Entry Symbol rosA
Name 8-amino-8-demethylriboflavin N,N-dimethyltransferase [EC:
2.1.1.343 ]
Pathway map00998 Biosynthesis of various antibiotics
map01110 Biosynthesis of secondary metabolites
Module M00890 Roseoflavin biosynthesis, FMN => roseoflavin
Reaction R11778 S-adenosyl-L-methionine:8-amino-8-demethylriboflavin N,N-dimethyltransferase
R11779 S-adenosyl-L-methionine:8-amino-8-demethylriboflavin N-methyltransferase
R11780 S-adenosyl-L-methionine:8-demethyl-8-(methylamino)riboflavin N-methyltransferase
Brite KEGG Orthology (KO) [BR:ko00001 ]ko01000 ] BRITE hierarchy Genes Taxonomy UniProt Reference Authors Jankowitsch F, Kuhm C, Kellner R, Kalinowski J, Pelzer S, Macheroux P, Mack M
Title A novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis.
Journal Sequence Reference Authors Tongsook C, Uhl MK, Jankowitsch F, Mack M, Gruber K, Macheroux P
Title Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin.
Journal Sequence LinkDB All DBs
