KEGG ORTHOLOGY: K21411

ORTHOLOGY: K21411

Entry

K21411                      KO

Symbol

ANKLE1, LEM3

Name

ankyrin repeat and LEM domain-containing protein 1

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K21411  ANKLE1, LEM3; ankyrin repeat and LEM domain-containing protein 1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Other factors with a suspected DNA repair function
   Nucleases
    K21411  ANKLE1, LEM3; ankyrin repeat and LEM domain-containing protein 1

Genes

HSA:	126549(ANKLE1)

PTR:	468765(ANKLE1)

PPS:	100988026(ANKLE1)

GGO:	101148681(ANKLE1)

PON:	100455611(ANKLE1)

NLE:	100599990(ANKLE1)

HMH:	116478661(ANKLE1)

MCC:	719709(ANKLE1)

MCF:	102123498(ANKLE1)

MTHB:

126942391

MNI:	105490767(ANKLE1)

CSAB:

103234129(ANKLE1)

CATY:

105601660(ANKLE1)

PANU:

100997209(ANKLE1)

TGE:	112613162(ANKLE1)

MLEU:

105547471(ANKLE1)

RRO:	104660981(ANKLE1)

RBB:	108534291(ANKLE1)

TFN:	117076485(ANKLE1)

PTEH:

111554330(ANKLE1)

CANG:

105500311(ANKLE1)

CJC:	100391435(ANKLE1)

SBQ:	101029544(ANKLE1)

CIMI:

108284503(ANKLE1)

CSYR:

103254005(ANKLE1)

MMUR:

105866268(ANKLE1)

LCAT:

123639299(ANKLE1)

PCOQ:

105818189(ANKLE1)

OGA:	100958615(ANKLE1)

MMU:	234396(Ankle1)

MCAL:

110300700(Ankle1)

MPAH:

110336801(Ankle1)

RNO:	361122(Ankle1)

MCOC:

116069510(Ankle1)

ANU:	117721926(Ankle1)

MUN:	110563531(Ankle1)

CGE:	100753605(Ankle1)

MAUA:

101834954(Ankle1)

PROB:

127217240(Ankle1)

PLEU:

114709589(Ankle1)

MORG:

121462991(Ankle1)

MFOT:

126492216

AAMP:

119813022(Ankle1)

HGL:	101698380(Ankle1)

CPOC:

100731908(Ankle1)

CCAN:

109695612(Ankle1)

DORD:

105994718(Ankle1)

DSP:	122100812(Ankle1)

PLOP:

125348891(Ankle1)

NCAR:

124968934

MMMA:

107145332(Ankle1)

OPI:	101531044(ANKLE1)

TUP:	102476170(ANKLE1)

GVR:	103596824(ANKLE1)

CFA:	610155(ANKLE1)

CLUD:

112666910(ANKLE1)

VVP:	112913179(ANKLE1)

VLG:	121495802(ANKLE1)

NPO:	129522369(ANKLE1)

AML:	100470996(ANKLE1)

UMR:	103675183(ANKLE1)

UAH:	113256596(ANKLE1)

UAR:	123780035(ANKLE1)

ELK:

111144122

LLV:

125082618

MPUF:

101675938(ANKLE1)

MNP:	132011146(ANKLE1)

MLK:	131823716(ANKLE1)

NVS:	122909617(ANKLE1)

ORO:	101364013(ANKLE1)

EJU:	114226654(ANKLE1)

ZCA:	113917842(ANKLE1)

MLX:	118005576(ANKLE1)

NSU:	110574447(ANKLE1)

LWW:	102733044(ANKLE1)

FCA:	101082551(ANKLE1)

PYU:	121011278(ANKLE1)

PCOO:

112852374(ANKLE1)

PBG:	122486591(ANKLE1)

PVIV:

125154383(ANKLE1)

LRUF:

124524116

PTG:	102953808(ANKLE1)

PPAD:

109247563(ANKLE1)

PUC:

125929203

AJU:

106969099

HHV:	120239219(ANKLE1)

BTA:	537502(ANKLE1)

BOM:	102268674(ANKLE1)

BIU:	109561444(ANKLE1)

BBUB:

102391427(ANKLE1)

BBIS:

104992665(ANKLE1)

CHX:	102175386(ANKLE1)

OAS:	101115620(ANKLE1)

BTAX:

128051557(ANKLE1)

ODA:	120864650(ANKLE1)

CCAD:

122440699(ANKLE1)

MBEZ:

129559038(ANKLE1)

SSC:	100620785(ANKLE1)

CFR:	102509613(ANKLE1)

CBAI:

105082672(ANKLE1)

CDK:	105101840(ANKLE1)

VPC:	102541589(ANKLE1)

BACU:

103018568(ANKLE1)

BMUS:

118892419(ANKLE1)

LVE:	103075377(ANKLE1)

OOR:	101288597(ANKLE1)

DLE:	111166668(ANKLE1)

PCAD:

102989021(ANKLE1)

PSIU:

116751371(ANKLE1)

NASI:

112414684(ANKLE1)

EPZ:	103563783(ANKLE1)

EAI:	106846876(ANKLE1)

MYB:	102238814(ANKLE1)

MYD:	102756592(ANKLE1)

MMYO:

118652565(ANKLE1)

MLF:	102427992(ANKLE1)

PKL:	118706618(ANKLE1)

EFUS:

103300923(ANKLE1)

MNA:	107534336(ANKLE1)

DRO:	112305032(ANKLE1)

SHON:

118975139(ANKLE1)

AJM:	119046796(ANKLE1)

PDIC:

114503251(ANKLE1)

PHAS:

123828322(ANKLE1)

MMF:	118643825(ANKLE1)

PPAM:

129074821(ANKLE1)

HAI:	109382493(ANKLE1)

RFQ:	117038562(ANKLE1)

PALE:

102882181(ANKLE1)

PGIG:

120606510(ANKLE1)

PVP:	105296678(ANKLE1)

RAY:	107517259(ANKLE1)

MJV:	108384095(ANKLE1)

TOD:	119242230(ANKLE1)

SARA:

101557465(ANKLE1)

SETR:

126030213(ANKLE1)

LAV:	100668363(ANKLE1)

TMU:

101348889

ETF:	101663258(ANKLE1)

MDO:	100016110(ANKLE1)

SHR:	100922544(ANKLE1)

AFZ:

127545075

PCW:	110196174(ANKLE1)

OAA:	100090385(ANKLE1)

GGA:	100857739(ANKLE1)

PCOC:

116235747(ANKLE1)

MGP:	100544423(ANKLE1)

CJO:	107325432(ANKLE1)

TPAI:

128088955(ANKLE1)

LMUT:

125684837(ANKLE1)

NMEL:

110388926(ANKLE1)

OMA:	130264594(ANKLE1)

PHI:	106628874(ANKLE1)

MMEA:

130584822(ANKLE1)

HRT:	120748169(ANKLE1)

FPG:	101915361(ANKLE1)

FCH:	102055791(ANKLE1)

CLV:	102091928(ANKLE1)

TALA:

116960358(ANKLE1)

ACHC:

115349240(ANKLE1)

HLE:	104829188(ANKLE1)

AGEN:

126042149

RTD:	128900622(ANKLE1)

AROW:

112965594(ANKLE1)

DNE:	112995599(ANKLE1)

ASN:	102380717(ANKLE1)

AMJ:	102575861(ANKLE1)

CPOO:

109318680(ANKLE1)

GGN:	109288756(ANKLE1)

CMY:	102943242(ANKLE1)

CCAY:

125627033(ANKLE1)

DCC:	119848263(ANKLE1)

CPIC:

101937760(ANKLE1)

TST:	117868852(ANKLE1)

CABI:

116839050(ANKLE1)

MRV:	120391825(ANKLE1)

ACS:	103282639(ankle1)

PVT:	110072498(ANKLE1)

SUND:

121937259(ANKLE1)

PBI:	103053641(ANKLE1)

TSR:	106539626(ANKLE1)

PGUT:

117670568(ANKLE1)

VKO:	123018713(ANKLE1)

PMUA:

114588633(ANKLE1)

PRAF:

128405644(ANKLE1)

ZVI:	118087069(ANKLE1)

GJA:	107122091(ANKLE1)

STOW:

125433308(ANKLE1)

XLA:

108712891

XTR:	100498215(ankle1)

NPR:	108788803(ANKLE1)

RTEM:

120916197(ANKLE1)

BBUF:

120990949(ANKLE1)

BGAR:

122927021(ANKLE1)

MUO:	115480674(ANKLE1)

GSH:	117364587(ANKLE1)

DRE:	406563(zgc:85936)

SRX:	107727149 107757734

SANH:

107662683 107671266

SGH:	107570965 107575641

CCAR:

109108983(ankle1)

CAUA:

113119130(ankle1)

CGIB:

127979058 127979187

PTET:

122340530(ankle1)

LROH:

127161497(ankle1)

OMC:	131526132(ankle1)

PPRM:

120464712(ankle1)

RKG:	130077965(ankle1)

MAMB:

125274636(ankle1)

CIDE:

127501008

MASI:

127421055

TROS:

130567387(ankle1)

TDW:	130415555(ankle1)

MANU:

129454680(ankle1)

IPU:

108257283

IFU:	128600179(ankle1)

PHYP:

113546313(ankle1)

SMEO:

124375708(ankle1)

TFD:	113649586(ankle1)

TVC:	132837492(ankle1)

AMEX:

103038794(ankle1)

EEE:	113581131(ankle1)

TRU:	101065376(ankle1)

TFS:	130528693(ankle1)

TNG:	GSTEN00022912G001

LCO:

104928142

NCC:	104958197(ankle1)

TBEN:

117495078(ankle1)

CGOB:

115006579

PGEO:

117445838(ankle1)

GACU:

117544282(ankle1)

EMAC:

134869207(ankle1)

ELY:	117253380(ankle1)

EFO:	125895379(ankle1)

PLEP:

121963311(ankle1)

SLUC:

116055365(ankle1)

ECRA:

117950895(ankle1)

ESP:

116695461

PFLV:

114561470

GAT:	120824193(ankle1)

PPUG:

119216987(ankle1)

AFB:	129094453(ankle1)

CLUM:

117729392(ankle1)

PSWI:

130193974(ankle1)

MSAM:

119900565(ankle1)

SCHU:

122877559(ankle1)

CUD:	121512721(ankle1)

ALAT:

119028795(ankle1)

MZE:	101465114(ankle1)

ONL:

100700482

OAU:	116335563(ankle1)

OLA:	101155416(ankle1)

OML:	112150505(ankle1)

CSAI:

133458512(ankle1)

XMA:	111609781(ankle1)

XCO:	114151329(ankle1)

XHE:	116726424(ankle1)

PRET:

103463452(ankle1)

PFOR:

103130172(ankle1)

PLAI:

106948510(ankle1)

PMEI:

106922349(ankle1)

GAF:

122838878

PPRL:

129375587(ankle1)

CVG:	107083688(ankle1)

CTUL:

119787688(ankle1)

GMU:	124874569(ankle1)

NFU:	107392765(ankle1)

KMR:	108234261(ankle1)

ALIM:

106519195(ankle1)

AOCE:

111574892 111574894

MCEP:

125008830(ankle1)

CSEM:

103394013(ankle1)

POV:

109636674

SSEN:

122760773(ankle1)

HHIP:

117760432(ankle1)

HSP:	118121421(ankle1)

SMAU:

118318467(ankle1)

LCF:

108881216

SDU:

111234574

SLAL:

111652432

XGL:	120791174(ankle1)

HCQ:

109519106

SSCV:

125967560

SBIA:

133503876(ankle1)

PEE:

133406699

PTAO:

133480538(ankle1)

BPEC:

110160018(ankle1)

MALB:

109958296(ankle1)

BSPL:

114854610(ankle1)

SJO:	128362247(ankle1)

SASA:

106574192

STRU:

115151484(ankle1)

OTW:	112239859(ankle1)

OMY:	110528311(ankle1)

OGO:	123996636(ankle1)

ONE:	115109014(ankle1)

OKI:

109889014

OKE:	118401590(ankle1)

SALP:

111952862(ankle1)

SNH:	120053601(ankle1)

CCLU:

121577101(ankle1)

ELS:	105026907(ankle1)

PKI:	111860430(ankle1)

AANG:

118226205(ankle1)

LOC:	107079681(ankle1)

PSPA:

121301537(ankle1) 121310455

ARUT:

117401280 117966193

LCM:	102361893(ANKLE1)

CMK:	103182092(ankle1)

RTP:	109927675(ankle1)

CPLA:

122565447(ankle1)

HOC:	132829199(ankle1)

BFO:

BBEL:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG42391(CG42391) Dmel_CG8679(CG8679)

DER:	113564322 26527100

DSE:

116801012

DSI:	Dsimw501_GD27671(Dsim_GD27671) Dsimw501_GD29386(Dsim_GD29386)

DYA:	Dyak_GE28461

DAN:

6498376

DSR:	110177742 110182732

DPO:	26533090 4816544

DPE:

6596345

DMN:	108163087 117189830

DWI:	26528791 6641885

DGR:

6562703

DMO:	Dmoj_GI17551

DAZ:	108610277 108615827

DNV:	115562553 115564122

DHE:	111602310 111602591

DVI:

CCAT:

BDR:

RZE:

AOQ:

TDA:	119668961 119669333

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

125766639 125767831 125769450

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ004996 CpipJ_CPIJ010294 CpipJ_CPIJ020128

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100124037 100679850

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_214314

BANY:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

API:

DNX:

AGS:

RMD:

ACOO:

CLEC:

HHAL:

PHU:	Phum_PHUM388320

FOC:

TPAL:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_54711 DAPPUDRAFT_62611 DAPPUDRAFT_70389

DMK:

DPZ:

PVM:

PJA:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DFR:

CSCU:

PTEP:

UDV:

SDM:

PMEO:

CEL:	CELE_F42H11.2(lem-3)

CBR:	CBG_03727(Cbr-lem-3)

CRQ:	GCK72_000535

LOA:	LOAG_04249

TSP:

Tsp_11594

HRO:	HELRODRAFT_70669

PCAN:

112553529 112554468 112554469

GAE:

HRF:

HRJ:

CRG:

CVN:

MYI:

PMAX:

MCAF:

MMER:

DPOL:

OBI:

OSN:

LAK:	106154754 106159235

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_2710

AQU:	105313031 105315712

» show all

Reference

PMID:22399800

Authors

Brachner A, Braun J, Ghodgaonkar M, Castor D, Zlopasa L, Ehrlich V, Jiricny J, Gotzmann J, Knasmuller S, Foisner R

Title

The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo.

Journal

J Cell Sci 125:1048-57 (2012)
DOI:10.1242/jcs.098392

Sequence

[hsa:126549]

LinkDB

DBGET integrated database retrieval system