| Entry |
|
| Symbol |
cpmB, carB
|
| Name |
|
| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
|
| Module |
| M00675 | Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate |
|
| Reaction |
| R10485 | malonyl-CoA:(S)-1-pyrroline-5-carboxylate malonyltransferase (cyclizing) |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00332 Carbapenem biosynthesis
K18317 cpmB, carB; carboxymethylproline synthase
09140 Cellular Processes
09145 Cellular community - prokaryotes
02024 Quorum sensing
K18317 cpmB, carB; carboxymethylproline synthase
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.226 carboxymethylproline synthase
K18317 cpmB, carB; carboxymethylproline synthase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
McGowan SJ, Sebaihia M, Porter LE, Stewart GS, Williams P, Bycroft BW, Salmond GP. |
| Title |
Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Stapon A, Li R, Townsend CA |
| Title |
Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline. |
| Journal |
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| LinkDB |
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