KEGG   ORTHOLOGY: K18251
Entry
K18251                      KO                                     
Symbol
phtAa
Name
phthalate 3,4-dioxygenase subunit alpha [EC:1.14.12.-]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Reaction
R09227  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K18251  phtAa; phthalate 3,4-dioxygenase subunit alpha
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18251
Genes
MMC: Mmcs_1622
MKM: Mkms_1647
MJL: Mjls_1595
MYE: AB431_15695
MVA: Mvan_0463
MGI: Mflv_0595 Mflv_0685
MSP: Mspyr1_01400
MRH: MycrhN_3142
MGAD: MGAD_32330(hcaE_4)
MMON: EWR22_08275
MPAE: K0O64_27630
MCRO: MI149_00600
 » show all
Reference
PMID:15313184
  Authors
Stingley RL, Khan AA, Cerniglia CE.
  Title
Molecular characterization of a phenanthrene degradation pathway in Mycobacterium vanbaalenii PYR-1.
  Journal
Biochem Biophys Res Commun 322:133-46 (2004)
DOI:10.1016/j.bbrc.2004.07.089
  Sequence
[mva:Mvan_0463]
LinkDB

KEGG   ORTHOLOGY: K18252
Entry
K18252                      KO                                     
Symbol
phtAb
Name
phthalate 3,4-dioxygenase subunit beta [EC:1.14.12.-]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Reaction
R09227  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K18252  phtAb; phthalate 3,4-dioxygenase subunit beta
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18252
Genes
MMC: Mmcs_1623
MKM: Mkms_1648
MJL: Mjls_1596
MYE: AB431_15690
MNM: MNVM_33400
MVA: Mvan_0464
MGI: Mflv_0594 Mflv_0684
MSP: Mspyr1_01410
MRH: MycrhN_3143
MGAD: MGAD_32320 MGAD_51230
MMON: EWR22_08280
MPAE: K0O64_27625
MCRO: MI149_00605
MMIN: MMIN_04040
MHIB: MHIB_21350
ACTQ: OG417_48710
AACD: LWP59_17915
ACTY: OG774_28185
SBAE: DSM104329_01708(bphE_1)
 » show all
Reference
PMID:15313184
  Authors
Stingley RL, Khan AA, Cerniglia CE.
  Title
Molecular characterization of a phenanthrene degradation pathway in Mycobacterium vanbaalenii PYR-1.
  Journal
Biochem Biophys Res Commun 322:133-46 (2004)
DOI:10.1016/j.bbrc.2004.07.089
  Sequence
[mva:Mvan_0464]
LinkDB

KEGG   ORTHOLOGY: K18253
Entry
K18253                      KO                                     
Symbol
phtAc
Name
phthalate 3,4-dioxygenase ferredoxin component
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Reaction
R09227  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K18253  phtAc; phthalate 3,4-dioxygenase ferredoxin component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18253
Genes
MGI: Mflv_0591 Mflv_0681
MSP: Mspyr1_01440
MRH: MycrhN_3146
Reference
PMID:15313184
  Authors
Stingley RL, Khan AA, Cerniglia CE.
  Title
Molecular characterization of a phenanthrene degradation pathway in Mycobacterium vanbaalenii PYR-1.
  Journal
Biochem Biophys Res Commun 322:133-46 (2004)
DOI:10.1016/j.bbrc.2004.07.089
LinkDB

KEGG   ORTHOLOGY: K18254
Entry
K18254                      KO                                     
Symbol
phtAd
Name
phthalate 3,4-dioxygenase ferredoxin reductase component [EC:1.18.1.3]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Reaction
R09227  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K18254  phtAd; phthalate 3,4-dioxygenase ferredoxin reductase component
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.18  Acting on iron-sulfur proteins as donors
   1.18.1  With NAD+ or NADP+ as acceptor
    1.18.1.3  ferredoxin---NAD+ reductase
     K18254  phtAd; phthalate 3,4-dioxygenase ferredoxin reductase component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18254
Other DBs
COG: COG0446
GO: 0008860
Genes
MMC: Mmcs_1625
MKM: Mkms_1651
MJL: Mjls_1599
MYE: AB431_15670
MADI: A7U43_01750
MVA: Mvan_0467
MGI: Mflv_0590 Mflv_0680
MSP: Mspyr1_01450
MRH: MycrhN_3147
MGAD: MGAD_32280
MMON: EWR22_08300
MPAE: K0O64_27605
MCRO: MI149_00625
ROZ: CBI38_00635
GOS: QAD21_13230
GSI: P5P27_04640
PDEL: JCQ34_20525 JCQ34_20680
NCX: Nocox_41395(thcD5)
 » show all
Reference
PMID:15313184
  Authors
Stingley RL, Khan AA, Cerniglia CE.
  Title
Molecular characterization of a phenanthrene degradation pathway in Mycobacterium vanbaalenii PYR-1.
  Journal
Biochem Biophys Res Commun 322:133-46 (2004)
DOI:10.1016/j.bbrc.2004.07.089
  Sequence
[mva:Mvan_0467]
LinkDB

KEGG   REACTION: R09227
Entry
R09227                      Reaction                               
Definition
Phthalate + Oxygen + NADH + H+ <=> Phthalate 3,4-cis-dihydrodiol + NAD+
Equation
C01606 + C00007 + C00004 + C00080 <=> C18314 + C00003
Comment
phthalate 3,4-dioxygenase
Reaction class
RC00001  C00003_C00004
RC00098  C01606_C18314
Enzyme
1.14.12.-
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.-
     R09227  Phthalate + Oxygen + NADH + H+ <=> Phthalate 3,4-cis-dihydrodiol + NAD+
Orthology
K18251  phthalate 3,4-dioxygenase subunit alpha [EC:1.14.12.-]
K18252  phthalate 3,4-dioxygenase subunit beta [EC:1.14.12.-]
K18253  phthalate 3,4-dioxygenase ferredoxin component
K18254  phthalate 3,4-dioxygenase ferredoxin reductase component [EC:1.18.1.3]
LinkDB

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