KEGG ORTHOLOGY: K22629

ORTHOLOGY: K22629

Entry

K22629                      KO

Symbol

IL27, IL27A

Name

interleukin 27 subunit alpha

Pathway

map04060

Cytokine-cytokine receptor interaction

map04630

JAK-STAT signaling pathway

map04659

Th17 cell differentiation

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K22629  IL27, IL27A; interleukin 27 subunit alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K22629  IL27, IL27A; interleukin 27 subunit alpha
09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K22629  IL27, IL27A; interleukin 27 subunit alpha
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K22629  IL27, IL27A; interleukin 27 subunit alpha
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Interleukins
   K22629  IL27, IL27A; interleukin 27 subunit alpha

Other DBs

GO:

0045523

Genes

HSA:	246778(IL27)

PTR:	112205841(IL27)

PPS:	100994582(IL27)

GGO:	101133023(IL27)

PPYG:

129015104(IL27)

NLE:	100605770(IL27)

HMH:	116470248(IL27)

SSYN:

129492891(IL27)

MCC:	708678(IL27)

MCF:	102145935(IL27)

MTHB:

126944485

MNI:	105482870(IL27)

CSAB:

103230386(IL27)

CATY:

105598730(IL27)

PANU:

101005375(IL27)

TGE:	112614578(IL27)

MLEU:

105541390(IL27)

RRO:	104682151(IL27)

RBB:	108523675(IL27)

TFN:	117087593(IL27)

PTEH:

111526940(IL27)

CANG:

105505625(IL27)

CJC:	100403729(IL27)

SBQ:	101043645(IL27)

CIMI:

108296634(IL27)

ANAN:

105725515(IL27)

CSYR:

103252096(IL27)

MMUR:

105871135(IL27)

LCAT:

123632785(IL27)

PCOQ:

105823123(IL27)

OGA:	100958612(IL27)

MMU:	246779(Il27)

MCAL:

110298592(Il27)

MPAH:

110337409(Il27)

RNO:	365368(Il27)

MCOC:

116100906(Il27)

ANU:	117695893(Il27)

MUN:	110547944(Il27)

CGE:	100753480(Il27)

MAUA:

101828527(Il27)

PROB:

127227780(Il27)

PLEU:

114686671(Il27)

MORG:

121457920(Il27)

MFOT:

126488266

AAMP:

119826351(Il27)

NGI:	103726430(Il27)

HGL:	101724119(Il27)

CPOC:

100724612(Il27)

CCAN:

109682387(Il27)

DORD:

105981797(Il27)

DSP:	122096316(Il27)

PLOP:

125341061(Il27)

NCAR:

124970281

MMMA:

107146899(Il27)

OCU:

100349321

OPI:	101529694(IL27)

TUP:	102484290(IL27)

GVR:	103595600(IL27)

CFA:	607880(IL27)

CLUD:

112640038(IL27)

VVP:	112929372(IL27)

VLG:	121486088(IL27)

NPO:	129520221(IL27)

AML:	100472637(IL27)

UMR:	103657820(IL27)

UAH:	113267636(IL27)

UAR:	123784593(IL27)

ELK:

111162322

LLV:

125090677

MPUF:

101686546(IL27)

MNP:	132026771(IL27)

MLK:	131819319(IL27)

NVS:	122895340(IL27)

ORO:	101379990(IL27)

EJU:	114214497(IL27)

ZCA:	113933284(IL27)

MLX:	117999650(IL27)

NSU:	110589783(IL27)

LWW:	102743590(IL27)

FCA:	101093822(IL27)

PYU:	121022509(IL27)

PCOO:

112856416(IL27)

PBG:	122471505(IL27)

PVIV:

125154329(IL27)

LRUF:

124518070

PTG:	102970427(IL27)

PPAD:

109256526(IL27)

PUC:

125928645

AJU:

106966164

HHV:	120242274(IL27)

BTA:	614927(IL27)

BOM:	102274852(IL27)

BIU:	109578638(IL27)

BBUB:

102408812(IL27)

BBIS:

104986616(IL27)

CHX:	102183199(IL27)

OAS:	101122495(IL27)

BTAX:

128043707(IL27)

ODA:	120882620(IL27)

CCAD:

122433131(IL27)

MBEZ:

129545492(IL27)

SSC:	493187(IL27)

CFR:	102509255(IL27)

CBAI:

105082882(IL27)

CDK:	105102800(IL27)

VPC:	102535310(IL27)

BACU:

103000306(IL27)

BMUS:

118881693(IL27)

LVE:	103077625(IL27)

OOR:	101287970(IL27)

DLE:	111182189(IL27)

PCAD:

102983052(IL27)

PSIU:

116739802(IL27)

NASI:

112399188(IL27)

ECB:	100066317(IL27)

EPZ:	103562740(IL27)

EAI:	106845641(IL27)

MYB:	102238780(IL27)

MYD:	102761174(IL27)

MMYO:

118652913(IL27)

MLF:	102439721(IL27)

PKL:	118704902(IL27)

EFUS:

103300828(IL27)

MNA:	107541003(IL27)

DRO:	112304741(IL27)

AJM:	119040950(IL27)

PDIC:

114507042(IL27)

PHAS:

123825469(IL27)

MMF:	118642332(IL27)

PPAM:

129078138(IL27)

HAI:	109385950(IL27)

RFQ:	117019597(IL27)

PALE:

102888906(IL27)

PGIG:

120620133(IL27)

PVP:	105304605(IL27)

RAY:	107515816(IL27)

MJV:	108407621(IL27)

TOD:	119242349(IL27)

SARA:

101538205(IL27)

SETR:

126029894(IL27)

LAV:	100657097(IL27)

TMU:

101361466

ETF:	101644043(IL27)

DNM:	101447686(IL27)

MDO:	100014555(IL27)

GAS:	123230793(IL27)

SHR:	100917661(IL27)

AFZ:

127555979

PCW:	110222073(IL27)

TVP:	118832168(IL27)

OAA:	100680688(IL27)

AMJ:	106739389(IL27)

ACS:

ASAO:

PVT:

SUND:

PBI:	112541632(IL27)

PMUR:

114922226

CTIG:

120304576

TSR:	106557069(IL27)

PGUT:

117669159

VKO:	123032235(IL27)

PMUA:

ZVI:

HCG:

STOW:

EMC:

DRE:

SRX:	107734131 107746434

SANH:

107661243 107663373

SGH:	107548437 107596189

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

MASI:

TROS:

TDW:

MANU:

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

TRN:

AMEX:

EEE:

CHAR:

TFS:

LCO:

NCC:

TBEN:

PGEO:

GACU:

EMAC:

ELY:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

CLUM:

PSWI:

MSAM:

SCHU:

CUD:

ALAT:

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

NWH:

AOCE:

MCEP:

CSEM:

POV:

SSEN:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

MALB:

BSPL:

SJO:

SASA:

STRU:

OTW:	112228678 112257729

OMY:	110533775 110537349

OGO:	123999176 124009376

ONE:

115135791

OKI:	109884588 109892638

OKE:	118390209 118391270

SALP:

111950652 111980737

SNH:	120044290 120056694

CCLU:

121579984

ELS:

109615981

SFM:	108921210 108933469

AANG:

118235404 118235405

LOC:	102683276 102683479

PSPA:

ARUT:

LCM:

CMK:

HOC:

LERI:

Reference

PMID:12121660

Authors

Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D, Kastelein RA

Title

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.

Journal

Immunity 16:779-90 (2002)
DOI:10.1016/S1074-7613(02)00324-2

Sequence

[hsa:246778]

LinkDB

DBGET integrated database retrieval system