Micromonospora sp. SH-82: WHN02_17195
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Entry
WHN02_17195 CDS
T11153
Name
(GenBank) beta-ketoacyl synthase N-terminal-like domain-containing protein
KO
K20422
neocarzinostatin naphthoate synthase [EC:
2.3.1.237
]
Organism
micn Micromonospora sp. SH-82
Pathway
micn01059
Biosynthesis of enediyne antibiotics
micn01100
Metabolic pathways
micn01110
Biosynthesis of secondary metabolites
Module
micn_M00830
Neocarzinostatin naphthoate moiety biosynthesis, malonyl-CoA => 2-hydroxy-5-methyl-1-naphthoate => 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
Brite
KEGG Orthology (KO) [BR:
micn00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
WHN02_17195
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
micn01008
]
WHN02_17195
Enzymes [BR:
micn01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.237 neocarzinostatin naphthoate synthase
WHN02_17195
Polyketide biosynthesis proteins [BR:
micn01008
]
Polyketide synthase (PKS)
Iterative type I PKS
Bacterial type
WHN02_17195
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
KAsynt_C_assoc
PP-binding
RhiE-like_linker
CurL-like_PKS_C
PS-DH
PKS_DH_N
Thiolase_N
adh_short
ACP_syn_III
DUF7080
Motif
Other DBs
NCBI-ProteinID:
XXG05950
LinkDB
All DBs
Position
3876590..3881824
Genome browser
AA seq
1744 aa
AA seq
DB search
MSCRFAPDLDSPEKFWDFLVNGRSAVGDMPEKRWKSYATSSPQATAVLRDTTLRGSFLDD
IEGFDAEFFGISPREAEFLDPQQRFMLELSWEALADAGVPPLSLRGSDTGVYVAANSNDY
GRRLLEDIPRTGAYAVNGTTFYGIANRVSYFLDLRGPSMAVDTACAGSLTALHLAAQALR
TGETPVAIVGGVNIMATPALNVALQGAGAMSPDGRSKAFDRDADGYGRGEGAGVVVLKRL
ADARRDGNPVLAVILGSIVSQDGRSDGMMAPNAQAQAQMLRQAYDRAGVDPTTVSYVEAH
GTGTPTGDGKEIEALVEVFGAGREPGDVCLIGSVKPNVGHVEGGSGITGLIKTVLAMQRG
ELPPSLHTEPTGHVDWSTCGLRLVDTRTSWTSGGRVRRAGISSYGVGGTIAHLIVQESPD
PAPVQTVPTVPTPAVYPLSAMSEAGLRGVAGATADWLDAHPDADLRSVAHTLAVRRSHLS
QRGAVVADSADQLRRRLRVLAEGRSAAGVVTDRCAPGQSTGVVWVFSGHGAQWSGMGRQL
LVGDRVFAGAVDGLAEVFRAELGWTPREALEAGGPWSATHVQALTFAVQVGLSASWCSRG
LEPGAVIGHSVGEIAAAVAAGVLDVTEAARFACRRAAALDRVSGRGAMAMVALPFAEVRE
RLVGITGVEAAISAAPRSTVVSGDRDAVTELTATWREAGLDVRTVDTDIAFHSLHVDEVL
AEVEAAARALTPRAPIVPLYSSALPDARSDSPRDHTYWTTNLRQPVRFAEAVEAAVEDGH
RLFLEVSSHPVVAHSIKECLRHRDVEDAAVVGSLRRGGEEVATLLGGLAVLHCHGAAVDW
GRAHGTGELLPLPATAWQHRPYWIFPTDGVESGPGGGHDPQQHSLLGGRMTVSGTPNRQV
WQTYLDMNTRPYPQSHGLVGVEVTPAASIINTFMAAAGREQPPALTDIVLRTPLAVVPPR
VVQIVREDRLLSLATRVPSESGGDDGDEWITHTTATIDPTAAVPSGHVDREAVRNRTEPG
SLRRIDEMFRRMGVEGYAFPWDLEELRRNDDEQLAVLTVEPSAEYAGSWAHVIDAALTIS
AAVVSPGDATVLWMSRSIDRVAHRGEPPARVVVHSRRSPRSPGDTVDVVVAGLDGRVVCE
VTGLRFAAVEHLGTAVLPRDLVHEVVWRPLPSETADRDAARPRQVVLVGDPDVGAVLAAR
FTASGVRCVHVPTGQGDDGWAPDLPAAAFTEPGVVLVLPPPVHPGGQVLEVTERAAWTLI
RTVQQLVDLDGSAPEGFAAQRLWCLTRGVRDAVEESSLAYAPLWGLGRIVAGEHPQLWGG
LVDVTDVTPDVADRLLWLTGVVAGSEDVISLADDEVRVARLAPVERSADGRPLQCSPSGT
VLITGGLGALGLEVARWLVDRGARRILLAGRRGLPPRTEWDGVGDPQVRRQIDAVLSLEA
LGVTVTVVALDITDAERAAEVLTSGSLGLPPITGIVHAAGVVNDDLVDKVDLAGLREVLA
PKAAGALVLHRLFPPGSLDFFVMFSSCGQFARLSGQASYAAANSFLDTLAAHRNAGGQTG
TVSLGWTAWRGLGLSENLTTTMTEANSRGLEAVSVSEAFRAWSFADRFQADYQAILRVLP
TPPNLPRVPMLRELVPPAADAGAAAGDGVTFDLADLDEATGRDRITADVREQVGAELNLD
AADVELKRPLVELGVDSVMTVALRVRLLRRYGLDLPPTILWAKPTVAALAGHVYEALSPT
PERG
NT seq
5235 nt
NT seq
+upstream
nt +downstream
nt
atgagctgcagattcgccccggacctcgactcgccggagaagttctgggatttcctggtg
aacgggcgcagcgccgtcggtgacatgccggagaagcggtggaagtcgtacgccacgagt
agtccccaggcgacggcggtcctgcgggacaccacattgcgtggctcctttctcgacgac
atcgaaggattcgacgcagagttcttcggcatctcaccgcgtgaggccgagtttctcgac
ccgcagcagcggttcatgctcgagctgtcgtgggaggcgctcgccgacgccggggtgcca
ccgctgtcgttgcggggcagcgacaccggcgtgtacgtcgccgccaactccaacgactac
gggcgccgcctgctcgaggacatcccgcgcaccggcgcgtacgcggtcaacggcacgacc
ttctacggcatcgccaaccgggtgtcgtacttcctggacctgcggggccccagcatggcg
gtggacaccgcctgcgccgggtcactgacggcgctgcacctggcggcccaggcactgcgt
accggggagactccggtggccatcgtcggcggggtgaacatcatggccacgcccgccctg
aacgtggcgctgcagggtgccggtgcgatgtcgcccgacggccgcagcaaggccttcgac
cgtgacgcggacggctacggccggggtgagggcgcgggcgtggtggtgctcaagcggctc
gccgacgcccgccgcgacggcaacccggtgctggcggtcatcctgggcagcatcgtctcg
caggacggacgctccgacgggatgatggcacccaatgcgcaggcacaggcgcagatgctg
cgtcaggcctacgaccgcgccggagtggacccgaccacggtgagctacgtggaggcgcac
ggcaccggcaccccgaccggtgacggcaaggagatcgaggctctcgtcgaggtcttcgga
gcgggccgggagccgggggacgtgtgcctgatcggttcggtgaaacccaacgtcggccac
gtggagggcggctccggcatcaccggcctgatcaagacggtgctggccatgcagcgggga
gagctgccccccagcctgcacaccgagcccaccgggcacgtggactggtccacctgcggg
ttgcgactggtcgacacccgtacctcctggacctccggcggtcgggtgcgccgcgccggg
atctccagctacggcgtcggcggcaccatcgcccacctgatcgtgcaggagagccccgac
ccggcgccggtgcagaccgtcccgaccgtcccgacccctgcggtgtaccccctctccgcc
atgtccgaggccggtctgcgcggggtggccggggcgaccgcggactggctggacgcccac
ccggacgccgacctgcggtcggtagcgcacaccctggcggtacgccgctcgcacctgtcg
cagcgcggcgcggtggtcgccgactccgccgaccagctgcgacgacgactccgtgtcctc
gccgaggggcgctccgccgccggggtggtgacggatcggtgcgcgcccggacagtccacc
ggggtggtctgggtcttctcggggcacggcgctcagtggtccggcatgggccggcagttg
ctggtcggtgaccgggtgttcgccggtgccgtcgacggactcgccgaggtgttccgggcc
gagctgggctggaccccgcgcgaggcgttggaggccggcggcccgtggagcgccacccac
gtgcaggccctgaccttcgccgtgcaggtcggcctcagcgcgagctggtgcagcaggggt
ctggaaccgggtgcggtgatcgggcactcggtcggtgagatcgccgccgcggtggccgcc
ggggtgctggacgtcacggaggcggcccgtttcgcctgtcggcgggcggcggcgctcgac
cgggtctccgggcgtggcgcgatggccatggtcgctctgcccttcgccgaggtccgtgag
cggctggtcgggatcaccggggtggaggcggcgatctcggccgctccccgttcgactgtc
gtctccggcgaccgggacgcggtgaccgagctgaccgccacctggcgcgaggccgggttg
gacgtccgcaccgtggacaccgacatcgccttccacagcctgcacgtcgacgaggtgctc
gccgaggtcgaggcggcggcacgggcactgacgccacgcgccccgatcgtgccgttgtac
agcagcgcactacccgacgcacgctccgacagccctcgtgaccacacctactggacgacc
aacctgcgccaaccggtgcgtttcgccgaggcggtcgaggcggccgtcgaggacgggcac
cggctgttcctggaggtctcctcgcacccggtggtggcccactcgatcaaggagtgtcta
cggcaccgtgacgtcgaggacgctgcggtcgtcggcagcctgcgccgaggcggcgaggag
gtggccacgctgctgggcgggttggcggtgctgcactgtcacggcgccgccgtggactgg
ggccgggcccacggtacgggcgaactgctgccgttgccggcgacggcgtggcagcaccgg
ccgtactggatcttcccgacggacggcgtcgaatccggtccgggcggcggccacgacccg
cagcagcacagtcttctcggcggccggatgacggtcagcggcacccccaacaggcaggtc
tggcagacctacctcgacatgaacacccggccgtatccgcagagccacggcctggtcggg
gtggaggtcaccccggcggcgtcgatcatcaacaccttcatggcggcggccgggcgggaa
cagccgccggcgttgaccgacatcgtcctgcgcaccccgctggctgtggtgccgccgcga
gtcgtgcagatcgtgcgggaggaccggctgttgtcgctggccacccgggtgcccagcgag
tccggaggcgacgacggcgacgagtggatcacccacacgacggcgacgatcgaccccacc
gccgcggtgccgtccgggcacgtcgaccgcgaggcggtgcgcaaccgtaccgagccgggg
tcgctgcgccgtatcgacgagatgttccggcggatgggtgtggagggctatgccttcccg
tgggacctggaggagttgcgtcgcaacgacgacgagcaactcgccgtcctgaccgtcgaa
ccgtccgccgagtacgccggcagttgggcgcacgtcatcgacgctgccctgacgatcagc
gccgcggtggtctccccgggcgacgccacggtgctgtggatgtcccgttcgatcgaccgg
gtggcacaccggggtgagccgccggcccgtgtcgtggtgcacagccgacgttcgccgcgt
tcccccggggacaccgtcgacgtggtggtggcaggcctcgacggcagggtcgtctgtgag
gtcaccgggctcaggttcgcggcggtggaacacctcggcacggccgtcctgccacgggac
ctggtgcacgaggtcgtctggcggccgctgccgtccgagaccgccgaccgggacgcggcg
cgaccccggcaggtcgtgctcgtcggagacccggacgtcggcgcggtcctcgccgcccgg
ttcaccgcgtcgggggtgcgctgcgtacacgtcccgaccgggcagggcgacgacgggtgg
gccccggacctgcccgcggcggcgttcaccgagcccggagtggtcctcgttctgccgccc
ccggtccaccccggcgggcaggtgctggaggtgaccgagcgggcggcgtggaccctgatc
cgtaccgtgcagcaactggtcgacctcgacggcagcgcccccgagggtttcgccgcccag
cggctgtggtgcctgacccgtggggtgcgcgacgccgtcgaggagtcctcgctggcgtac
gcgccgctgtggggcctgggccgcatcgtcgccggcgagcacccgcaactgtggggcggg
ctggtcgacgtcaccgacgtgacccccgacgtcgccgaccggctgctgtggctgacgggg
gtcgtggccggcagtgaggacgtcatctccctcgccgacgacgaggttcgggtggcccgg
ttggccccggtcgaacgcagcgccgacggaaggccgttgcagtgttcaccgtcgggaacg
gtgctgatcaccggagggctcggtgccctgggcctggaggtggcccggtggctggtcgac
cggggcgcccggcggatcctgctcgccggacggcgggggctgccgccgcgtacggagtgg
gacggggtcggcgacccgcaggtgcgccgacagatcgacgcggtgttgtcgctggaggcc
ctcggggtgacggtgacggtcgtcgccctcgacatcaccgacgccgagcgggccgccgag
gtcctcacctcgggttccctgggcctgccaccgatcaccggcatcgtccacgccgccggg
gtggtcaacgacgacctcgtcgacaaggtggacctggcggggctgcgcgaggtcctggcg
cccaaggccgccggggcgctggtgctgcaccgtctctttccgcccggcagcctggacttc
ttcgtgatgttctcctcctgtggccagttcgcccggttgtccgggcaggccagctacgcg
gcggcgaactcgttcctcgacacgctggccgcccaccgcaacgccggtgggcagaccggc
acggtcagcctggggtggacggcctggcgcgggctgggcctgtcggagaacctcaccacc
accatgaccgaggcgaactcgcggggcctggaggcggtgtcggtgtcggaggcgttccgc
gcctggtcgttcgccgaccggttccaggccgactaccaggcgatcctgcgggttctgccg
acgccgccgaaccttccgcgggtgccgatgctgcgggagttggtcccgcctgccgccgac
gcgggcgcggcggccggcgacggcgtcaccttcgacctggccgacctggacgaggcgacc
ggccgggaccggatcaccgcggacgtccgggagcaggtcggtgccgaactcaacctggac
gccgcggacgtcgagctgaagcggccgttggtcgaactcggcgtcgactcggtgatgacc
gtcgcgctgcgggtcaggctgctccgccggtacgggctggacctgccgccgacgatcctg
tgggccaaacccactgtcgccgccctggccgggcacgtctacgaagccctgagcccgaca
cccgaacgcggctga
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