KEGG ORTHOLOGY: K22759

ORTHOLOGY: K22759

Entry

K22759                      KO

Symbol

CHCHD10

Name

coiled-coil-helix-coiled-coil-helix domain-containing protein 10

Pathway

map05014

Amyotrophic lateral sclerosis

Disease

H02342

Frontotemporal dementia and amyotrophic lateral sclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K22759  CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K22759  CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial protein import machinery
  Inner mambrane
   Other inner membrane factors
    K22759  CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10

Genes

HSA:	400916(CHCHD10)

PTR:	748673(CHCHD10)

PPS:	100972184(CHCHD10)

GGO:	101143614(CHCHD10)

PON:	100436236(CHCHD10)

PPYG:

129022981(CHCHD10)

NLE:	100607802(CHCHD10)

HMH:	116459160(CHCHD10)

SSYN:

129467368(CHCHD10)

MCC:	720205(CHCHD10)

MCF:	102132787(CHCHD10)

MTHB:

126929541

MNI:	105497393(CHCHD10)

CSAB:

103223022(CHCHD10)

CATY:

105599387(CHCHD10)

PANU:

101002830(CHCHD10)

TGE:	112633781(CHCHD10)

MLEU:

105530419(CHCHD10)

RRO:	104667426(CHCHD10)

RBB:	108540429(CHCHD10)

TFN:	117096574(CHCHD10)

PTEH:

111522027(CHCHD10)

CANG:

105525282(CHCHD10)

CJC:	100387895 100391224(CHCHD10)

SBQ:	101037322(CHCHD10)

CIMI:

108282235(CHCHD10)

ANAN:

105718450(CHCHD10)

CSYR:

103268857(CHCHD10)

MMUR:

105877813(CHCHD10)

LCAT:

123625640(CHCHD10)

ERUF:

138401565(CHCHD10)

PCOQ:

105810221(CHCHD10)

OGA:	100953229(CHCHD10)

MMU:	103172(Chchd10)

MCAL:

110303324(Chchd10)

MPAH:

110326945(Chchd10)

RNO:	361824(Chchd10)

MCOC:

116074774(Chchd10)

ANU:	117724527(Chchd10)

ASYL:

127670224(Chchd10) 127680372

MUN:	110558685(Chchd10)

CGE:	100766619(Chchd10)

MAUA:

101841884(Chchd10)

PROB:

127224117(Chchd10)

PLEU:

114696503(Chchd10)

PMAV:

102904223(Chchd10)

MORG:

121434719 121435614(Chchd10) 121459090

MFOT:

126502393

AAMP:

119823212(Chchd10)

CNL:	130862101(Chchd10)

NGI:	103740072(Chchd10)

HGL:	101700511(Chchd10)

CPOC:

100735227(Chchd10)

CCAN:

109698450(Chchd10)

DORD:

105984215(Chchd10)

DSP:	122095910(Chchd10)

DMER:

138808348(Chchd10)

PLOP:

125349443(Chchd10) 125349444

NCAR:

124990856

MMMA:

107147182 107154671(Chchd10)

ITI:	101966546(Chchd10) 101967963

OCU:

100350144

OPI:	101530132(CHCHD10)

OCZ:	121171912(CHCHD10)

TUP:	102497719(CHCHD10)

GVR:	103587147(CHCHD10)

CFA:	477560(CHCHD10)

CLUD:

112676942(CHCHD10)

VVP:	112907497(CHCHD10)

VLG:	121475831(CHCHD10)

NPO:	129507989(CHCHD10)

AML:	100479936(CHCHD10)

UMR:	121099902(CHCHD10)

UAH:	113247085(CHCHD10)

UAR:	123795634(CHCHD10)

ELK:

111142584

LLV:

125082526

MPUF:

101691540(CHCHD10)

MNP:	132023391(CHCHD10)

MLK:	131811533(CHCHD10)

NVS:	122902015(CHCHD10)

ORO:	101375072(CHCHD10)

EJU:	114202355(CHCHD10)

ZCA:	113913191(CHCHD10)

MLX:	117999833(CHCHD10)

MANO:

123852849(CHCHD10)

NSU:	110578399(CHCHD10)

LWW:	102735519(CHCHD10)

FCA:	101088883(CHCHD10)

PYU:	121023020(CHCHD10)

PCOO:

112870174(CHCHD10)

PBG:	122470523(CHCHD10)

PVIV:

125148729(CHCHD10)

LRUF:

124519839

LGF:	123587759(CHCHD10)

AJU:

106988291

PTG:	102965721(CHCHD10)

PPAD:

109259726(CHCHD10)

PUC:

125914873

PLEZ:

122204145(CHCHD10)

HHV:	120238866(CHCHD10)

CCRU:

144216484(CHCHD10)

BTA:	615846(CHCHD10)

BOM:	102277700(CHCHD10)

BIU:	109571481(CHCHD10)

BBUB:

102413647(CHCHD10)

BKE:	129629837(CHCHD10)

BBIS:

104989854

CHX:	106503062(CHCHD10)

OAS:	101110091(CHCHD10)

BTAX:

128062334(CHCHD10)

CSUM:

138093986(CHCHD10)

ODA:	120871286(CHCHD10)

CCAD:

122420149(CHCHD10)

MREE:

136145965(CHCHD10)

OVR:	110146521(CHCHD10)

MBEZ:

129542359(CHCHD10)

SSC:	100152325(CHCHD10)

CFR:	106728716(CHCHD10)

CBAI:

105069344(CHCHD10)

CDK:	105095208(CHCHD10)

VPC:	116279044(CHCHD10)

BACU:

102997966(CHCHD10)

BMUS:

118906874(CHCHD10)

LVE:	103071823(CHCHD10)

OOR:	101274533(CHCHD10)

LALB:

132503851(CHCHD10)

GMF:	115841901(CHCHD10)

DDP:	132436056(CHCHD10)

DLE:	111163038(CHCHD10)

PCAD:

102975051(CHCHD10)

PSIU:

116764926(CHCHD10)

PPHC:

136133098(CHCHD10)

NASI:

112412248(CHCHD10)

ECB:	100629759(CHCHD10)

EPZ:	103563712(CHCHD10)

EAI:	106837165(CHCHD10)

MYB:	102243091(CHCHD10)

MMYO:

118678529(CHCHD10)

MLF:	102441240(CHCHD10)

MDT:	132221650(CHCHD10)

MYUM:

138998192(CHCHD10)

PKL:	118725428(CHCHD10)

EFUS:

103287005(CHCHD10)

MNA:	107530481(CHCHD10)

DRO:	112301750(CHCHD10)

SHON:

119001802(CHCHD10)

AJM:	119059221(CHCHD10)

PDIC:

114509608(CHCHD10)

PHAS:

123806608(CHCHD10)

MMF:	118640116(CHCHD10)

PPAM:

129086342(CHCHD10)

HAI:	109394863(CHCHD10)

RFQ:	117017768(CHCHD10)

PALE:

102881365(CHCHD10)

PGIG:

120606857(CHCHD10)

PVP:	105289335(CHCHD10)

RAY:	107501267(CHCHD10)

MJV:	108387827(CHCHD10)

TOD:	119233670(CHCHD10)

SARA:

101559131(CHCHD10)

SFUM:

130029718(CHCHD10)

SETR:

126033743(CHCHD10)

LAV:	100667433(CHCHD10)

ETF:	101638436(CHCHD10)

DNM:	101447600(CHCHD10)

SHR:	111719535(CHCHD10)

AFZ:

127545902

PCW:	110201779(CHCHD10)

TVP:	118829255(CHCHD10)

PBRV:

138167716(CHCHD10)

MLAO:

141497192(CHCHD10)

OAA:	100092849(CHCHD10)

TACU:

119942501(CHCHD10)

GGA:	416933(CHCHD10)

PCOC:

116228496(CHCHD10)

CJO:	107321291(CHCHD10)

TPAI:

128083791(CHCHD10)

LMUT:

125701660(CHCHD10)

NMEL:

110406374(CHCHD10)

APLA:

101790647(CHCHD10)

AACU:

137841149(CHCHD10)

OJA:	118175087(CHCHD10)

ACYG:

106031290(CHCHD10)

CATA:

118252922(CHCHD10)

AFUL:

116496102(CHCHD10)

TGU:	100190359(CHCHD10)

LSR:	110481251(CHCHD10)

PMOA:

120510379(CHCHD10)

OTC:	121344387(CHCHD10)

PRUF:

121365035(CHCHD10)

ATRC:

139598835(CHCHD10)

OMA:	130259760(CHCHD10)

PHI:	102105558(CHCHD10)

PMAJ:

107211471(CHCHD10)

CCW:	120410862(CHCHD10)

ACOE:

138119178(CHCHD10)

ETL:	114061497(CHCHD10)

ZAB:	102067151(CHCHD10)

ZLE:	135454523(CHCHD10)

SVG:	106864957(CHCHD10)

MMEA:

130578044(CHCHD10)

HRT:	120760622(CHCHD10)

CFAI:

136298801(CHCHD10)

SHAB:

115614062(CHCHD10)

ANOC:

141967369(CHCHD10)

SURA:

141951204(CHCHD10)

TALA:

104368525(CHCHD10)

ACHC:

115346448(CHCHD10)

HLE:	104837031(CHCHD10)

AGEN:

126040654

HHAR:

128146393(CHCHD10)

BBUT:

142036447(CHCHD10)

GCL:

127022891

DPUB:

104309014(CHCHD10)

PPUS:

135188700(CHCHD10)

NNI:	104011476(CHCHD10)

PCRI:

104030943(CHCHD10)

PARX:

142064790(CHCHD10)

CBOR:

142090287(CHCHD10)

MAME:

142416601(CHCHD10)

CNIC:

135995227(CHCHD10)

CUCA:

104064460(CHCHD10)

GAME:

129213994(CHCHD10)

CVF:	104293716(CHCHD10)

RTD:	128917227(CHCHD10)

CRID:

134522832(CHCHD10)

LMIC:

141750716(CHCHD10)

NARQ:

141472493(CHCHD10)

TGT:	104570415(CHCHD10)

DNE:	112992788(CHCHD10)

ASN:	102385341(CHCHD10)

AMJ:	106737484(CHCHD10)

CPOO:

109312807(CHCHD10)

GGN:	109290418(CHCHD10)

CIZ:	142022767(CHCHD10)

CMY:	102940835(CHCHD10)

CCAY:

125622956(CHCHD10)

LKP:	140898535(CHCHD10)

DCC:	119843976(CHCHD10)

CPIC:

101931553(CHCHD10)

TST:	117888188(CHCHD10)

CABI:

116824321(CHCHD10)

MRV:	120385890(CHCHD10)

ACS:	100563026(chchd10)

ASAO:

132781313(CHCHD10)

PVT:

110070702

SUND:

121916551(CHCHD10)

PBI:

103054698

PMUR:

107292832(CHCHD10)

CTIG:

120303230(CHCHD10)

PGUT:

117657837(CHCHD10)

PCAE:

139321707

APRI:

131185792(CHCHD10)

PTEX:

113448103(CHCHD10)

NSS:	113432238 113432255

VKO:

123032814

PMUA:

114586331(CHCHD10)

PRAF:

128403876(CHCHD10)

ZVI:	118076442(CHCHD10)

HCG:	128338055(CHCHD10)

GJA:	107112302(CHCHD10)

STOW:

125443112(CHCHD10)

EMC:	129341255(CHCHD10)

XLA:	100037110(chchd10.L)

XTR:	100379881(chchd10)

NPR:	108794799(CHCHD10)

RTEM:

120936565(CHCHD10)

ACAT:

141141702(CHCHD10)

PADS:

140333737(CHCHD10)

BBUF:

120988729(CHCHD10)

BGAR:

122934370

DTC:	141069525(CHCHD10)

HSQ:	130282813(CHCHD10)

PCOB:

134884393(CHCHD10)

MUO:	115480061(CHCHD10)

GSH:	117347524 117366137(CHCHD10)

DRE:	393757(chchd10)

SRX:	107736934 107736936 107737885

SANH:

107662830 107692329

SGH:	107548782(chchd10) 107595707

CCAR:

109046035 109046040

CAUA:

113038773 113064101

CGIB:

127942103 127986610

PTET:

122326155(chchd10)

LROH:

127152144(chchd10)

GRF:	141292960(chchd10)

OMC:	131528802(chchd10)

PPRM:

120490717(chchd10)

RKG:	130071015(chchd10)

MAMB:

125252871(chchd10)

CIDE:

127503389

CERY:

137012516(chchd10)

MASI:

127428729 127430611

TROS:

130570346(chchd10)

TDW:	130408104(chchd10)

MANU:

129423956(chchd10)

PDAB:

135721714(chchd10)

IPU:

108279156

IFU:	128621950(chchd10)

PHYP:

113535621(chchd10)

SMEO:

124397847(chchd10)

TFD:	113663965(chchd10)

TVC:	132859884(chchd10)

CGAR:

128507738(chchd10)

NGRA:

132894881(chchd10)

TRN:	134330535(chchd10)

AMEX:

103024891(chchd10)

CMAO:

118820653(chchd10)

EEE:

113590045

CHAR:

105893293(chchd10)

SPIL:

134071068(chchd10)

ASAD:

121698262(chchd10)

LCO:	104931755(chchd10)

NCC:	104956720(chchd10)

TBEN:

117482606(chchd10)

CGOB:

115011565(chchd10)

PGEO:

117442786(chchd10)

GACU:

117556514(chchd10)

EMAC:

134865121(chchd10)

ELY:	117254885(chchd10)

EFO:	125886498(chchd10)

PLEP:

121963603(chchd10)

SLUC:

116060579(chchd10)

ECRA:

117961466(chchd10)

ESP:	116694767(chchd10)

PFLV:

114570744(chchd10)

GAT:	120832300(chchd10)

PPUG:

119226577(chchd10)

AFB:	129102675(chchd10)

CLUM:

117740456(chchd10)

PSWI:

130205459(chchd10)

CANA:

137784111(chchd10)

CVE:	137868611(chchd10)

MSAM:

119914355 119914417

SCHU:

122871318(chchd10)

EARM:

139301170(chchd10)

CUD:	121508259(chchd10)

SPUL:

138604831(chchd10)

LMIX:

132986704(chchd10)

HTC:	141803738(chchd10)

ALAT:

119021733(chchd10)

ASTR:

137599777(chchd10)

PKLU:

139198806(chchd10)

MZE:

101482224

ONL:

100703844

OAU:	116328951(chchd10)

AOCE:

111571200(chchd10)

EJA:	138213698(chchd10)

BFRE:

138614908

MCEP:

125003780(chchd10)

CSEM:

103384275(chchd10)

POV:	109627414(chchd10)

SSEN:

122770482(chchd10)

SSOE:

131467119(chchd10)

HHIP:

117776149(chchd10)

HSP:	118119054(chchd10)

PPLT:

128437135(chchd10)

SMAU:

118312479(chchd10)

LCF:

108873417

SDU:	111239859(chchd10)

SLAL:

111647631(chchd10)

XGL:	120800953(chchd10)

BPEC:

110167635(chchd10)

ENY:	140377377 140377591(chchd10)

BSPL:

114852212(chchd10)

SJO:	128369497(chchd10)

SSCO:

133992115(chchd10)

TTY:	137179671(chchd10)

GMH:	115540500(chchd10)

SASA:

106562847 106570486(chchd10)

STRU:

115159986(chchd10)

OTW:	112220070(chchd10)

OMY:	110523255(chchd10)

OGO:	123989408(chchd10)

ONE:	115128849(chchd10)

OKI:	109868727(chchd10)

OKE:	118387328(chchd10)

OMM:	135518279(chchd10)

OCLA:

139409856

SALP:

111963775 112080606

SNH:	120021384 120025888

SFON:

129818915 129863626

CCLU:

121582065(chchd10)

ELS:	105030825(chchd10)

OEP:	134038701(chchd10)

SFM:	108932968(chchd10)

PKI:	111842048(chchd10)

AANG:

118212795(chchd10)

AROT:

135239406(chchd10)

CCOG:

133142454(chchd10)

LOC:	102696013(chchd10)

PSPA:

121296787 121299540

ARUT:

117426336 117427994

PSEX:

120540924(chchd10)

LCM:	102359660(CHCHD10)

AME:

ACER:

ALAB:

ADR:

AFLR:

VCRB:

VVE:

CCIN:

HAW:

PGW:	126372257 126372258

OVI:	T265_08649

EGL:

ATEN:

XEN:

CCLM:

BGH:	BDBG_16306

» show all

Reference

PMID:26666268

Authors

Genin EC, Plutino M, Bannwarth S, Villa E, Cisneros-Barroso E, Roy M, Ortega-Vila B, Fragaki K, Lespinasse F, Pinero-Martos E, Auge G, Moore D, Burte F, Lacas-Gervais S, Kageyama Y, Itoh K, Yu-Wai-Man P, Sesaki H, Ricci JE, Vives-Bauza C, Paquis-Flucklinger V

Title

CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis.

Journal

EMBO Mol Med 8:58-72 (2016)
DOI:10.15252/emmm.201505496

Reference

PMID:20888800

Authors

Martherus RS, Sluiter W, Timmer ED, VanHerle SJ, Smeets HJ, Ayoubi TA

Title

Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association.

Journal

Biochem Biophys Res Commun 402:203-8 (2010)
DOI:10.1016/j.bbrc.2010.09.109

LinkDB

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