| Entry |
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| Symbol |
sibE
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| Name |
(KEGG) 3-hydroxy-4-methylanthranilate adenylyltransferase (EC:2.7.7.97)
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| KO |
| K21284 | 3-hydroxy-4-methylanthranilate adenylyltransferase [EC:2.7.7.97] |
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| Taxonomy |
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| Lineage |
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Streptosporangiales; Streptosporangiaceae; Streptosporangium |
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| Organism |
Streptosporangium sibiricum
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| AA seq |
596 aa
MSALPSLRVPTLPVAFEAAARAAGDRIALEYGSSSITYRELDAAANRFARRLLREGVTPG
SRVGLHMTRCLELYIAMIGLLKAGAVVVPLNPSHPVTVRRSVVREADLPLTLRDVPAGLS
SVTVERDVHELLAAGADLDDTSPGLCTDPESTAFILFTSGSTGRPRGVRIAHRGIARVAS
YNGEVEVRPDDCFLQLAPYSFAASTTDIWLSLLHGARVVVLPSQLPSLPKLAHTIKEYGV
TFLNLPGGLMNLLIDAHPEAFAKVRTVIVSGDFPSAPHLARVMKAVPGTVYNAFGCTENS
ALTAVHPMTPEDLQLGVVPIGLPLPGVGLHVLGEDMTPCAPGEVGEMHISGAGLAQGYLG
LPEETAAKFPTVDGVRMLRTGDWARTTPAGEVVLVGRTDQMVKIRGFRVELREVELAADQ
SGLVEKAVVRAVDATDGQKELVLFCTTATGEAPSIEALLADLKSRLPDYMLPARVHHLAE
LPVNVNGKLDRMALREPRAVLVEPDGTAQQQPVVRDIIATTVTRLLAVVTGREPIGVSDS
FLASGANSLQVIQLAASLHDVMGVDVRPEDIFQLDNAESLAGHIRALRQGHREVPA |
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| Reference |
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| Authors |
Li W, Khullar A, Chou S, Sacramo A, Gerratana B |
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| Title |
Biosynthesis of sibiromycin, a potent antitumor antibiotic. |
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| Journal |
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| Reference |
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| Authors |
Giessen TW, Kraas FI, Marahiel MA |
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| Title |
A four-enzyme pathway for 3,5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin. |
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| Journal |
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