KEGG ORTHOLOGY: K19625

ORTHOLOGY: K19625

Entry

K19625                      KO

Symbol

RLBP1

Name

retinaldehyde-binding protein 1

Disease

H00527

Retinitis pigmentosa

H00825

Familial flecked retina syndrome

H01009

Newfoundland rod-cone dystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99985 Amino acid metabolism
    K19625  RLBP1; retinaldehyde-binding protein 1

Genes

HSA:	6017(RLBP1)

PTR:	453635(RLBP1)

PPS:	100973883(RLBP1)

GGO:	101139399(RLBP1)

PON:	100433959(RLBP1)

PPYG:

129013727(RLBP1)

NLE:	100588734(RLBP1)

HMH:	116482146(RLBP1)

SSYN:

129482094(RLBP1)

MCC:	699510(RLBP1)

MCF:	102136642(RLBP1)

MTHB:

126958937

MNI:	105488336(RLBP1)

CSAB:

103231148(RLBP1)

CATY:

105592410(RLBP1)

PANU:

101019645(RLBP1)

TGE:	112628895(RLBP1)

MLEU:

105544060(RLBP1)

RRO:	104674355(RLBP1)

RBB:	108540896(RLBP1)

TFN:	117071549(RLBP1)

PTEH:

111522926(RLBP1)

CANG:

105516213(RLBP1)

CJC:	100408400(RLBP1)

SBQ:	101043485(RLBP1)

CIMI:

108295480(RLBP1)

ANAN:

105724965(RLBP1)

CSYR:

103273192(RLBP1)

MMUR:

105861879 105884711(RLBP1)

LCAT:

123645152(RLBP1)

PCOQ:

105809862(RLBP1)

OGA:	100955225(RLBP1)

MMU:	19771(Rlbp1)

MCAL:

110299013(Rlbp1)

MPAH:

110329668(Rlbp1)

RNO:	293049(Rlbp1)

MCOC:

116100598(Rlbp1)

ANU:	117719629(Rlbp1)

ASYL:

127681750(Rlbp1)

MUN:	110554397(Rlbp1)

CGE:	100754920(Rlbp1)

MAUA:

101823921(Rlbp1)

PROB:

127238136(Rlbp1)

PLEU:

114699890(Rlbp1)

MORG:

121452507(Rlbp1)

MFOT:

126508693

AAMP:

119803100(Rlbp1)

NGI:	103749915(Rlbp1)

HGL:	101699581(Rlbp1)

CPOC:

100729190(Rlbp1)

CCAN:

109687555(Rlbp1)

DORD:

105982438(Rlbp1)

DSP:	122124003(Rlbp1)

DMER:

138841844(Rlbp1)

PLOP:

125338845(Rlbp1)

NCAR:

124977638

MMMA:

107148341(Rlbp1)

ITI:	101969734(Rlbp1)

OCU:

100341313

OPI:	101517455(RLBP1)

OCZ:	121149415 121168263

TUP:	102486605(RLBP1)

GVR:	103585693(RLBP1)

CFA:	479039(RLBP1)

CLUD:

112653704(RLBP1)

VVP:	112923368(RLBP1)

VLG:	121489563(RLBP1)

NPO:	129510413(RLBP1)

AML:	100474386(RLBP1)

UMR:	103660176(RLBP1)

UAH:	113263569(RLBP1)

UAR:	123802440(RLBP1)

ELK:

111152686

LLV:

125103639

MPUF:

101688894(RLBP1)

MNP:	132029082(RLBP1)

MLK:	131835196(RLBP1)

NVS:	122893608(RLBP1)

ORO:	101379795(RLBP1)

EJU:	114223300(RLBP1)

ZCA:	113909921(RLBP1)

MLX:	118023045(RLBP1)

NSU:	110572290(RLBP1)

LWW:	102737181(RLBP1)

FCA:	101084031(RLBP1)

PYU:	121042406(RLBP1)

PCOO:

112856120(RLBP1)

PBG:	122468237(RLBP1)

PVIV:

125167480(RLBP1)

LRUF:

124517250

LGF:	123582477(RLBP1)

AJU:

106965865

PPAD:

109273425(RLBP1)

PUC:

125910721

PLEZ:

122221620(RLBP1)

HHV:	120219809(RLBP1)

BTA:	282038(RLBP1)

BOM:	102271326(RLBP1)

BIU:	109575160(RLBP1)

BBUB:

102401502(RLBP1)

BBIS:

104989376(RLBP1)

CHX:	102189433(RLBP1)

OAS:	101103269(RLBP1)

BTAX:

128066949(RLBP1)

CSUM:

138095505(RLBP1)

ODA:	120875640(RLBP1)

CCAD:

122455153(RLBP1)

MREE:

136147501(RLBP1)

OVR:	110147702(RLBP1)

MBEZ:

129550038(RLBP1)

SSC:	100521278(RLBP1)

CFR:	102506782(RLBP1)

CBAI:

105069054(RLBP1)

CDK:	105094667(RLBP1)

VPC:	102527102(RLBP1)

BACU:

103007645(RLBP1)

BMUS:

118890839(RLBP1)

LVE:	103089514(RLBP1)

OOR:	101286216(RLBP1)

LALB:

132503987(RLBP1)

GMF:	115864687(RLBP1)

DDP:	132419741(RLBP1)

DLE:	111169676(RLBP1)

PCAD:

102984343(RLBP1)

PSIU:

116749156(RLBP1)

PPHC:

136118719(RLBP1)

NASI:

112414196(RLBP1)

ECB:	100069725(RLBP1)

EPZ:	103554395(RLBP1)

EAI:	106832104(RLBP1)

MYB:	102245615(RLBP1)

MYD:	102772258(RLBP1)

MMYO:

118679284(RLBP1)

MLF:	102439618(RLBP1) 102442140

MDT:	132222982(RLBP1)

MYUM:

138998310(RLBP1)

PKL:	118704324(RLBP1)

EFUS:

103302778(RLBP1)

MNA:	107525565(RLBP1)

DRO:	112305918(RLBP1)

SHON:

118991978(RLBP1)

AJM:	119049107(RLBP1)

PDIC:

114488596(RLBP1)

PHAS:

123809798(RLBP1)

MMF:	118640976(RLBP1)

PPAM:

129073884(RLBP1)

HAI:	109381392(RLBP1)

RFQ:	117018787(RLBP1)

PALE:

102881342(RLBP1)

PGIG:

120599311(RLBP1)

PVP:	105305208(RLBP1)

RAY:	107514173(RLBP1)

MJV:	108398184(RLBP1)

TOD:	119244292(RLBP1)

SARA:

101547985(RLBP1)

SFUM:

130023349(RLBP1)

SETR:

126022394(RLBP1)

LAV:	100675583(RLBP1)

TMU:

101351203

ETF:	101649946(RLBP1)

DNM:	101421202(RLBP1)

MDO:	100016542(RLBP1)

GAS:	123236194(RLBP1)

SHR:	100932475(RLBP1)

AFZ:

127547131

PCW:	110224096(RLBP1)

TVP:	118830227(RLBP1)

PBRV:

138169263(RLBP1)

MLAO:

141520025(RLBP1)

OAA:	100082169(RLBP1)

TACU:

119928731(RLBP1)

GGA:	415492(RLBP1)

PCOC:

116225572(RLBP1)

MGP:	100546051(RLBP1)

CJO:	107318793(RLBP1)

TPAI:

128075538(RLBP1)

LMUT:

125698213(RLBP1)

NMEL:

110403767(RLBP1)

APLA:

101791685(RLBP1)

ACYG:

106036406(RLBP1)

CATA:

118252060(RLBP1)

AFUL:

116493489(RLBP1)

TGU:	100226397(RLBP1)

LSR:	110474192(RLBP1)

SCAN:

103816071(RLBP1)

PMOA:

120508930(RLBP1)

OTC:	121343528(RLBP1)

PRUF:

121354504(RLBP1)

ATRC:

139596612(RLBP1)

GFR:	102044182(RLBP1)

FAB:	101810427(RLBP1)

OMA:	130257466(RLBP1)

PHI:	102114476(RLBP1)

PMAJ:

107209202(RLBP1)

CCAE:

111933826(RLBP1)

CCW:	104683936(RLBP1)

CBRC:

103621302(RLBP1)

ACOE:

138116441(RLBP1)

ETL:	114058030(RLBP1)

ZAB:	102065152(RLBP1)

ZLE:	135452275(RLBP1)

ACHL:

103807736(RLBP1)

SVG:	106859223(RLBP1)

MMEA:

130573378(RLBP1)

HRT:	120758795(RLBP1)

SATI:

136366775(RLBP1)

CCIC:

134049303(RLBP1)

FPG:	101910894(RLBP1)

FCH:	102049344(RLBP1)

CCRI:

104157783(RLBP1)

NNT:	104405629(RLBP1)

SHAB:

115612748(RLBP1)

ACUN:

113484111(RLBP1)

TALA:

104358061(RLBP1)

ACHC:

115341207(RLBP1)

HALD:

104325499(RLBP1)

HLE:	104834551(RLBP1)

AGEN:

126043546

HHAR:

128150709(RLBP1)

GCL:

127020762

CSTI:

104553243(RLBP1)

LDI:	104349026(RLBP1)

MNB:	103777907(RLBP1)

DPUB:

104303299(RLBP1)

PPUS:

135183180(RLBP1)

AVIT:

104275218(RLBP1)

BRHI:

104501894(RLBP1)

EGZ:	104123600(RLBP1)

NNI:	104017087(RLBP1)

PCRI:

104025771(RLBP1)

PCAO:

104050381(RLBP1)

PADL:

103926326(RLBP1)

AFOR:

103896671(RLBP1)

FGA:	104073646(RLBP1)

CBOR:

142086439(RLBP1)

GSTE:

104260930(RLBP1)

CBOY:

140655551(RLBP1)

MAME:

142411966(RLBP1)

CLV:	102089364(RLBP1)

CNIC:

135992724(RLBP1)

MUI:	104539956(RLBP1)

PGUU:

104462591(RLBP1)

PLET:

104627266(RLBP1)

EHS:	104504247(RLBP1)

CMAC:

104479029(RLBP1)

CUCA:

104059695(RLBP1)

TEO:	104376169(RLBP1)

BREG:

104630831(RLBP1)

OHA:	104332082(RLBP1)

ACAR:

104518716(RLBP1)

CPEA:

104394449(RLBP1)

CVF:	104282922(RLBP1)

RTD:	128915102(RLBP1)

CRID:

134520731(RLBP1)

LMIC:

141748481(RLBP1)

AAM:	106497396(RLBP1)

AROW:

112963490(RLBP1)

NPD:	112944810(RLBP1)

TGT:	104572361(RLBP1)

DNE:	112996022(RLBP1)

SCAM:

104148199(RLBP1)

ASN:	102386275(RLBP1)

AMJ:	102575605(RLBP1)

CPOO:

109309114(RLBP1)

GGN:	109288511(RLBP1)

PSS:	102458745(RLBP1)

CIZ:	142019826(RLBP1)

CMY:	102938028(RLBP1)

CCAY:

125643292(RLBP1)

DCC:	119862570(RLBP1)

CPIC:

101941110(RLBP1)

TST:	117883485(RLBP1)

CABI:

116840116(RLBP1)

MRV:	120372894(RLBP1)

ACS:	100553532(rlbp1)

ASAO:

132762315(RLBP1)

PVT:	110072955(RLBP1)

SUND:

121934959(RLBP1)

PBI:	103062952(RLBP1)

PMUR:

107286852(RLBP1)

CTIG:

120315275(RLBP1)

TSR:	106551696(RLBP1)

PGUT:

117669875(RLBP1)

PCAE:

139324107(RLBP1)

APRI:

131184666(RLBP1)

PTEX:

113442002(RLBP1)

NSS:	113421462(RLBP1)

VKO:	123027798(RLBP1)

PMUA:

114584768(RLBP1)

PRAF:

128401831(RLBP1)

ZVI:	118093254(RLBP1)

HCG:	128335018(RLBP1)

GJA:	107122767(RLBP1)

STOW:

125424709(RLBP1)

EMC:	129345253(RLBP1)

XLA:	108712845(rlbp1.S) 380078(rlbp1.L)

XTR:	448050(rlbp1)

NPR:	108799862(RLBP1)

RTEM:

120931196(RLBP1)

ACAT:

141131314(RLBP1)

BBUF:

120987166(RLBP1)

BGAR:

122929590(RLBP1)

DTC:	141084188(RLBP1)

PWL:	138284196(RLBP1)

MUO:	115460673(RLBP1)

GSH:	117348676(RLBP1)

DRE:	393678(rlbp1a) 402990(rlbp1b)

SRX:	107737004 107753544

SANH:

107662294 107679629(rlbp1) 107685234

SGH:	107574725 107590833 107594728 107600717

CCAR:

109050634 109051126 109061824 109061825

CAUA:

113043282 113066447 113105280

CGIB:

127947322 127961681 128014718

PTET:

122331134 122348300(rlbp1a)

LROH:

127156744(rlbp1b) 127167808(rlbp1a)

GRF:	141302005(rlbp1b) 141331384(rlbp1a) 141332247

OMC:	131534663(rlbp1b) 131543653(rlbp1a)

PPRM:

120459124(rlbp1b) 120469398(rlbp1a)

RKG:	130085350(rlbp1b) 130091272(rlbp1a)

MAMB:

125247470(rlbp1b) 125264429(rlbp1a)

CIDE:

127507217 127515613

CERY:

137015445(rlbp1b) 137030410(rlbp1a)

MASI:

127435973 127437811 127445613 127451059

TROS:

130552322(rlbp1b) 130557272(rlbp1a)

TDW:	130413794(rlbp1b) 130427501(rlbp1a)

MANU:

129427713(rlbp1a) 129433402(rlbp1b)

PDAB:

135781822(rlbp1b) 135783707(rlbp1a)

IPU:	108268561(rlbp1b) 108270706(rlbp1a)

IFU:	128611293(rlbp1b) 128613574(rlbp1a)

PHYP:

113529315 113536394(rlbp1)

SMEO:

124386202(rlbp1b) 124390857(rlbp1a)

TFD:	113635580(rlbp1b) 113652826(rlbp1a)

TVC:	132842465(rlbp1a) 132855916(rlbp1b)

CGAR:

128531425(rlbp1b) 128543122(rlbp1a)

NGRA:

132890228(rlbp1b) 132898802(rlbp1a)

TRN:	134319039(rlbp1b) 134331078(rlbp1a)

AMEX:

103021449(rlbp1b) 103033538(rlbp1a)

CMAO:

118806398(rlbp1b) 118819159(rlbp1a)

EEE:	113573938(rlbp1) 113585306

CHAR:

105908115(rlbp1a) 105913419(rlbp1b)

SPIL:

134094289(rlbp1b) 134095608(rlbp1a)

ASAD:

121682458(rlbp1a) 121724132(rlbp1b)

TRU:	101080127(rlbp1) 115251986

TFS:	130517387 130535715(rlbp1b)

TNG:	GSTEN00018095G001 GSTEN00019679G001

LCO:	104922393(rlbp1) 104930527

NCC:	104951141 104957055(rlbp1)

TBEN:

117471731(rlbp1a) 117497325(rlbp1b)

CGOB:

115003665 115009979(rlbp1)

PGEO:

117448617(rlbp1b) 117464861(rlbp1a)

GACU:

117549425 117559117(rlbp1b)

EMAC:

134862604(rlbp1a) 134883405(rlbp1b)

ELY:	117259381 117261837(rlbp1b)

EFO:	125880702 125886945(rlbp1b)

PLEP:

121947045 121950373(rlbp1b)

SLUC:

116043565(rlbp1a) 116046795(rlbp1b)

ECRA:

117948536(rlbp1b) 117949234

ESP:	116693579(rlbp1) 116704934

PFLV:

114558422 114560656(rlbp1)

GAT:	120808890(rlbp1b) 120812811 120831537(rlbp1a)

PPUG:

119196581(rlbp1b) 119224532

AFB:	129105642(rlbp1a) 129108859(rlbp1b)

CLUM:

117725158 117731838(rlbp1b)

PSWI:

130195106(rlbp1b)

CANA:

137783516 137804420(rlbp1b)

CVE:	137881251(rlbp1b) 137882177

MSAM:

119893716(rlbp1b)

SCHU:

122866794(rlbp1a) 122874615(rlbp1b)

CUD:	121512829 121514952(rlbp1b)

SPUL:

138591282(rlbp1a) 138613470(rlbp1b)

LMIX:

132959348(rlbp1a) 132972950(rlbp1b)

HTC:	141788044(rlbp1a) 141796874(rlbp1b)

ALAT:

119018001(rlbp1a) 119023783(rlbp1b)

ASTR:

137593990(rlbp1b) 137596348

MZE:	101463974(rlbp1) 101483584

ONL:	100693385 100706956(rlbp1)

OAU:	116314025(rlbp1b) 116324014

OLA:	101165475(rlbp1) 101170080

OML:	112151947(rlbp1b) 112160939

CSAI:

133444553(rlbp1b) 133459701(rlbp1a)

XMA:	102223374 102223737(rlbp1)

XCO:	114142521 114161650(rlbp1)

XHE:	116718675 116736819(rlbp1)

PRET:

103462097 103465751(rlbp1)

PFOR:

103146170 103152831(rlbp1)

PLAI:

106961169(rlbp1) 106965307

PMEI:

106924778 106927945(rlbp1)

GAF:	122834953(rlbp1b) 122841606

PPRL:

129358651(rlbp1b) 129369424(rlbp1a)

CVG:	107092194(rlbp1) 107097786

CTUL:

119777298(rlbp1b) 119799093

GMU:	124858967(rlbp1b) 124866725(rlbp1a)

NFU:	107374353 107376775 107388384(rlbp1)

KMR:	108237847(rlbp1a) 108245739(rlbp1b)

ALIM:

106512954 106529590(rlbp1)

NWH:	119415407(rlbp1b) 119430225

AOCE:

111565739(rlbp1a) 111570086(rlbp1b)

EJA:	138205779(rlbp1b) 138213388(rlbp1a)

BFRE:

138618981(rlbp1b) 138625032(rlbp1a)

MCEP:

125005278(rlbp1a) 125014848(rlbp1b)

CSEM:

103379086 103379797(rlbp1)

POV:	109624548(rlbp1) 109637299

SSEN:

122772242(rlbp1a) 122775771(rlbp1b)

SSOE:

131460056(rlbp1a) 131469633(rlbp1b)

HHIP:

117759575 117759577 117763682(rlbp1b)

HSP:	118109033(rlbp1a) 118109595(rlbp1b)

PPLT:

128444223(rlbp1b) 128447164(rlbp1a)

SMAU:

118302871 118314914(rlbp1b)

LCF:	108888036 108889287(rlbp1b)

SDU:	111229616(rlbp1) 111238661

SLAL:

111650397(rlbp1) 111661136

XGL:	120790100 120793358(rlbp1b)

HCQ:	109514409 109518267(rlbp1)

SSCV:

125967052 125970068(rlbp1b)

SBIA:

133498498(rlbp1a) 133502503

PEE:	133399168 133403196(rlbp1b)

PTAO:

133470837 133477955(rlbp1b)

BPEC:

110169234(rlbp1) 110174543

ENY:	140349487(rlbp1b) 140381018

MALB:

109963357 109974808(rlbp1)

BSPL:

114842786 114857820(rlbp1b)

SJO:	128359079(rlbp1b) 128361178

SSCO:

133982367(rlbp1b) 133993761

TTY:	137179604(rlbp1a) 137183420(rlbp1b)

GMH:	115551054(rlbp1) 115558432

SASA:

106561097 106561906 106584650

STRU:

115192845 115197110 115202829

OTW:	112221457 112232299 112233000

OMY:	110492010 110506273(rlbp1a) 110521248

OGO:	124035110(rlbp1a) 124037002 124039751

ONE:	115113448 115134541 115145429

OKI:	109866921 109895038 109897444

OKE:	118358764 118362710 118396393

OMM:	135508752 135535936 135554217(rlbp1a) 135555166

OCLA:

139368868 139384785 139407552

SALP:

111962098 111969190 111972047(rlbp1)

SNH:	120024913(rlbp1a) 120051712 120066614

SFON:

129834287 129854942 129862799

CCLU:

121532123 121540013 121580111 121583259

ELS:	105007374 105028546(rlbp1)

OEP:	134021373(rlbp1b) 134028398(rlbp1a)

SFM:	108940877 108941996

PKI:	111836484 111845063

AANG:

118215163(rlbp1b) 118227024

AROT:

135241518(rlbp1b) 135255481

CCOG:

133111071(rlbp1b) 133131488(rlbp1a)

LOC:	102682970(rlbp1)

PSPA:

121294468 121299257

ARUT:

117428001 117962442

PSEX:

120540429(rlbp1a)

LCM:	102349522(RLBP1) 102354310

CMK:	103188381(rlbp1a)

RTP:	109923209(rlbp1b)

CPLA:

122540932(rlbp1b)

SCAU:

119974203(rlbp1b)

LERI:

129712779

HAKA:

140718749(rlbp1b)

PMRN:

116940205(RLBP1)

LRJ:	133346689(RLBP1)

CIN:	100177135 100185518

GAE:

121373353

HRF:	124112567 124115431

HRJ:	124260632 124283885

HASI:

137259716 137277019

HCRA:

139460751 139466539

OBI:	106869923 106871190

OSN:	115219739 115219888

LJP:

HMG:

HSY:

RES:

Reference

PMID:22551409

Authors

Burstedt M, Jonsson F, Kohn L, Burstedt M, Kivitalo M, Golovleva I

Title

Genotype-phenotype correlations in Bothnia dystrophy caused by RLBP1 gene sequence variations.

Journal

Acta Ophthalmol 91:437-44 (2013)
DOI:10.1111/j.1755-3768.2012.02431.x

Sequence

[hsa:6017]

Reference

PMID:19458327

Authors

Farjo KM, Moiseyev G, Takahashi Y, Crouch RK, Ma JX

Title

The 11-cis-retinol dehydrogenase activity of RDH10 and its interaction with visual cycle proteins.

Journal

Invest Ophthalmol Vis Sci 50:5089-97 (2009)
DOI:10.1167/iovs.09-3797

LinkDB

DBGET integrated database retrieval system