KEGG   ORTHOLOGY: K21262
Entry
K21262                      KO                                     
Symbol
calG4
Name
calicheamicin aminopentosyltransferase [EC:2.4.2.-]
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Reaction
R11420  dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose:calicheamicin-PsAg 4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentosyltransferase
R11421  dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose:calicheamicin-alpha3(I) 4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21262  calG4; calicheamicin aminopentosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21262  calG4; calicheamicin aminopentosyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K21262  calG4; calicheamicin aminopentosyltransferase
Other DBs
COG: COG1819
CAZy: GT1
Genes
AMOG: QRX60_49350
SAQ: Sare_2021
AG: AAM70365(calG4)
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Zhang C, Griffith BR, Fu Q, Albermann C, Fu X, Lee IK, Li L, Thorson JS
  Title
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions.
  Journal
Science 313:1291-4 (2006)
DOI:10.1126/science.1130028
LinkDB

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