KEGG   ORTHOLOGY: K18652
Entry
K18652                      KO                                     
Symbol
ntdC
Name
glucose-6-phosphate 3-dehydrogenase [EC:1.1.1.361]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00877  Kanosamine biosynthesis, glucose 6-phosphate => kanosamine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K18652  ntdC; glucose-6-phosphate 3-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.361  glucose-6-phosphate 3-dehydrogenase
     K18652  ntdC; glucose-6-phosphate 3-dehydrogenase
Other DBs
RN: R10519
COG: COG0673
Genes
ECV: APECO1_O1CoBM84
YEL: LC20_02631
PQU: IG609_015980
EAM: EAMY_0625(yhjJ1)
EAY: EAM_2805(ntdC)
EPY: EpC_29580
EPR: EPYR_03199(yhjJ)
ERJ: EJP617_17780
RHEY: FEE42_05000
BSU: BSU10530(ntdC)
BSR: I33_1187
BSL: A7A1_3681
BSH: BSU6051_10530(ntdC)
BSY: I653_05325
BSUT: BSUB_01150(ntdC)
BSUL: BSUA_01150(ntdC)
BSUS: Q433_05960
BSO: BSNT_07497(yhjJ)
BSN: BSn5_17150
BSQ: B657_10530(ntdC)
BSX: C663_1077
BSP: U712_05380
BSS: BSUW23_05340(ntdC)
BST: GYO_1357
BIT: BIS30_15975
BLI: BL03982(ntdC)
BLD: BLi03944(ntdC)
BLH: BaLi_c39590(ntdC)
BSON: S101395_00445(ntdC) S101395_00446
BHT: DIC78_04340
BMOJ: HC660_11090(ntdC)
BTEQ: G4P54_05585
BAN: BA_3280
BAR: GBAA_3280
BAT: BAS3045
BAH: BAMEG_1341
BAI: BAA_3320
BAX: H9401_3122 H9401_3123
BANR: A16R_33410
BANS: BAPAT_3140
BANH: HYU01_16115
BANV: DJ46_2021
BCU: BCAH820_3271
BCX: BCA_3324
BCF: bcf_16040
BTL: BALH_2923
BTHT: H175_233p028
BTW: BF38_4420
BWD: CT694_13240
BMOB: MLA2C4_13375
BALU: QRY64_18565
BPU: BPUM_0282
BPUM: BW16_01765
BPUS: UP12_01740
BALT: CFN77_01765
BAER: BAE_09305
BSAF: BSL056_01705
BCAB: EFK13_05945(ntdC)
BACW: QR42_01720
BACY: QF06_04200
BACL: BS34A_11670(ntdC)
BALM: BsLM_1096
BZH: NF868_01580
BGI: BGM20_20540
SFF: FOB90_09085
PCHI: PC41400_15400
MAB: MAB_2612
MMV: MYCMA_1412
MABB: MASS_2570
MABL: MMASJCM_2589
MIZ: BAB75_14145
MSAO: MYCSP_09810
SMA: SAVERM_832
SHAW: CEB94_31520
SVD: CP969_03720
 » show all
Reference
PMID:23586652
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10530]
LinkDB

KEGG   ENZYME: 1.1.1.361
Entry
EC 1.1.1.361                Enzyme                                 
Name
glucose-6-phosphate 3-dehydrogenase;
ntdC (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-glucose-6-phosphate:NAD+ oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + NAD+ = 3-dehydro-D-glucose 6-phosphate + NADH + H+ [RN:R10519]
Reaction(KEGG)
R10519
Substrate
D-glucose 6-phosphate [CPD:C00092];
NAD+ [CPD:C00003]
Product
3-dehydro-D-glucose 6-phosphate [CPD:C20668];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, found in the bacterium Bacillus subtilis, is involved in a kanosamine biosynthesis pathway.
History
EC 1.1.1.361 created 2013
Pathway
ec00998  Biosynthesis of various antibiotics
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K18652  glucose-6-phosphate 3-dehydrogenase
Genes
ECV: APECO1_O1CoBM84
YEL: LC20_02631
PQU: IG609_015980
EAM: EAMY_0625(yhjJ1)
EAY: EAM_2805(ntdC)
EPY: EpC_29580
EPR: EPYR_03199(yhjJ)
ERJ: EJP617_17780
RHEY: FEE42_05000
BSU: BSU10530(ntdC)
BSR: I33_1187
BSL: A7A1_3681
BSH: BSU6051_10530(ntdC)
BSY: I653_05325
BSUT: BSUB_01150(ntdC)
BSUL: BSUA_01150(ntdC)
BSUS: Q433_05960
BSO: BSNT_07497(yhjJ)
BSN: BSn5_17150
BSQ: B657_10530(ntdC)
BSX: C663_1077
BSP: U712_05380
BSS: BSUW23_05340(ntdC)
BST: GYO_1357
BIT: BIS30_15975
BLI: BL03982(ntdC)
BLD: BLi03944(ntdC)
BLH: BaLi_c39590(ntdC)
BSON: S101395_00445(ntdC) S101395_00446
BHT: DIC78_04340
BMOJ: HC660_11090(ntdC)
BTEQ: G4P54_05585
BAN: BA_3280
BAR: GBAA_3280
BAT: BAS3045
BAH: BAMEG_1341
BAI: BAA_3320
BAX: H9401_3122 H9401_3123
BANR: A16R_33410
BANS: BAPAT_3140
BANH: HYU01_16115
BANV: DJ46_2021
BCU: BCAH820_3271
BCX: BCA_3324
BCF: bcf_16040
BTL: BALH_2923
BTHT: H175_233p028
BTW: BF38_4420
BWD: CT694_13240
BMOB: MLA2C4_13375
BALU: QRY64_18565
BPU: BPUM_0282
BPUM: BW16_01765
BPUS: UP12_01740
BALT: CFN77_01765
BAER: BAE_09305
BSAF: BSL056_01705
BCAB: EFK13_05945(ntdC)
BACW: QR42_01720
BACY: QF06_04200
BACL: BS34A_11670(ntdC)
BALM: BsLM_1096
BZH: NF868_01580
BGI: BGM20_20540
SFF: FOB90_09085
PCHI: PC41400_15400
MAB: MAB_2612
MMV: MYCMA_1412
MABB: MASS_2570
MABL: MMASJCM_2589
MIZ: BAB75_14145
MSAO: MYCSP_09810
SMA: SAVERM_832
SHAW: CEB94_31520
SVD: CP969_03720
 » show all
Reference
1  [PMID:23586652]
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10530]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.361
IUBMB Enzyme Nomenclature: 1.1.1.361
ExPASy - ENZYME nomenclature database: 1.1.1.361
BRENDA, the Enzyme Database: 1.1.1.361
LinkDB

KEGG   REACTION: R10519
Entry
R10519                      Reaction                               
Name
D-glucose-6-phosphate:NAD+ oxidoreductase
Definition
D-Glucose 6-phosphate + NAD+ <=> 3-Dehydro-D-glucose 6-phosphate + NADH + H+
Equation
C00092 + C00003 <=> C20668 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00182  C00092_C20668
Enzyme
1.1.1.361
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00877  Kanosamine biosynthesis, glucose 6-phosphate => kanosamine
Orthology
K18652  glucose-6-phosphate 3-dehydrogenase [EC:1.1.1.361]
Other DBs
RHEA: 37550
LinkDB

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