KEGG   ORTHOLOGY: K21284
Entry
K21284                      KO                                     
Symbol
acmA, sibE
Name
3-hydroxy-4-methylanthranilate adenylyltransferase [EC:2.7.7.97]
Reaction
R11554  ATP:3-hydroxy-4-methylanthranilate adenylyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K21284  acmA, sibE; 3-hydroxy-4-methylanthranilate adenylyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.97  3-hydroxy-4-methylanthranilate adenylyltransferase
     K21284  acmA, sibE; 3-hydroxy-4-methylanthranilate adenylyltransferase
Other DBs
COG: COG0318
Genes
KGR: JJJ10_13575
KLM: BWI76_15080
VRU: RND59_08015
PCEL: HUB94_18035
NBR: O3I_021160
NOZ: DMB37_35945
NHU: H0264_30690
SANL: KZO11_29675
SGRF: SGFS_035550 SGFS_087230
SCB: SCAB_69851
SBH: SBI_01606
SAUH: SU9_026730
KFL: Kfla_6074
AMYZ: HUW46_08673(menE_3)
KAL: KALB_2251
ACTI: UA75_06460
ACAD: UA74_06460
AHG: AHOG_06230(lcfB1)
ALO: CRK56726
ACTU: Actkin_05211(bclA_2)
SAQ: Sare_2681
MIL: ML5_4902
ACTN: L083_2872
CAI: Caci_3250
AG: ACN39728(sibE) ADG27357(acmA)
 » show all
Reference
  Authors
Pfennig F, Schauwecker F, Keller U
  Title
Molecular characterization of the genes of actinomycin synthetase I and of a 4-methyl-3-hydroxyanthranilic acid carrier protein involved in the assembly of the acylpeptide chain of actinomycin in Streptomyces.
  Journal
J Biol Chem 274:12508-16 (1999)
DOI:10.1074/jbc.274.18.12508
  Sequence
Reference
  Authors
Giessen TW, Kraas FI, Marahiel MA
  Title
A four-enzyme pathway for 3,5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin.
  Journal
Biochemistry 50:5680-92 (2011)
DOI:10.1021/bi2006114
  Sequence
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