KEGG   ORTHOLOGY: K18297
Entry
K18297                      KO                                     
Symbol
mexT
Name
LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
Module
M00641  Multidrug resistance, efflux pump MexEF-OprN
M00745  Imipenem resistance, repression of porin OprD
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K18297  mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18297  mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
Transcription factors [BR:ko03000]
 Prokaryotic type
  Helix-turn-helix
   LysR family
    K18297  mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  beta-Lactam resistance modules
   Imipenem resistance, repression of porin OprD
    K18297  mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexEF-OprN
    K18297  mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
Other DBs
COG: COG0583
Genes
PAE: PA2492(mexT)
PAEV: N297_2563
PAEI: N296_2563
PAU: PA14_32410(mexT)
PAP: PSPA7_2746(mexT)
PAF: PAM18_2547(mexT)
PNC: NCGM2_3495(mexT)
PAEB: NCGM1900_4037(mexT)
PDK: PADK2_12785
PRP: M062_12965
PAEP: PA1S_13185
PAER: PA1R_gp0286
PAEM: U769_12765
PAEL: T223_14385
PAES: SCV20265_2818
PAEU: BN889_04604(mexT)
PAEG: AI22_20735
PAEC: M802_2560
PMY: Pmen_1157 Pmen_2183 Pmen_2201
PMK: MDS_2532 MDS_2697
PRE: PCA10_27290 PCA10_30610(mexT) PCA10_30680 PCA10_31950(mexT)
PPSE: BN5_2054(mexT1)
PFUW: KF707C_25820 KF707C_43580
PALC: A0T30_10095 A0T30_12370
PCQ: PcP3B5_29940(leuO_2)
PMUI: G4G71_16940 G4G71_17780
PNT: G5B91_14460 G5B91_15220
PPAA: B7D75_12720
PPU: PP_2074 PP_2826(mexT) PP_3669
PPF: Pput_2060 Pput_2863 Pput_3669
PPG: PputGB1_1584 PputGB1_2230 PputGB1_2956
PPW: PputW619_2234 PputW619_2978
PPT: PPS_1640 PPS_2427 PPS_3173
PPB: PPUBIRD1_2058 PPUBIRD1_2908(ttgS) PPUBIRD1_3581
PPI: YSA_01645 YSA_09475 YSA_09870
PPX: T1E_1751 T1E_3624 T1E_4286 T1E_5547
PPUH: B479_12100 B479_15740
PPUT: L483_12050
PPUN: PP4_21240 PP4_29910(mexT) PP4_37790
PPUD: DW66_1928 DW66_2685 DW66_3442
PFV: Psefu_0907 Psefu_2360
PMON: X969_06250 X969_11015 X969_15255
PMOT: X970_06225 X970_10670 X970_14900
PPJ: RK21_01465 RK21_02418 RK21_03361
POR: APT59_01200 APT59_02705
PMOL: CLJ08_01485
PALD: LU682_011650 LU682_016500 LU682_020630
PIX: RIN61_01080 RIN61_24155
PMOS: O165_007425
PST: PSPTO_3040 PSPTO_3265
PSB: Psyr_2913 Psyr_3102
PSYR: N018_11005 N018_11930
PSP: PSPPH_2309(mexT) PSPPH_3014
PSAV: PSA3335_13800 PSA3335_14900
PAMG: BKM19_018215
PCI: PCH70_19960 PCH70_23450 PCH70_28080
PAVL: BKM03_12675 BKM03_13755
PVD: CFBP1590__2933 CFBP1590__3106 CFBP1590__3173
PCAB: JGS08_11410
PCOF: POR16_13100 POR16_13870
PTRE: I9H09_11195
PSYI: MME58_14900 MME58_15895
PAST: N015_11555 N015_12685 N015_15400
PLIJ: KQP88_09545 KQP88_11265
PFL: PFL_1484 PFL_3233(mexT)
PPRC: PFLCHA0_c15230(nahR2) PFLCHA0_c32630(nahR6)
PPRO: PPC_1537 PPC_3258
PFE: PSF113_1439 PSF113_2135 PSF113_2769(mexT) PSF113_3820
PFN: HZ99_02940 HZ99_25160
PFO: Pfl01_1383 Pfl01_1962 Pfl01_2460 Pfl01_2666
PFS: PFLU_1498 PFLU_3161 PFLU_3706
PFC: PflA506_1512 PflA506_2601(mexT) PflA506_3073
PPZ: H045_04060 H045_07980 H045_10460
PFB: VO64_0223 VO64_4634 VO64_5635
PMAN: OU5_0332(mexT) OU5_1967 OU5_5736 OU5_5775 OU5_6047
PTV: AA957_00390 AA957_06625 AA957_27020
PCG: AXG94_02655 AXG94_03275 AXG94_05550 AXG94_22700
PVR: PverR02_07675 PverR02_12800 PverR02_14815 PverR02_14850
PAZO: AYR47_14750 AYR47_19600 AYR47_21995 AYR47_25080
POI: BOP93_07200 BOP93_10480 BOP93_12030
PRX: HRH33_08150 HRH33_15685
PMED: E3Z27_07090 E3Z27_13775 E3Z27_15590 E3Z27_17895
PKR: AYO71_09565 AYO71_13140 AYO71_17320
PMUD: NCTC8068_01379(nodD2_3) NCTC8068_02456(leuO)
PTOL: I7845_07395
PFW: PF1751_v1c14790 PF1751_v1c26030 PF1751_v1c31440
PFF: PFLUOLIPICF700935 PFLUOLIPICF720500 PFLUOLIPICF723335
PFX: A7318_06650 A7318_13735 A7318_15130
PEN: PSEEN2629
PLUL: FOB45_15055
PBA: PSEBR_a1360 PSEBR_a2717 PSEBR_a3024 PSEBR_a3602
PBC: CD58_11000 CD58_15180
PPUU: PputUW4_01291 PputUW4_01928 PputUW4_02537 PputUW4_03308
PDR: H681_04805 H681_10175 H681_14450
PSV: PVLB_10985 PVLB_13900
PSK: U771_08615 U771_17100 U771_19495
PKC: PKB_2904 PKB_4306 PKB_4376
PCH: EY04_06870 EY04_16240 EY04_18360
PCZ: PCL1606_25730 PCL1606_27990 PCL1606_46390
PCP: JM49_12735 JM49_14420 JM49_22995
PCHP: C4K32_1546 C4K32_3361 C4K32_3679
PFZ: AV641_11285
PLQ: AA042_20300
PALK: PSAKL28_22990
PRH: LT40_11670 LT40_16960
PSW: LK03_18400
PPV: NJ69_08450
PSES: PSCI_4242 PSCI_4624 PSCI_5198
PSEM: TO66_07340 TO66_16925 TO66_18540
PSEC: CCOS191_3006
PPSY: AOC04_08365
PSOS: POS17_1495 POS17_2843
PFK: PFAS1_00400 PFAS1_18565 PFAS1_20335 PFAS1_26465
PANR: A7J50_1620 A7J50_2770
PPSL: BJP27_13085 BJP27_17100
PSET: THL1_2408 THL1_658
PSIL: PMA3_10765 PMA3_13625 PMA3_17705 PMA3_22380
PYM: AK972_2988 AK972_3396 AK972_4480
PKE: DLD99_07655 DLD99_10660 DLD99_13975
PALL: UYA_12275 UYA_13595
PUM: HGP31_07435 HGP31_12295 HGP31_16140 HGP31_19560
POJ: PtoMrB4_22480 PtoMrB4_26580
PGG: FX982_03679 FX982_04190 FX982_04531
PPSH: G5J76_14455
PGY: AWU82_02845 AWU82_13865 AWU82_14855 AWU82_23295
PLAL: FXN65_06495 FXN65_12195 FXN65_14190
PSEJ: HNQ25_11815
PVK: EPZ47_15245 EPZ47_18320
PEZ: HWQ56_01220 HWQ56_16235
PBZ: GN234_03565 GN234_11040 GN234_28955
PKH: JLK41_14150
PTY: JWV26_23480
PMAO: PMYSY11_2231 PMYSY11_3219
PATA: JWU58_17095 JWU58_20680
PZE: HU754_008420 HU754_019185
PMOE: HV782_007885 HV782_011140
PSEP: C4K39_1563 C4K39_2934
PPII: QL104_07795 QL104_14605
PVW: HU752_008495 HU752_014870 HU752_018840
PTRT: HU722_0008480 HU722_0012730
PXA: KSS93_18410
PSAM: HU731_003690 HU731_023290
PTZ: HU718_008080 HU718_011325 HU718_014025
PSHH: HU773_007630
PHV: HU739_002680 HU739_007470 HU739_010665
PPRG: HU725_009650
PANH: HU763_014240
PASG: KSS96_08135 KSS96_16775
PFAK: KSS94_11800 KSS94_13995
PAZE: KSS91_07360 KSS91_10405 KSS91_17985
PALV: KSS97_15635 KSS97_19040 KSS97_21735
PORY: EJA05_11280 EJA05_15105
PTK: EXN22_13230
PTW: TUM18999_33560 TUM18999_35950
PZA: HU749_008390 HU749_016745 HU749_019135
PIE: HU724_007640 HU724_010955 HU724_013670
PTAE: NCTC10697_02181(nodD2)
PGF: J0G10_08195 J0G10_11845
PCAV: D3880_12655
PJU: L1P09_07330 L1P09_10540 L1P09_11510
PHF: NLY38_05950 NLY38_13085
PIZ: LAB08_R12940 LAB08_R19430 LAB08_R30100 LAB08_R37990 LAB08_R38560
PPEG: KUA23_07585 KUA23_11935
PSII: NF676_07330 NF676_10505 NF676_12780 NF676_14560
PSIH: LOY51_11050 LOY51_14720
PCAS: LOY40_13270 LOY40_14985 LOY40_18785 LOY40_21560
PFIT: KJY40_08085 KJY40_11640 KJY40_18205
PASI: LG197_13215 LG197_17540 LG197_21455
PKM: PZ739_12355 PZ739_16375
PNB: NK667_11470 NK667_15775 NK667_20225
PSOA: PSm6_49470 PSm6_57230
PTAI: ICN73_14545 ICN73_22365
PKK: QQ992_08255 QQ992_10720 QQ992_14525
PKJ: Q1W70_03570 Q1W70_24685
PHYG: JTY93_06770
PHOM: KJF94_03855 KJF94_07525 KJF94_11335 KJF94_14420 KJF94_18545
PCHE: QYM18_19730 QYM18_21265
PCUC: PSH97_06640 PSH97_10900 PSH97_13855
PTRL: OU419_11400
PPAE: LDL65_18820 LDL65_21560 LDL65_25180
PPAO: K3169_12875 K3169_15780 K3169_18240
PRHZ: CRX69_17025 CRX69_17350 CRX69_21595
PSJY: AA098_08815 AA098_15815 AA098_17050
PSKU: KUIN1_28300 KUIN1_30520
PSA: PST_2165(mexT)
PSZ: PSTAB_2053(mexT)
PSR: PSTAA_2196(mexT)
PSC: A458_09950
PSJ: PSJM300_09510
PSH: Psest_2146
PSTT: CH92_10500 CH92_11465
PSTU: UIB01_11095
PSED: DM292_08495
PCHL: LLJ08_10395
PBM: CL52_09675
PKG: LW136_12205
SDEG: GOM96_02035
AVN: Avin_33850(mexT)
AVL: AvCA_33850(mexT)
AVD: AvCA6_33850(mexT)
PDEN: F1C79_05745 F1C79_10230 F1C79_11595
PBAU: OS670_02460
KUY: FY550_16155
SAJS: QO259_04270
PLG: NCTC10937_02308(nodD2_1) NCTC10937_02430(nodD2_2) NCTC10937_02648(nodD2_3)
VAP: Vapar_3889
VPE: Varpa_2584
VPD: VAPA_1c40090
VBO: CKY39_18970
HYB: Q5W_14175
LABP: FJ695_16495
SECH: B18_24535
RMT: IAI58_00845
RFL: Rmf_43490
RCV: PFY06_13675
ELIO: KO353_14790
MFB: MFUL124B02_36675
 » show all
Reference
PMID:19683048
  Authors
Tian ZX, Mac Aogain M, O'Connor HF, Fargier E, Mooij MJ, Adams C, Wang YP, O'Gara F
  Title
MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump.
  Journal
Microb Pathog 47:237-41 (2009)
DOI:10.1016/j.micpath.2009.08.003
  Sequence
[pae:PA2492]
Reference
PMID:17223624
  Authors
Depardieu F, Podglajen I, Leclercq R, Collatz E, Courvalin P
  Title
Modes and modulations of antibiotic resistance gene expression.
  Journal
Clin Microbiol Rev 20:79-114 (2007)
DOI:10.1128/CMR.00015-06
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