KEGG   ORTHOLOGY: K18090
Entry
K18090            Tight     KO                                     
Symbol
todA, tcbAd
Name
benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component [EC:1.18.1.3 1.18.1.-]
Pathway
map00361  Chlorocyclohexane and chlorobenzene degradation
map00362  Benzoate degradation
map00623  Toluene degradation
map00625  Chloroalkane and chloroalkene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00547  Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
Reaction
R03543  benzene,NADH:oxygene 1,2-oxidoreductase
R03559  toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R05429  1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R06831  1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R06856  chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R09151  trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming)
R09152  trichloroethene,NADH:oxygen oxidoreductase (formate-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
   00625 Chloroalkane and chloroalkene degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
   00361 Chlorocyclohexane and chlorobenzene degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
   00623 Toluene degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.18  Acting on iron-sulfur proteins as donors
   1.18.1  With NAD+ or NADP+ as acceptor
    1.18.1.3  ferredoxin---NAD+ reductase
     K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18090
Other DBs
COG: COG0446
GO: 0008860
Genes
PPF: Pput_2878
PPX: T1E_4269(tobA)
PMON: X969_10945
PMOT: X970_10600
PASI: LG197_17465
BPT: Bpet3741
ATEM: PQV96_18695
AG: AAC43635(tcbAd)
Reference
PMID:8626733
  Authors
Werlen C, Kohler HP, van der Meer JR
  Title
The broad substrate chlorobenzene dioxygenase and cis-chlorobenzene dihydrodiol dehydrogenase of Pseudomonas sp. strain P51 are linked evolutionarily to the enzymes for benzene and toluene degradation.
  Journal
J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009
  Sequence
[ag:AAC43635]
LinkDB

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