KEGG   ORTHOLOGY: K22569
Entry
K22569                      KO                                     
Symbol
AF520
Name
(+)-exo-beta-bergamotene synthase [EC:4.2.3.211]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00969  Fumagillin biosynthesis, farnesyl-PP => fumagillin
Reaction
R13104  (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-exo-beta-bergamotene-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K22569  AF520; (+)-exo-beta-bergamotene synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.211  (+)-exo-beta-bergamotene synthase
     K22569  AF520; (+)-exo-beta-bergamotene synthase
Genes
MAJ: MAA_08344
MBRN: 90967588(af520_0)
AFM: AFUA_8G00520
Reference
  Authors
Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y
  Title
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway.
  Journal
J Am Chem Soc 136:4426-36 (2014)
DOI:10.1021/ja500881e
  Sequence
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