| Entry |
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| Symbol |
ncsB
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| Name |
neocarzinostatin naphthoate synthase [EC: 2.3.1.237]
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| Pathway |
| map01059 | Biosynthesis of enediyne antibiotics |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00830 | Neocarzinostatin naphthoate moiety biosynthesis, malonyl-CoA => 2-hydroxy-5-methyl-1-naphthoate => 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA |
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| Reaction |
| R11125 | malonyl-CoA:acetyl-CoA malonyltransferase (2-hydroxy-5-methyl-1-naphthoic acid forming) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
K20422 ncsB; neocarzinostatin naphthoate synthase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K20422 ncsB; neocarzinostatin naphthoate synthase
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.237 neocarzinostatin naphthoate synthase
K20422 ncsB; neocarzinostatin naphthoate synthase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide synthase (PKS)
Iterative type I PKS
Bacterial type
K20422 ncsB; neocarzinostatin naphthoate synthase
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Hang VT, Oh TJ, Yamaguchi T, Sohng JK |
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| Title |
In vivo characterization of NcsB3 to establish the complete biosynthesis of the naphthoic acid moiety of the neocarzinostatin chromophore. |
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| Journal |
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| Sequence |
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| LinkDB |
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