KEGG   REACTION: R10485
Entry
R10485                      Reaction                               
Name
malonyl-CoA:(S)-1-pyrroline-5-carboxylate malonyltransferase (cyclizing)
Definition
Malonyl-CoA + (S)-1-Pyrroline-5-carboxylate + H2O <=> CoA + (2S,5S)-trans-Carboxymethylproline + CO2
Equation
C00083 + C03912 + C00001 <=> C00010 + C17366 + C00011
Reaction class
RC00004  C00010_C00083
RC03182  C03912_C17366
Enzyme
2.3.1.226
Pathway
rn00332  Carbapenem biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00675  Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.226
     R10485  Malonyl-CoA + (S)-1-Pyrroline-5-carboxylate + H2O <=> CoA + (2S,5S)-trans-Carboxymethylproline + CO2
Orthology
K18317  carboxymethylproline synthase [EC:2.3.1.226]
K18583  carboxymethylproline synthase [EC:2.3.1.226]
Other DBs
RHEA: 36666
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