)

BBUF:

120999421(PPP1R21)

BGAR:

122934445(PPP1R21)

PWL:	138295637(PPP1R21)

MUO:	115465391(PPP1R21)

GSH:	117357333(PPP1R21)

DRE:	492333(ppp1r21)

SRX:	107716874(ppp1r21) 107749695

SANH:

107683724 107695191

SGH:

107570315

CCAR:

109073659(ppp1r21)

CAUA:

113057334(ppp1r21)

CGIB:

127970131

PTET:

122356444(ppp1r21)

LROH:

127175033(ppp1r21)

OMC:	131552821(ppp1r21)

PPRM:

120484236(ppp1r21)

RKG:	130090948(ppp1r21)

MAMB:

125277584(ppp1r21)

CIDE:

127525047

CERY:

137020839(ppp1r21)

MASI:

127413742

TROS:

130558865(ppp1r21)

MANU:

129416347(ppp1r21)

PDAB:

135732534(ppp1r21)

IPU:

108260726

IFU:	128604313(ppp1r21)

PHYP:

113545704(ppp1r21)

SMEO:

124381604(ppp1r21)

TFD:	113650067(ppp1r21)

TVC:	132841689(ppp1r21)

CGAR:

128508577(ppp1r21)

NGRA:

132883478(ppp1r21)

TRN:	134326636(ppp1r21)

AMEX:

103038888(ppp1r21)

CMAO:

118816643(ppp1r21)

EEE:	113591113(ppp1r21)

CHAR:

105905002(ppp1r21)

SPIL:

134063841(ppp1r21)

TRU:	101078597(ppp1r21)

TFS:	130533321(ppp1r21)

TNG:	GSTEN00030754G001

LCO:	104918669(ppp1r21)

NCC:	104951342(ppp1r21)

TBEN:

117499648(ppp1r21)

CGOB:

115020341(ppp1r21)

PGEO:

117459710(ppp1r21)

GACU:

117542186(ppp1r21)

EMAC:

134858977(ppp1r21)

ELY:	117248585(ppp1r21)

EFO:	125903646(ppp1r21)

PLEP:

121954752(ppp1r21)

SLUC:

116052107(ppp1r21)

ECRA:

117960067(ppp1r21)

ESP:	116674390 116705599(ppp1r21)

PFLV:

114572254(ppp1r21)

GAT:	120821103(ppp1r21)

PPUG:

119214290(ppp1r21)

AFB:	129092064(ppp1r21)

CLUM:

117743917(ppp1r21)

PSWI:

130207261(ppp1r21)

CANA:

137780066(ppp1r21)

CVE:	137882323(ppp1r21)

MSAM:

119917512(ppp1r21)

SCHU:

122884307(ppp1r21)

CUD:	121510976(ppp1r21)

SPUL:

138588725(ppp1r21)

LMIX:

132975174(ppp1r21)

ALAT:

119033898(ppp1r21)

ASTR:

137604046(ppp1r21)

MZE:	101468409(ppp1r21)

ONL:	100703325(ppp1r21)

OAU:	116314172(ppp1r21)

OLA:	101160260(ppp1r21)

OML:	112161960(ppp1r21)

CSAI:

133463350(ppp1r21)

XMA:	102228905(ppp1r21)

XCO:	114138279(ppp1r21)

XHE:	116713035(ppp1r21)

PRET:

103477046(ppp1r21)

PFOR:

103134107(ppp1r21)

PLAI:

106957027(ppp1r21)

PMEI:

106931636(ppp1r21)

GAF:	122842584(ppp1r21)

PPRL:

129359503(ppp1r21)

CVG:	107089301(ppp1r21)

CTUL:

119780197(ppp1r21)

GMU:	124859189(ppp1r21)

NFU:	107375750(ppp1r21)

KMR:	108234109(ppp1r21)

ALIM:

106515898(ppp1r21)

NWH:	119417882(ppp1r21)

AOCE:

111567194(ppp1r21)

EJA:	138195473(ppp1r21)

BFRE:

138616126(ppp1r21)

MCEP:

125018544(ppp1r21)

CSEM:

103387558(ppp1r21)

POV:	109635121(ppp1r21)

SSEN:

122781547(ppp1r21)

SSOE:

131474240(ppp1r21)

HHIP:

117775473(ppp1r21)

HSP:	118118683(ppp1r21)

PPLT:

128453881(ppp1r21)

SMAU:

118283879(ppp1r21)

LCF:

108894387

SDU:	111220680(ppp1r21)

SLAL:

111658966(ppp1r21)

XGL:	120796653(ppp1r21)

HCQ:	109516164(ppp1r21)

SSCV:

125978055(ppp1r21)

SBIA:

133510158(ppp1r21)

PEE:	133409710(ppp1r21)

PTAO:

133485637(ppp1r21)

BPEC:

110157101(ppp1r21)

ENY:	140350944(ppp1r21)

MALB:

109961970(ppp1r21)

BSPL:

114870533(ppp1r21)

SJO:	128372814(ppp1r21)

SSCO:

133991937(ppp1r21)

GMH:	115559769(ppp1r21)

SASA:

106589739(ppp1r21) 106611138

STRU:

115152812 115200820

OTW:	112224598 112260213

OMY:	110499323 110503012

OGO:	124038643 124040310

ONE:	115112837 115144379(ppp1r21)

OKI:	109878857(ppp1r21) 109900103

OKE:	118396697 118402804

OMM:	135511866 135523504

OCLA:

139376884 139381216

SALP:

111968063(ppp1r21) 111978140

SNH:	120029539 120046861

CCLU:

121547679 121556636

ELS:	105028412(ppp1r21)

OEP:	134021840(ppp1r21)

SFM:	108918130(ppp1r21)

PKI:	111848829(ppp1r21)

AANG:

118218488(ppp1r21)

AROT:

135245144(ppp1r21)

CCOG:

133118306(ppp1r21)

LOC:	102692569(ppp1r21)

PSPA:

121316699(ppp1r21)

ARUT:

117402857 117411398(ppp1r21)

PSEX:

120516480(ppp1r21)

LCM:	102364373(PPP1R21)

CMK:	103180789(ppp1r21)

CPLA:

122552716(ppp1r21)

HOC:	132819376(ppp1r21)

LERI:

129699627(ppp1r21)

PMRN:

116943386(PPP1R21)

LRJ:	133342212(PPP1R21)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG6607(CG6607)

DER:

6554648

DSE:

6607761

DSI:	Dsimw501_GD15182(Dsim_GD15182)

DYA:	Dyak_GE23495

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10086

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119678403 119679167

MDE:	101899671 131801908

SCAC:

LCQ:

LSQ:

CVJ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

109414742 109430017 115267369

ASUA:

134225500

CQU:	CpipJ_CPIJ016036

CPII:

CBRI:

CNS:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

AGRG:

ATD:

HAXR:

DVV:

NVL:

BMOR:

BMAN:

MSEX:

DPL:	KGM_214626

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CCRN:

API:	100163822 100574023

AGS:

RMD:

BTAB:

DCI:

NLU:	111046135 120351002

HVI:

124373621

MQU:

129001341

PHU:	Phum_PHUM513960

FOC:

113205417

TPAL:

117643491

ZNE:	110829989 110829992

CSEC:

PAME:

BROR:

IEL:

HAMR:

FCD:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

DPTE:

DFR:

CSCU:

CVS:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_F33E11.3(F33E11.3)

CBR:

CBG_12107

CRQ:	GCK72_020806

BMY:	BM_BM9385(Bm9385)

LOA:	LOAG_18046

TSP:

Tsp_03086

HRO:	HELRODRAFT_194253

LGI:	LOTGIDRAFT_201851

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106174669 106180802

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130629502 130629519 130629541

RES:

135681443

AQU:	100636294 105312897

MBR:	MONBRDRAFT_36101

SRE:	PTSG_03015

DDI:	DDB_G0285439

DPP:	DICPUDRAFT_157996

DFA:

DFA_02194

ACAN:

ACA1_279460

NGR:	NAEGRDRAFT_58885

» show all

Reference

PMID:19389623

Authors

Hendrickx A, Beullens M, Ceulemans H, Den Abt T, Van Eynde A, Nicolaescu E, Lesage B, Bollen M

Title

Docking motif-guided mapping of the interactome of protein phosphatase-1.

Journal

Chem Biol 16:365-71 (2009)
DOI:10.1016/j.chembiol.2009.02.012

Sequence

[hsa:129285]

LinkDB

DBGET integrated database retrieval system