KEGG   ORTHOLOGY: K19728
Entry
K19728                      KO                                     
Symbol
UNC13D, MUNC13
Name
protein unc-13 D
Disease
H00109  Familial hemophagocytic lymphohistiocytosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K19728  UNC13D, MUNC13; protein unc-13 D
Membrane trafficking [BR:ko04131]
 SNARE
  SNARE associated proteins
   Syntaxin-binding proteins
    K19728  UNC13D, MUNC13; protein unc-13 D
Genes
HSA: 201294(UNC13D)
PTR: 454891(UNC13D)
PPS: 100986974(UNC13D)
GGO: 101141735(UNC13D)
PON: 100458741(UNC13D)
PPYG: 129016770(UNC13D)
NLE: 100607657(UNC13D)
HMH: 116484074(UNC13D)
SSYN: 129462259(UNC13D)
MCC: 704431(UNC13D)
MCF: 102137426(UNC13D)
MTHB: 126939165
MNI: 105469178(UNC13D)
CSAB: 103243028(UNC13D)
CATY: 105577716(UNC13D)
PANU: 101009504(UNC13D)
TGE: 112609114(UNC13D)
MLEU: 105528723(UNC13D)
RRO: 104681295(UNC13D)
RBB: 108537361(UNC13D)
TFN: 117066696(UNC13D)
PTEH: 111542408(UNC13D)
CANG: 105505276(UNC13D)
CJC: 100390869(UNC13D)
SBQ: 101037068(UNC13D)
CIMI: 108309435(UNC13D)
ANAN: 105718262(UNC13D)
CSYR: 103250487(UNC13D)
MMUR: 105878948(UNC13D)
LCAT: 123650808(UNC13D)
PCOQ: 105824717(UNC13D)
OGA: 100952066(UNC13D)
MMU: 70450(Unc13d)
MCAL: 110305478(Unc13d)
MPAH: 110331891(Unc13d)
RNO: 192177(Unc13d)
MCOC: 116079108(Unc13d)
ANU: 117709981(Unc13d)
ASYL: 127694566(Unc13d)
MUN: 110547958(Unc13d)
CGE: 100757716(Unc13d)
MAUA: 101825050(Unc13d)
PROB: 127219335(Unc13d)
PLEU: 114707051(Unc13d)
MORG: 121436251(Unc13d)
MFOT: 126500516
AAMP: 119813520(Unc13d)
NGI: 103732713(Unc13d)
HGL: 101700358(Unc13d)
CPOC: 100725879(Unc13d)
CCAN: 109695992(Unc13d)
DORD: 106003248(Unc13d)
DSP: 122128348(Unc13d)
PLOP: 125365688(Unc13d)
NCAR: 124981231
MMMA: 107157768(Unc13d)
ITI: 101963543(Unc13d)
OCU: 103345793
OPI: 101523794(UNC13D)
TUP: 102485843(UNC13D)
GVR: 103585186(UNC13D)
CFA: 483319(UNC13D)
CLUD: 112672810(UNC13D)
VVP: 112920806(UNC13D)
VLG: 121472584(UNC13D)
NPO: 129512658(UNC13D)
AML: 100479835(UNC13D)
UMR: 103665942(UNC13D)
UAH: 113244621(UNC13D)
UAR: 123803253(UNC13D)
ELK: 111160308
LLV: 125087178
MPUF: 101674585(UNC13D)
MNP: 132004448(UNC13D)
MLK: 131816970(UNC13D)
NVS: 122905976(UNC13D)
ORO: 101383056(UNC13D)
EJU: 114216176(UNC13D)
ZCA: 113939245(UNC13D)
MLX: 118024258(UNC13D)
NSU: 110581921(UNC13D)
LWW: 102731123(UNC13D)
FCA: 101081343(UNC13D)
PYU: 121017926(UNC13D)
PCOO: 112864512(UNC13D)
PBG: 122485911(UNC13D)
PVIV: 125151840(UNC13D)
LRUF: 124513405
LGF: 123604019(UNC13D)
AJU: 106987749
PTG: 102963788(UNC13D)
PPAD: 109276917(UNC13D)
PUC: 125926352
PLEZ: 122207192(UNC13D)
HHV: 120228210(UNC13D)
BTA: 506146(UNC13D)
BOM: 102265560(UNC13D)
BIU: 109573671(UNC13D)
BBUB: 102399711(UNC13D)
BBIS: 105000356(UNC13D)
CHX: 102172098(UNC13D)
OAS: 101119148(UNC13D)
BTAX: 128065053(UNC13D)
CSUM: 138083109(UNC13D)
ODA: 120866727(UNC13D)
CCAD: 122436860(UNC13D)
MREE: 136149277(UNC13D)
OVR: 110152083(UNC13D)
MBEZ: 129544710(UNC13D)
SSC: 100521332(UNC13D)
CFR: 102504299(UNC13D)
CBAI: 105065802(UNC13D)
CDK: 105104666(UNC13D)
VPC: 102535874(UNC13D)
BACU: 103017379(UNC13D)
BMUS: 118887522(UNC13D)
LVE: 103075907(UNC13D)
OOR: 101284759(UNC13D)
LALB: 132510784(UNC13D)
DLE: 111182812(UNC13D)
PCAD: 102985758(UNC13D)
PSIU: 116745882(UNC13D)
NASI: 112410327(UNC13D)
ECB: 100059416(UNC13D)
EPZ: 103546594(UNC13D)
EAI: 106830307(UNC13D)
MYB: 102260091(UNC13D)
MYD: 102760538(UNC13D)
MMYO: 118672099(UNC13D)
MDT: 132219104(UNC13D)
MYUM: 138993950(UNC13D)
PKL: 118704633(UNC13D)
EFUS: 103298277(UNC13D)
MNA: 107536579(UNC13D)
DRO: 112298795(UNC13D)
SHON: 119000419(UNC13D)
AJM: 119058640(UNC13D)
PDIC: 114502749(UNC13D)
PHAS: 123816872(UNC13D)
MMF: 118634355(UNC13D)
PPAM: 129086644(UNC13D)
HAI: 109383634(UNC13D)
RFQ: 117013278(UNC13D)
PALE: 102897275(UNC13D)
PGIG: 120600016(UNC13D)
PVP: 105293364(UNC13D)
RAY: 107501507(UNC13D)
MJV: 108406164(UNC13D)
TOD: 119232325(UNC13D)
SARA: 101556915(UNC13D)
SFUM: 130045474(UNC13D)
SETR: 126004284(UNC13D)
LAV: 100671311(UNC13D)
TMU: 101352005
ETF: 101658054(UNC13D)
DNM: 101411843(UNC13D)
MDO: 100027164(UNC13D)
GAS: 123246209(UNC13D)
SHR: 100918125(UNC13D)
AFZ: 127560458
PCW: 110219379(UNC13D)
TVP: 118845464(UNC13D)
PBRV: 138152502(UNC13D)
OAA: 100077998(UNC13D)
TACU: 119922020(UNC13D)
GGA: 417369(UNC13D)
PCOC: 116232594(UNC13D)
MGP: 100541726(UNC13D)
CJO: 107322276(UNC13D)
TPAI: 128082940(UNC13D)
LMUT: 125702166(UNC13D)
NMEL: 110407461(UNC13D)
APLA: 101800021(UNC13D)
ACYG: 106034794(UNC13D)
CATA: 118253825(UNC13D)
AFUL: 116496508(UNC13D)
TGU: 100227523(UNC13D)
LSR: 110476597(UNC13D)
SCAN: 103819856(UNC13D)
PMOA: 120505685(UNC13D)
OTC: 121338311(UNC13D)
PRUF: 121363893(UNC13D)
ATRC: 139602691(UNC13D)
GFR: 102037217(UNC13D)
FAB: 101806572(UNC13D)
OMA: 130260427(UNC13D)
PHI: 102103204(UNC13D)
PMAJ: 107212413(UNC13D)
CCAE: 111937297(UNC13D)
CCW: 104694386(UNC13D)
CBRC: 103621773(UNC13D)
ACOE: 138120315(UNC13D)
ETL: 114063385(UNC13D)
ZAB: 102065727(UNC13D)
ZLE: 135455312(UNC13D)
ACHL: 103803137(UNC13D)
SVG: 106860977(UNC13D)
MMEA: 130581082(UNC13D)
HRT: 120760946(UNC13D)
SATI: 136369272(UNC13D)
CCIC: 134052199(UNC13D)
FPG: 101922570(UNC13D)
FCH: 102050137(UNC13D)
CCRI: 104169497(UNC13D)
NNT: 104412913(UNC13D)
SHAB: 115616541(UNC13D)
ACUN: 113486791(UNC13D)
TALA: 104366860(UNC13D)
ACHC: 115342241(UNC13D)
HLE: 104839179(UNC13D)
AGEN: 126043288
HHAR: 128151407(UNC13D)
GCL: 127024085
CSTI: 104552616
LDI: 104352143(UNC13D)
MNB: 103774401(UNC13D)
DPUB: 104297917(UNC13D)
PPUS: 135179710(UNC13D)
AVIT: 104280219
EGZ: 104125391(UNC13D)
NNI: 104022877(UNC13D)
PCRI: 104032544(UNC13D)
PADL: 103917476(UNC13D)
AFOR: 103899076(UNC13D)
CBOY: 140660506(UNC13D)
CLV: 102097330(UNC13D)
MUI: 104543087(UNC13D)
PGUU: 104472472(UNC13D)
EHS: 104515068(UNC13D)
CMAC: 104479164
CUCA: 104061959(UNC13D)
TEO: 104375784(UNC13D)
BREG: 104632301(UNC13D)
OHA: 104337277(UNC13D)
ACAR: 104532232
CPEA: 104393241(UNC13D)
CVF: 104295996(UNC13D)
RTD: 128917775(UNC13D)
CRID: 134523279(UNC13D)
AAM: 106483837(UNC13D)
AROW: 112977708(UNC13D)
NPD: 112953723(UNC13D)
TGT: 104572189(UNC13D)
DNE: 112982449(UNC13D)
SCAM: 104138595(UNC13D)
ASN: 102380232(UNC13D)
AMJ: 102570033(UNC13D)
CPOO: 109315085(UNC13D)
GGN: 109287990(UNC13D)
PSS: 102447721(UNC13D)
CMY: 102936855(UNC13D)
CCAY: 125621329(UNC13D)
DCC: 119843126(UNC13D)
CPIC: 101942831(UNC13D)
TST: 117887234(UNC13D)
CABI: 116832247(UNC13D)
MRV: 120383367(UNC13D)
ACS: 100555716(unc13d)
ASAO: 132768602(UNC13D)
PVT: 110085181(UNC13D)
SUND: 121923858(UNC13D)
PBI: 103054034(UNC13D)
PMUR: 107290196(UNC13D)
CTIG: 120301149(UNC13D)
TSR: 106537453(UNC13D)
PGUT: 117660496 132710981
APRI: 131189931(UNC13D)
PTEX: 113437148(UNC13D)
NSS: 113412076(UNC13D)
VKO: 123035517(UNC13D)
PMUA: 114590627(UNC13D)
PRAF: 128407503(UNC13D)
ZVI: 118079847(UNC13D)
HCG: 128346501(UNC13D)
GJA: 107113179(UNC13D)
STOW: 125428086(UNC13D)
EMC: 129326917(UNC13D)
XLA: 108701121(unc13d.L)
XTR: 100145635(unc13d)
NPR: 108791150(UNC13D)
RTEM: 120919361(UNC13D)
BBUF: 121005953(UNC13D)
BGAR: 122940383(UNC13D)
PWL: 138246026(UNC13D)
MUO: 115473357(UNC13D)
GSH: 117367373
DRE: 564076(unc13d)
SRX: 107753247 107755420
SANH: 107684114 107704240
SGH: 107561838 107597824
CCAR: 109050710 109105168(unc13d)
CAUA: 113056012 113078143 113105078 113111663
CGIB: 127969064 128025455
PTET: 122355495(unc13d)
LROH: 127173997(unc13d)
OMC: 131551598(unc13d)
PPRM: 120474722(unc13d)
RKG: 130080151(unc13d)
MAMB: 125255486(unc13d)
CIDE: 127523329
CERY: 137007311(unc13d)
MASI: 127422949 127426848
TROS: 130568902(unc13d)
TDW: 130438771(unc13d)
MANU: 129421459(unc13d)
PDAB: 135744657(unc13d)
IPU: 108274054
IFU: 128616710(unc13d)
PHYP: 113527786(unc13d)
SMEO: 124389286(unc13d)
TFD: 113651608(unc13d)
TVC: 132862644(unc13d)
CGAR: 128541764(unc13d)
NGRA: 132898597(unc13d)
TRN: 134321586(unc13d)
AMEX: 103031376(unc13d)
CMAO: 118809073(unc13d)
EEE: 113585644(unc13d)
CHAR: 105896470(unc13d)
SPIL: 134077030(unc13d)
TRU: 101073490(unc13d)
TFS: 130538430(unc13d)
TNG: GSTEN00021719G001
LCO: 104924902(unc13d)
TBEN: 117497666(unc13d)
CGOB: 115024984(unc13d)
PGEO: 117444701(unc13d)
GACU: 117533140(unc13d)
EMAC: 134870581(unc13d)
ELY: 117247390(unc13d)
EFO: 125880355(unc13d)
PLEP: 121958880(unc13d)
SLUC: 116044086(unc13d)
ECRA: 117937383(unc13d)
ESP: 116671119(unc13d)
PFLV: 114547751(unc13d)
GAT: 120819823(unc13d)
PPUG: 119212723(unc13d)
AFB: 129091048(unc13d)
CLUM: 117748783(unc13d)
PSWI: 130203127(unc13d)
CANA: 137789601(unc13d)
MSAM: 119915731(unc13d)
SCHU: 122867924(unc13d)
CUD: 121528224(unc13d)
SPUL: 138593229(unc13d)
LMIX: 132955107(unc13d)
ALAT: 119010376(unc13d)
ASTR: 137588652(unc13d)
MZE: 101466551(unc13d)
ONL: 100692043(unc13d)
OAU: 116330868(unc13d)
OLA: 101158680(unc13d)
OML: 112141352(unc13d)
CSAI: 133419325(unc13d)
XMA: 102233171(unc13d)
XCO: 114151779(unc13d)
XHE: 116726879(unc13d)
PRET: 103481947(unc13d)
PFOR: 103144119(unc13d)
PLAI: 106935300
PMEI: 106927043
GAF: 122822979(unc13d)
PPRL: 129377499(unc13d)
CVG: 107098151(unc13d)
CTUL: 119792591(unc13d)
GMU: 124875046(unc13d)
NFU: 107388304(unc13d)
KMR: 108235870(unc13d)
ALIM: 106535692
NWH: 119423779(unc13d)
AOCE: 111570555(unc13d)
EJA: 138202292(unc13d)
BFRE: 138626061(unc13d)
MCEP: 125022544(unc13d)
CSEM: 103382058(unc13d)
POV: 109627123(unc13d)
SSEN: 122759627(unc13d)
SSOE: 131448635(unc13d)
HHIP: 117753166(unc13d)
HSP: 118100257(unc13d)
PPLT: 128426586(unc13d)
SMAU: 118287425(unc13d)
LCF: 108872503
SDU: 111219535(unc13d)
SLAL: 111667086(unc13d)
XGL: 120794817(unc13d)
HCQ: 109513295(unc13d)
SSCV: 125991631(unc13d)
SBIA: 133495298(unc13d)
PEE: 133418260(unc13d)
PTAO: 133469088(unc13d)
BPEC: 110155154(unc13d)
ENY: 140368652(unc13d)
MALB: 109974901(unc13d)
BSPL: 114845294(unc13d)
SJO: 128381958(unc13d)
SSCO: 134003383(unc13d)
GMH: 115530710(unc13d)
SASA: 100194820(un13d) 106589471
STRU: 115156308 115201254
OTW: 112224347 112237613
OMY: 110491319 110498732
OGO: 124040101 124048102
ONE: 115124029 115144121
OKI: 109865331 109870336
OKE: 118357407 118363462
OMM: 135505205 135523765
OCLA: 139367920 139376643
SALP: 111968237 111977500
SNH: 120029610 120046094
CCLU: 121547408 121567580
ELS: 105023030(unc13d)
OEP: 134031182(unc13d)
SFM: 108939919(unc13d)
PKI: 111856703(unc13d)
AANG: 118220784(unc13d)
AROT: 135248520(unc13d)
CCOG: 133119189(unc13d)
LOC: 102694162(unc13d)
PSPA: 121295400(unc13d)
ARUT: 117423290(unc13d)
PSEX: 120517436(unc13d)
LCM: 102356766(UNC13D)
CMK: 103175638(unc13d)
CPLA: 122562334(unc13d)
HOC: 132827874(unc13d)
LERI: 129708337(unc13d)
PMRN: 116955075
PJA: 122254739
HAME: 121871178
PCLA: 123761317
CQD: 128691366
PTRU: 123506824
RSAN: 119391263 119395034
RMP: 119160976
CVN: 111137969
RPHI: 132744808
MAEA: 128210862 128230808 128232734
MBR: MONBRDRAFT_34784
 » show all
Reference
PMID:17237785
  Authors
Menager MM, Menasche G, Romao M, Knapnougel P, Ho CH, Garfa M, Raposo G, Feldmann J, Fischer A, de Saint Basile G
  Title
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4.
  Journal
Nat Immunol 8:257-67 (2007)
DOI:10.1038/ni1431
  Sequence
[hsa:201294]
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