KEGG ORTHOLOGY: K19751

ORTHOLOGY: K19751

Entry

K19751                      KO

Symbol

DNAAF2, KTU, PF13

Name

dynein axonemal assembly factor 2

Disease

H00564

Primary ciliary dyskinesia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K19751  DNAAF2, KTU, PF13; dynein axonemal assembly factor 2
   04812 Cytoskeleton proteins
    K19751  DNAAF2, KTU, PF13; dynein axonemal assembly factor 2
Cilium and associated proteins [BR:ko03037]
Motile cilia and associated proteins
  Dynein assembly factors
   K19751  DNAAF2, KTU, PF13; dynein axonemal assembly factor 2
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     Dynein-related proteins
      K19751  DNAAF2, KTU, PF13; dynein axonemal assembly factor 2

Genes

HSA:	55172(DNAAF2)

PTR:	452887(DNAAF2)

PPS:	100990825(DNAAF2)

GGO:	101136092(DNAAF2)

PON:	100460194(DNAAF2)

PPYG:

129012569(DNAAF2)

NLE:	100606671(DNAAF2)

HMH:	116456183(DNAAF2)

SSYN:

129487934(DNAAF2)

MCC:	719026(DNAAF2)

MCF:	102129823(DNAAF2)

MTHB:

126958503

MNI:	105481861(DNAAF2)

CSAB:

103228940(DNAAF2)

CATY:

105586583(DNAAF2)

PANU:

101027043(DNAAF2)

TGE:	112628591(DNAAF2)

MLEU:

105554522(DNAAF2)

RRO:	104682760(DNAAF2)

RBB:	108513659(DNAAF2)

TFN:	117069684(DNAAF2)

PTEH:

111549516(DNAAF2)

CANG:

105522401(DNAAF2)

CJC:	100403583(DNAAF2)

SBQ:	101051506(DNAAF2)

CIMI:

108287963(DNAAF2)

ANAN:

105719943(DNAAF2)

MMUR:

105867649(DNAAF2)

LCAT:

123649577(DNAAF2)

PCOQ:

105825898(DNAAF2)

OGA:	100945474(DNAAF2)

MMU:	109065(Dnaaf2)

MCAL:

110306693(Dnaaf2)

MPAH:

110324279(Dnaaf2)

RNO:	362746(Dnaaf2)

MCOC:

116079776(Dnaaf2)

ANU:	117716806(Dnaaf2)

ASYL:

127687287(Dnaaf2)

MUN:	110556908(Dnaaf2)

CGE:	100753981(Dnaaf2)

MAUA:

101840920(Dnaaf2)

PROB:

127230636(Dnaaf2)

PLEU:

114684314(Dnaaf2)

MORG:

121452103(Dnaaf2)

MFOT:

126508423

AAMP:

119818613(Dnaaf2)

NGI:	103731524(Dnaaf2)

HGL:	101704134(Dnaaf2)

CPOC:

100724856(Dnaaf2)

CCAN:

109693255(Dnaaf2)

DORD:

105982577(Dnaaf2)

DSP:	122106497(Dnaaf2)

PLOP:

125363203(Dnaaf2)

NCAR:

124976242

MMMA:

107146795(Dnaaf2)

ITI:	101975797(Dnaaf2)

OCU:

100348925

OPI:	101524237(DNAAF2)

TUP:	102476689(DNAAF2)

GVR:	103586056(DNAAF2)

CFA:	480313(DNAAF2)

CLUD:

112657313(DNAAF2)

VVP:	112921460(DNAAF2)

VLG:	121493137(DNAAF2)

NPO:	129496108(DNAAF2)

AML:	100473128(DNAAF2)

UMR:	103666297(DNAAF2)

UAH:	113266189(DNAAF2)

UAR:	123793351(DNAAF2)

ELK:

111160129

LLV:

125103712

MPUF:

101671563(DNAAF2)

MNP:	131999919(DNAAF2)

MLK:	131836521(DNAAF2)

NVS:	122894089(DNAAF2)

ORO:	101382349(DNAAF2)

EJU:	114211430(DNAAF2)

ZCA:	113908674(DNAAF2)

MLX:	118002590(DNAAF2)

NSU:	110590644(DNAAF2)

LWW:	102745619(DNAAF2)

FCA:	101092369(DNAAF2)

PYU:	121031722(DNAAF2)

PCOO:

112856269(DNAAF2)

PBG:	122469055(DNAAF2)

PVIV:

125167341(DNAAF2)

LRUF:

124512222

LGF:	123583788(DNAAF2)

AJU:

106985091

PTG:	102949570(DNAAF2)

PPAD:

109268515(DNAAF2)

PUC:

125909527

PLEZ:

122222524(DNAAF2)

HHV:	120220268(DNAAF2)

BTA:	534465(DNAAF2)

BOM:	102280485(DNAAF2)

BIU:	109565007(DNAAF2)

BBUB:

102409534(DNAAF2)

BBIS:

104990276(DNAAF2)

CHX:	102189042(DNAAF2)

OAS:	101122790(DNAAF2)

BTAX:

128054470(DNAAF2)

CSUM:

138072797(DNAAF2)

ODA:	120853128(DNAAF2)

CCAD:

122443451(DNAAF2)

MREE:

136172361(DNAAF2)

OVR:	110148540(DNAAF2)

MBEZ:

129562394(DNAAF2)

SSC:	100521173(DNAAF2)

CFR:	102521371(DNAAF2)

CBAI:

105078496(DNAAF2)

CDK:	105091462(DNAAF2)

VPC:	102534561(DNAAF2)

BACU:

103017794(DNAAF2)

BMUS:

118889988(DNAAF2)

LVE:	103083800(DNAAF2)

OOR:	101282144(DNAAF2)

LALB:

132516599(DNAAF2)

DLE:	111173186(DNAAF2)

PCAD:

102976206(DNAAF2)

PSIU:

116749042(DNAAF2)

NASI:

112391505(DNAAF2)

ECB:	100065764(DNAAF2)

EPZ:	103556134(DNAAF2)

EAI:	106839520(DNAAF2)

MYB:	102250841(DNAAF2)

MYD:	102755244(DNAAF2)

MMYO:

118674969(DNAAF2)

MLF:	102442761(DNAAF2)

MDT:	132212864(DNAAF2)

MYUM:

139021191(DNAAF2)

PKL:	118730019(DNAAF2)

EFUS:

103294943(DNAAF2)

MNA:	107537517(DNAAF2)

DRO:	112301787(DNAAF2)

SHON:

118987804(DNAAF2)

AJM:	119036785(DNAAF2)

PDIC:

114492039(DNAAF2)

PHAS:

123825308(DNAAF2)

MMF:	118625327(DNAAF2)

PPAM:

129086501(DNAAF2)

HAI:	109393289(DNAAF2)

RFQ:	117023929(DNAAF2)

PALE:

102884194(DNAAF2)

PGIG:

120597933(DNAAF2)

PVP:	105302782(DNAAF2)

RAY:	107518855(DNAAF2)

MJV:	108406355(DNAAF2)

TOD:	119239062(DNAAF2)

SARA:

101554092(DNAAF2)

SFUM:

130041569(DNAAF2)

SETR:

125999146(DNAAF2)

LAV:	100671454(DNAAF2)

TMU:

101345511

ETF:	101642930(DNAAF2)

DNM:	101429156(DNAAF2)

MDO:	100028942(DNAAF2)

GAS:	123237708(DNAAF2)

SHR:	111720663(DNAAF2)

AFZ:

127549670

PCW:	110220678(DNAAF2)

TVP:	118828202(DNAAF2)

PBRV:

138164288(DNAAF2)

OAA:	100084512(DNAAF2)

TACU:

119936762(DNAAF2)

GGA:	423566(DNAAF2)

PCOC:

116234578(DNAAF2)

MGP:	109367989(DNAAF2)

CJO:	107315494(DNAAF2)

TPAI:

128087197(DNAAF2)

LMUT:

125695078(DNAAF2)

NMEL:

110401147(DNAAF2)

APLA:

101801844(DNAAF2)

ACYG:

106046973(DNAAF2)

CATA:

118250260(DNAAF2)

AFUL:

116489954(DNAAF2)

TGU:	100227690(DNAAF2)

LSR:	110473488(DNAAF2)

PMOA:

120497070(DNAAF2)

OTC:	121339044(DNAAF2)

PRUF:

121348722(DNAAF2)

ATRC:

139589591(DNAAF2)

FAB:	101816957(DNAAF2)

OMA:	130253541(DNAAF2)

PHI:	102104353(DNAAF2)

PMAJ:

107206211(DNAAF2)

CCAE:

111929513(DNAAF2)

CCW:	104695921(DNAAF2)

CBRC:

108447817(DNAAF2)

ACOE:

138112025(DNAAF2)

ETL:	114069221(DNAAF2)

ZAB:

106630085

ZLE:	135449248(DNAAF2)

SVG:	106858938(DNAAF2)

MMEA:

130583792(DNAAF2)

HRT:	120754000(DNAAF2)

SATI:

136362696(DNAAF2)

CCIC:

134045475(DNAAF2)

FPG:	101913753(DNAAF2)

FCH:	102060145(DNAAF2)

SHAB:

115606692(DNAAF2)

ACUN:

113480381(DNAAF2)

TALA:

116964199(DNAAF2)

ACHC:

115352610(DNAAF2)

HALD:

104313708(DNAAF2)

HLE:	104839517(DNAAF2)

AGEN:

126050729

HHAR:

128140157(DNAAF2)

GCL:

127016847

LDI:	104342293(DNAAF2)

PPUS:

135175016(DNAAF2)

NNI:	104019495(DNAAF2)

PADL:

103914915(DNAAF2)

AFOR:

103907694(DNAAF2)

CBOY:

140653680(DNAAF2)

CLV:	110360683(DNAAF2)

PLET:

104625193(DNAAF2)

BREG:

104641027(DNAAF2)

CVF:	104294334(DNAAF2)

RTD:	128908992(DNAAF2)

CRID:

134515137(DNAAF2)

AAM:	106487023(DNAAF2)

AROW:

112961215(DNAAF2)

NPD:	112957765(DNAAF2)

DNE:	112993840(DNAAF2)

AMJ:	102561866(DNAAF2)

CPOO:

109320902(DNAAF2)

GGN:	109299269(DNAAF2)

CMY:	102939741(DNAAF2)

CCAY:

125639197(DNAAF2)

DCC:	119857728(DNAAF2)

CPIC:

101938214(DNAAF2)

TST:	117876355(DNAAF2)

CABI:

116818093(DNAAF2)

MRV:	120403643(DNAAF2)

ACS:	100553603(dnaaf2)

ASAO:

132762166 132762167

PVT:	110070670(DNAAF2)

SUND:

121924002(DNAAF2)

PBI:	103052247(DNAAF2)

PMUR:

107298226(DNAAF2)

CTIG:

120301823(DNAAF2)

TSR:	106545944 106545952

PGUT:

117675036(DNAAF2)

APRI:

131188117(DNAAF2)

PTEX:

113435155(DNAAF2)

NSS:	113414140(DNAAF2)

VKO:	123026537(DNAAF2)

PMUA:

114585440(DNAAF2)

PRAF:

128411454(DNAAF2)

ZVI:	118097729(DNAAF2)

HCG:	128332195(DNAAF2)

GJA:	107122498(DNAAF2)

STOW:

125427098(DNAAF2)

EMC:	129324416(DNAAF2)

XLA:	100158322(dnaaf2.L)

XTR:	779929(dnaaf2)

NPR:	108786859(DNAAF2)

RTEM:

120920219(DNAAF2)

BBUF:

120982329(DNAAF2)

BGAR:

122921976(DNAAF2)

PWL:	138260319(DNAAF2)

MUO:	115478002(DNAAF2)

GSH:	117363905(DNAAF2)

DRE:	606664(dnaaf2)

SRX:	107748246(dnaaf2)

SANH:

107660575(dnaaf2)

SGH:	107573110(dnaaf2)

CCAR:

109093244(dnaaf2)

CAUA:

113074529 113098453

CGIB:

127933164

PTET:

122334456(dnaaf2)

LROH:

127179386(dnaaf2)

OMC:	131523538(dnaaf2)

PPRM:

120477706(dnaaf2)

RKG:	130071824(dnaaf2)

MAMB:

125269192(dnaaf2)

CIDE:

127498504

CERY:

137006571(dnaaf2)

MASI:

127455263

TROS:

130559984(dnaaf2)

TDW:	130436594(dnaaf2)

PDAB:

135761024(dnaaf2)

IPU:

108269534

IFU:	128612662(dnaaf2)

PHYP:

113529711(dnaaf2)

SMEO:

124390581(dnaaf2)

TFD:	113651182(dnaaf2)

TVC:	132852272(dnaaf2)

CGAR:

128536123(dnaaf2)

NGRA:

132893834(dnaaf2)

TRN:	134325572(dnaaf2)

AMEX:

103039148(dnaaf2)

CMAO:

118823736(dnaaf2)

EEE:	113587275(dnaaf2)

CHAR:

105899573(dnaaf2)

SPIL:

134067174(dnaaf2)

TRU:	101063047(dnaaf2)

TFS:	130539953(dnaaf2)

TNG:	GSTEN00032189G001

LCO:	104922131(dnaaf2)

NCC:	104953599(dnaaf2)

TBEN:

117477595(dnaaf2)

CGOB:

115027810

PGEO:

117467862(dnaaf2)

GACU:

117550126(dnaaf2)

EMAC:

134881775(dnaaf2)

ELY:	117267451(dnaaf2)

EFO:	125900369(dnaaf2)

PLEP:

121953984(dnaaf2)

SLUC:

116035749(dnaaf2)

ECRA:

117935923(dnaaf2)

ESP:	116670263(dnaaf2)

PFLV:

114547033(dnaaf2)

GAT:	120832484(dnaaf2)

PPUG:

119227940

AFB:	129103789(dnaaf2)

CLUM:

117751369(dnaaf2)

PSWI:

130191619 130201941

CANA:

137787929

CVE:

137884590

MSAM:

119910501(dnaaf2)

SCHU:

122861554(dnaaf2)

CUD:

121526572

SPUL:

138591217

LMIX:

132993131

ALAT:

119034417(dnaaf2)

ASTR:

137611171(dnaaf2)

MZE:	101472379(dnaaf2)

ONL:	100699856(dnaaf2)

OAU:	116334752(dnaaf2)

OLA:	100192402(dnaaf2)

OML:	112148627(dnaaf2)

CSAI:

133462143(dnaaf2)

XMA:	102216885(dnaaf2)

XCO:	114134279(dnaaf2)

XHE:	116709413(dnaaf2)

PRET:

103458868(dnaaf2)

PFOR:

103144276(dnaaf2)

PLAI:

106954178(dnaaf2)

PMEI:

106926875(dnaaf2)

GAF:	122845600(dnaaf2)

PPRL:

129374731(dnaaf2)

CVG:	107087564(dnaaf2)

CTUL:

119784280(dnaaf2)

GMU:	124885032(dnaaf2)

NFU:	107392276(dnaaf2)

KMR:	108233796(dnaaf2)

ALIM:

106521701(dnaaf2)

NWH:

119427704

AOCE:

111565942 129347823

EJA:	138199969(dnaaf2)

BFRE:

138632532(dnaaf2)

MCEP:

125024093(dnaaf2)

CSEM:

103377617(dnaaf2)

POV:	109645483(dnaaf2)

SSEN:

122783030(dnaaf2)

SSOE:

131444708(dnaaf2)

HHIP:

117755836(dnaaf2)

HSP:	118116957(dnaaf2)

PPLT:

128451425(dnaaf2)

SMAU:

118285691(dnaaf2)

LCF:

108888128

SDU:	111226185(dnaaf2)

SLAL:

111644732(dnaaf2)

XGL:	120795675(dnaaf2)

HCQ:	109526120(dnaaf2)

SSCV:

125980384(dnaaf2)

SBIA:

133513729(dnaaf2)

PEE:	133413072(dnaaf2)

PTAO:

133487481(dnaaf2)

BPEC:

110155415(dnaaf2)

ENY:	140348984 140370323

MALB:

109955098(dnaaf2)

BSPL:

114848263(dnaaf2)

SJO:

128374929

SSCO:

134001310(dnaaf2)

GMH:	115543961(dnaaf2)

STRU:

115172908(dnaaf2)

OMY:	110498190(dnaaf2)

OGO:	124001815(dnaaf2)

ONE:	115146523(dnaaf2)

OKI:	109894699(dnaaf2)

OKE:	118362126(dnaaf2)

OMM:	135508469(dnaaf2)

OCLA:

139375405

SALP:

111968398(dnaaf2)

SNH:

120059716

CCLU:

121539025(dnaaf2)

ELS:	105015982(dnaaf2)

OEP:	134026555(dnaaf2)

SFM:	108941452(dnaaf2)

PKI:	111852432(dnaaf2)

AANG:

118231361(dnaaf2)

AROT:

135251938(dnaaf2)

CCOG:

133106616(dnaaf2)

LOC:	102695394(dnaaf2)

PSPA:

121330053(dnaaf2)

ARUT:

117418583 117422198

PSEX:

120519018(dnaaf2)

LCM:	102353462(DNAAF2)

CMK:	103175352(dnaaf2)

RTP:	109932781(dnaaf2)

CPLA:

122553502

HOC:	132817953(dnaaf2)

LERI:

129700535(dnaaf2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG1553(Nop17l)

DER:

6541773

DSE:

6608060

DSI:	Dsimw501_GD15300(Dsim_GD15300)

DYA:	Dyak_GE23618

DAN:

DSR:

DPO:

DPE:

DMN:	108159461 117189837

DWI:

26529739

DGR:

6559093

DMO:	Dmoj_GI19552

DAZ:

108615541

DNV:

108653936

DHE:

111593818

DVI:	6625677(Nop17l)

CCAT:

101461734

BOD:

106621307

BDR:

105222895

RZE:	108370162 108370164 108377560

AOQ:

129243983

ALUD:

128868639

TDA:

119683594

MDE:	101896448 131803811

SCAC:

106086677

LCQ:

111676968

LSQ:

119602471

CVJ:	135961092(Nop17l)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ018720

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139103350(Nop17l)

TLN:	139816803(Nop17l)

HST:

DQU:

CFO:

FEX:

PMEC:

138939832(Nop17l)

LHU:	105667528(Nop17l)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124211829(Nop17l)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138127127(Nop17l)

DPA:

109535204

ESIM:

136408160(Nop17l)

EFOR:

136342779(Nop17l)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213010

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137930226(Nop17l)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

NLU:	111043227 120353192

MQU:	128989760 128990582

PHU:	Phum_PHUM174790

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138693110(Nop17l)

SGRE:

BROR:

IEL:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

MNZ:

MRJ:	136849074(Nop17l)

PORN:

139765101(Nop17l)

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

CSCU:

CVS:	136974604(Nop17l)

PTEP:

107451751

LPOL:

106469428

HRO:	HELRODRAFT_64915

LGI:	LOTGIDRAFT_123979

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115212890 115229780

LJP:

135466453

LAK:

106153809

SMM:	Smp_077120

OVI:	T265_13794

EGL:

LLON:

NVE:

EPA:

ATEN:

MCAZ:

MFOO:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_58275

AQU:

105316789

SMO:	SELMODRAFT_406682 SELMODRAFT_417083

PPP:

112294380

CRE:	CHLRE_09g411450v5

VCN:	VOLCADRAFT_118968

MIS:	MICPUN_50263

MPP:	MICPUCDRAFT_62486

MBR:	MONBRDRAFT_22571

SRE:	PTSG_00851

TET:	TTHERM_00145250

PTM:	GSPATT00018386001

TPS:	THAPSDRAFT_1057

AAF:	AURANDRAFT_71976

PIF:	PITG_12873

PSOJ:

PHYSODRAFT_511746

SPAR:

SPRG_11517

TBR:	Tb10.389.0670

TBG:	TbgDal_X15510

TCR:	503939.40 509805.170

LMA:	LMJF_18_1240

LIF:	LINJ_18_1250

LDO:	LDBPK_181250

LMI:	LMXM_18_1240

LMAT:

92516689(LSCM1_06770)

LBZ:	LBRM_18_1330

LPAN:

LPMP_181240

LOI:	92362964(LSCM4_07126)

LEIS:

94182405(GH5_07142)

LENR:

94174245(CUR178_07086)

LEIN:

94189542(JIQ42_05923)

PHET:

94292634(JKF63_06608)

NGR:	NAEGRDRAFT_80717

» show all

Reference

PMID:19052621

Authors

Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges NT, Hagiwara H, Zhang Q, Leblond G, O'Toole E, Hara C, Mizuno H, Kawano H, Fliegauf M, Yagi T, Koshida S, Miyawaki A, Zentgraf H, Seithe H, Reinhardt R, Watanabe Y, Kamiya R, Mitchell DR, Takeda H

Title

Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

Journal

Nature 456:611-6 (2008)
DOI:10.1038/nature07471

Sequence

[hsa:55172]

LinkDB

DBGET integrated database retrieval system