KEGG   ORTHOLOGY: K18652
Entry
K18652                      KO                                     
Symbol
ntdC
Name
glucose-6-phosphate 3-dehydrogenase [EC:1.1.1.361]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00877  Kanosamine biosynthesis, glucose 6-phosphate => kanosamine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K18652  ntdC; glucose-6-phosphate 3-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.361  glucose-6-phosphate 3-dehydrogenase
     K18652  ntdC; glucose-6-phosphate 3-dehydrogenase
Other DBs
RN: R10519
COG: COG0673
Genes
ECV: APECO1_O1CoBM84
YEL: LC20_02631
EAM: EAMY_0625(yhjJ1)
EAY: EAM_2805(ntdC)
EPY: EpC_29580
EPR: EPYR_03199(yhjJ)
ERJ: EJP617_17780
RHEY: FEE42_05000
BSU: BSU10530(ntdC)
BSR: I33_1187
BSL: A7A1_3681
BSH: BSU6051_10530(ntdC)
BSUT: BSUB_01150(ntdC)
BSUL: BSUA_01150(ntdC)
BSUS: Q433_05960
BSO: BSNT_07497(yhjJ)
BSQ: B657_10530(ntdC)
BSX: C663_1077
BSS: BSUW23_05340(ntdC)
BST: GYO_1357
BLI: BL03982(ntdC)
BLD: BLi03944(ntdC)
BLH: BaLi_c39590(ntdC)
BMOJ: HC660_11090(ntdC)
BAN: BA_3280
BAR: GBAA_3280
BAT: BAS3045
BAI: BAA_3320
BANR: A16R_33410
BANS: BAPAT_3140
BANV: DJ46_2021
BCX: BCA_3324
BCF: bcf_16040
BTL: BALH_2923
BTW: BF38_4420
BPU: BPUM_0282
BPUM: BW16_01765
BPUS: UP12_01740
BACW: QR42_01720
BACY: QF06_04200
BACL: BS34A_11670(ntdC)
BALM: BsLM_1096
MAB: MAB_2612
MABB: MASS_2570
 » show all
Reference
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10530]
LinkDB

KEGG   ENZYME: 1.1.1.361
Entry
EC 1.1.1.361                Enzyme                                 
Name
glucose-6-phosphate 3-dehydrogenase;
ntdC (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-glucose-6-phosphate:NAD+ oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + NAD+ = 3-dehydro-D-glucose 6-phosphate + NADH + H+ [RN:R10519]
Reaction(KEGG)
R10519
Substrate
D-glucose 6-phosphate [CPD:C00092];
NAD+ [CPD:C00003]
Product
3-dehydro-D-glucose 6-phosphate [CPD:C20668];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, found in the bacterium Bacillus subtilis, is involved in a kanosamine biosynthesis pathway.
History
EC 1.1.1.361 created 2013
Pathway
ec00998  Biosynthesis of various antibiotics
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K18652  glucose-6-phosphate 3-dehydrogenase
Genes
ECVAPECO1_O1CoBM84
YELLC20_02631
EAMEAMY_0625(yhjJ1)
EAYEAM_2805(ntdC)
EPYEpC_29580
EPREPYR_03199(yhjJ)
ERJEJP617_17780
RHEYFEE42_05000
BSUBSU10530(ntdC)
BSRI33_1187
BSLA7A1_3681
BSHBSU6051_10530(ntdC)
BSYI653_05325
BSUTBSUB_01150(ntdC)
BSULBSUA_01150(ntdC)
BSUSQ433_05960
BSOBSNT_07497(yhjJ)
BSNBSn5_17150
BSQB657_10530(ntdC)
BSXC663_1077
BSPU712_05380
BSSBSUW23_05340(ntdC)
BSTGYO_1357
BLIBL03982(ntdC)
BLDBLi03944(ntdC)
BLHBaLi_c39590(ntdC)
BSONS101395_00445(ntdC) S101395_00446
BHTDIC78_04340
BMOJHC660_11090(ntdC)
BTEQG4P54_05585
BANBA_3280
BARGBAA_3280
BATBAS3045
BAHBAMEG_1341
BAIBAA_3320
BAXH9401_3122 H9401_3123
BANRA16R_33410
BANSBAPAT_3140
BANHHYU01_16115
BANVDJ46_2021
BCUBCAH820_3271
BCXBCA_3324
BCFbcf_16040
BTLBALH_2923
BTHTH175_233p028
BTWBF38_4420
BWDCT694_13240
BMOBMLA2C4_13375
BPUBPUM_0282
BPUMBW16_01765
BPUSUP12_01740
BACWQR42_01720
BACYQF06_04200
BACLBS34A_11670(ntdC)
BALMBsLM_1096
BALTCFN77_01765
BSAFBSL056_01705
BITBIS30_15975
BGIBGM20_20540
SFFFOB90_09085
PCHIPC41400_15400
MABMAB_2612
MMVMYCMA_1412
MABBMASS_2570
MABLMMASJCM_2589
MIZBAB75_14145
MSAOMYCSP_09810
SMASAVERM_832
SHAWCEB94_31520
SVDCP969_03720
 » show all
Reference
1  [PMID:23586652]
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10530]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.361
IUBMB Enzyme Nomenclature: 1.1.1.361
ExPASy - ENZYME nomenclature database: 1.1.1.361
BRENDA, the Enzyme Database: 1.1.1.361
LinkDB

KEGG   REACTION: R10519
Entry
R10519                      Reaction                               
Name
D-glucose-6-phosphate:NAD+ oxidoreductase
Definition
D-Glucose 6-phosphate + NAD+ <=> 3-Dehydro-D-glucose 6-phosphate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00182  C00092_C20668
Enzyme
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00877  Kanosamine biosynthesis, glucose 6-phosphate => kanosamine
Orthology
K18652  glucose-6-phosphate 3-dehydrogenase [EC:1.1.1.361]
Other DBs
RHEA: 37550
LinkDB

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